Indications of vitamin B6. Vitamin B6 (pyridoxine)

The role of vitamin B6 in our body can be compared to a “workhorse”, repeatedly performing more than a hundred different processes throughout the day.

Vitamin B6 is involved in more processes in the body than any other vitamin or mineral. But how much do you know about this wonderful nutrient? Unfortunately, the lack of awareness of people is such, and this is evidenced by research data, that a third of the adult population of the country does not receive an adequate amount of this valuable vitamin from food. But vitamin B6 is protection against depression and a strong healthy heart.

What can vitamin B6 do?

The role of vitamin B6 in our body can be compared to a “workhorse”, repeatedly performing more than a hundred different processes throughout the day. Vitamin B6 acts as a coenzyme - a substance that, together with enzymes, accelerates chemical reactions in cells.

Participating in the formation of red blood cells, aiding in protein synthesis, and producing brain chemicals (neurotransmitters) such as serotonin are just a few of the many functions of vitamin B6.

In addition, vitamin B6 helps prevent and treat many diseases:

• B6 helps prevent cardiovascular diseases, including strokes.
• B6 helps overcome depression.
• B6 relieves the symptoms of insomnia.
• B6 relieves asthma attacks.
• B6 treats carpal tunnel syndrome.
• B6 helps reduce PMS symptoms.

Effect of vitamin B6

Scientists believe that consuming adequate amounts of B6 through food or supplementation helps prevent heart disease. Together with folic acid and vitamin B12, vitamin B6 helps the body process the amino acid-like substance homocysteine. High levels of homocysteine ​​in the blood indicate a risk of developing heart disease and other vascular disorders.

Since vitamin B6 is a building material for the production of neurotransmitters, it is used in medical practice to reduce the likelihood of epileptic seizures, as well as to overcome depression.

Just think about it, up to 25% of cases of depression are caused by an elementary deficiency of vitamin B6.

It's no secret that many women suffer from premenstrual syndrome, vitamin B6 relieves many of the symptoms of PMS. This softening effect occurs due to the participation of this vitamin in the process of removing excess estrogen from a woman’s body.

In patients with asthma Taking vitamin B6 reduces the frequency and intensity of attacks, this is especially important for those who take theophylline for a long time.

Vitamin B6 instructions for use

Another name for vitamin B6 is pyridoxine. It is available in two forms - this pyridoxine hydrochloride or pyridoxal-5-phosphate (P-5-P). Both forms satisfy most of the human body's needs for this nutrient, but some nutritionists prefer P-5-P, believing that it is better absorbed.

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Recommended Daily Allowance for Vitamin B6 for women and men under 50 years of age, 1.3 mg per day. For people over 50 years of age: 1.5 mg per day for women and 1.7 mg for men. Therapeutic doses can be significantly higher and must be determined by a specialist.

You should definitely know that the threshold of toxicity of this nutrient was found. Long-term consumption of high doses of vitamin B6 (more than 2000 mg per day) can lead to disturbances in the functioning of the nervous system. In rare cases, prolonged use of relatively low doses - from 200 to 300 mg per day - can lead to similar consequences. Fortunately, the effects of an overdose are completely reversible when you stop taking the vitamin. Doses up to 100 mg per day are safe even with long-term use.

Current dosages: To control homocysteine ​​levels, taking 3 mg of B6 daily is sufficient, however, it is often recommended to take 50 mg daily - the decision should be made by the attending physician. To relieve symptoms of PMS, 100 mg of B6 is prescribed daily, for the treatment of carpal tunnel syndrome, 50 mg of vitamin B6 daily or a P-S-P supplement three times a day, for the treatment of asthma the same 50 mg of B6 twice a day.

Vitamin B6 is best absorbed with a single dose of no more than 100 mg. Higher therapeutic doses should be divided into several doses.

Natural sources of vitamin B6 are the most common foods: fish, poultry, meat, chickpeas, potatoes, avocados and bananas.

If you are using V6 to relieve neuralgia, consult your doctor if you experience symptoms such as numbness or tingling. Neurological symptoms include insomnia, depression, and in extreme forms, seizures and brain wave disturbances. In these cases, you should immediately stop taking the vitamin.

A recent survey found that half of women do not get the recommended daily intake of vitamin B6. Particularly low levels of vitamin B6 were detected in women taking oral contraceptives. Symptoms of a severe deficiency, which is quite rare, include skin disorders such as dermatitis, rashes around the lips and acne.

Vitamin B6 supplementation may help relieve morning sickness in pregnant women. Although the vitamin has been shown to be safe at traditionally recommended doses (25 mg per day), there are no studies to show how supplemental vitamin B6 affects child development. Women who suffer from morning sickness should consult a doctor before taking vitamin B6.

Why do you need vitamin B6 - the latest data

Vitamin B6 may prevent heart disease not only due to a decrease in the blood level of the amino acid-like substance homocysteine. The study, conducted on 1,550 patients in 19 European clinics, found that people whose vitamin B6 levels were in the bottom fifth of the sample had twice the risk of cardiovascular disease, regardless of homocysteine ​​levels.

Vitamin B6 deficiency provokes stress, anxiety and depression. Findings from a study of men who took part in bereavement support groups suggest that men with low levels of vitamin B6 are more susceptible to stress and anxiety than men with adequate levels of vitamin B6. Scientists believe that effective treatment for depression should begin with a vitamin B6 supplement rather than with antidepressants, which have many side effects. published .

P.S. And remember, just by changing your consumption, we are changing the world together! © econet

Contents:

Why is this vitamin needed, what functions does it perform? Where is he kept? Daily dosage. The danger of shortages.

Vitamin B6 is pyridoxine hydrochloride, a key element of the diet and the basis of a healthy body. The substance was discovered by accident at the beginning of the last century, but since that moment scientists have never ceased to be amazed at its positive qualities.

Main characteristics:

• easy solubility in water;
• transparency;
• inability to accumulate in the body;
• participation in chemical processes;
• complete withdrawal in 6-8 hours.

Scientists classify pyridoxine as a biologically active coenzyme. The substance is beneficial to the body and has a number of functions for its organs. It is presented in nature in the form of colorless crystals that dissolve in water, and the resulting composition cannot be mixed with essential oils and fats. When exposed to light, the element decomposes. It is able to withstand heat, but during the cooking process (frying, boiling) most of it is still lost.

What is vitamin B6 for? In what sources is it present? What are the consequences of its deficiency for humans?

Functions

Pyridoxine is a vitamin that is chemically active and is involved in many body processes. Its main actions include:

• Stimulation and acceleration of metabolic processes. The “lion’s” share of B6 is used to start and accelerate the metabolism of various types of substances - antibodies, enzymes, protective cells and mechanical components involved in the construction of skin, muscles and bone tissue. Scientists have also proven that pyridoxine improves the absorption of proteins from food and normalizes the processing of amino acids. For this reason, it is considered an important vitamin for bodybuilders and children, where weight gain and muscle growth are a common goal.
• Helps in the synthesis of neurotransmitters. Neurotransmitters are responsible for the functioning of the central nervous system (transmission of nerve impulses, organization of thought processes). In case of their deficiency, the risk of diseases and problems with the nervous system increases. Vitamin B6 normalizes the production of these vital elements. In addition, it is involved in a number of other processes that occur in the human central nervous system. It has been proven that regular intake of products with this vitamin guarantees improved memory, increased performance, improved coordination and concentration.
• Providing cells with glucose. Pyridoxine activates the body's production of elements that ensure rapid transport of glucose to cells. This means that energy levels depend on the sufficiency of B6 in the diet.
• Acceleration of hemoglobin production. The vitamin is responsible for the production of red blood cells in blood plasma. But here his participation is indirect. It acts as a catalyst (accelerator) for reactions with proteins and is involved in the production of hemoglobin.
• Normalization of amino acid metabolism. Considering why vitamin B6 is needed, it is worth noting its participation in the breakdown and production of a number of elements, including histamine, glutamine, prostaglandins and others. Each of them is important for the body.
• Helps break down fatty acids(unsaturated). The mentioned process is doubly useful - the body is provided with an additional supply of energy due to the breakdown of fats, and the risks of accumulating excess weight are reduced.
• Support muscle fibers in tone. It has been proven that pyridoxine optimizes the delivery of glucose to cells, which activates metabolic processes. In addition, a sufficient level of B6 is a guarantee of heart health and stable functioning of internal organs.
• Normalization of lipid metabolism. It is known that pyridoxine is an element involved in optimizing cholesterol levels and maintaining blood vessels in proper condition. Thanks to this action, it is possible to avoid problems with the heart and blood vessels.
• Improving liver function. The effect of the element also has a positive effect on the functioning of the liver. A stable supply of vitamin guarantees tissue regeneration and disposal of harmful substances.

Daily requirement

When planning your diet, you should consider the following pyridoxine rate:

• An adult in good health needs 2-2.5 mg B6 per day. On average, this is equivalent to eating 0.6 kg of bananas or 0.3 kg of fish.
• Children immediately after birth and up to six months need 0.2-0.3 mg.
• With age, the need for the element increases. So, from the age of six months the body needs 0.5 mg, and by the age of 8-10 already in 1.5 mg per day.
• The body of women during lactation and pregnancy requires 2.5-3.0 mg vitamin a day.

The need for pyridoxine increases in the following cases:

• While taking birth control pills or medications containing estrogen.
• During pregnancy, when the body synthesizes increased amounts of estrogen.
• While on a diet. Often the inability to lose weight is caused by a deficiency of this useful element.
• During the period of taking steroids (including cortisone).
• 14 days before the start of the menstrual cycle.
• In adolescence, when the fat glands are in the active stage of work.
• When playing sports or heavy physical labor, and so on.

Why is deficiency dangerous?

Vitamin B6 deficiency develops due to metabolic disorders and poor diet. The first manifestations of deficiency:

• Deterioration in the appearance of the skin - cheilosis, seborrhea or dermatitis appears. The most susceptible areas are the areas around the nose and eyes.
• The deficiency is manifested by an itchy scalp and an increase in dandruff.
• Cracks in the corners of the mouth, jams.
• Stomatitis and so on.

If you ignore the first problems, then the deficiency leads to more serious consequences:

• Conjunctivitis and vision problems. The main reason is disruption of the normal functioning of the central nervous system.
• Problems with the nervous system - the appearance of irritability, deterioration in performance, a feeling of constant anxiety and loss of sleep.
• Malfunctions in the gastrointestinal tract. The main signs are vomiting, loss of appetite, nausea and others. Such symptoms appear in 90% of cases during pregnancy.
• Deterioration of brain function. It has already been noted that a lack of vitamin leads to a decrease in mental endurance and decreased mental flexibility.
• Malfunctions of the circulatory system, which is caused by low levels of plasma enzyme production. The problem makes itself felt by pressure surges, the appearance of anemia, vascular disease, and so on.
• Decreased immunity and excessive pain. The main reason is a decrease in the production of T-lymphocytes. The danger is that the symptom in question appears late, when the mild stages of deficiency are a thing of the past.
• Joint damage, arthritis. In this case, arthritis develops with a regular lack of the element (within 2-3 years).

Sources

To eliminate the problems discussed above, you should know the sources of pyridoxine and try to saturate your diet with them. In nature, the vitamin is produced by almost all plants and even some microorganisms. Also, animals that eat plant foods are able to accumulate it in the body. For this reason, meat products must be present in the human diet.

So, the most useful products include:

• Legumes. The main sources of pyridoxine here are beans, peas and beans, which contain an average of 0.9-1.0 mg of vitamin per 100 g.
• Sea fish(herring, mackerel). Here the B6 content reaches a level of 0.8-0.9 mg.
• Liver and kidneys- 0.6-0.7 mg.
• Tomato paste- 0.6-0.65 mg.
• bell pepper(red) - 0.4-0.5 mg.

Pyridoxine is also present in small amounts in the following products:

• chicken eggs - 0.35-0.4 mg;
• potatoes, parsley and leeks - 0.3 mg;
• berries, vegetables and fruits - up to 0.3 mg.

When planning your diet, it is worth remembering the properties of the vitamin. As mentioned at the beginning of the article, the element decomposes when exposed to elevated temperatures. It is also unstable in acidic and alkaline environments. For this reason, there is less pyridoxine in ready-made meat dishes than in bananas. To avoid deficiency, you should include greens, salads, fresh vegetables and fruits in your diet.

A small amount of the element is synthesized in the intestines, but this is not enough to meet the body’s needs.

Indications for use

Pyridoxine is prescribed for its deficiency (chronic or temporary). But there are other situations when taking an additional course is required. When should you take vitamin B6? What can it be useful for? The indications are as follows:

• alcoholism;
• CNS disorders expressed by various neuritis, chorea minor, paranoia, depression;
• toxicosis during pregnancy;
• leukopenia;
• hepatitis of different stages and types;
• atherosclerosis, pressure surges;
• AIDS;
• dermatitis;
• seasickness;
• herpes zoster and others.

In all the described cases, it is recommended to take pyridoxine in a higher dosage (as prescribed by a doctor). B6 is often included in a complex of medications for the treatment of enuresis, epilepsy and childhood autism. In addition, it is prescribed to smokers due to its ability to regulate lung function.

Interaction with other drugs

Pyridoxine actively interacts with B1 and B12. When mixing vitamins in one vessel (syringe), they can be neutralized, that is, each of the elements turns out to be useless for the body. B6 levels are also affected by the use of estrogens, which suppress its activity, which often leads to deficiency. In addition, alcohol abuse, irregular intake of corticosteroids, and penicillamine lead to deficiency.

When considering what vitamin B6 provides and including it in the diet, it is worth considering the negative impact on the body in Parkinson's disease. The effect here is twofold:

• the functioning of the nervous system is normalized, which gives a positive effect;
• the effect of therapeutic agents is suppressed, which inhibits recovery.

Medicines against seizures and tuberculosis are considered powerful antagonists. Their intake leads to a decrease in pyridoxine in the blood. Increasing B6 intake also has a suppressive effect on the mentioned drugs.

Despite the availability of the vitamin in pharmacies, you should not self-medicate. Only a doctor can determine the need for pyridoxine and the correct dosage.. This is the only way to achieve positive results and avoid problems with overdose or deficiency.

Pyridoxine, also known as vitamin B6, plays a valuable biochemical role for the functioning of the human body. Partially produced by our body in the intestines, the lion's share comes from food in three equivalent variations. Inside they are transformed into pyridoxal phosphate, accumulated by muscle tissue (80%), liver (10%). The substance dissolves in liquid, therefore it is classified as a water-soluble vitamin.

The vitamin element is directly involved in metabolism, affects normal fat, carbohydrate, and protein metabolism, transports necessary substances across the cell membrane, and nourishes tissues with energy.

The substance was discovered in 1934 during a study of dermatitis on the paws of experimental rats, and four years later it was isolated from yeast, receiving the name vitamin B6.

Lack of pyridoxine levels leads to many health problems, therefore it is prescribed separately to eliminate vitamin deficiency and hypovitaminosis, and is also present as a component of complex therapy for a number of diseases.

The role of vitamin B6 for the human body

Vital biochemical processes in key organs and systems of our body cannot occur without pyridoxine. It acts in various roles - coenzyme, stimulant, regulator, transporter, trigger for the synthesis of important elements.

Vitamin B6 has many functions:

• ensure adequate functioning of the nervous system;
• activate the metabolism of proteins, lipids, glucose, amino acids;
• absorb magnesium ions;
• promote the production of protective antibodies, T cells;
• regulate glucose levels, production of enzymes, hormones;
• remove excess fluid, prevent swelling;
• normalize hematopoiesis, the production of blood cells;
• maintain the health of the liver, blood vessels, heart;
• help cellular nutrition, deliver energy to the cellular level.

Vitamin B6 is directly responsible for the feeling of satisfaction, joy, and well-being, since it affects the synthesis of serotonin and dopamine - the hormones of happiness. Pyridoxine supports normal mental activity, memory, and emotional behavior.

Symptoms of Vitamin B6 Deficiency

Vitamin deficiency and hypovitaminosis of pyridoxine are susceptible to infants who are weaned early, pregnant women, people on antibiotic therapy, as well as those whose food is poor in the valuable element or its absorption is impaired. A lack of vitamin B6 has unpleasant consequences for your physical and mental health.

In terms of physical symptoms, the following picture emerges:

• anemia, insufficient hemoglobin level;
• convulsive conditions;
• increased blood pressure;
• formation of clots, blood clots;
• progressive dermatitis;
• seborrhea;
• headache;
• numbness in the legs;
• physical weakness;
• arthritis, neuralgia;
• cracks in the corners of the lips;
• hair loss.

Mentally and emotionally, vitamin B6 deficiency manifests itself:

• depression;
• instability of behavior;
• outbursts of aggression;
• excessive excitability;
• impaired memory and thinking;
• insomnia;
• negative mood.

A person receiving vitamin B6 in small quantities needs to adjust the diet and take additional pyridoxine to meet the body's need.

Thanks to research, the norm of physiological need for vitamin B6 for childhood and adulthood has been determined. According to the recommendation of the Ministry of Health of the Russian Federation, the dose of pyridoxine, also differentiated by gender, is divided into normal (in mg per day) and upper, equal to 25 mg/day.

In childhood, the optimal dose of the substance is:

• for newborns up to six months - 0.5;
• from six months to a year - 0.6;
• from one to two years - 0.9;
• from three to 6 years - 1.2;
• from 7 to 10 years - 1.5.

For adolescence:

• girls from 11 to 18 years old - 1.6;
• boys from 11 to 13 years old - 1.7;
• for boys from 14 to 18 years old - 2.

For adults:

• males over 19 years old - 2;
• female - 2;
• pregnant women - 2.3;
• breastfeeding - 2.5.

According to the Ministry of Health, two-thirds of Russians experience a chronic shortage of pyridoxine.

What foods contain vitamin B6

Plant and animal products rich in valuable pyridoxine derivatives help cover our need for vitamin B6.

Products are leaders in vitamin element content, allowing you to replenish the daily requirement (in grams per 100 g of product):

• rabbit meat - 0.8;
• walnut - 0.8;
• hazelnuts - 0.7;
• beef or veal liver - 0.7;
• tomato paste - 0.63;
• yeast, garlic - 0.6;
• porridge (wheat, barley) - 0.55;
• chicken pulp - 0.53;
• fish - 0.52;
• beef liver (heart, kidneys), sweet pepper - 0.51.

Vitamin B6 is found in sufficient quantities in flour, cereals, beans, bread, potatoes, tomatoes, milk, cabbage, canned fish, mushrooms, lamb, and pork.

Indications for use of vitamin B6

The beneficial effects of pyridoxine are little known to ordinary people. But the clinical effect is well known to doctors, so its use is widely practiced. The application concerns both the treatment of many diseases and the prevention of ailments associated directly or indirectly with vitamin B6 deficiency.

Indications for use for medicinal purposes are:

• anemia;
• atherosclerosis;
• hypertension, ischemia;
• thrombus formation;
• toxicosis;
• diabetes;
• dermatitis, seborrhea;
• nervous, mental disorders;
• digestive problems;
• liver diseases;
• swelling;
• infections;
• convulsions;
• tuberculosis;
• radiculitis, arthritis, neuritis;
• oncological diseases.

Preventive prescriptions apply to smokers, pregnant women, nursing mothers, athletes, and infants on artificial milk. The vitamin is useful for people engaged in intense mental or physical labor, as well as those undergoing treatment with antimicrobial drugs.

How does vitamin B6 combine with other medications?

The interaction of pyridoxine with other substances should be taken into account so that the drug is adequately absorbed and does not harm the effect of other medications.

Friendly partners of vitamin B6 are magnesium, folic acid .

Antagonists that slow down mutual penetration, vitamins B1 and B12 act. Antibiotics inhibit the activity of pyridoxine. This also applies anti-tuberculosis drugs, hormonal contraceptives.

Pyridoxine enhances the effect of diuretics and cardiac drugs (glycosides).

Pyridoxine overdose, contraindications

Clinical data on the consequences of overdose are not known. Hypervitaminosis occurs with prolonged use and accumulation of excess doses of the vitamin in tissues. Manifested by loss of protein in fibers, allergic manifestations, rash, nervous reactions, dizziness.

Vitamin B6 provokes the release of hydrochloric acid in the stomach, so its intake is limited to patients who suffer from gastritis or ulcers with high acidity.

Persons with liver, heart, and kidney problems require a careful approach.

Features of taking pyridoxine for children

A lack of vitamin B6 in a child leads to slower growth and formation of the muscle corset, anemia, dermatitis, exudative diathesis, seborrhea, and digestive disorders.

The child may experience overexcitement, sleep poorly, express anger, and often throw tantrums. Convulsions and seizures are possible.

To adequately obtain pyridoxine, it is necessary to include foods containing the necessary element in your baby’s diet. At the first signs of hypovitaminosis, it is better to contact a pediatrician and take a replenishing course.

Table of applicability of Vitamin B6

• Anemia (anemia)
  2.5-25 mg/day for three weeks, then 1.5-2.5 mg/day as maintenance therapy
  Vitamin B6 deficiency can contribute to anemia.
• Autism
  30 mg/day per 1 kg of weight under medical supervision
  Research shows that vitamin B6 may be beneficial for children with autism.
• Depression
  20 mg twice daily
  Oral contraceptives can cause the body to become deficient in vitamin B6, a nutrient essential for normal mental functioning. In such cases, supplementing with vitamin B6 can improve mood.
• High homocysteine ​​levels
  400-1000 mcg of folic acid, 10-50 mg of vitamin B6, 50-300 mcg of vitamin B12 per day
  Vitamin B6, folic acid and vitamin B12 play an important role in converting homocysteine ​​into other substances in the body.
• Morning weakness
  10-25 mg three times a day
  In two double-blind studies, taking vitamin B6 supplements significantly reduced the severity of morning sickness.
• Premenstrual syndrome (PMS)
  100-200 mg per day
  Many clinical studies show that taking vitamin B6 helps relieve PMS symptoms.
• Age-related dementia
  20 mg/day
  There is evidence that vitamin B6 (pyridoxine) supplements may improve memory performance, especially in people who suffer from age-related dementia.
• Age-related dementia
  On doctor's recommendation
  In women with cardiovascular disease or risk factors associated with low intakes of folic acid, vitamin B6, and vitamin B12, supplementation with a combination of these nutrients may protect against age-related cognitive decline.
• Asthma
  100-200 mg/day
  Vitamin B6 deficiency is common in asthmatics. Vitamin B6 supplements may reduce the frequency and severity of asthma attacks.
• Carpal tunnel syndrome
  100-300 mg/day for no more than 3 months; 50-100 mg/day after the course
  Vitamin B6 deficiency occurs in people with carpal tunnel syndrome, and vitamin B6 supplements may help relieve symptoms.
• Celiac disease
  3 mg vitamin B6, 0.8 mg folic acid, 0.5 mg vitamin B12
  Taking daily supplements of vitamin B6 (3 mg), folic acid (0.8 mg) and vitamin B12 (0.5 mg) helps relieve depression in people with celiac disease.
• Depression with PMS
  100-300 mg/day under medical supervision
  Some studies show that supplementing with vitamin B6 helps relieve depression, including depression associated with PMS.
• Intermittent claudication
  200 mg EPA, 130 mg DHA, small doses of vitamin B6, folic acid, vitamin E and alpha lipoic acid
  In one study, men with intermittent claudication who drank a fermented milk product fortified with fish oil, vitamin B6, folic acid, vitamin E, oleic acid and alpha-linolenic acid were able to walk longer distances without feeling pain than those who drank regular milk.
• Radiculitis
  50-100 mg of vitamins B1 and B6, 250-500 mcg of vitamin B12 complex three times a day
  A combination of vitamin B1, vitamin B6, and vitamin B12 can prevent a common type of back pain and may reduce the need for anti-inflammatory medications.
• Macular degeneration
  2.5 mg folic acid, 50 mg vitamin B6, 1 mg vitamin B12
  In a double-blind study of female healthcare workers who had cardiovascular disease or risk factors, daily supplements of folic acid, vitamin B6, and vitamin B12 significantly reduced the incidence of age-related macular degeneration.
• Glutamate sensitivity (glutamate allergy)
  On doctor's recommendation
  In one study, eight out of nine people stopped responding to glutamate after taking vitamin B6. Many doctors suggest that people with glutamate allergies should try vitamin B6 supplements for three months.
• Neuropathy
  On doctor's recommendation
  Taking folic acid, vitamin B12, and vitamin B6 supplements can improve neuropathy symptoms and quality of life.
• Neuropathy
  25 mg vitamin B1, 50 mg vitamin B6 per day
  Taking vitamin B1 in combination with vitamin B6 can help relieve the symptoms of diabetic neuropathy.
• High homocysteine ​​levels in pregnant women and after childbirth
  750 mg/day under medical supervision
  Women who had miscarriages were found to have high levels of homocysteine. Vitamin B6 can reduce these levels and increase the chances of a successful pregnancy.
• Schizophrenia
  On doctor's recommendation
  Vitamin B6 is used in combination with niacin in the treatment of schizophrenia.
• Caries
  Adults 20 mg per day, children 9 mg/day
  Vitamin B6 increases the growth of beneficial bacteria in the mouth and reduces the growth of harmful bacteria that cause tooth decay.
• Diabetes type 1
  
  People with diabetes often have low levels of vitamin B6. Vitamin supplementation may restore these levels and improve glucose tolerance.
• Diabetes type 2
  1800 mg/day pyridoxine alpha-ketoglutarate or 50 mg/day pyridoxine
  People with diabetes often have low levels of vitamin B6. Vitamin supplements can normalize levels and improve glucose tolerance.
• Dizziness
  On doctor's recommendation
  Research has shown that vitamin B6 is effective in reducing symptoms of dizziness.
• Acne
  On doctor's recommendation
  While not yet proven in research, some sources suggest that taking vitamin B6 may improve teenage and premenstrual acne, however, there are also suggestions that taking vitamin B6 may actually worsen acne.
• Alcohol addiction
  On doctor's recommendation
  Anxiety associated with alcohol dependence can be alleviated by taking combinations of vitamin B6, vitamin C, niacin and vitamin E.
• Alzheimer's disease
  On doctor's recommendation
  A combination of coenzyme Q10, iron (ferrous sodium citrate), vitamin B6 may improve mental health in people with Alzheimer's disease.
• Amenorrhea
  On doctor's recommendation
  Preliminary data found that vitamin B6 restored normal menstruation and normalized hormone levels in three cases of amenorrheic women who had high prolactin levels.
• Atherosclerosis
  On doctor's recommendation
  High levels of Homocysteine ​​in the blood have been associated with the development of atherosclerosis and heart disease in many studies. Taking vitamin B6 may help lower homocysteine ​​levels.
• Attention Deficit Hyperactivity Disorder
  On doctor's recommendation
  In one study, a large amount of vitamin B6 was more effective than methylphenidate (Ritalin).
• Bulimia
  On doctor's recommendation
  Vitamin B6, when taken with L-tryptophan, improves eating behavior, satiety and mood in women with bulimia.
• Celiac disease
  On doctor's recommendation
  For people with celiac disease who experience depression even after a gluten-free diet, vitamin B6 supplements may be helpful.
• Heart attack
  On doctor's recommendation
  Vitamin B6 can reduce homocysteine ​​levels in the blood. High homocysteine ​​levels are associated with an increased risk of heart attack.
• AIDS (HIV)
  On doctor's recommendation
  Vitamin B6 deficiency has been found in more than a third of HIV-positive men, and deficiency has been associated with decreased immunity in this group. Vitamin supplements may improve survival in this group.
• Hypoglycemia
  On doctor's recommendation
  Vitamin B6 helps control blood sugar levels in people with diabetes, and since there are similarities in the way the body regulates high and low blood sugar levels, it may be helpful for hypoglycemia.
• Stones in the kidneys
  On doctor's recommendation
  Taking vitamin B6 with magnesium may prevent the formation of kidney stones.
• Osgood-Schlatter disease
  On doctor's recommendation
  Some doctors have reported good results when using a combination of zinc, manganese and vitamin B6 for patients with Osgood-Schlatter disease.
• Osteoporosis associated with high homocysteine ​​levels
  On doctor's recommendation
  Homocystinuria, a condition associated with high levels of homocysteine, often causes osteoporosis. By lowering homocysteine ​​levels, vitamin B6 may help prevent osteoporosis.
• Parkinson's disease
  On doctor's recommendation
  Vitamin B6 may relieve symptoms of Parkinson's disease.
• Light sensitivity
  On doctor's recommendation
  Vitamin B6 has been used to successfully reduce reactions to sunlight.
• Before and after surgery support
  On doctor's recommendation
  In one trial, a combination of vitamins B1, B6 and B12 before and after surgery prevented postoperative decline in immune activity.
• Preeclampsia
  On doctor's recommendation
  Vitamin B6 and folic acid supplements reduce homocysteine ​​levels. Elevated levels of homocysteine ​​damage the lining of blood vessels and can lead to symptoms complicated by preeclampsia.
• Seborrheic dermatitis
  On doctor's recommendation
  One study used vitamin B6 ointment to treat seborrheic dermatitis, but taking vitamin B6 internally was not effective.
• Tardive dyskinesia
  On doctor's recommendation
  In some studies, taking vitamin B6 along with other nutrients has been linked to preventing the development of tardive dyskinesia.

Background: green - scientifically proven, orange - evidence insufficient, White - no research done

Vitamin B6(pyridoxine) is a compound that regulates the biochemistry of the human body. The molecule participates in the reaction of assimilation of unsaturated fatty acids. The compound was discovered during experiments on animals. It turned out that symmetrical dermatitis develops against the background of synthetic nutrition. In 1938, a substance effective against such dermatitis was first isolated from rice bran and yeast. He was named adermin. A year later, the structure was determined and the term “ pyridoxine«.

Why does the body need vitamin B6?

Vitamin B6 is a group of molecules of pyridoxamine, pyridoxal, pyridoxine. These substances work together, activating each other. The group is involved in the formation of antibodies, red blood cells. Adermin is involved in various chemical reactions occurring in the human body. It normalizes metabolism, activates the breakdown of lipids and is useful in the treatment. Vitamin B6 (in tablets, in food) stimulates the formation of serotonin, a hormonal substance responsible for a person’s mood and emotional stability. Thanks to this connection, adermin was nicknamed the substance of happiness.

Structural formula of Pyridoxal. Photo: upload.wikimedia.org

Structural formula of Pyridoxine (pyridoxole). Photo: User:Mysid, ru.wikipedia.org

Structural formula of Pyridoxamine. Photo: topuch.ru

Functions of Vitamin B6

• controls the level, preventing diabetes;
• stabilizes blood pressure, reducing the risk of atherosclerosis;
• reduces the concentration of fats, reducing the risk of heart and vascular diseases;
• normalizes the nervous system, since it participates in the reactions of production of substances responsible for the transmission of nerve impulses;
• removes excess fluid from tissues, relieving swelling, reducing the risk of kidney problems;
• activates mental activity;
• increases the physical resistance of the body;
• stimulates the production of antibodies, strengthening and reducing the risk of infection;
• slows down aging.

Interesting! Scientists, figuring out why the body needs vitamin B6, discovered its effect on female hormonal levels. It improves the functioning of the reproductive organs.

Properties of Vitamin B6

• Adermin is involved in the process of digestion of proteins and lipids.
• Vitamins B1, B6 are involved in the reactions of amino acid formation.
• Thanks to pyridoxine, it is transformed into niacin. This substance reduces the risk of skin and nervous diseases, relieves nausea, and normalizes the production of nucleic acids.
• An organism saturated with pyridoxine is less likely to suffer from night cramps, convulsions, paresthesia, and neuritis of the extremities.
• The substance has diuretic properties.
• Vitamin B6 is a name well known to people on. For them, it is a valuable calorizer.
• Against the background, adermin reduces the need for insulin.

Benefits of Vitamin B6

Vitamins B6 and B12 in tablets are often prescribed to diabetics. It is important to monitor the dose. If consumed in excess, this beneficial substance sharply reduces blood sugar, which can be life-threatening.

Adermin is useful for:

• anemia;
• diseases of the dermis;
• pathologies of the nervous system;
• toxicosis during pregnancy;
• leukopenia;

Travelers often visit the pharmacy to buy vitamin B6, because the drug alleviates the symptoms of airborne inflammation.

Both the combined use of vitamins B6 and B12, and the use of the substances independently, are well tolerated by the majority. The toxicity of Adermin is minimal. Individual intolerance is possible, accompanied by.

Harm of vitamin B6

Long-term use of unreasonably large doses is harmful. An overdose is indicated by:

• paresthesia;
• tingling;
• feeling of pressure in the limbs;
• loss of sensitivity.

Biological role of vitamin B6. Photo: videouroki.net

Daily value of vitamin B6

The volumes required per day are determined:

• age;
• floor;
• diet;
• bad habits.

The highest daily requirement of vitamin B6 for women is during pregnancy and lactation. At this time, you need to receive up to 4 mg of the substance daily. The standard dose for an adult per day is 2.5 mg. For children under 14 years of age, 0.3-1 mg of the daily requirement of vitamin B6 is enough; adolescents - 1.6 mg.

Therefore, it is necessary to know where vitamin B6 is found and to introduce more sources into the diet against the background of:

• pregnancy;
• lactation;
• obesity;
• abuse ;
• immunodeficiency;
• treatment with steroid drugs;
• increased stress (mental, physical);
• the need for pyridoxine increases in anticipation of the menstrual cycle.

Vitamin B6 deficiency

When forming a diet, make sure that there are foods that contain various vitamins, B6 and other compounds of group B. Adermin is well absorbed. Excess is excreted by the kidneys. The molecule does not accumulate in the body. Absorption deteriorates with a lack of magnesium, so complex formulations are recommended (for example, Solgar Magnesium with vitamin B6).

Symptoms of Vitamin B6 Deficiency

A lack of pyridoxine is indicated by:

• loss of appetite;
• nausea;
• irritability;
• cracks in the corners of the lips;
• depressed state;
• gas formation;
• sleep disturbance;
• kidney stones;
• drowsiness;
• stomatitis;
• conjunctivitis;
• Vitamin B6 deficiency in adolescence is indicated by acne. To cope with it, take Adermin and use ointments with pyridoxine.

With a lack of substance, the biological role of vitamin B6 is inhibited. Hypovitaminosis is possible with an incorrect, unbalanced diet, or the use of incorrectly stored and poorly prepared foods. The causes of hypovitaminosis can be gastrointestinal diseases, anorexia, postoperative condition, Hartnup disease, helminth infection.

Vitamin B6 for women

Vitamin B6 hypervitaminosis can be suspected by poor sleep, too vivid and well-remembered visions, dizziness,... Possible neurological disorders.

Vitamin B6 during pregnancy

The functions of vitamin B6 are to regulate the functioning of vital body systems. It is especially important that the substance is supplied in sufficient quantities during pregnancy. When carrying a child, the need for adermin increases. Vitamin B6 during pregnancy is +0.3 mg to the average norm.

Vitamin B6 for pregnant women is useful for normalizing the tone of the uterus. The inclusion of additional sources of the substance stabilizes the gastrointestinal tract, alleviates toxicosis, relieves pain, spasms, and thanks to its formula, vitamin B6 prevents the development of a number of pathologies. The daily requirement of vitamin B6 for women is up to 2.5 mg, during pregnancy - up to 4 mg.

To prevent hypovitaminosis already in the early stages of pregnancy, the gynecologist writes a prescription for vitamin B6 in Latin. Multivitamin complexes are usually recommended - and others. Pyridoxine is very rarely prescribed in liquid form (for injections). Complexes with B6 are recommended if a pregnant woman feels muscle pain, gets tired quickly, and is easily irritated.

To avoid experiencing symptoms of vitamin B6 overdose in adults, monitor the amount of the substance consumed. It is impossible to accurately measure the volumes, so they carry out weekly calculations based on the menu. If necessary, additional (medicinal) sources are introduced so that the woman receives no less than the norm established by the doctor per day. For some, 1.9 mg is enough, but more often the dose is higher - up to 4 mg. Excess vitamin B6 poses virtually no threat to anyone, because the substance is quickly eliminated from the body. If symptoms of overdose occur, report them to the gynecologist and stop taking the medications and change your diet.

Vitamin B6 for men

• The daily requirement of vitamin B6 for men is 2.5 mg. By receiving this amount of adermin, a man maintains health, reproductive status, good physical shape, and mental activity. All group B compounds regulate metabolism at the cellular level and are therefore important for the functioning of the central nervous system.
• The use of vitamin B6 helps cope with stress, improve skin, heart, and blood vessels.
• Nutrients are better absorbed and muscles work more efficiently. Trainers, explaining why men need vitamin B6, focus on the ability to activate energy metabolism. Athletes who adhere to a protein diet know best how to inject vitamin B6. Adermin is necessary to maintain the body in conditions of a limited, strict nutrition system.
• Pyridoxine is necessary to control blood sugar and eliminate cramps in the limbs.
• Vitamin B6 deficiency in men it is accompanied by a deterioration in the absorption of proteins and lipids. If there is a lack of this compound, niacin is not produced. Vitamin B6 injections are prescribed by a therapist or trainer. Usually 0.1-0.05 g of the drug is administered intramuscularly. The frequency depends on the type of disease and severity. The duration of the course is 30 days. The tablets are taken after meals. To prevent vitamin deficiency, the recommended dosage is 5 mg. To treat diseases, the medicine is prescribed for a course of 1-2 months; dose - 20-30 mg. The drug is taken 1-2 times daily.

This is interesting! Pyridoxine is synthesized by intestinal microflora.

Vitamin B6 for children

Vitamin B6 for children is necessary for normal development of the body.

• it is involved in metabolism, the functioning of the central nervous system, and the hematopoietic system;
• pyridoxine regulates insulin production;
• stimulates the production of antibodies;
• promotes the absorption of lipids and proteins;
• activates the activity of the liver and brain;
• improves skin condition.

Vitamin B6, useful for children and adolescents, is found in food and pharmaceutical preparations. To prevent vitamin deficiency, the child is given more legumes, cereals, and fruits. Healthy: beef, a variety of fish,... Pyridoxine is found in cashews, almonds, tomato juice, and grapes.

Although the beneficial properties of vitamin B6 are undeniable, medications containing adermin are prescribed only by a doctor. You cannot give complexes to children on your own, since the likelihood of an overdose is higher than that threatening adults. The doctor analyzes the child’s diet, living conditions, and body characteristics. Standards taken into account:

Knowing what vitamin B6 is responsible for, you can notice the symptoms of its deficiency. Vitamin deficiency is expressed by poor sleep, dermatitis, nausea, vomiting, and cracked lips. The mucous membranes become inflamed and irritated, the child is aggressive and complains of numbness in the limbs.

If vitamin B6 is elevated, your head hurts, your temperature rises, and convulsions are possible. The child has poor feeling in his limbs. Possible coordination problems. In acute hypervitaminosis, the patient loses consciousness. If a child develops an allergy to vitamin B6, the typical manifestation is hives.

To correct the condition, sources of vitamin B6 are identified, the intake of adermin in the body is excluded, and the diet is changed.

Vitamin B6 test

Vitamin B6 is a coenzyme of glycogen. It is involved in the production of adrenaline, norepinephrine, and hemoglobin. In the body, the substance is found in the muscles. When testing in laboratories, vitamin B6 is detected in the blood. The main way to identify a molecule is chromatography. Sometimes it's done ferrichloride test for vitamin B6.

To determine the concentration of vitamin B6, a blood test requires compliance with a number of restrictions. 8-12 hours before the procedure they stop eating, but you can drink still water without additives. You should not smoke 30 minutes before blood collection. Fluid samples are taken from a vein for testing.

The analysis is prescribed if symptoms indicating a deficiency of vitamin B6 are recorded in adults and children. The indications will be:

• dermatitis;
• diarrhea;
• cheilitis;
• stomatitis;
• gastrointestinal diseases;
• malnutrition;
• intravenous nutrition.

Blood tests are indicated to determine the level of vitamin B6 in the blood in cases of alcohol intoxication, chronic infection, prolonged fever, hypothyroidism - such patients need more adermin.

Normal readings of vitamin B6 in the blood: 8.7-27.2 ng/ml.

Exceeding the upper threshold is observed with prolonged intake of additional volumes of Adermin. Low levels are not uncommon in intestinal, kidney diseases, or treatment with antibiotics.

What foods contain vitamin B6

Knowing which foods contain vitamin B6, you can formulate your diet, avoiding hypovitaminosis.

Table 1 - Vitamin B6 content in foods

Name	Amount of mg of pyridoxine in 0.1 kg of product
Semolina	0,17
Buckwheat	0,4
Rice	0,18
Millet	0,52
Oatmeal	0,27
Cereals	0,24
Oatmeal	0,2
Pearl barley	0,54
Barley grits	0,54
Peas	0,3
Black bread	0,17
Whole wheat bread	0,3
Corn grits	0,25
Pasta	0,16
Yeast	0,58
Almond	0,3
Sunflower seeds	1,34
Cocoa powder	0,3
Halva	0,43
Walnuts	0,8
Hazelnut	0,7
Pistachios	0,5
Eggplant	0,15
Polka dots	0,17
Potato	0,3
Cabbage	0,14
Kohlrabi	0,17
Onion greens	0,15
Carrot	0,13
bell pepper	0,5
cucumbers	0,14
Chinese cabbage	0,18
Beet	0,18
Beans	0,9
Horseradish	0,7
Pumpkin	0,13
Figs	0,13
	0,38
Currant	0,14
Butter	0,3
Milk	0,2
Cheese	0,13
Cottage cheese	0,19
Beef	0,4
Pork	0,45
Liver	0,7
Kidneys	0,5
Sausage	0,2
Egg	0,14
Chum salmon	0,5
Mackerel	0,8
Halibut	0,4
Sardine	0,7
Pelamida	0,6

You need to know the benefits of vitamin B6 when planning your menu. Understanding the benefits of including adermin-rich foods in your diet makes it easier to change your eating habits if necessary. To get enough pyridoxine, eat potatoes, beans, beans, meat, cereals and fish.

Vitamin B6, which is beneficial for blood vessels, blood, and the heart, is found in especially large quantities in:

• sunflower seeds;
• beans;
• chicken liver;
• mackerel;
• walnut.

All five products are widespread, accessible, and relatively inexpensive. Keep in mind that the active form of vitamin B6 is found only in unprocessed sunflower seeds. Roasted sunflower seeds sold in stores do not contain any valuable substance.

Beans rich not only in vitamins, but also in amino acids. Its chemical composition is such that the product is almost similar to meat.

Chicken liver useful for anemia. Combining it and Glycine Forte with vitamins B1, B6, B12, they saturate the diet with useful substances that stimulate hematopoietic function. The advantage of liver is that the beneficial ingredients are not destroyed by heat treatment.

Of all fish species, the most pyridoxine was found in mackerel. It contains polyunsaturated fatty acids, potassium,. All these molecules mutually activate each other.

Walnut- the most accessible and useful in our climate zone. It is enriched with fatty acids, reduces the concentration of cholesterol in the circulatory system, and fights worms and bacteria. Among the disadvantages of nut kernels are caloric content and allergenicity.

What vitamins contain B6?

Adermin is included in many combination complexes. There are many names of preparations with vitamin B6: Magne B6, Magnelis, Ginko biloba and others. There are two forms of release: tablets, injection solutions. Adermin is prescribed for:

• activation of tissue regeneration;
• improving the condition of the central nervous system;
• prevention of heart and vascular diseases;
• treatment of dermatitis;
• metabolism stabilization;
• stimulation of hematopoietic function.

The instructions for using vitamin B6 in ampoules recommend resorting to the remedy in case of poisoning - pyridoxine is considered an effective antidote.

Popular Panangin plus vitamin B6. It is taken twice daily, 2 tablets with meals for a month. The drug reduces anxiety, improves the functioning of the central nervous system, and increases the ability to resist stress. Taking the supplement reduces the risk of atherosclerosis.

Panangin Plus Vitamin B6. Photo: natulife.ru

Helpful Motherwort with Vitamin B6. This dietary supplement is recommended for cases of aggressive, anxious behavior. It helps with diseases of the heart, blood vessels, and nervous system. The combined product is useful during periods of increased stress and fatigue.

Vitamins Magne B6- perhaps the most famous pharmacy product with adermin. The inclusion of pyridoxine increases the absorption of magnesium. The drug is useful for poor sleep, spasms, anxiety attacks and increased stress. It is prescribed as an element of complex treatment of nervous disorders. Magne B6 relieves the condition if palpitations are felt. The drug is approved from 6 years of age. It is recommended to take up to 3 ampoules (or 6 tablets) per day.

Magne B6 60 tablets. Photo: vseapteki.ru

Magne B6 has an analogue - vitamin Magnelis B6. This complex is indicated for adults daily in the amount of 6-8 tablets. It is prescribed to children if the patient’s weight is more than 20 kg. The daily norm is 4-6 tablets. Magnelis B6 is recommended to be taken when there is a reduced concentration of magnesium in the circulatory system. As soon as the indicators are equalized, the course is completed.

Magnelis B6 line. Photo: vklimakse.ru

This is interesting! Pyridoxine enhances the effect of diuretics, cardiac glycosides, glutamic acid.

Vitamin B6 in ampoules

The pyridoxine solution is packaged in 1 ml ampoules. The concentration of the drug is 50-100 mg per 1 ml. The optimal option is chosen based on the needs of the body, age and diagnosis of the patient. Liquid vitamin B6 is used less often than tablets. It is prescribed if the patient is fainting, comatose, or suffering from severe vomiting. Adermin is administered by injection for mental disorders, during the recovery period after resection of the gastrointestinal tract. In the hospital, the drug is administered by injection if the patient needs a very high dosage. This is usually a one-time event.

Pyridoxine injections are indicated for manifestations of vitamin deficiency, hypovitaminosis:

• dermatitis;
• seborrhea;
• stomatitis;
• cracks on the lips;
• sleep disorders;
• conjunctivitis;
• nausea;
• loss of appetite.

Indications for use course of injections are:

• leukopenia;
• anemia;
• hepatitis;
• radiculitis;
• neuralgia;
• neuritis;
• hypertension;
• diabetes;
• autism;
• dermatitis.

Pyridoxine is indicated in the treatment of epilepsy. It relieves severe symptoms of withdrawal from binge drinking. Adermin is an antidote for isoniazid and hydrazine. Injections are recommended if more than an hour has passed since taking a dangerous compound.

Prescription standards for:

• parkinsonism - 0.1 g daily; 20-25 injections per course;
• convulsive syndrome - 30-600 mg daily;
• depression - 0.2 g daily.

The drug is injected under the skin, into a muscle, or into a vein.

Pyridoxine hydrochloride 50 mg/ml. Photo: borimed.com

Vitamin B6 tablets

In cosmetology, vitamin B6 is valued for its ability to improve skin health and slow down aging. More often they use tablets or ointments with adermin. The following formulations are sold in pharmacies:

• monovitamins;
• multivitamin.

A specialist will help you choose the best option. For the beauty of skin, nails, and hair, vitamin B6 is usually obtained with a combined tablet product. Such drugs have a complex effect on the human body; components reinforce each other. Many complex formulations with pyridoxine have been developed. There are, for example, special products aimed at: vitamin B6 is suitable for this due to its ability to slow down the aging process. If you choose drugs to treat a specific disease, you often resort to a monovitamin product.

Pure B6 is available under the names:

• Pyridoxine hydrochloride;
• Vitamin B6;
• Bartel Drugs Vitamin B6.

Capsule, tablet contains 10-100 mg of substance.

Vitamin B6 100 mg. Photo: shop.usa-4u.eu

The drug is indicated for cheilosis, seborrhea, glossitis. He is written out against the background:

• polyneuritis;
• vomiting;
• nausea;
• conjunctivitis;
• pathologies of the central nervous system.

Due to the minimal set of contraindications, vitamin B6 (prohibited only in cases of intolerance, ischemia, etc.) is often used as an element of complex treatment:

• hepatitis A;
• anemia;
• psoriasis;
• diathesis;
• enuresis;
• leukopenia.

Average prophylactic daily dose:

• adults - up to 4 mg;
• children - up to 2 mg.

For trigeminal neuralgia, 0.3-0.4 g of adermin is prescribed. Against the background of heart failure, it is recommended to take 0.1 g of the drug daily.

Conclusion

The importance of B6 for humans cannot be underestimated. Pyridoxine is a participant in chemical reactions occurring in the body, a regulator of metabolism and processes that support life. Adermin is necessary for human health and beauty. Its deficiency is manifested by severe symptoms of hypovitaminosis and is corrected by changing the diet and taking complex medications. Multivitamins are especially important for athletes and people on a limited diet.

Vitamin B6 (pyridoxine) is a water-soluble B vitamin, poorly soluble in fats. Relatively stable at high temperatures, decomposes under the influence of light and oxygen. It is not synthesized in the body, sources of intake are food and pharmacological drugs.

What does the body need vitamin B6 for?

Benefits of taking pyridoxine

• The enzyme transaminase is secreted, which is necessary for the processing of amino acids and the regulation of protein absorption.
• Under stress, the production of biogenic amines increases.
• The bioavailability of fatty acids improves.
• The rate of biochemical reactions increases.
• Reducing the synthesis of oxalic acid reduces the risk of development and relapse of urolithiasis.
• Converts folic acid to its active form.
• Dermatological diseases are prevented.
• Thanks to the lipotropic effect, liver functioning improves.
• Reduces premenstrual pain.

For systems and organs

Nervous system

• Metabolism in the brain increases, memory improves.
• Neurotransmitters are actively synthesized - serotonin, gamma-aminobutyric acid, dopamine and norepinephrine.
• The supply of nervous tissue with nutrient substrates improves.
• Prevents and eliminates muscle spasms and tremors.

The cardiovascular system:

• Ischemia, atherosclerosis and myocardial infarction are prevented, blood is thinned and blood pressure is reduced.
• The content of potassium and sodium in the blood and intercellular fluid is normalized.
• Swelling of the face and limbs in chronic heart diseases is reduced.
• Necessary for hemoglobin synthesis, reduces cholesterol levels in the blood, and prevents thrombosis.
• Normalizes the functioning of the heart and increases its ability to relax during diastole.

Endocrine system:

• The use of glucose becomes more efficient, its level in the blood changes without sudden surges and falls.
• Maintains estrogen balance, preventing the appearance of tumors in women.
• Necessary for the synthesis of most hormones.
• Helps preserve vision in diabetes mellitus.

Vitamin B6 instructions for use

Injection: administered subcutaneously, intramuscularly or intravenously slowly, 1-2 times a day. When administered intravenously, a single dose is diluted with 1-2 ml of water for injection or isotonic sodium chloride solution immediately before use.

Pills: Take orally with a small amount of liquid, regardless of food.

Pyridoxine for hair

If there is a lack of pyridoxine in the body, the hair dries out, breaks and splits. The scalp becomes oily, dandruff appears, and hair grows poorly. Vitamin B6 has gained wide popularity among cosmetologists to eliminate such problems.

Benefits for hair

• Dry hair is hydrated because vitamin B6 retains water.
• Hair growth increases.
• Due to the soothing effect, skin itching is eliminated.
• Hair stops falling out, thickens and strengthens.
• Dandruff disappears.
• The blood supply to the roots improves, the hair becomes smooth, increases in volume and begins to shine.

The most popular masks with pyridoxine from ampoules. They must be applied to unwashed hair, covering the head with polyethylene and wrapping it in a thick towel. In case of significant hair loss, masks should be applied every other day, for preventive purposes - 2 times a week.

Hair mask recipes

1. Heat 2 teaspoons of burdock oil in a water bath and mix with an ampoule of pyridoxine. Apply to damp hair and leave for 2 hours.
2. Beat a chicken egg and mix with a tablespoon of almond oil. Add 1 ampoule of pyridoxine and vitamin B12, mix and apply to dry hair overnight. Leave for an hour, rinse with warm water and go to bed. Wash your hair with shampoo no earlier than after 8 hours.
3. Melt 2 tablespoons of honey and add 1 ampoule of vitamins A, E, B6 and B12. Stir and pour a teaspoon of sunflower oil and lemon juice into the mixture. Apply for an hour, then wash your hair with shampoo.

Vitamin B6 during pregnancy

During pregnancy, the body's need for pyridoxine increases by 1.5-2 times. It is prescribed in combination with magnesium, which increases the absorption of both elements (Magne B6). Pyridoxine eliminates morning sickness and leg cramps in the last trimester of pregnancy.

Indications for use::

• Threat of miscarriage.
• Detachment of the placenta.
• Increased uterine tone.
• Skeletal muscle cramps.
• History of difficult pregnancy and complicated childbirth.
• Frequent stress.
• Tachycardia.
• Arrhythmia.
• Hypertension.

Vitamin B6 for children

A lack of pyridoxine in the diet of children can cause severe pathologies in the development of the nervous system. If it is deficient, the child sleeps poorly and suffers from night cramps. For babies, it is important that the mother gets enough vitamin B6. Before giving the drug to children under one year of age, consultation with a pediatrician is necessary.

Daily requirement

Increasing the dose by 25-30% is necessary:

• While taking contraceptives and medications containing estrogen.
• In the last week of pregnancy.
• A week before the start of your period.
• While taking steroid-based medications.
• If you are overweight.
• For acne and inflammatory skin diseases.

Vitamin B6 indications for use

Pyridoxine is prescribed for:

• B6-hypovitaminosis.
• Anemia.
• Toxicosis during pregnancy.
• Decreased leukocyte levels.
• Meniere's disease.
• Motion sickness and seasickness.
• Inflammation in the gallbladder and liver.
• Parkinsonism, neuritis, radiculitis and neuralgia.
• Neurodermatitis, psoriasis and diathesis.
• Diabetes mellitus.
• Edema of cardiogenic origin.
• Deterioration of cardiac contractility.
• Increased blood pressure and risk of myocardial infarction.
• Depression and increased nervous tension.
• Urolithiasis.
• Obesity.
• Atherosclerosis.
• Decreased immunity.
• Deterioration of vision due to diabetes.
• Increased hematocrit.
• Hypercholesterolemia.

Assimilation

When administered intramuscularly, the bioavailability of pyridoxine is 100%. In food it is contained in the form of compounds that break down in the small intestine. With the blood, vitamin B6 enters the liver, where it undergoes dephosphorylation and then phosphorylation. The maximum concentration is observed in the liver, kidneys and myocardium.

What foods contain vitamin B6?

Where is vitamin B6 found in animal products:

• Tuna, mackerel and sardine fillets.
• Chicken and beef liver.
• Chicken fillet.
• Eggs.
• Shrimp and oysters.
• Beef and lamb.
• Dairy products.

Plant products:

• Hazelnuts, pine nuts and walnuts.
• Beans.
• Potato.
• Sea buckthorn and pomegranate.
• Horseradish and garlic.
• Bell pepper.
• Green peas, soy and lentils.
• Bananas.
• Millet.
• Yeast.

Vitamin B6 deficiency

Pyridoxine deficiency is characterized by:

• Excessive irritability, lethargy and mental dysfunction.
• Insomnia and a feeling of causeless anxiety.
• Decreased appetite and developmental delays in children.
• Convulsive syndrome.
• Flatulence.
• Formation of uroliths in the kidneys and bladder.
• Abnormal electroencephalogram readings.
• Peripheral neuritis, polyneuritis of the arms and legs.
• The development of anemia with a sufficient amount of iron in the body.
• Inflammation of the skin and mucous membranes.
• Stomatitis, rhinitis and conjunctivitis.
• Glossitis and ulceration of the oral cavity.
• Severe bleeding gums.
• Convulsive conditions in children under 7 years of age.
• Increased blood viscosity and its tendency to form clots, clogging blood vessels and causing thrombosis.
• Nausea and vomiting.
• The inability of the immune system to synthesize antibodies.

Overdose

Vitamin B6 is quickly metabolized and excreted in the urine. Exceeding dosages 50 times over several years does not lead to deterioration in health.
Increasing the dose hundreds of times can lead to:

• Peripheral blood flow disorders.
• Tachycardia and pain radiating to the left arm.
• Migraines, drowsiness and dizziness.
• Excitement and lack of coordination.
• Paresthesia of the arms and legs.
• A feeling of pressure on the limbs (stocking and glove syndrome).
• Difficulty breathing.
• Anaphylaxis, urticaria, itchy rash, redness of the skin, dermatitis, Quincke's edema and photosensitivity.
• Nausea and vomiting.
• Deterioration of the immune system's resistance to infections.
• Heartburn and increased production of gastric juice.
• Reducing folic acid content.
• Partial baldness.
• Disturbances in the blood coagulation system.
• Fainting and convulsive syndrome when large doses are administered intravenously.
• Inhibition of milk production in nursing mothers.

Long-term overdose causes a decrease in the amount of protein in skeletal muscles, liver, kidneys and heart.

Drugs and release forms

Vitamin B6 in ampoules – price 11 UAH/35 RUR for 10 ampoules of 1 ml.

Compound: pyridoxine hydrochloride – 0.05 g, water for injection – up to 1 ml.

Vitamin B6 tablets – price 9 UAH/28 RUR for 10 tablets.

Compound:

• Active ingredient– priridoxine hydrochloride 0.05 g.
• Additional components: microcrystalline cellulose, lactose monohydrate, anhydrous colloidal silicon dioxide, talc, magnesium stearate.

Compatibility

The following drug interactions have been described:

• When taken simultaneously with diuretics, pyridoxine enhances their effect.
• Combined use with hormonal contraceptives, cycloserine, penicillamine, isoniazid, hydralazine sulfate, ethionamide and immunosuppressants reduces the effectiveness of vitamin B6.
• Pyridoxine partially blocks the effect of drugs for the treatment of Parkinson's disease and weakens the pharmacological effect of phenytoin.
• When taken in combination with corticosteroid hormones, the content of pyridoxine in the body decreases.
• Simultaneous use with glutamic acid and asparkam increases the brain's resistance to hypoxia.
• The parallel use of vitamin B6 and cardiac glycosides stimulates the production of contractile proteins in the heart muscle.
• Pyridoxine prevents complications from taking tricyclic antidepressants caused by their anticholinergic effects (decreased salivation, anuria).
• Simultaneous administration with chloramphenicol derivatives reduces the risk of ophthalmic pathologies.
• Vitamin B6 is compatible with vitamin B12, but mixing them in the same container is not recommended.
• It is undesirable to mix pyridoxine with alkali solutions, iron derivatives and solutions of strong oxidizing agents.
• Do not mix vitamin B6 in the same container with solutions of adrenergic agonists, ampicillin sodium salt, amphotericin B, ascorbic acid, phytomenaion, dipyridamole, sodium oxyferiscorbone, phenothiazine derivatives (chlorpromazine), furosemide, etamsylate and euphilin.

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Kalorizator 2020 - Vitamins, instructions for medications, proper nutrition. All information is for informational purposes only. Be sure to consult a doctor during treatment.