The effect of Pharmatex on the course of bacterial vaginosis. Pharmatex - release form, instructions for use, indications, side effects, analogues and price After Pharmatex, yellow discharge

CANDLES, TAMPONS, CREAM, TABLETS
(Pharmatex)

Indications
Local contraception for any woman of reproductive age who has no contraindications, as well as in the following cases:
- the presence of temporary or absolute contraindications to the use of oral contraceptives or intrauterine device;
- in the period after childbirth and during breastfeeding;
- after termination of pregnancy;
- in the period preceding menopause;
- if necessary, occasional birth control;
- with constant use of oral contraceptives in case of missing or late taking a pill.
As additional local contraception when using a vaginal diaphragm or intrauterine device (especially if certain medications such as NSAIDs are taken at the same time).

Contraindications
- the impossibility of proper use in persons with mental disorders or persons who do not allow any intervention on the genital organs and who prevent the use of a contraceptive;
- any person unable to understand or agree with this type of contraception;
- colpitis;
- ulceration and irritation of the mucous membrane of the vagina and uterus;
- hypersensitivity to the components of the drug.

pharmachologic effect
Vaginal contraceptive.
Benzalkonium chloride is both a spermicide and an antiseptic. The active substance destroys sperm membranes. The destruction of sperm occurs in two stages: first, destruction of the flagellum, then rupture of the head, which makes fertilization impossible.
The use of Pharmatex significantly reduces the risk of pregnancy, but does not eliminate it completely.
Clinical effectiveness is determined by the adjusted Pearl index, which is less than 1 if the drug is used correctly.
In vitro preparation active regarding many pathogens that cause sexually transmitted diseases, especially Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Staphylococcus aureus, Herpes simplex type 2, HIV.
A drug not active regarding Mycoplasma spp. And weakly active in relation to Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.
In vivo, the components of the drug show some activity in the prevention of sexually transmitted diseases, but there is no evidence of this.
The drug does not affect the saprophytic vaginal microflora, incl. on Doderlein's stick.

FORM OF PHARMATEX RELEASE:

• Pills
• Candles
• Capsules
• Tampons

Dosage and administration
The frequency of use of the drug is limited by individual tolerance of the active substance and the frequency of sexual intercourse. It is possible to use Farmatex in conjunction with a vaginal diaphragm or IUD.

Side effect
Allergic reactions: burning, itching, contact dermatitis (if these occur, you should stop using Farmatex).

Pregnancy and lactation
No harmful effects associated with the use of the drug during pregnancy were found. The examination of the teratogenic properties of the final product gave negative results, as well as the examination of the teratogenic properties of the active substance itself. In addition, studies have shown that benzalkonium chloride is not absorbed into the blood. Since it has been proven that the active substance FARMATEX does not penetrate the blood and breast milk, the use of this spermicide during breastfeeding does not pose any danger.

special instructions
The effectiveness of contraception is associated solely with strict adherence to the rules of its use:
- apply systematically before each sexual intercourse;
- insert the capsule (tablet, suppository, tampon, cream) so that the selected dosage form penetrates as deeply as possible into the vagina, preferably in a lying position;
- wait for the capsule or tablet to completely dissolve in the vagina for at least 10 minutes, for the suppository - at least 5 minutes, so that the active substance is completely released;
- be sure to introduce a new capsule, tablet, dose of cream, suppository) before each repeated sexual intercourse;
- it is prohibited to use soap for toileting the genitals 2 hours before sexual intercourse and for 2 hours after sexual intercourse, because soap, even in residual quantities, destroys the active ingredient of Farmatex;
- immediately after sexual intercourse, only external toilet of the genital organs is possible only with clean water or with the help of a foaming product called Pharmatex, which does not contain soap, which contains benzalkonium chloride. Before performing vaginal irrigation, you should wait 2 hours after sexual intercourse;
- with Pharmatex inserted into the vagina, you should not take baths, swim in the sea, pool or reservoirs due to the risk of reducing the subsequent contraceptive effect;
- since Pharmatex contains benzalkonium chloride, it is necessary to interrupt its use if any vaginal diseases occur or their exacerbation;
- if there is a need to treat vaginal diseases and/or prescribe any other vaginal medication, you must wait until the end of treatment before resuming (starting) contraception with Pharmatex.

Drug interactions
The simultaneous use of FARMATEX with medications used vaginally is not recommended. Any drug introduced into the vagina can inactivate the local spermicidal effect. Destroyed by soap. You should not irrigate the vagina before and after sexual intercourse, because soap, even traces of it, destroys the active substance.

Vaginal tablets. Lying on your back, the tablet is inserted deep into the vagina no later than 10 minutes before sexual intercourse. The duration of action of the drug is 3 hours. Be sure to administer a new tablet before each repeated sexual intercourse. 1 tablet is designed for one sexual act.

Vaginal capsules. Lying on your back, the capsule is inserted deep into the vagina no later than 10 minutes before sexual intercourse. The duration of action of the drug is 4 hours. Be sure to administer a new capsule before each repeated sexual intercourse. 1 capsule is designed for one sexual act.

Vaginal suppositories. Lying on your back, the suppository is inserted deep into the vagina no later than 5 minutes before sexual intercourse. The duration of action of the drug is 4 hours. Be sure to introduce a new suppository before each repeated sexual intercourse. 1 suppository is designed for one sexual act.

Before insertion vaginal tampon it should be removed from its protective packaging. Place the middle finger of one hand in the center of the flat surface of the tampon. Spreading the lips of the vulva with the other hand, insert the tampon deep into the vagina, up to contact with the cervix. The protective effect occurs immediately and lasts 24 hours. During this period, there is no need to change the tampon, even if several sexual acts follow one another. You can remove the tampon 2 hours after the last sexual intercourse. In any case, the tampon should be removed 24 hours after insertion into the vagina. If difficulties arise with removing the tampon, you need to squat down (thereby reducing the depth of the vagina) and pull out the tampon, holding it between your index and middle fingers.

Before insertion vaginal cream The dispensing device should be installed at the end of the tube. Fill it completely (up to the ring-shaped mark or until the piston stops) so that no air bubbles form. Disconnect the dosing device from the tube. Before sexual intercourse, insert Farmatex cream deep into the vagina using a dosing device, slowly pressing the plunger. Remove the dosing device. It is easier to administer while lying down. The protective effect begins immediately and lasts for at least 10 hours. Be sure to administer a new portion of the cream before each repeated sexual intercourse. 1 serving of cream is designed for one sexual act.

Oksana Vasilievna Romashchenko
Doctor of Medical Sciences, obstetrician-gynecologist, chief researcher of the Department of Sexopathology and Andrology, Institute of Urology of the National Academy of Medical Sciences of Ukraine

Pharmatex, according to reviews from many doctors and researchers, is important not only because this drug perfectly performs its direct function - contraception. Reviews of Pharmatex indicate that it helps women suffering from various “female” diseases to solve the problem of preventing unwanted pregnancy without harming their health.

Pharmatex - reviews are important for “female” problems

The prevalence of gynecological diseases can “eclipse” only their diversity. Moreover, we are talking not only and not so much about diseases caused by sexually transmitted infections (STIs), but primarily about endocrine, immune or other non-infectious causes that negatively affect the state of a woman’s reproductive health. They are not always diagnosed in a timely manner, treatment takes a long time, sometimes the desired effect is not achieved, but... “you have to live somehow,” as the patients themselves note!

It is known that with the development of many functional pathological disorders of the female reproductive and endocrine systems, hormonal drugs are either contraindicated or simply undesirable. What, then, should patients who find themselves in a similar situation do? Don't give up on love!

To prevent unwanted pregnancy, they are advised to give preference to local or barrier methods of contraception.

Among barrier methods of contraception intended for women, a special place is given to intrauterine contraception (IUC). The introduction of an IUD is not indicated for nulliparous women due to the high risk of developing inflammatory diseases of the internal genitalia with the subsequent formation of a spectrum of reproductive disorders. Their use by women with an implemented reproductive program is permissible if the presence of inflammatory processes on the genitals is excluded (the use of intrauterine contraception against the background of inflammatory diseases of the genitals is associated with the risk of developing tubo-ovarian inflammatory formations on the appendages and generalization of infection). In addition, the introduction of intrauterine contraceptives is associated with the risk of damage to the uterus if the rules and techniques of this manipulation are violated.

Local methods - like the Pharmatex standard - are much easier to use, even when used by women at the debut of sexual relations. They are also more suitable for nulliparous women, especially those who do not have regular sexual relations. In this case, psychological problems are relative when we are talking about more significant violations of gynecological well-being. As an example - hyperplastic processes of the endometrium.

Pharmatex: reviews for endometrial hyperplasia

Hyperplastic processes of the endometrium are a whole symptom complex of pathological conditions that differ in stages, nature, etc. Hyperplastic processes are characterized by abnormal division of endometrial cells - the lining of the uterus - with its subsequent proliferation. These pathological changes in the endometrium are caused by a hormonal imbalance in the direction of increasing estrogen levels with a simultaneous decrease in progesterone. Often such changes can be predetermined by chronic inflammatory diseases of the genitals, which currently occur latently - without pronounced clinical symptoms. With endometrial hyperplasia, structural changes in the endometrium are observed. The likelihood of poor-quality transformation of cells increases, in some cases with their malignancy. The incidence of endometrial cancer in women under 40 years of age is 0.85%. Diagnosing cancer in this case is difficult (asymptomatic disease predominates), so prevention and screening in this situation are of particular importance. Women should be attentive to their condition and identify the clinical manifestations that are most common with endometrial hyperplasia:

1. Intermenstrual bleeding
2. Frequent nagging pain in the lower abdomen
3. Uterine bleeding
4. Anemia, weakness, decreased performance

Pharmatex: reviews on the use of hormone therapy

In case of endometrial hyperplasia, identification and elimination of the causes of this pathological condition is indicated. At a certain stage of treatment, it is possible to carry out hormone therapy aimed at restoring menstrual function. (The choice and control of hormonal treatment is carried out only by the attending physician!). Successful treatment to achieve ovulation and restore the ability to fertilize is associated with the risk of developing pregnancy. In this case, in order to prevent unplanned pregnancy, it is recommended to give preference to non-hormonal methods of contraception. The drug of choice may be Pharmatex, the pharmacological properties of which are provided by benzalkonium chloride: it has a powerful spermicidal effect, that is, it inactivates sperm and thereby prevents fertilization.

Pharmatex: reviews of the action

Pharmatex, when introduced into the vagina (in any dosage form), covers the vaginal mucosa and forms a continuous film on it. After entering the vagina, sperm die under its influence: the flagella are separated from the head and they can no longer move. Does not penetrate into the blood, breast milk - Pharmatex has an exclusively local effect, and not only contraceptive...

Pharmatex: reviews on preventing the spread of STIs

Pharmatex is also an additional prophylaxis against certain sexually transmitted infections. Benzalkonium chloride has a detrimental effect on the causative agents of certain bacteria and viruses: it neutralizes the activity of the causative agents of gonorrhea, chlamydia, and trichomoniasis. It also suppresses the activity of herpes viruses type 2 and Staphylococcus aureus. At the same time, the active substance of Pharmatex does not disrupt the natural microflora of the vagina and does not in any way affect hormonal relationships.

Pharmatex: reviews of forms and modes of application

Pharmatex is available in different forms, taking into account the individual needs of a woman.

Pharmatex (benzalkonium chloride 50% aqueous solution) is a vaginal contraceptive with a spermicidal effect. It has high spermicidal and disinfectant activity, as well as ease of use. Once in the vagina, benzalkonium chloride combines with the mucous membrane, covering it with a continuous protective film. It only takes a few seconds to immobilize and destroy the sperm. The spermicidal effect of benzalkonium chloride is four times greater than that of nonoxynol-9. In addition, this substance is an antiseptic and exhibits bactericidal activity against microorganisms that transmit sexually transmitted infections. The drug has no effect on saprophytic vaginal microflora. Does not have a systemic effect. Non-toxic, because does not penetrate into the blood. Quickly and irreversibly destroys sperm, separating the head from the flagellum. The unidirectional movement of benzalkonium chloride molecules ensures the integrity of the protective film covering the mucous membrane. The mucus produced by the cervix is ​​transparent and has a viscous and viscous consistency. Benzalkonium chloride makes it a thick, jelly-like substance that acts as a natural barrier to sperm entering the uterus. After 10 seconds from the moment of instillation of the drug into the vagina, it is impossible to detect a single viable sperm. The drug acts in the same way on bacteria and viruses: it breaks their membranes and causes cell lysis. Benzalkonium chloride is active against staphylococci, streptococci, coliform bacteria, enterobacteria, chlamydia, gardnerella, neisseria, treponema, trichomonas, herpes simplex virus, HIV, etc.

d. Weakly active or inactive against candida, Haemophilus influenzae, and mycoplasmas. It has no effect on normal microflora. The drug does not penetrate the uterine cavity, does not pass through the vaginal epithelium, and does not have a teratogenic effect, which is confirmed by many clinical trials (a total of 18 studies were conducted in Western Europe, Canada and the USA). The active component of the drug is easily removed from the vagina by regular rinsing and along with urine and other physiological secretions. Pharmatex can be used as a priority contraceptive:

If taking oral contraceptives or using an intrauterine device is contraindicated for some reason;

In the period after the birth of the child;

During breastfeeding (since the drug does not pass into breast milk and does not have systemic effects);

In teenagers;

With rare sexual intercourse, when there is no need for regular contraception using oral contraceptives;

In women over 40 years of age;

With an increased risk of contracting sexually transmitted infections.

Available in the form of vaginal capsules, tablets, suppositories and cream. The effectiveness of the contraceptive effect of Farmatex depends on the implementation of the recommendations set out in the instructions for use.

Pharmacology

Vaginal contraceptive. The spermicidal effect is due to the ability of the drug to destroy sperm membranes (first flagella, then heads), which leads to the impossibility of fertilization of an egg by damaged sperm.

The effect develops 10 minutes after insertion into the vagina.

In vitro, the drug is active against Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Herpes simplex type 2, Staphylococcus aureus.

Weakly active against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.

Not active against Mycoplasma spp.

Does not affect the normal microflora of the vagina (including Doderlein's bacillus) and the hormonal cycle.

Pharmacokinetics

Benzalkonium chloride is not absorbed by the vaginal mucosa. It can be removed by simple rinsing with water and normal physiological secretions.

Release form

Vaginal capsules are soft, translucent, light yellow, oval in shape; the contents of the capsules are an emulsion from white to white with a yellowish tint; slight separation of the capsule contents is possible.

Excipients: dimethicone 1000 - 1042.2 mg, colloidal silicon dioxide - 90 mg, hyprolose - 105 mg, macrogol-7-glyceryl cocoate - 150 mg, macrogol 400 - 75 mg.

Shell composition: gelatin - 385.25 mg, glycerol - 189.75 mg.

6 pcs. - blisters (1) - cardboard packs.
6 pcs. - blisters (2) - cardboard packs.

Dosage

Vaginal capsules. Lying on your back, the capsule is inserted deep into the vagina no later than 10 minutes before sexual intercourse. The duration of action of the drug is 4 hours. Be sure to administer a new capsule before each repeated sexual intercourse. 1 capsule is designed for one sexual act.

Vaginal tablets. Lying on your back, the tablet is inserted deep into the vagina no later than 10 minutes before sexual intercourse. The duration of action of the drug is 3 hours. Be sure to administer a new tablet before each repeated sexual intercourse. 1 tablet is designed for one sexual act.

Vaginal suppositories. Lying on your back, the suppository is inserted deep into the vagina no later than 5 minutes before sexual intercourse. The duration of action of the drug is 4 hours. Be sure to introduce a new suppository before each repeated sexual intercourse.

Before administering the vaginal cream, you should attach the dispenser to the tube instead of the cap. Gently squeeze out the contents of the tube until the dispenser is filled (until the piston stops) so that no air bubbles form. Disconnect the dispenser from the tube. Close the tube with a lid. Lying on your back, insert the cream deep into the vagina using a dispenser, slowly pressing the plunger. Duration of action - 10 hours. Be sure to administer a new dose of cream before each repeated sexual intercourse. 1 dose (5 g of cream) is designed for one sexual act.

Overdose

No cases of overdose have been reported.

Interaction

Concomitant use with medications administered vaginally is not recommended. Any drug introduced into the vagina can inactivate the local spermicidal effect of Pharmatex.

Iodine solutions (including 0.1% iodonate solution) inactivate the drug.

Soap and solutions containing it can reduce the spermicidal effect of the drug. You should not irrigate the vagina before and after sexual intercourse, because soap, even traces of it, destroys the active substance.

Side effects

Allergic reactions: contact dermatitis, itching and burning in the vagina and/or penis of the partner, painful urination. If they occur, stop using Pharmatex.

Indications

Local contraception for women of reproductive age, including:

• if there are contraindications to the use of oral contraceptives or intrauterine contraception;
• in the postpartum period;
• during lactation;
• after termination of pregnancy;
• during menopause;
• with irregular sexual intercourse;
• if you miss or are late in taking regularly used oral contraceptives.

As an additional local contraception when using a vaginal diaphragm or IUD.

Contraindications

• vaginitis;
• ulceration and irritation of the mucous membrane of the vagina and cervix;
• hypersensitivity to the components of the drug.

Application features

Use during pregnancy and breastfeeding

The drug is a contraceptive and is not used during pregnancy. When pregnancy occurs during contraception with benzalkonium chloride, no effect on the course of pregnancy was detected.

Benzalkonium chloride is not excreted in breast milk; the drug can be used during lactation.

special instructions

The effectiveness of contraception is associated solely with strict adherence to the rules of its use:

• enter the capsule (tablet, suppository, cream) so that the selected dosage form penetrates as deeply as possible into the vagina, preferably in the supine position;
• wait for the complete dissolution of the capsule or tablet in the vagina for at least 10 minutes, the suppository for at least 5 minutes, so that the active substance is completely released;
• be sure to introduce a new capsule (tablet, dose of cream, suppository) before each repeated sexual intercourse;
• it is forbidden to use soap for the toilet of the genital organs 2 hours before intercourse and within 2 hours after intercourse, because. soap, even in residual quantities, destroys the active ingredient of Farmatex;
• immediately after intercourse, the external toilet of the genital organs is possible only with clean water or with the help of a foaming agent Pharmatex, which does not contain soap, which includes benzalkonium chloride; vaginal irrigation is carried out 2 hours after sexual intercourse;
• with Pharmatex introduced into the vagina, you can not take baths, swim in the sea, pool and reservoirs because of the danger of reducing the subsequent contraceptive effect;
• since Pharmatex contains benzalkonium chloride, it is necessary to interrupt its use if any vaginal diseases occur or their exacerbation occurs;
• in the event that it becomes necessary to treat diseases of the vagina and / or prescribe any other drug vaginally, it is necessary to wait until the end of treatment before resuming (starting) contraception with Pharmatex.

Impact on the ability to drive vehicles and operate machinery

There is no evidence of a negative effect of the drug on the ability to drive vehicles and other mechanisms.

Instructions for use:

Pharmatex is a vaginal contraceptive with spermicidal action.

pharmachologic effect

The active ingredient of Pharmatex, being a spermicide and an antiseptic at the same time, destroys the membranes of spermatozoa, providing a contraceptive effect.

The use of Pharmatex according to the instructions significantly reduces the risk of pregnancy, but does not completely eliminate it. However, its effectiveness largely depends on the correct application.

According to the instructions, the active ingredient of Pharmatex is active against many pathogens that can cause a number of sexually transmitted diseases. To a greater extent, this applies to HIV, Chlamydia spp., Neisseria gonorrhoeae, Staphylococcus aureus, Trichomonas vaginalis and Herpes simplex type 2.

Pharmatex is weakly active against Haemophilus ducreyi, Candida albicans, Gardnerella vaginalis and Treponema pallidum and does not show activity against Mycoplasma spp.

Pharmatex has no effect on the saprophytic vaginal microflora (including the Doderlein bacillus).

The active component of Pharmatex, being absorbed only on the surface of the vaginal walls, is not absorbed by the mucous membrane, and after use is excreted with physiological secretions or can be eliminated by rinsing with water.

Pharmatex release form

Pharmatex is a drug for vaginal use, the main active component of which is benzalkonium chloride. Pharmatex is available in the form:

• Cylindrical vaginal tampons soaked in an oily white cream with a lavender scent;
• Homogeneous white 1.2% cream with lavender scent;
• Soft oval vaginal capsules of light yellow color, containing the active substance in the form of a yellowish emulsion;
• Round white vaginal tablets;
• White cylindrical vaginal suppositories with a cone-shaped end.

Pharmatex's analogues

Analogues of Farmatex containing the same active ingredient include the following drugs: Benatex, Contratex, Farmaginex, Ginekotex, Erotex in the form of gel, suppositories, tablets and cream for vaginal use.

Pharmatex analogues according to their mode of action are also produced. These include Contraceptin T, Nonoxynol, Sterilin and NuvaRing.

Indications for use of Pharmatex

According to the instructions, Farmatex can be used for local contraception by any woman of reproductive age if she has no contraindications.

Pharmatex, according to reviews, is effective in cases of skipping or being late in taking oral contraceptives if they are used continuously.

Also, the use of Pharmatex is shown:

• If there are contraindications (temporary or absolute) to the use of an intrauterine device or oral contraceptives;

• While breastfeeding;
• In the postpartum period;
• In the period that precedes menopause;
• After the termination of pregnancy;
• If necessary, protection from pregnancy, which is episodic in nature.

In addition, according to reviews, Pharmatex can be used as an additional local contraception when using an intrauterine device or vaginal diaphragm (especially if certain medications are taken during this period, for example, non-steroidal anti-inflammatory drugs).

Contraindications

The use of Pharmatex is contraindicated in:

• Ulceration and irritation of the mucous membrane of the vagina and uterus;
• Colpitis;
• Hypersensitivity to the components of the drug;
• If it is impossible to use Pharmatex correctly (usually in case of mental disorders).

How to use Pharmatex

Farmatex vaginal tablets should be inserted deep into the vagina while lying on your back. According to the instructions, the drug must be administered 10 minutes before sexual intercourse. When using Farmatex in tablet form, it should be taken into account that its duration of action is three hours. A new Pharmatex tablet should be administered before each sexual intercourse.

Pharmatex vaginal capsules and suppositories are used in the same way as tablets. The duration of action is four hours.

Pharmatex vaginal tampons are inserted until contact with the cervix. The protective effect of using Pharmatex tampons occurs immediately and continues throughout the day, regardless of the number of sexual acts. After the last sexual intercourse, you can remove the tampon from the vagina two hours later, but no later than one day after insertion.

Pharmatex cream is administered using a dosing device installed at the end of the tube. After it is completely filled (until the piston stops or to the ring-shaped mark), the cream is administered before sexual intercourse, pressing slowly on the piston. The protective effect of Pharmatex, lasting ten hours, begins immediately after administration. The procedure is repeated before each new sexual intercourse.

The frequency of use of Pharmatex according to the instructions is limited by individual tolerance of the active component. This contraceptive can be used during pregnancy and lactation.

There are no data on overdose with Pharmatex.

Pharmatex can be used simultaneously with an IUD or vaginal diaphragm.

Since the effectiveness of contraception provided by Pharmatex is associated with strict adherence to the rules of its use, you must adhere to the following instructions:

• Pharmatex (tablet, cream, suppository, capsule) should be used before each sexual intercourse;
• It is necessary to administer the drug in any of the dosage forms as deeply as possible into the vagina (preferably in a lying position);
• You should wait until the suppository (5 minutes), capsule or tablet (10 minutes) dissolves for complete release of the active substance;
• External toilet of the genital organs after sexual intercourse can only be done with clean water. You should not use soap two hours before sexual intercourse and for at least two hours after it, since even residual amounts of soap can destroy the active component of Farmatex;
• You should not take baths with the drug in any dosage form inserted into the vagina, nor should you swim in the pool, sea or reservoirs.

Drug interactions

Since any drug administered topically into the vagina can reduce and even completely inactivate the spermicidal effect of Farmatex, the drug should not be used with other drugs used vaginally.

In addition, when using Farmatex, it should be taken into account that its properties are destroyed under the influence of soap and even its traces.

Side effects

According to reviews, Pharmatex can cause allergic reactions (in the form of burning, itching or contact dermatitis), if they occur, use of the product must be discontinued.

Storage conditions for Pharmatex

Pharmatex belongs to a number of contraceptives that can be dispensed from pharmacies without a prescription. The shelf life of vaginal capsules and tablets is 2 years, suppositories, creams and tampons are 3 years (subject to temperature conditions up to 25°C).

Instructions for using the drug Farmatex in vaginal capsules, vaginal tablets, vaginal suppositories, vaginal tampons and vaginal cream

Pharmatex is a spermicidal contraceptive drug intended for topical use. Pharmatex has a pronounced local contraceptive effect, which consists in the destruction of sperm (spermicidal effect), as well as antimicrobial, antifungal and antiviral effects, which protect against some sexually transmitted infections. Pharmatex is available in the form of vaginal capsules, vaginal tablets, vaginal suppositories, vaginal tampons and vaginal cream.

How does Pharmatex work?

The spermicidal effect of the drug is due to the fact that Pharmatex damages the membranes of spermatozoa and causes their destruction, which in turn makes it impossible for the fertilization process. The use of the drug significantly reduces the risk of pregnancy, but does not eliminate it completely. The destructive effect of Pharmatex extends not only to spermatozoa, but also to microbes, pathogens of sexually transmitted diseases (STDs).

Laboratory studies have shown that Pharmatex is active against pathogens of gonorrhea (gonococcus), chlamydia (chlamydia), herpes virus (type 2) and HIV / AIDS, trichomoniasis (Trichomonas vaginalis). At the same time, Pharmatex has practically no effect on the pathogens of urogenital mycoplasmosis (mycoplasma) and has little effect on the pathogens of gardnerellosis (Gardnerella vaginali), thrush (Candida albicans), syphilis (Treponema pallidum).

Pharmatex does not affect the normal microflora of the vagina (including the Doderlein stick) and does not cause bacterial vaginosis. Also, the use of Pharmatex does not have any effect on the menstrual cycle.

In what cases should Pharmatex be used?

The main indication for the use of Pharmatex is local contraception for any woman of reproductive age who has no contraindications to this. Due to the relatively low reliability and some side effects, the use of Pharmatex is most often indicated in the following situations:

• the presence of temporary or absolute contraindications to the use of oral contraceptives or an intrauterine device;
• in the period after childbirth and during breastfeeding;
• after termination of pregnancy;
• in the period preceding menopause;
• if necessary, occasional birth control;
• with the constant use of oral contraceptives in case of skipping or being late in taking the pill.

Dosage and method of use of the drug Farmatex

Pharmatex is available in the form of vaginal capsules, vaginal tablets, vaginal suppositories, vaginal tampons and vaginal cream.
Method of administration: all Pharmatex drugs are injected deep into the vagina. The maximum effectiveness of Pharmatex is observed in cases where it comes into contact with the cervix.

Pharmatex vaginal capsules and tablets

Lying on the back, 1 tablet or 1 capsule is injected deep into the vagina, no later than 10 minutes before sexual intercourse. Duration of action is 4 hours for a capsule or 3 hours for a tablet. Before each subsequent sexual intercourse, a new tablet or capsule should be introduced. 1 tablet or 1 capsule is designed for one sexual act.

Pharmatex vaginal suppositories

Lying on the back, the suppository is inserted deep into the vagina no later than 5 minutes before sexual intercourse. The duration of the candle is 4 hours. Before each sexual intercourse, a new candle should be introduced. 1 candle is designed for 1 sexual intercourse.

Pharmatex vaginal tampons

First, the tampon is removed from the protective packaging, then, spreading the labia with one hand, the other hand inserts the tampon into the vagina and moves it deep into the vagina to the cervix. The protective effect develops immediately and lasts 24 hours (if you have repeated sexual intercourse within 1 day, changing the tampon is not required). You can remove the tampon 2 hours after the last sexual intercourse, but no later than 24 hours after its insertion.

Vaginal cream

The cream is injected into the vagina using a dispenser-applicator, preferably in a lying position. The protective effect of the drug begins immediately and lasts for at least 10 hours. Before each repeated sexual intercourse, be sure to administer a new portion of the cream. 1 serving of cream is designed for one sexual act.

Side effects when using the drug Farmatex

When using the drug according to indications in the recommended dosage, the risk of side effects is minimal. Sometimes allergic reactions may develop: burning, itching, contact dermatitis. If they occur, you should stop using Pharmatex.

In what cases should Farmatex not be used?

Pharmatex cannot be used in the following cases:

• colpitis, bacterial vaginosis
• ulceration and irritation of the mucous membrane of the vagina and uterus
• hypersensitivity to the components of the drug.

Use of the drug Farmatex during pregnancy and breastfeeding

Pharmatex does not have a harmful effect on pregnancy and the fetus, is not excreted in breast milk, and therefore can be used during lactation and during pregnancy.

Special instructions for using the drug Farmatex

The use of the drug Farmatex significantly reduces the risk of pregnancy, but does not eliminate it completely. The effectiveness of contraception is associated solely with strict adherence to the rules of its use:

• Pharmatex should be used systematically before each sexual intercourse;
• The capsule (tablet, suppository, tampon, cream) should be inserted so that the selected dosage form penetrates as deeply as possible into the vagina. It is preferable to administer Pharmatex in the supine position;
• You should wait for the capsule or tablet to completely dissolve in the vagina (at least 10 minutes), the suppository (at least 5 minutes) so that the active substance is completely released;
• It is prohibited to use soap for toileting the genitals 2 hours before sexual intercourse and for 2 hours after sexual intercourse, since soap, even in residual quantities, destroys the active ingredient of Pharmatex;
• Immediately after sexual intercourse, only the external toilet of the genital organs should be performed with clean water only;
• While using Farmatex, you should not take baths, swim in the sea, pools or ponds due to the risk of reducing its contraceptive effect;
• It is necessary to interrupt the use of Pharmatex if any vaginal infections occur or if they worsen;
• If there is a need to treat vaginal diseases and/or prescribe any other vaginal medicinal product, you must wait until the end of treatment before resuming or starting contraception with Pharmatex.

Interaction of the drug Pharmatex with other drugs