Zopiclone trade. Instructions for use zopiclone

1000 pcs. - polyethylene bottles (1) - cardboard packs.
5 kg - plastic bags (1) - plastic containers.
8 kg - plastic bags (1) - plastic containers.
10 kg - plastic bags (1) - plastic containers.
15 kg - plastic bags (1) - plastic containers.
20 kg - plastic bags (1) - plastic containers.

pharmachologic effect

A hypnotic drug from the group of cyclopyrrolone derivatives. "Non-benzodiazepine" benzodiazepine receptor agonist. It also has sedative, anxiolytic, central muscle-relaxing, anticonvulsant and amnesic properties. Like benzodiazepine derivatives, zopiclone enhances GABAergic processes in the brain by interacting with benzodiazepine receptors, as a result of which the sensitivity of GABA receptors to the mediator increases. However, zopiclone appears to interact with other benzodiazepine receptor sites than benzodiazepines.

Zopiclone reduces the time to fall asleep, reduces the number of nocturnal awakenings, and increases the total duration of sleep. Practically does not affect the structure of sleep, does not significantly reduce the amount of REM sleep. The phenomena of the consequences upon awakening are absent or expressed little. Repeated doses of zopiclone are not accompanied by cumulation.

Pharmacokinetics

Rapidly and completely absorbed from the gastrointestinal tract. C max is achieved in 1-3 hours. It easily passes through histohematic barriers, including the BBB, and spreads through organs and tissues, incl. brain. T 1/2 - 5.5-6 h; does not accumulate.

Indications

Sleep disorders (difficulty falling asleep, frequent nocturnal awakenings, early awakening), transient, situational and chronic insomnia; sleep disturbances in mental disorders, bronchial asthma with nocturnal attacks (in combination with a single daily dose).

Contraindications

Severe respiratory failure, pregnancy, lactation (breastfeeding), children and adolescents under 15 years of age, hypersensitivity to zopiclone.

Dosage

The average therapeutic dose is 7.5 mg orally at night, in severe cases the dose can be increased to 15 mg. In elderly patients, as well as in violation of liver function, 3.75 mg is used.

Side effects

From the digestive system: feeling of a bitter or metallic taste in the mouth, dry mouth, nausea,.

From the side of the central nervous system: dizziness, headache, drowsiness, confusion, anterograde amnesia, hallucinations, nightmares.

Dermatological reactions: skin rash.

drug interaction

With simultaneous use reduces the concentration of trimipramine in and its effect.

Zopiclone enhances the effect of drugs that depress the central nervous system (including ethanol).

Human sleep disturbance is considered a worldwide problem. The fatigue accumulated during the day literally knocks you off your feet. The person goes to bed and cannot fall asleep until morning. A large number of people suffer from insomnia, and the age in its occurrence practically does not matter. Adolescents and the elderly are susceptible to this disorder, even small children are not immune from it. Short-term manifestations of insomnia do not harm the body. If sleep disturbance becomes chronic, the quality of life and human health suffer. That is why such a disorder must be dealt with in a timely manner. One drug widely used for insomnia is Zopiclone. Instructions for use characterizes it as excellent

Composition and form of release

The drug is available in the form of a powder for the preparation of dosage forms. The substance is packaged in two-layer polyethylene bags. The consumer can purchase the drug from a pharmacy in the form of tablets. Its active component is the synthetic substance zopiclone. Instructions for use informs that each tablet of the drug contains 7.5 mg of the active ingredient. The pills are packaged in blisters.

Pharmacological properties

Zopiclone is a third-generation hypnotic tranquilizer. Its main difference from other drugs is the ability to maintain a full-fledged sleep structure. The primary purpose of "Zopiklon" is the implementation of a hypnotic effect. Against the background of taking the medicine, the time to fall asleep is reduced, the quality of rest is significantly improved. In addition to sleeping pills, the medication has a relaxing and calming effect on the entire body.

Indications for use

What does the instructions for use say about Zopiclone? According to the annotation, the drug promotes rapid falling asleep. It supports quality sleep at night, providing its phase composition. The drug does not cause post-somnic disorders. This means that the next day there is no feeling of weakness or malaise.

Given the described properties, Zopiclone is used for:

• sleep disorders (frequent awakenings, difficulty falling asleep);
• bronchial asthma with nocturnal awakenings;
• situational or chronic insomnia.

After taking the pill, sleep occurs within 30 minutes and lasts about 7-8 hours.

Method of application and dosing regimen

The drug "Zopiklon" instructions for use recommends using it orally. The dosage regimen is determined by the doctor. As a rule, patients with insomnia are prescribed one tablet at night. If necessary, the dosage can be increased to two pills.

Tablets can not be chewed, it is better to drink water. The action of the drug begins 20-30 minutes after ingestion. The duration of the course of therapy should not exceed more than four weeks. Otherwise develops to cope with which is very difficult. If after one month sleep does not normalize, it is necessary to consult a doctor again to adjust the treatment regimen.

Contraindications and side effects

In what cases should treatment with Zopiclone be discontinued? The instruction does not recommend taking pills:

• pregnant and lactating women;
• children under 18;
• patients with respiratory failure.

With caution, the medication is prescribed to people suffering from sleep apnea, acute liver or kidney failure.

Instructions for the drug prohibits its use during pregnancy. The active active substance can provoke various disorders of the fetal central nervous system. In case of urgent need, the use of Zopiclone in the second trimester is allowed, but only with the permission of the doctor. During lactation, medication is possible provided that breastfeeding is refused for the entire duration of treatment.

Subject to the dosing regimen "Zopiklon", the drug analogues are well tolerated by patients. In rare cases, excessive drowsiness and fatigue, dizziness and confusion may occur.

During treatment with Zopiclone, you should stop drinking alcohol and drugs that have alcohol in their composition. Cancellation of the drug should be carried out gradually. The risk of drug dependence, provided that the medication is used for less than four weeks in a row, is minimal.

The cost of funds

What is the price of Zopiclone? The total cost of the drug depends on the mark-up of the pharmacy chain and the region of its location. On average, the price of one package is from 550 to 1000 rubles.

Drug analogues

Finding a good sleeping pill today is not difficult. Modern pharmaceutical companies offer many synonyms for Zopiclone. Analogues differ only in cost and components included in the composition.

The following drugs have a similar pharmacological effect on the body:

• "Hypnogen".
• "Andante".
• "Sanwal".
• "Oniria".
• "Snovitel".

Common synonyms that include a similar active ingredient include: Imovan, Somnol, Thorson.

pharmachologic effect

Pharmacokinetics

Rapidly and completely absorbed from the gastrointestinal tract. C max is achieved in 1-3 hours. It easily passes through histohematic barriers, including the BBB, and spreads through organs and tissues, incl. brain. T 1/2 - 5.5-6 h; does not accumulate.

Dosage

The average therapeutic dose is 7.5 mg orally at night, in cases of severe insomnia, the dose can be increased to 15 mg. In elderly patients, as well as in violation of liver function, 3.75 mg is used.

drug interaction

With simultaneous use reduces the concentration of trimipramine in plasma and its effect.

Zopiclone enhances the effect of drugs that depress the central nervous system (including ethanol).

Pregnancy and lactation

Zopiclone is contraindicated for use during pregnancy and lactation (breastfeeding).

Side effects

From the digestive system: feeling of a bitter or metallic taste in the mouth, dry mouth, nausea, vomiting.

From the side of the central nervous system: dizziness, headache, drowsiness, confusion, anterograde amnesia, hallucinations, nightmares.

Dermatological reactions: skin rash.

Indications

Sleep disorders (difficulty falling asleep, frequent nocturnal awakenings, early awakening), transient, situational and chronic insomnia; sleep disturbances in mental disorders, bronchial asthma with nocturnal attacks (in combination with a single daily dose of theophylline).

Contraindications

Severe respiratory failure, pregnancy, lactation (breastfeeding), children and adolescents under 15 years of age, hypersensitivity to zopiclone.

special instructions

Be wary appoint in severe liver failure.

The risk of drug dependence is minimal if the duration of zopiclone use does not exceed 4 weeks. However, the potential danger of developing dependence on zopiclone exists.

During the period of treatment, alcohol should be excluded.

Influence on the ability to drive vehicles and control mechanisms

The next day after taking the drug, you should drive a car and work with mechanisms with caution.

Medicines containing ZOPICLONE (ZOPICLONE)

TORSON (TORSON) tab., coating. film shell., 3.75 mg: 10 or 20 pcs.
. SLIPVELL (SLIPVELL) tab. 7.5 mg: 10 or 20 pcs.
. PIKLODORM ® (PICLODORM) tab. shell, 7.5 mg: 10 or 20 pcs.
. MILOVAN (MILOVAN) tab. shell, 3.75 mg: 5, 10, 20 or 30 pcs.
. ZOLINOX (ZOLINOX) tab., coating film coated, 7.5 mg: 10 or 100 pcs.
. TORSON (TORSON) tab., coating. film shell., 7.5 mg: 10 and 20 pcs.
. ZOPICLONE (ZOPICLONE) tab. 7.5 mg: 5, 10, 15 or 20 pcs.
. SOMNOL ® (SOMNOL) tab. shell, 7.5 mg: 10 or 20 pcs.
. ZOPICLONE 7.5-SL (ZOPICLONE 7.5-SL) tab. 7.5 mg: 10 or 20 pcs.
. PIKLODORM ® (PICLODORM) tab. shell, 7.5 mg: 10 or 20 pcs.
. IMOVANE ® (IMOVANE ®) tab., coated. film-coated, 7.5 mg: 20 pcs.
. RELAXON (RELAXON) tab., coated. film shell., 7.5 mg: 5, 10, 15, 20, 30 or 40 pcs.
. ZOPICLONE (ZOPICLONE) tab. shell, 7.5 mg: 1000 pieces, 5 kg, 8 kg, 10 kg or 20 kg
. MILOVAN (MILOVAN) tab. shell, 7.5 mg: 5, 10, 20 or 30 pcs.

ZOPICLON - description and instructions provided by the reference book of medicines Vidal.

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Analogues (generics, synonyms)

There are no other names

Recipe (international)

Rp: Zopiclone 0.0075
D.t.d: N 5 in tab.
S: One tablet at bedtime

pharmachologic effect

A hypnotic drug from the group of cyclopyrrolones, structurally different from benzodiazepines and barbiturates. It has a sedative, hypnotic effect, which is due to a high degree of affinity for binding sites on the GABA receptor complex in the central nervous system. Quickly induces sleep without reducing the phase of REM sleep in its structure, and then maintains sleep while maintaining the normal phase composition. It does not cause post-somnic disorders: there are no feelings of fatigue and drowsiness the next morning. Sleep comes within 30 minutes and lasts 6-8 hours. Reduces headaches. In patients with nocturnal attacks of bronchial asthma, in combination with drugs of the methylxanthine series (theophylline), it reduces asthma attacks in the early morning hours, reduces their intensity and duration.

Mode of application

For adults: Inside, 7.5 mg, 30-40 minutes before the intended sleep, if necessary, up to 15 mg (maximum dose). The initial dose for the elderly and the maximum recommended dose for liver failure is 3.75 mg. Duration of continuous use - no more than 1 month.

Indications

Sleep disorders: difficulty falling asleep, nocturnal awakenings, early awakening; transient, situational and chronic insomnia; sleep disturbances in mental disorders, bronchial asthma with nocturnal attacks (in combination with a single daily dose of theophylline).

Contraindications

Hypersensitivity, severe respiratory failure, myasthenia gravis, severe liver failure, sleep apnea syndrome, age up to 18 years, pregnancy, lactation. With caution. Liver failure.

Side effects

"Metallic" taste in the mouth, nausea, vomiting, mental disorders (irritability, confusion, depressed mood), allergic reactions (urticaria, rash). Upon awakening - drowsiness, dizziness, impaired coordination of movements, sometimes depressive states, aggressiveness, anterograde amnesia.

Release form

1 coated tablet contains zopiclone 7.5 mg and other excipients - lactose monohydrate, magnesium stearate, hypromellose, titanium dioxide, wheat starch, calcium dihydrogen phosphate, sodium carboxymethyl starch; in a blister pack 10 pcs., in a carton pack 1 or 2 packs.

ATTENTION!

The information on the page you are viewing was created for informational purposes only and does not promote self-treatment in any way. The resource is intended to familiarize healthcare professionals with additional information about certain medicines, thereby increasing their level of professionalism. The use of the drug Zopiclone"mandatory provides for a consultation with a specialist, as well as his recommendations on the method of application and dosage of the medicine you have chosen.