Treatment of various types of bacterial vaginitis in women is complicated by the fact that many drugs have contraindications. The problem is especially relevant during pregnancy and breastfeeding. Women of these categories have to carefully select medicines, one of which is the Geksikon-D or Geksikon-16 vaginal suppositories. We will give instructions for use in gynecology and tell you about the features of therapy with this remedy.

Description and composition

Hexicon is a torpedo-shaped suppository of white color, sometimes with a pale yellow or marble tint. The suppository contains hexidine bigluconate - a strong antiseptic with low absorption into the systemic circulation. Due to this, Geksikon has very minor contraindications.

The auxiliary components are polyethylene oxide. This substance does not have a particular effect on the woman's body, does not treat gynecological diseases, but helps to maintain the shape of the suppositories and provides the best effect of hexidine.

Application in gynecology

Hexicon is an antiseptic drug used exclusively intravaginally. The active substance of the drug greatly weakens the functions of many pathogens, including:

• triponem;
• chlamydia;
• ureaplasma;
• gardnerell;
• trichomonas.

Geksikon also helps to fight human papillomavirus types 1 and 2 (HPV-1 and HPV-2). At the same time, the drug does not have a negative effect on lactobacilli, therefore it can be used in the treatment of vaginitis and vaginosis of various etiologies.

In addition to the above diseases, Hexicon is used in the following cases:

• for the prevention of STDs;
• before intrauterine studies;
• before surgical treatment of gynecological diseases;
• during endometritis;
• with endocervicitis;
• in the treatment of thrush;
• in the treatment of cervical erosion.

Hexicon is well tolerated by the female body and almost never causes side effects. However, for women who are going to use these candles at home, it is better to consult a gynecologist.

Contraindications and side effects

The peculiarity of the drug is a small number of contraindications and side effects. The first includes hypersensitivity to the active substance and existing allergic reactions.

Occasionally, women turn to a gynecologist for side effects:

• itching;
• burning sensation;
• rashes on the pubis and genitals

Hexidine penetrates the mucous membrane in negligible doses, therefore, it does not have a noticeable effect on vital organs and systems. There have been no cases of overdose with suppositories.

Dosage and course of treatment

In most cases, the doctor adheres to the instructions for use, according to which the prophylactic dose is 1 suppository per day, the therapeutic dose is 1-2 suppositories. The duration of treatment in the second case is up to 10 days, only in rare cases this period is increased to 20 days.

However, sometimes doctors deviate from the manufacturer's prescriptions. This is due to the peculiarities of the course of the disease and the health conditions of the sick woman.

Features of treatment with candles Geksikon

Vaginal suppositories Geksikon D have a local effect, therefore, they have few features in use. It has been established that the active substance (AR) is rapidly excreted from the body, does not enter the systemic circulation, and therefore does not enter breast milk. The likelihood of DV penetration through the placenta and the negative impact on fetal development are also minimal.

When treating with suppositories, the following points should be considered:

1. During pregnancy, the risk of allergy to Hexicon increases, it is good to consult an allergist before the course.
2. It is undesirable to start the course 2-3 days before the onset of menstruation - during menstruation, the effectiveness of suppositories decreases. The optimal period is the middle of the cycle.
3. During treatment, it is better to wash with baby soap. Many cosmetics include SLS and SLES components. They affect the foaming of products, but are incompatible with Hexicon.
4. Douching with any solution, including soap, is strictly prohibited.
5. Sexual intercourse during treatment with Geksikon is not recommended.
6. Hexicon reduces the effectiveness of latex condoms.
7. The active ingredient of the suppository is not combined with iodine and preparations in which it is present.

Also, during therapy, it should be borne in mind that purulent discharge, as well as leucorrhoea or blood, reduce the effectiveness of suppositories. If necessary, the doctor can prescribe a general anti-inflammatory drug or take steps to remove barriers to adequate treatment.

Candle analogs

The Geksikon candles have analogues in composition - an alcohol solution of Chlorhexidine and Amident solution. But the use of these compounds in gynecology is very limited: for inflammatory processes in the cervix, it is better to use suppositories.

As for suppositories, similar actions have:

• Iodovidone;
• Betadine;
• McMiror;
• Iodoxide;
• Povidone-Iodine;
• Lactoginal capsules.

At the same time, preparations with iodine are contraindicated during pregnancy, and all of these drugs have various side effects. Therefore, if the question about analogues is asked in order to find a cheaper drug, it is better not to save money. Especially if the treatment is prescribed to a pregnant or lactating woman.

Price and terms of sale

Geksikon-D and Geksikon-16 are sold in Russian pharmacies without a prescription. The cost of the drug depends on the country, region of residence and retail network. Some pharmacies can buy one suppository, which is beneficial for short courses. You can compare prices in Russia and Ukraine using the table.

This drug is considered the most effective in preventing infections and diseases that are sexually transmitted. It is produced in the form of suppositories or suppositories specifically for vaginal administration. This drug has some recommendations for use, as well as a number of contraindications from the point of view of gynecology. Let's talk about this in more detail.

Geksikon candles indications for use - from what help?

Note that this medication assumes only local use, and does not require a special prescription or doctor's prescription. Its main pharmacological properties are the treatment of most of the most common infections in gynecology, such as chlamydia, a variety of vaginosis, and ureaplasmosis. It also helps in terms of prevention - i.e. the drug can be injected into the vagina even before intercourse. In this case, the probability of transmission of infection will decrease by 75%, so if you are worried about your own health, but do not want to resort to sex protected with contraceptives, remember about prophylactic candles.

Contraindications

It is not recommended to use it for those who suffer from any dermitis pitchfork, have an allergic reaction to any components that make up the composition (instructions for use will be described below). The vaginal drug is also not recommended to be used simultaneously with the application of iodine - alcohol weakens the effect of the drug, and sometimes it can cause an inflammatory process of the mucous layers of the vagina.

Hexicon composition

One unit contains 0.016 g of the main active agent - chlorhexidine bigluconate. It is this that helps against the most common infections in gynecology. The rest of the mass is made up of a polyethylene oxide base. The total weight of one unit is indicated as 3 g. By its nature, the described agent is an antiseptic.

Geksikon suppositories vaginal instructions for use

Here much depends on the purposes of use according to the instructions: if this is a treatment, then the agent must be administered in the morning and evening in the amount of 1 unit. Helps after 7-10 days.

In the case of prophylaxis, the instructions for use are as follows: within 5 days in the morning and in the evening, 1 piece.

In all cases, the candle should be inserted as deeply into the vagina as possible, so a position should be chosen that provides maximum penetration.

Important:

Suppositories Geksikon instructions for use in gynecology recommends using no more than 2 times a day, regardless of whether it is treatment or prevention. Only the duration of the drug intake varies, but its amount during the day.

Hexicon candles for menstruation

This particular case is not included in the number of contraindications, therefore, if menstruation occurs during the course, treatment / prevention should not be interrupted. This is noted in the instructions for use itself.

Instructions for use during pregnancy

During pregnancy, Hexicon is also applied no more than 1-2 times a day, but already for about 7-20 days. In this case, be sure to consult with your doctor before use, because application can cause severe side effects.

Geksikon suppositories for burning, itching, infections and inflammation how to use - instructions

It should be inserted as deep as possible into the vagina. But if after using it there is pain or itching, you should stop the use, because certain ingredients are more likely to cause an allergic reaction. There should not be any unpleasant / painful sensations.

Geksikon vaginal suppositories in early pregnancy

Hexicon candles from thrush

Thrush is not one of the infections and diseases that can be sexually transmitted. Therefore, it is worth looking for other means to use.

Analogs of geksikon

The main analogue is Pimafucin. But they also have a number of contraindications.

Geksikon (INN chlorhexidine bigluconate) is a local antiseptic drug for use in gynecological practice from the Russian pharmaceutical company Nizhpharm. Used to prevent infections of the genitourinary tract in women. The share of patients of this profile accounts for about 60% of all visits to the gynecologist. Inflammatory infections can lead to non-hormonal infertility, ectopic pregnancy, miscarriages, and abnormalities in fetal development. Geksikon is an over-the-counter drug that is in wide demand today both as a means of prevention and as a tool for the effective treatment of sexually transmitted infections. The main pathogenic "residents" of the female genitourinary tract are Trichomonas, chlamydia, ureaplasma, mycoplasma, gonococcus. The relief of infectious processes in the genital tract is complicated today by the increased aggressiveness of opportunistic microflora, the widespread occurrence of the phenomenon of drug resistance to antimicrobial drugs, a tendency to a decrease in the immune status in the general population, and inopportune and incorrect diagnosis. The antimicrobial and antiseptic drug Geksikon is distinguished by the speed and breadth of its therapeutic action, in the sphere of which bacteria such as Trihomonas vaginalis, Ureaplasma spp., Chlamidia spp., Treponema pallidum, Neisseria gonorrhoeae fall. It is produced in dosage forms for local use: vaginal tablets, suppositories, solutions. The advantage of local treatment of genital infections is minimization of the risk of developing undesirable side reactions (the vast majority of which are of a systemic nature), ease of use, the possibility of using patients with extragenital (non-sexual) pathology, primarily with a localized infectious and inflammatory process (for example, with acute vaginitis, cervicitis, vulvitis or chronic processes in the acute stage).

Hexicon can become a means of emergency prevention of sexually transmitted diseases immediately after unprotected intercourse (but no later than two hours after it). Geksikon has been well studied in several clinical studies conducted in Russia. So, in one of them, its effectiveness in the treatment of infectious vaginosis was confirmed for certain: 5-7 days of admission was enough to normalize the vaginal microflora. The effect of Hexadecone on the microbial biotope of the vagina in women of childbearing age with recurrent bacterial vaginosis was also studied. As a result, the antimicrobial activity of the drug in relation to aerobic and anaerobic microflora and its good therapeutic effect in patients with bacterial vaginosis were established. Chlorhexidine does not affect the functional activity of lactic acid bacteria. The drug retains its antimicrobial activity in the presence of biological fluids (blood, pus). As already noted, Geksikon has only local side effects in the form of rare allergies to chlorhexidine. Pregnancy and the period of breastfeeding are not contraindications to the use of the drug. Hygienic procedures of the external genital organs do not affect the activity and tolerance of Hexicon, since the drug is used intravaginally. To date, no cases of chlorhexidine overdose have been reported.

Pharmacology

Antiseptic drug, active against gram-positive and gram-negative bacteria (including Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis); protozoa (Trichomonas vaginalis); viruses (Herpes virus); yeast-like fungi of the genus Candida, dermatophytes (pathogens of favus (scab) microsporia, rubrophytosis, trichophytosis, epidermophytosis). Remains active (albeit somewhat reduced) in the presence of blood, pus.

Does not damage granulation and viable skin cells, does not inhibit marginal epithelization. Does not possess local irritating effect and allergenic properties.

Pharmacokinetics

Practically not absorbed from the digestive tract. After accidental ingestion, 300 mg Cmax is reached after 30 minutes and is 0.206 μg / L. It is excreted mainly through the intestines (90%), less than 1% is excreted by the kidneys.

When applied topically, it does not have the ability to be absorbed through the skin and mucous membranes.

Release form

Solution for external use 0.05% colorless, transparent or slightly opalescent, odorless.

Excipients: purified water.

10 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.
50 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.
70 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.
100 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.
150 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.
200 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.
250 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.
500 ml - polyethylene bottles (1) with a polymer nozzle - cardboard packs.

Dosage

Outwardly, locally.

Geksikon® solution is used in the form of irrigation, rinsing and applications - 5-10 ml of the solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times / day (on a tampon or by irrigation).

For the prevention of sexually transmitted infections, Geksikon ® is effective if it is applied no later than 2 hours after intercourse.

Using a nozzle, insert the contents of the bottle into the urethra for men (2-3 ml), women (1-2 ml) and into the vagina (5-10 ml) and hold for 2-3 minutes.

Treat the skin of the inner surfaces of the thighs, pubis, genitals with a solution. After the procedure, you should not urinate for two hours.

Complex treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml of Hexicon ® solution into the urethra 1-2 times / day, the course is 10 days. The procedures are prescribed every other day.

For stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 5-10 ml of the drug, 3-4 times / day.

Overdose

Due to low systemic absorption, overdose is unlikely. Cases of drug overdose are unknown.

Interaction

Pharmaceutically incompatible with detergents containing anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose), and soaps. The presence of soap can inactivate chlorhexidine; therefore, soap residues must be thoroughly washed off before using the drug.

Compatible with medicines containing a cationic group (benzalkonium chloride, cetrimonium bromide).

Ethanol enhances the effectiveness of the drug.

Side effects

Extremely rare: allergic reactions, itching that pass after discontinuation of the drug, dry skin, dermatitis, stickiness of the skin of the hands (within 3-5 minutes), photosensitivity.

In the treatment of gingivitis - staining of tooth enamel, tartar deposition, taste disturbance.

Indications

Prevention of sexually transmitted infections:

• chlamydia;
• ureaplasmosis;
• trichomoniasis;
• gonorrhea;
• syphilis;
• genital herpes.

Disinfection of purulent wounds, infected burn surfaces.

Treatment of infections of the skin and mucous membranes in surgery, obstetrics-gynecology, urology (urethritis, urethroprostatitis), dentistry (rinsing and irrigation - gingivitis, stomatitis, aphthae, periodontitis, alveolitis).

Contraindications

• hypersensitivity to drug components;
• dermatitis.

Application features

Application during pregnancy and lactation

Application is possible during pregnancy, lactation.

Application in children

With care: children's age.

special instructions

Avoid getting the drug inside the wound in patients with open traumatic brain injury, spinal cord injury, perforation of the tympanic membrane. If the solution gets on the mucous membranes of the eyes, they should be quickly and thoroughly rinsed with water.

The contact of hypochlorite bleaching agents on fabrics that have previously been in contact with drugs containing chlorhexidine can cause brown stains on them.

The bactericidal effect increases with an increase in the temperature of the solution.

At temperatures above 100 ° C, the drug is partially decomposed.

Influence on the ability to drive vehicles and use mechanisms

Publication date: 26-11-2019

How to use Geksikon suppositories for pancreatitis correctly?

Most antiseptics for the treatment of genitourinary diseases have many contraindications. Therefore, there is a risk of causing additional harm to health, even with the correct use of the medicine. One of the few drugs that has a quick therapeutic effect and practically no side effects is Geksikon.

Registration number and ATX

In the state register, the registration number of the Hexicon is P N001901 / 01.

In the International Classification of Medicines (ATC) the drug is assigned the code G01AX.

From what is appointed

In gynecology, suppositories are used to prevent the development of genital infections and venereal diseases.

In obstetric practice, the drug is often prescribed to women before:

• diagnostic measures;
• the installation of intrauterine contraceptives;
• surgical intervention;
• procedures that pose a potential risk of developing an infectious and inflammatory process.

Prescribed for the treatment of various forms of colpitis and bacterial vaginosis.

Hexicon is not intended for the treatment of candidiasis, but it can be recommended for a woman in combination with other medications for thrush.

Composition and pharmacological action

The suppository contains:

• chlorhexidine bigluconate (active ingredient);
• macrogol 1500 and 400.

Pharmacodynamics

An antiseptic drug that suppresses the activity of the simplest bacteria and viruses. Vaginal suppositories do not disrupt the functional activity of lactobacilli, even when used during menstruation or purulent vaginal discharge. Fungi, acid-resistant forms and bacterial spores are not sensitive to this drug.

Pharmacokinetics. Does not have a systemic effect. Absorption into the body is minimal.

How to light Geksikon candles

It is necessary to wash your hands, lie on your back and bend your knees. With one hand, push the labia to the sides, and with the other, insert the candle previously removed from the shell into the vagina.

The therapeutic course is 7-10 days. 1 suppository is administered 2 times a day.

If there is a risk of contracting a sexually transmitted disease, light a candle within 120 minutes of unprotected sex.

Why do candles leak

The liquid that flows out of the vagina after the injection of the medicine is a melted candle. The body temperature makes the suppository liquid. Due to the fact that the components of the drug are not absorbed, but have a local effect, the candle flows out under the force of gravity.

special instructions

Pregnancy and lactation

An antiseptic drug is approved for use during childbearing and during breastfeeding.

Childhood

In pediatric gynecology, for the treatment of infections of the genitourinary sphere, Geksikon D is recommended. It is allowed to be used from 6 months until the onset of the first menstrual bleeding.

Elderly age

There is no data on the dangers of using suppositories in old age.

Side effects of Geksikon candles

Allergic reactions and local itching were observed in some patients after using Geksikon.

Contraindications to the use of Geksikon suppositories

Individual intolerance to the Geksikon components.

Interaction with other drugs

It is not recommended to combine Geksikon with soap, detergents and disinfectants containing an anionic group, as well as iodine. The effectiveness of the antiseptic does not decrease if these detergents are not used intravaginally.

Alcohol compatibility

No alcohol compatibility information available. Due to the fact that alcohol-containing substances negatively affect the healing process, it is not recommended to consume such drinks during treatment.

Overdose

There is no information on overdose cases.

Terms of dispensing from pharmacies

Non-prescription drug.

Drug price

Depending on the pharmacy margins, the cost of suppositories varies from 300-650 rubles.

Storage conditions

Store out of the reach of children at a temperature that does not exceed + 25 ° C. The medication should not be exposed to ultraviolet rays. Monitor the integrity of the contour cell.

Shelf life

Subject to the storage rules, the shelf life is 24 months.

Manufacturer

JSC, Nizhpharm, Russia.

Analogs

1. Dermazole. Cream for external and local use. Can be used for fungal infections of the skin and mucous membranes (candidiasis). It is not prescribed in the presence of heart disease, etc. It has a large number of contraindications.
2. Nystatin. Available in the form of vaginal suppositories, tablets and solution. Contraindicated in patients with pancreatitis, renal failure, gastrointestinal ulcers, etc.
3. Chlorhexidine Bigluconate. Solution for local and external use.
4. Depantol candles. Allowed during gestation. Suitable for lactating women.

Geksikon ® 16 mg, 10 tablets

Identification and classification

International non-proprietary name

Chlorhexidine

Dosage form

vaginal pills

Composition

One tablet contains:

active substance - chlorhexidine bigluconate - 16.0 mg (in the form of chlorhexidine bigluconate solution 20% - 85.2 mg);

excipients: microcrystalline cellulose, pregelatinized corn starch, povidone K 17, stearic acid, lactose monohydrate.

Description

The tablets are white or white with a yellowish tinge, biconvex, oblong. Slight marbling of the surface is allowed.

Pharmacotherapeutic group

Antiseptic

Pharmacological properties. Pharmacodynamics

Local antiseptic agent with a predominantly bactericidal effect against gram-positive and gram-negative bacteria, has a fungicidal and virucidal effect (against lipophilic viruses). It is active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex type 2. Some strains of Pseudomonas spp., Proteus spp. Are weakly sensitive to the drug, as well as acid-resistant forms of bacteria, bacterial spores. Chlorhexidine does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood, pus.

Pharmacological properties. Pharmacokinetics

Systemic absorption with intravaginal use is negligible.

Indications for use

Treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, Trichomonas).

Prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after the installation of an intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine examinations).

Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes) - use no later than 2 hours after intercourse.

Contraindications

Hypersensitivity to chlorhexidine and other components of the drug, children under 18 years of age.

Application during pregnancy and during breastfeeding

The use of the drug during pregnancy and during breastfeeding is possible only after a careful assessment of the expected benefits to the mother and the risk to the fetus and child.

Method of administration and dosage

Intravaginally. It is recommended to moisten the tablet in water before use.

For treatment: 1 vaginal tablet 1-2 times a day for 7-10 days.

For the prevention of sexually transmitted infections: 1 vaginal tablet no later than 2 hours after unprotected intercourse.

If symptoms persist for more than 7 days, it is recommended to see a doctor.

Use the drug only according to the method of application and in those doses indicated in the instructions for use. If necessary, please consult your doctor before using the medicinal product.

Side effect

Allergic reactions, itching of the vagina, which pass after the drug is discontinued, are possible.

Severe allergic reactions, including anaphylaxis.

If any of the side effects indicated in the instructions are aggravated or you notice any other side effects that are not indicated in the instructions, inform your doctor.

Overdose

Overdose cases are unknown. When using the drug in accordance with the instructions for use, an overdose is unlikely.

Interaction with other medicinal products

Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose), and soaps if they are administered intravaginally.

Compatible with drugs containing a cationic group (benzalkonium chloride, cetrimonium bromide).

special instructions

The drug is intended for intravaginal use only in adult patients.

If allergic reactions or irritation appear at the injection site, treatment is stopped.

To prevent infection, simultaneous treatment of sexual partners is necessary.

During the period of treatment for bacterial vaginosis, it is recommended to refrain from sexual intercourse.

The toilet of the external genital organs does not affect the effectiveness and tolerability of vaginal tablets Geksikon ®, because the drug is used intravaginally.

It can be used during menstruation. the drug retains its activity, although somewhat reduced, in the presence of blood, pus and other biological fluids.

Influence on the ability to drive vehicles and work with mechanisms

The use of the drug does not affect the ability to drive vehicles, mechanisms.

Release form

Vaginal tablets 16 mg. On 5 or 10 tablets in a blister strip packaging from a film of polyvinyl chloride and printed aluminum foil varnished. 1, 2 blister packs of 5 tablets or 1 blister pack of 10 tablets, together with instructions for use of the medicinal product, are placed in a cardboard box.

Storage conditions

In a dry, dark place at a temperature not exceeding 25 ° C.