The structure of the bronchial wall. Human bronchi: what functions do they perform, where are they located? Anatomy, histology, embryology

Everyone needs to know where the bronchi are located. This will help in the event that therapy or diagnosis is needed. In addition, it is the bronchi that are a vital organ, without the normal work of which a person will not live long. Human anatomy is both an interesting and complex area of \u200b\u200bscience that you need to know everything about.

The bronchi are a paired organ that is a natural extension of the trachea. At the level of the fourth (in males) and fifth (in females) vertebra, the tracheal region divides, forming two tubes. Each of them is directed towards the lungs. After penetration into the pulmonary region, they are divided again: into three and two branches, respectively, the right and left parts.

The position shown corresponds to the parts of the lung, repeating its pattern. It should be noted that:

  • the location where the lungs are located in a person has a direct effect on their shape;
  • if a person's chest is narrow and long, then the epithelium and lungs will take the indicated shape;
  • the presented organs of the human type are characterized by a short and wide appearance with a conjugated form of the chest, which predetermines the functions of the bronchi.

The structure of the bronchial region

All bronchial lobes are subdivided into fragments of the bronchopulmonary type. They are sections of an organ that are isolated from similar adjacent areas. In each of the presented areas there is a segmental bronchus. There are 18 similar segments: 10 on the right and 8 on the left, which is confirmed by the figure.

The structure of each of the presented segments has several lobules, or sections, inside which the lobular bronchus is divided, which are located on top.

Pulmonologists assure that a person has at least 1600 lobules: 800 each on the right and left sides.

The similarity in the placement of the bronchial and pulmonary regions does not end there. The former, like the epithelium, branch out further, forming bronchioles of the secondary and tertiary order. They give rise to ducts of the alveolar type, which divide 1 to 4 times and end with alveolar sacs. Alveoli open into their lumen, which is why human anatomy is logical. It is she who predetermines the functional significance of the presented organ.

Functional features

The function of the bronchi is multifaceted - it is the conduction of air masses through the respiratory system during inhalation and exhalation, protective and drainage functions. Due to the latter two, foreign bodies that have got inside with air masses leave the respiratory system by themselves. Thus, human anatomy removes harmful microorganisms.

The epithelium of the bronchial region includes goblet-type cells that contain mucus. Foreign bodies and objects adhere to it, and the ciliary part of the epithelium sets the presented mucus in motion and contributes to the removal of the object outside. The presented process provokes a cough in a person, which does not always manifest itself with bronchitis. The functional significance of the bronchi may lie in other actions:

How to maintain bronchial health

The structure of the bronchi should remain complete, without flaws and foreign complications. This will keep the bronchi in perfect health. For this, drugs are used (bronchodilators, mucolytics and expectorants), they resort to a special diet and a healthy lifestyle. The latter excludes the use of alcoholic beverages, nicotine addiction.

Shown high physical activity, that is, daily walking, hardening, exercise.

All this will strengthen the body, which cannot be achieved without constant efforts.

Another condition for the health of the bronchi is the implementation of breathing exercises and visits to sanatoriums. They strengthen the immune system, optimize the functioning of the pulmonary system, which has a positive effect on the structure of the bronchi and, accordingly, the respiratory process. In this case, the epithelium and the respiratory pattern will not be subject to complications in terms of the general condition.

Additional Information

Failure to comply with medical recommendations and maintaining an unhealthy lifestyle provoke the formation of bronchial diseases. The most common are bronchitis, which is caused by inflammation of the bronchial walls. Pathology is formed under the influence of viruses and bacteria, some of which are needed by the body in minimal quantities.

Another complication is bronchial asthma, which is characterized by attacks of asphyxia, forming with a clear cycle. Allergic exposure, air pollution, all kinds of infections can become a catalyst for this. Other negative processes include:

  • bronchial tuberculosis, accompanied by a forced cough with the excretion of a significant ratio of sputum and aggravated breathing;
  • candidiasis, which forms with weakened protective functions of the body, when the epithelium is weakened, forming a fuzzy pattern;
  • cancer, in which the human anatomy changes, and the pathology is accompanied by a constant cough with the release of light pink sputum and swelling.

Thus, in order for the bronchi to remain absolutely healthy, it is necessary to know everything about their location, division into certain parts and the nuances of maintaining health. This will allow you to maintain maximum activity, heal the bronchi and lungs, making it possible to live a full life.

The mucous membrane of the large-caliber bronchi is lined with ciliated epithelium, the thickness of which gradually decreases and in the terminal bronchioles the epithelium is single-row ciliated, but cubic. Among the ciliated cells there are goblet, endocrine, basal, as well as secretory cells (Clara cells), edged, non-ciliated cells. Clara cells contain numerous secretory granules in the cytoplasm and are characterized by high metabolic activity. They produce enzymes that break down the surfactant that covers the respiratory tract. In addition, Clara cells secrete some surfactant components (phospholipids). The function of ciliate cells has not been established.

Rimmed cells have numerous microvilli on their surface. These cells are thought to function as chemoreceptors. An imbalance of hormone-like compounds of the local endocrine system significantly disrupts morphofunctional changes and can be the cause of immunogenic asthma.

As the caliber of the bronchi decreases, the number of goblet cells decreases. The epithelium covering the lymphoid tissue contains special M cells with a folded apical surface. Here they are assigned antigen-presenting function.

The proper lamina of the mucous membrane is characterized by a high content of longitudinally located elastic fibers, which provide stretching of the bronchi during inhalation and their return to their original position during exhalation. The muscle layer is represented by skew-circular bundles of smooth muscle cells. As the caliber of the bronchus decreases, the thickness of the muscle layer increases. The contraction of the muscle layer causes the formation of longitudinal folds. Prolonged contraction of muscle bundles in bronchial asthma leads to difficulty breathing.

The submucosa contains numerous glands located in groups. Their secret moisturizes the mucous membrane and promotes adhesion and enveloping of dust and other particles. In addition, mucus has bacteriostatic and bactericidal properties. As the caliber of the bronchus decreases, the number of glands decreases, and they are completely absent in the small-caliber bronchi. The fibrocartilaginous membrane is represented by large plates of hyaline cartilage. As the caliber of the bronchi decreases, the cartilage plates become thinner. In the bronchi of medium caliber, cartilaginous tissue in the form of small islets. In these bronchi, the replacement of hyaline cartilage with elastic is noted. In small bronchi, the cartilaginous membrane is absent. Because of this, the small bronchi have a stellate lumen.

Thus, as the caliber of the airways decreases, there is a thinning of the epithelium, a decrease in the number of goblet cells and an increase in the number of endocrine cells and cells in the epithelial layer; the number of elastic fibers in its own layer, a decrease and complete disappearance of the number of mucous glands in the submucosa, thinning and complete disappearance of the fibrocartilaginous membrane. The air in the airways is warmed up, cleaned, humidified.


Gas exchange between blood and air is carried out in respiratory department lungs, the structural unit of which is acinus... The acinus begins with the 1st order respiratory bronchiole, in the wall of which there are single alveoli.

Then, as a result of dichotomous branching, respiratory bronchioles of the 2nd and 3rd order are formed, which in turn are subdivided into alveolar passages containing numerous alveoli and ending in alveolar sacs. In each pulmonary lobule, which has a triangular shape, with a diameter of 10-15 mm. and a height of 20-25 mm., contains 12-18 acini. At the mouth of each alveoli there are small bundles of smooth muscle cells. Between the alveoli, there are messages in the form of holes-alveolar pores. Between the alveoli are thin layers of connective tissue containing a large number of elastic fibers and numerous blood vessels. Alveoli look like bubbles, the inner surface of which is covered with a single-layer alveolar epithelium, consisting of several types of cells.

Alveolocytes 1st order (small alveolar cells) (8.3%) have an irregular elongated shape and a non-nuclear part thinned in the form of a plate. Their free surface, facing the alveolar cavity, contains numerous microvilli, which significantly increases the area of \u200b\u200bcontact of air with the alveolar epithelium.

Their cytoplasm contains mitochondria and pinocytosis vesicles. These cells are located on the basement membrane, which fuses with the basement membrane of the capillary endodelium, due to which the barrier between blood and air is extremely small (0.5 microns). This is an aerogematic barrier. In some areas, thin layers of connective tissue appear between the basement membranes. Another numerous type (14.1%) are type 2 alveolocytes (large alveolar cells), located between type 1 alveolocytes and having a large rounded shape. There are also numerous microvilli on the surface. The cytoplasm of these cells contains numerous mitochondria, a lamellar complex, osmiophilic bodies (granules with a large amount of phospholipids) and a well-developed endoplasmic reticulum, as well as acid and alkaline phosphatase, nonspecific esterase, redox enzymes. It is assumed that these cells may be a source of formation type 1 alveolocytes. However, the main function of these cells is the secretion of lipoprotein substances of the merocrine type, collectively called a surfactant. In addition, the surfactant contains proteins, carbohydrates, water, electrolytes. However, its main components are phospholipids and lipoproteins. The surfactant coats the alveolar lining in the form of a surfactant film. The surfactant is very important. So it lowers the surface tension, which prevents the alveoli from sticking together during exhalation, and protects against overstretching during inhalation. In addition, surfactant prevents tissue fluid from sweating and thus prevents the development of pulmonary edema. The surfactant is involved in immune reactions: immunoglobilins are found in it. The surfactant performs a protective function by activating the bactericidal activity of pulmonary macrophages. The surfactant is involved in the absorption of oxygen and its transport across the air-blood barrier.

The synthesis and secretion of surfactant begins at the 24th week of intrauterine development of the human fetus, and by the time the baby is born, the alveoli are covered with a sufficient amount and full-fledged surfactant, which is very important. When a newborn baby takes its first deep breath, the alveoli expand, filling with air, and thanks to the surfactant, they no longer collapse. In premature babies, as a rule, there is still an insufficient amount of surfactant, and the alveoli can again collapse, which leads to a violation of the act of breathing. Shortness of breath, cyanosis appears, and the child dies in the first two days.

It is important to note that even in a healthy full-term baby, part of the alveoli remains in a collapsed state and straightens out a little later. This explains the predisposition of infants to pneumonia. The degree of maturity of the lungs of the fetus is characterized by the content of surfactant in the amniotic fluid, which gets there from the lungs of the fetus.

However, the bulk of the alveoli of newborn babies at birth is filled with air, straightens, and such a lung does not sink when it is lowered into water. This is used in judicial practice to decide whether a child was born alive or dead.

The surfactant is constantly renewed due to the presence of an anti-surfactant system: (Clara cells secrete phospholipids; basal and secretory cells of bronchioles, alveolar macrophages).

In addition to these cellular elements, the alveolar lining includes another type of cells - alveolar macrophages... These are large, rounded cells that expand both inside the wall of the alveoli and as part of the surfactant. Their thin processes spread on the surface of the alveolocytes. There are 48 macrophages per two adjacent alveoli. The source of macrophage development is monocytes. The cytoplasm contains many lysosomes and inclusions. Alveolar macrophages are characterized by 3 features: active movement, high phagocytic activity and a high level of metabolic processes. In general, alveolar macrophages represent the most important cellular defense mechanism of the lung. Lung macrophages are involved in phagocytosis and removal of organic and mineral dust. They perform a protective function, phagocytose various microorganisms. Macrophages have a bactericidal effect due to the secretion of lysozyme. They are involved in immune responses by primary processing of various antigens.

Chemotaxis stimulates the migration of alveolar macrophages to the area of \u200b\u200binflammation. Chemotactic factors include microorganisms that penetrate the alveoli and bronchi, the products of their metabolism, as well as the body's own cells that die.

Alveolar macrophages synthesize more than 50 components: hydrolytic and proteolytic enzymes, complement components and their inactivators, arachidonic acid oxidation products, reactive oxygen species, monokines, fibronectins. Alveolar macrophages express over 30 receptors. Functionally, the most important receptors are Fc receptors, which determine the selective recognition, binding and recognition antigens, microorganisms, receptors for the C3 component of the complement required for effective phagocytosis.

In the cytoplasm of pulmonary macrophages, contractile protein threads (active and myosin) are found. Alveolar macrophages are very sensitive to tobacco smoke. So, in smokers, they are characterized by an increase in oxygen uptake, a decrease in their ability to migrate, adhere, phagocytosis, as well as inhibition of bactericidal activity. In the cytoplasm of the alveolar macrophages of smokers, there are numerous electron-dense crystals of kaolinite formed from the condensation of tobacco smoke.

Viruses have a negative effect on pulmonary macrophages. So, toxic products of the influenza virus inhibit their activity and lead them (90%) to death. Hence the predisposition to bacterial infection when infected with a virus is understandable. The functional activity of macrophages is significantly reduced during hypoxia, cooling, under the influence of drugs and corticosteroids (even at a therapeutic dose), as well as with excessive air pollution. The total number of alveoli in an adult is 300 million with a total area of \u200b\u200b80 square meters.

Thus, alveolar macrophages perform 3 main functions: 1) clearance aimed at protecting the alveolar surface from contamination. 2) modulation of the immune system, i.e. participation in immune reactions due to phagocytosis of antigenic material and its presentation to lymphocytes, as well as due to enhancement (due to interleukins) or suppression (due to prostaglandins) proliferation, differentiation and functional activity of lymphocytes. 3) modulation of the surrounding tissue, i.e. effect on the surrounding tissue: cytotoxic damage to tumor cells, influence on the production of elastin and collagen by fibroblasts, and therefore on the elasticity of lung tissue; produces a growth factor that stimulates the proliferation of fibroblasts; stimulates the proliferation of type 2 alveocytes. Emphysema develops under the action of elastase produced by macrophages.

The alveoli are rather closely spaced relative to each other, due to which, the capillaries that entwine them, with one surface, border one alveolus, and the other with the neighboring one. This creates optimal conditions for gas exchange.

Thus, aerogematic barre includes the following components: surfactant, lamellar part of type 1 alveocytes, basement membrane, which can merge with the basement membrane of the endothelium, and the cytoplasm of endothelial cells.

Blood supply in the lung carried out through two vascular systems. On the one hand, the lungs receive blood from the systemic circulation through the bronchial arteries that extend directly from the aorta and form arterial plexuses in the wall of the bronchi, and feed them.

On the other hand, venous blood is supplied to the lungs for gas exchange from the pulmonary arteries, i.e. from the small circle of blood circulation. The branches of the pulmonary artery entwine the alveoli, forming a narrow capillary network through which red blood cells pass in one row, which creates optimal conditions for gas exchange.

The human respiratory system consists of several sections, including the upper (nasal and oral cavity, nasopharynx, larynx), lower respiratory tract and lungs, where gas exchange directly takes place with the blood vessels of the pulmonary circulation. The bronchi are categorized as the lower respiratory tract. In essence, these are branched air supply channels that connect the upper part of the respiratory system with the lungs and evenly distribute the air flow throughout their volume.

The structure of the bronchi

If you look at the anatomical structure of the bronchi, you can notice a visual similarity with a tree, the trunk of which is the trachea.

Inhaled air enters through the nasopharynx into the windpipe or trachea, which is about ten to eleven centimeters long. At the level of the fourth-fifth vertebra of the thoracic spine, it divides into two tubes, which are the first-order bronchi. The right bronchus is thicker, shorter and more vertical than the left.

Zonal extrapulmonary bronchi branch off from the first-order bronchi.

Second-order bronchi or segmental extrapulmonary bronchi are branches from the zonal ones. There are eleven on the right side and ten on the left.

The bronchi of the third, fourth and fifth order are intrapulmonary subsegmental (i.e., branches from segmental sections), gradually narrowing, reaching a diameter of five to two millimeters.

Further, there is even greater branching into lobar bronchi, with a diameter of about a millimeter, which, in turn, pass into the bronchioles - the final branches of the "bronchial tree", ending with alveoli.
The alveoli are cell-shaped vesicles that are the final part of the respiratory system in the lung. It is in them that gas exchange with blood capillaries is carried out.

The walls of the bronchi have a cartilaginous annular structure, which prevents their spontaneous narrowing, connected by smooth muscle tissue. The inner surface of the canals is lined with a mucous membrane with ciliated epithelium. Bronchial blood supply goes through bronchial arteries branching from the thoracic aorta. In addition, the "bronchial tree" is riddled with lymph nodes and nerve branches.

The main functions of the bronchi

The task of these organs is by no means limited to conducting air masses into the lungs, the functions of the bronchi are much more versatile:

  • They are a protective barrier against harmful dust particles and microorganisms entering the lungs, thanks to the mucus and cilia of the epithelium on their inner surface. The oscillation of these cilia promotes the elimination of foreign particles along with the mucus - this happens with the help of the cough reflex.
  • The bronchi are capable of detoxifying a number of toxic substances harmful to the body.
  • The lymph nodes of the bronchi perform a number of important functions in the body's immune processes.
  • The air, passing through the bronchi, is warmed to the desired temperature, acquires the necessary humidity.

Major diseases

Basically, all diseases of the bronchi are based on a violation of their patency, and therefore, difficulty in normal breathing. The most common pathologies include bronchial asthma, bronchitis - acute and chronic, bronchoconstriction.

This disease is chronic, recurrent, characterized by a change in the reactivity (free passage) of the bronchi when external irritating factors appear. The main manifestation of the disease is asthma attacks.

In the absence of timely started treatment, the disease can give complications in the form of pulmonary eczema, infectious bronchitis and other serious diseases.


The main causes of bronchial asthma are:

  • the use of agricultural products grown with the use of chemical fertilizers;
  • environmental pollution;
  • individual characteristics of the organism - predisposition to allergic reactions, heredity, unfavorable climate for living;
  • household and industrial dust;
  • a large number of medications taken;
  • viral infections;
  • disruption of the endocrine system.

Signs of bronchial asthma are manifested in the following pathological conditions:

  • rare periodic or frequent persistent attacks of suffocation, which are accompanied by wheezing, short breaths and long breaths;
  • paroxysmal cough with clear mucus, resulting in pain;
  • as a harbinger of an asthma attack, prolonged sneezing can act.

The first thing to do is to relieve an attack of suffocation, for this you need to have an inhaler with a medicine prescribed by your doctor. If bronchospasm persists, you should urgently call emergency help.

Bronchitis is an inflammation of the walls of the bronchi. The reasons under the influence of which the disease occurs may be different, but mainly the penetration of damaging factors occurs through the upper respiratory tract:

  • viruses or bacteria;
  • chemical or toxic substances;
  • exposure to allergens (with a predisposition);
  • long-term smoking.

Depending on the cause of the onset, bronchitis is divided into bacterial and viral, chemical, fungal and allergic. Therefore, before prescribing treatment, a specialist must, based on the test results, determine the type of disease.

Like many other diseases, bronchitis can be acute or chronic.

  • The acute course of bronchitis can disappear within a few days, sometimes weeks, and is accompanied by fever, dry or wet cough. Bronchitis can be cold or infectious. The acute form usually goes away without consequences for the body.
  • A chronic form of bronchitis is a long-term illness that lasts for several years. It is accompanied by a persistent chronic cough, exacerbations occur annually and can last up to two to three months.

The acute form of bronchitis is given special attention in treatment in order to prevent it from developing into a chronic one, since the constant effect of the disease on the body leads to irreversible consequences for the entire respiratory system.

Some symptoms are typical for both acute and chronic forms of bronchitis.

  • The initial cough can be dry and severe, causing chest pain. When treated with phlegm-thinning agents, the cough becomes moist and the bronchi are released for normal breathing.
  • The increased temperature is typical for the acute form of the disease and can rise up to 40 degrees.

After determining the causes of the disease, a specialist doctor will prescribe the necessary treatment. It can consist of the following groups of medications:

  • antiviral;
  • antibacterial;
  • immune-strengthening;
  • pain relievers;
  • mucolytics;
  • antihistamines and others.

Physiotherapeutic treatment is also prescribed - heating, inhalation, therapeutic massage and physical education.

These are the most common diseases of the bronchi, with a number of varieties and complications. Given the seriousness of any inflammatory processes in the airways, it is necessary to make every effort not to trigger the development of the disease. The sooner treatment is started, the less damage it will bring not only to the respiratory system, but also to the body as a whole.

The bronchial tree is the main system on which the breathing of a healthy person is built. It is known that there are airways that supply oxygen to humans. It is they who are naturally structured in such a way that some semblance of a tree is formed. Speaking about the anatomy of the bronchial tree, it is imperative to analyze all the functions assigned to it: air purification, humidification. The correct functioning of the bronchial tree provides the alveoli with an inflow of easily assimilated air masses. The structure of the bronchial tree is an example of minimalism inherent in nature with maximum efficiency: optimal structure, ergonomic, but coping with all its tasks.

Features of the structure

Different parts of the bronchial tree are known. In particular, there are cilia here. Their task is to protect the alveoli of the lungs from small particles, dust polluting the air masses. With the effective and well-coordinated work of all departments, the bronchial tree becomes the protector of the human body from a wide range of infections.

The functions of the bronchi include the deposition of microscopic life forms leaked through the tonsils and mucous membranes. At the same time, the structure of the bronchi in children and the older generation is somewhat different. In particular, the length is noticeably longer in adults. The younger the child, the shorter the bronchial tree, which provokes a variety of diseases: asthma, bronchitis.

Protecting ourselves from trouble

Doctors have developed methods to prevent inflammation in the respiratory system. The classic option is sanitation. It is produced conservatively or radically. The first option involves therapy with antibacterial drugs. To increase the effectiveness, drugs are prescribed that can make the sputum more liquid.

But radical therapy is an intervention using a bronchoscope. The device is inserted through the nose into the bronchi. Through special channels, drugs are released directly onto the mucous membranes inside. To protect the respiratory system from diseases, use mucolytics, antibiotics.

Bronchi: term and features

The bronchi are branches of the windpipe. An alternative name for the organ is the bronchial tree. The system has a trachea, which is divided into two elements. The division in females is at the level of the 5th vertebra of the chest, and in the stronger sex it is one level higher - at the 4th vertebra.

After separation, the main bronchi are formed, which are also known as left, right. The structure of the bronchi is such that at the point of separation they leave at an angle close to 90 degrees. The next part of the system is the lungs, into the gates of which the bronchi enter.

Right and left: two brothers

The bronchi on the right are slightly wider than on the left, although the structure and structure of the bronchi are generally similar. The difference in size is due to the fact that the lung on the right is also larger than on the left. However, this does not exhaust the differences between "almost twins": the bronchus on the left relative to the right is almost 2 times longer. The features of the bronchial tree are as follows: on the right, the bronchus consists of 6 rings of cartilage, sometimes eight, but on the left there are usually at least 9 of them, but sometimes the number reaches 12.

The bronchi on the right, in comparison with the left, are more vertical, that is, in fact, they simply continue the trachea. On the left, under the bronchi, there is an arcuate aorta. To ensure the normal performance of the functions of the bronchi, nature provides for the presence of a mucous membrane. It is identical to the one that covers the trachea, in fact, continues it.

The structure of the respiratory system

Where are the bronchi located? The system is located in the human sternum. The beginning is at the level of 4-9 vertebrae. Much depends on gender and individual characteristics of the organism. In addition to the main bronchi, the lobar bronchi also depart from the tree, these are organs of the first order. The second order is made up of zonal bronchi, and from the third to the fifth - subsegmental, segmental. The next step is small bronchi, which occupy levels up to the 15th. The smallest and farthest from the main bronchi are the terminal bronchioles. After them, the following organs of the respiratory system are already starting - the respiratory, which are responsible for the exchange of gases.

The structure of the bronchi is not uniform throughout the duration of the tree, but some general properties are observed over the entire surface of the system. Thanks to the bronchi, air flows from the trachea to the lungs, where it fills the alveoli. The treated air masses are sent back the same way. The bronchopulmonary segments are also irreplaceable in the process of cleaning the inhaled volumes. All impurities deposited in the bronchial tree are excreted through it. To get rid of foreign elements, microbes trapped in the respiratory tract, cilia are used. They can make oscillatory movements, due to which the secretion of the bronchi moves into the trachea.

Examining: is everything normal?

When studying the walls of the bronchi and other elements of the system, conducting bronchoscopy, be sure to pay attention to the coloring. Normally, the mucous membrane is gray. The cartilage rings are clearly visible. When examining, the angle of divergence of the trachea, that is, the place where the bronchi originate, must be checked. Normally, the angle is similar to the ridge protruding above the bronchi. It runs along the midline. In the process of breathing, the system fluctuates somewhat. It happens freely, without tension, pain and heaviness.

Medicine: where and why

Doctors responsible for the respiratory system know exactly where the bronchi are located. If the layman feels that he may have problems with the bronchi, he needs to visit one of the following specialists:

  • therapist (he will tell you which doctor will help better than others);
  • pulmonologist (treats most of the respiratory diseases);
  • oncologist (relevant only in the most severe case - the diagnosis of malignant neoplasms).

Diseases affecting the bronchial tree:

  • asthma;
  • bronchitis;
  • dysplasia.

Bronchi: how does it work?

It's no secret that a person needs lungs to breathe. Their constituent parts are called shares. Air enters here through the bronchi, bronchioles. At the end of the bronchiole there is an acinus, in fact - an accumulation of bundles of alveoli. That is, the bronchi are a direct participant in the breathing process. It is here that the air heats up or cools down to the temperature that is comfortable for the human body.

Human anatomy was not formed by accident. For example, the division of the bronchi provides an efficient supply of air to all parts of the lungs, even the most distant ones.

Under protection

The human chest is the place where the most important organs are concentrated. Since their damage can provoke death, nature has provided an additional protective barrier - ribs and muscle corset. Inside it are numerous organs, including the lungs, bronchi, connected to each other. At the same time, the lungs are large, and almost the entire surface area of \u200b\u200bthe sternum is allocated under them.

Bronchi, trachea are located almost in the center. They are parallel to the front of the spine. The trachea is located just below the front of the spine. The location of the bronchi is under the ribs.

Bronchial walls

The bronchi are composed of cartilage rings. From the point of view of science, this is called the term "fibro-musculo-cartilage tissue". Each subsequent branch is smaller. At first, these are regular rings, but gradually they disappear into half rings, and the bronchioles do without them. Thanks to the cartilaginous support in the form of rings, the bronchi are held in a rigid structure, and the tree protects its shape, and with it - functionality.

Another important component of the respiratory system is a corset made of muscles. When muscles contract, the size of the organs changes. This is usually triggered by cold air. Compression of organs provokes a decrease in the rate of passage of air through the respiratory system. Over a longer period of time, the air masses have more opportunities to warm up. With active movements, the lumen becomes larger, which prevents shortness of breath.

Respiratory tissues

The bronchial wall consists of a large number of layers. The two described are followed by the level of the epithelium. Its anatomical structure is rather complex. Different cells are observed here:

  • Cilia, capable of clearing air masses of unnecessary elements, pushing dust out of the respiratory system and moving mucus into the trachea.
  • Goblet, producing mucus, designed to protect the mucous membrane from negative external influences. When the dust is on the tissues, secretion is activated, a cough reflex is formed, and the cilia begin to move, pushing out the dirt. The mucus produced by the tissues of the organ makes the air more humid.
  • Basal, capable of repairing the inner layers in case of damage.
  • Serous, forming a secret that allows you to clean the lungs.
  • Clara, producing phospholipids.
  • Kulchitsky, carrying hormonal function (included in the neuroendocrine system).
  • The outer ones, in fact, are connective tissue. It has the function of contacting the environment around the respiratory system.

Throughout the volume of the bronchi, there is a huge number of arteries that supply blood to the organs. In addition, there are lymph nodes that receive lymph through the lung tissue. This determines the spectrum of functions of the bronchi: not only transporting air masses, but also cleaning.

Bronchi: in the focus of attention of doctors

If a person is admitted to the hospital with suspected bronchial disease, diagnosis always begins with an interview. During the interview, the doctor identifies complaints, determines the factors that affected the patient's respiratory system. So, it is immediately obvious where the problems with the respiratory system come from, if someone who smokes a lot, is often in dusty rooms or works in a chemical industry, comes to the hospital.

The next step is to examine the patient. The color of the skin of the person seeking help can tell a lot. Check if there is shortness of breath, cough, examine the chest - if it is deformed. One of the signs of a disease of the respiratory system is a pathological form.

Chest: signs of illness

The following types of pathological chest deformities are distinguished:

  • Paralytic, observed in those who often suffer from pulmonary diseases, pleura. In this case, the cell loses its symmetry, and the gaps between the edges become larger.
  • Emphysematous, appearing, as the name suggests, with emphysema. The shape of the patient's chest resembles a barrel; due to coughing, the upper zone is greatly enlarged.
  • Rachitic, characteristic of rickets who had had a history of childhood. It resembles a bird's keel, protrudes forward as the sternum protrudes.
  • "Shoemaker", when the xiphoid process, the sternum as if in the depths of the cage. Usually pathology from birth.
  • Scaphoid, when the sternum seems to be deep. Usually triggered by syringomyelia.
  • "Round back", characteristic of those suffering from inflammatory processes in the bone tissue. Often affects the performance of the lungs and heart.

Exploring the lung system

To check how severe the disturbances in the lungs are, the doctor feels the patient's chest, checking whether there are any neoplasms uncharacteristic for this zone under the skin. They also study voice tremor - whether it weakens, whether it becomes stronger.

Another method of assessing the condition is listening. For this, an endoscope is used when the doctor listens to how air masses move in the respiratory system. Evaluate the presence of non-standard noises, wheezing. Some of them, not characteristic of a healthy body, immediately allow you to diagnose the disease, others simply indicate that something is wrong.

The most effective is X-ray. Such a study allows you to get a maximum of useful information about the state of the bronchial tree as a whole. If there are pathologies in the cells of organs, the easiest way is to determine them precisely on an X-ray. It reflects the abnormal narrowing, expansion, thickening inherent in one or another section of the tree. If there is a neoplasm or fluid in the lungs, it is the X-ray that shows the problem most obviously.

Features and research

Perhaps the most modern way to study the respiratory system is computed tomography. Of course, such a procedure is usually not cheap, so it is not available to everyone - in comparison, for example, with a conventional X-ray. But the information obtained in the course of such diagnostics is the most complete and accurate.

Computed tomography has a number of features, due to which other systems for dividing the bronchi into parts were specially introduced for it. So, the bronchial tree is divided into two parts: small, large bronchi. The technique is based on the following idea: small, large bronchi are distinguished by their functionality and structural features.

It is rather difficult to determine the border: where small bronchi end and large ones begin. Pulmonology, surgery, physiology, morphology, as well as specialists dealing with sighting bronchi have their own theories. Consequently, doctors in different fields interpret and use the terms "large" and "small" in different ways in relation to the bronchi.

What to look at?

The division of the bronchi into two categories is based on the difference in size. So, there is the following position: large - those that are at least 2 mm in diameter, that is, it is allowed to study using a bronchoscope. There are cartilage in the walls of this type of bronchi, and the main wall is equipped with hyaline cartilage. Usually the rings are not closed.

The smaller the diameter, the more the cartilage changes. At first these are just plates, then the nature of the cartilage changes, and then this "skeleton" disappears altogether. However, it is known that elastic cartilage is found in the bronchi, the diameter of which is less than a millimeter. This leads to the problem of classifying the bronchi into small, large.

With tomography, the image of large bronchi is determined by the plane in which the picture was taken. For example, in diameter it is only a ring filled with air and bounded by a thin wall. But if you study the respiratory system longitudinally, then you can see a pair of parallel straight lines, between which the air layer is enclosed. Usually, longitudinal images are taken of the middle, upper lobe, 2-6 segments, and transverse images are needed for the lower lobe, the basal pyramid.

Bronchi(bronchus, singular; Greek bronchos windpipe) is part of the airways: the tubular branches of the trachea connecting it to the respiratory parenchyma of the lung.

Anatomy, histology:

The trachea at the level of the V-VI thoracic vertebra is divided into the right and left main bronchi. They enter the corresponding lung, where they branch out 16-18 times and form a bronchial tree, the cross-sectional area of \u200b\u200bwhich at the level of the terminal ramifications is 4720 times larger than at the level of the trachea, and is 11800 cm2. The right main B. occupies a more vertical position, shorter and wider than the left. The length of the right main B. is 2-3 cm, the diameter is 1.5-2.5 cm, it contains, as a rule, 6-8 unclosed cartilaginous rings. The length of the main left B. is 4–6 cm, diameter is 1–2 cm, it contains 9–12 open cartilaginous rings. In women, the bronchi are narrower and shorter than in men.

The upper surface of the right main bronchus is adjacent to the azygos vein and tracheobronchial lymph nodes; back - to the right vagus nerve, its branches and the posterior right bronchial artery, esophagus and thoracic duct; lower - to the bifurcational lymph nodes; anterior - to the pulmonary artery and pericardium.
The left main bronchus from above is adjacent to the aortic arch and tracheobronchial lymph nodes; behind - to the descending aorta, the left vagus nerve and its branches; in front - to the left anterior bronchial artery, pulmonary veins, pericardium; from below - to the bifurcation lymph nodes. The main bronchi, entering the lungs, are sequentially divided first into lobar, and then into segmental bronchi.

The right main bronchus forms the upper, middle and lower lobar bronchi. The upper lobar bronchus is divided into apical, posterior and anterior segmental bronchi (BI, BII, BIII), the middle lobar is divided into lateral and medial segmental bronchi (BIV, BV), the lower lobar is divided into apical (upper), medial (cardiac), basal, anterior basal, lateral basal, posterior basal (BVI, BVII, BVIII, BIX, BX). The left main B. branches into the upper and lower lobar bronchus. The upper lobar bronchus forms the apical-posterior, anterior, upper reed, and lower reed segmental bronchi. (BI-II, BIII, BIV, BV), lower lobar - apical (perchian), medial (cardiac) basal, which is usually absent, anterior basal, lateral and posterior basal (BVI, BVII, BVIII, BIX, BX).

Image of the trachea, main, lobar and segmental bronchi. shown in the figure. Segmental bronchi are divided into subsegmental, then into bronchi of the 4th-8th order of division. The smallest bronchi are lobular (about 1 mm in diameter) and branch out within the lung lobule. Lobular bronchi are divided into a series of terminal (terminal) bronchioles, which, in turn, end in respiratory (respiratory) bronchioles, passing into the alveolar passages and alveoli. Respiratory bronchioles, alveolar passages and alveoli form the respiratory parenchyma of the lung.

The bronchial wall consists of 3 membranes: mucous, fibromuscular-cartilaginous and adventitious. The mucous membrane is lined with multi-row prismatic ciliated epithelium. Each ciliated cell has on its surface about 200 cilia 0.3 µm in diameter and about 6 µm in length. In addition to ciliated cells, the bronchial mucosa contains goblet cells that form mucous secretions, neuroendocrine cells secreting biogenic amines (primarily serotonin), basal and intermediate cells involved in the regeneration of the mucous membrane.

Under the basement membrane of the mucous membrane is the submucosa, in which the mucous-protein glands, vessels, nerves and multiple lymph nodules (lymphoid follicles) are located - the so-called broncho-associated lymphoid tissue. The mucous membrane is tightly connected to the underlying membrane and does not form folds. The fibromuscular-cartilaginous sheath is formed by open hyaline cartilaginous rings, the free ends of which are connected by smooth muscles.

The cartilaginous rings are fastened together with dense fibrous tissue. With a decrease in the caliber of the bronchi, the number of cartilaginous rings and their sizes decrease, the cartilage becomes elastic, the number of muscle elements increases. Their epithelium from multi-row ciliate prismatic gradually becomes two-row and then is replaced by a single-layer ciliate cubic. The adventitia is formed by loose loose connective tissue.

Bronchial blood supply is carried out by arterial bronchial branches from the thoracic aorta, as well as from the esophageal arteries. Outflow of venous blood occurs in the unpaired and semi-unpaired veins. Lymphatic vessels from the bronchus flow into the pulmonary, tracheobronchial and bifukartial lymph nodes. The bronchi are innervated by branches from the anterior and posterior pulmonary nerve plexuses. The branches of efferent autonomic fibers end with synapses on the surface of smooth muscle cells of the bronchi.

The mediator of parasympathetic nerve endings is acetylcholine, the effect of which on the cholinergic receptors of smooth muscle cells leads to bronchial spasm. A similar effect is caused by the activation of a-adrenergic receptors of the bronchi. The effect of the sympathetic part of the nervous system is mediated by catecholamines (mainly adrenaline) and is realized through the a and b-adrenergic receptors of the smooth muscles of the bronchi. Excitation of b2-adrenergic receptors causes bronchial expansion.

Age features:

After birth, the differentiation of bronchial tissues continues (up to about 7 years) and the growth of the bronchial tree. The bronchi grow especially intensively in the first year of life and during puberty; by the age of 20, the size of all bronchi increases by 31 / 2-4 times. After 40 years, involutive processes are observed in the bronchi: atrophy of the mucous membrane and submucosal tissue, calcification of cartilage, etc.

Physiology:

The most important functions of the bronchi are to conduct air to the respiratory parenchyma of the lung and back, as well as to protect the peripheral parts of the respiratory system from dust particles, microorganisms, and irritating gases entering them. Regulation of the air flow passing through the bronchi is carried out by changing the difference between the air pressure in the alveoli and in the external environment, which is achieved by the work of the respiratory muscles.

Another mechanism is a change in B.'s lumen by nervous regulation of the tone of their smooth muscles. Normally, when inhaling, the lumen and B.'s length increase, and when exhaling, they decrease. Impaired regulation of the tone of B.'s smooth muscles underlies many diseases of the respiratory system (bronchial asthma, chronic obstructive bronchitis, and others).

Removal of small dust particles and some microorganisms (drainage function of B.) is carried out by mucociliary transport: the mucous secretion of goblet cells and mucous glands of the bronchus covers the surface of the epithelial cilia with a thin (5-7 μm) layer, which synchronously oscillate at a frequency of 160-250 times per minute , ensuring the constant movement of mucus with foreign particles deposited on it towards the trachea and larynx. The mucous secretion entering the oropharynx is usually swallowed.

Normally, particles (for example, dust, bacteria) deposited in B. are excreted with the mucous secretion of the bronchi and trachea within 1 hour. Removal of solid particles and irritating gases from the respiratory tract also occurs when coughing. In the bronchi, a number of harmful substances can be detoxified; some compounds of endogenous origin can be excreted through their mucous membrane. Broncho-associated lymphoid tissue plays an important role in the formation of immune defense mechanisms of the respiratory system.

Research methods:

To recognize the pathology of the bronchus, they use general clinical methods of examining the patient and a number of special methods. During the survey, characteristic complaints of cough (dry or with phlegm), shortness of breath, attacks of suffocation, hemoptysis are noted. It is important to establish the presence of factors that negatively affect the condition of the bronchi (for example, smoking tobacco, working in conditions of increased dusty air).

During the examination of the patient, attention is paid to the color of the skin (pallor, cyanosis), the shape of the chest (barrel-shaped - in chronic obstructive bronchitis accompanied by emphysema, bronchial asthma), the peculiarities of respiratory excursions of the lungs (for example, during an attack of bronchial asthma, respiratory excursions are limited).

In patients with a chronic suppurative process in the bronchi (for example, with bronchiectasis), signs of hypertrophic osteoarthropathy are often noted: fingers in the form of drumsticks (with thickened terminal phalanges) and nails resembling watch glasses. On palpation of the chest, its shape, volume and synchronization of respiratory movements are specified, crepitus is detected in subcutaneous emphysema (caused, for example, by bronchial fistula), and the nature of voice tremor is determined (its weakening is possible with bronchoconstriction).

Dullness of percussion sound can occur due to atelectasis of the lung caused by bronchoconstriction, with the accumulation of pus in the sharply dilated bronchi. The boxed shade of percussion sound is noted in pulmonary emphysema, which often complicates the course of chronic obstructive bronchitis and bronchial asthma. Limited tympanitis can be defined over the area of \u200b\u200bair accumulation in the dilated bronchi, partially filled with pus.

Auscultation of the lungs reveals changes in respiratory sounds, incl. wheezing, characteristic of pathological processes in the bronchi. for example, hard breathing may be due to narrowing of the bronchial lumen. Dry wheezing (buzzing, buzzing, whistling) can occur due to uneven narrowing of the lumen of the bronchi with swelling of their mucous membrane and the presence of a viscous secretion that forms a variety of cords, threads in the lumen of the bronchi. These rales are characteristic of acute bronchitis, exacerbation of chronic bronchitis, bronchiectasis, bronchial asthma. Wet, finely bubbling, dissonant scattered rales can be heard in bronchiolitis, often they are combined with dry rales. Medium bubbling rales are determined with small bronchiectasis, large bubbling - with the accumulation of liquid sputum in the lumen of large bronchi.

X-ray examination plays an important role in the diagnosis of bronchial diseases. The X-ray picture (on the plain chest X-ray) depends on the nature of the pathological process. For example, in chronic obstructive bronchitis, a widespread reticular deformation of the pulmonary pattern, expansion of the roots of the lungs, thickening of the walls of the bronchi and an increase in the transparency of the lungs are determined; with bronchiectasis - a cellular structure of the pulmonary pattern, expansion of the lumen of the bronchi, thickening of their walls; with tumors of the bronchi - long-term local shadowing of the lung. Bronchography and bronchoscopy provide significant assistance in diagnosing the pathological process in the bronchial tree. Tomography of the chest organs in the anteroposterior projection with both longitudinal and transverse "smearing" makes it possible to judge the state of the trachea and main bronchi and an increase in the intrathoracic lymph nodes.

Functional studies of respiration, revealing a violation of bronchial patency, make it possible to diagnose the early stages of bronchopulmonary diseases, assess their severity and determine the level of damage to the bronchial tree. The functional methods available for outpatient treatment and used for dynamic monitoring of the patient include spirography. The obstructive type of ventilation disorders, which is based on violations of bronchial patency, is observed, for example, in patients with chronic obstructive bronchitis, bronchial asthma.

At the same time, compared with the vital capacity of the lungs (VC), the forced expiratory volume in 1 s (FEV1) and maximum ventilation of the lungs (MVL) - absolute speed indicators - decrease to a greater extent, therefore the ratio of FEV1 / VC and MVL / VC (relative speed indicators ) are reduced, and the degree of reduction characterizes the severity of bronchial obstruction. Restrictive (restrictive) type of ventilation disorders occurs when it is difficult to stretch the lungs and chest and is characterized by a predominant decrease in VC, to a lesser extent - absolute speed indicators, as a result of which the relative speed indicators remain normal or exceed the norm.

In diseases of the bronchus, this type of ventilation disorders is rare, it can be observed in tumors of large bronchi with atelectasis of part or the entire lung. The mixed type of ventilation disorders is characterized by a decrease in VC and absolute speed indicators approximately in equal measure, as a result of which the relative speed indicators are changed less than the absolute ones, can occur with pulmonary emphysema, acute pneumonia. Pneumotachography, general plethysmography, pharmacological tests can reveal changes in bronchial patency at various levels that are not detected by spirometry.

To clarify the nature and degree of violations of bronchial patency, a study of the sensitivity and reactivity of the bronchi is carried out. Sensitivity is determined by the minimum dose of a pharmacological drug (acetylcholine, carbacholine) that causes the development of bronchospasm. Reactivity is characterized by the severity of bronchospasm in response to a gradual increase in the dose of the drug, starting from the threshold. High sensitivity is often found in healthy people, high reactivity - only in patients with bronchial asthma and pre-asthma.

In order to differentiate reversible and irreversible violations of bronchial patency, a tomorespiratory test can be used, which consists in comparing two lateral homograms of the same section in the plane of the bronchovascular bundle, produced with the same exposure: one - in the phase of deep inspiration, the other - in the phase of complete exhalation ... In case of irreversible violation of bronchial patency, which is observed in obstructive bronchitis, complicated by the development of pulmonary emphysema, the mobility of the diaphragm is persistently limited. With a reversible violation of bronchial patency, characteristic of uncomplicated obstructive bronchitis, bronchial asthma, the mobility of the diaphragm is preserved.

Bacteriological examination of sputum makes it possible to clarify the etiology of the inflammatory process in the bronchopulmonary system; cytological examination helps to establish the nature and severity of the inflammatory process, as well as the detection of tumor cells.

Pathology:

Dysfunctions of the bronchi are manifested by obstructive ventilation disorders, which can be caused by a number of reasons: bronchial spasm, edematous-inflammatory changes in the bronchial tree, hypersecretion of bronchial glands with accumulation of pathological contents in the bronchial lumen, collapse of small bronchi with the loss of elastic properties of the lungs, emphysema, etc.

Disturbances of mucociliary transport, one of the main mechanisms of protection of the respiratory tract, are of great importance in the pathogenesis of bronchopulmonary diseases. Drying of the mucous membrane of B., inhalation of oxygen, ammonia, formaldehyde, smoking, sensitization of the body, and others have a negative effect on mucociliary transport. It is disturbed in chronic bronchitis, bronchiectasis, bronchial asthma, cystic fibrosis, and some other diseases. An increase in the amount and an increase in the viscosity of the secretion of the bronchial glands, a violation of its excretion can lead to obturation of B. and the development of a "silent lung" (with status asthmaticus) or even atelectasis of a segment or lobe of the lung with obstruction of a large bronchus.

Increased sensitivity and reactivity of the bronchus underlies bronchospasm - narrowing of the lumen of the bronchus and bronchioles due to spastic contraction of the muscles of the bronchial wall. Nonspecific hyperreactivity of the bronchus is associated with the enhanced influence of the regulator of the parasympathetic nervous system - acetylcholine and with dysfunction of the adrenergic link of regulation: increased sensitivity of a-adrenergic receptors and decreased sensitivity of b-adrenergic receptors.

The most important factor in the formation of bronchial hyperreactivity is considered to be inflammation that develops as a result of the action of both infectious and physicochemical agents, incl. pollen of plants and components of tobacco smoke. The central place in the implementation of the mechanisms of bronchial hyperreactivity is given to the function of mast cells, which produce and release the most important mediators of inflammation and bronchoconstriction: histamine, neutral proteases, factors of chemotaxis of eosinophils and neutrophils, metabolic products of arachidonic acid (prostaglandins, leukotrienes) and other thrombocyte activation factor.

The cellular and subcellular mechanisms of bronchospasm consist mainly in a change in the ratio of intracellular nucleotides: cyclic 3 ", 5" -AMP and cyclic 3 ", 5" -guanosine monophosphate by increasing the latter. An important pathogenetic mechanism of bronchospasm may be an increase in the content of calcium ions inside the cell.

Bronchospasm is one of the variants of bronchial obstruction and is clinically manifested by difficulty in the act of exhalation (expiratory dyspnea or suffocation). At the same time, hard breathing with prolonged exhalation, a large number of dry wheezing rales are heard. A functional study of the lungs reveals a decrease in speed indicators (FEV1, MVL, Tiffno test). Bronchospasm can be local, diffuse and total. Local bronchospasm (spastic contraction of the muscles of individual bronchi) is more often caused by local irritation of V., for example, by a foreign body.

With persistent diffuse bronchospasm (widespread spastic narrowing of the bronchus, often of a small caliber), observed in bronchial asthma and chronic obstructive bronchitis, respiratory failure, hypoxia, hypercapnia develop, which, in turn, increase bronchospasm. With total bronchospasm (a sharp one-stage B.'s spasm of all generations), which often happens with status asthmaticus, spontaneous breathing is practically impossible due to the ineffectiveness of the efforts of the respiratory muscles. In these cases, artificial ventilation is indicated. To relieve bronchospasm, b2-adrenostimulants (salbutamol, berotek), purinergic receptor stimulants (euphyllin), anticholinergics (platifillin, atropine, atrovent) are used. The prognosis depends on the cause of bronchospasm and the severity of the underlying disease (bronchial asthma, obstructive bronchitis, etc.).

Bronchial malformations are rare, usually combined with tracheal malformations and are caused by a violation of the formation of the tracheobronchial tree at 5-8 weeks of intrauterine development. The most common malformations of the trachea and bronchus are tracheobronchomegaly, tracheal and bronchial stenosis, tracheal bronchus. Congenital bronchiectasis and bronchial fistula are very rarely observed.

Tracheobronchomegaly (Mounier-Kuhn syndrome, tracheobronchomalacia) is characterized by loss of elasticity of trachobronchial cartilage rings, impaired breathing mechanics due to collapse of the trachea and bronchi, significant expansion of the trachea and bronchi. Clinical manifestations largely depend on the severity of morphological changes, the prevalence of the pathological process and secondary changes in the bronchopulmonary system. A pathognomonic sign of tracheobronchomegaly is a rattle-like cough with pronounced resonance. Often there is a constant barking cough, accompanied by attacks of hypoxia, noisy breathing. Recurrent pneumonia is frequent.

The expansion of the lumen of the trachea and bronchus can be established by radiography and tomography of the lungs. Bronchoscopy and bronchography are of the greatest diagnostic value. Bronchoscopic signs of tracheobronchomegaly are significant expansion of the lumen of the trachea and large bronchi, thickening of the mucous membrane, sagging of the posterior (membranous) part of the trachea and bronchi into the lumen until the walls are in full contact. With bronchography, the expansion of the trachea and bronchi, their deformation and unevenness of the walls are clearly visible. With cinematography, it is also possible to reveal the collapse of the walls of the trachea and bronchi during breathing, to clearly establish the extent of the lesion.

Differential diagnosis is carried out with secondary tracheobronchomalacia, which develops as a result of compression of the walls of the trachea and bronchi with vascular malformations detected by angiography: double aortic arch, improper location of the pulmonary and subclavian arteries, etc. Treatment of tracheobronchomegaly is determined by the severity of clinical manifestations.

In the absence of attacks of hypoxia, symptomatic treatment is carried out aimed at improving the drainage function of the bronchi, preventing or eliminating inflammation in the lungs and bronchi. (drainage position, antibiotic therapy, alkaline inhalation, breathing exercises). With age, the patient's condition may improve - there is full compensation.

With pronounced symptoms of the disease and respiratory failure, they resort to surgical treatment - strengthening and fixing the posterior wall of the trachea and bronchi with the help of costal cartilage or artificial material. This gives good results with limited lesion. With secondary tracheobronchomalacia, surgical treatment is aimed at eliminating compression and strengthening the pathologically altered wall of the trachea and bronchi; sometimes limited resection of the affected areas of the trachea and bronchi is performed.

With congenital stenosis of the trachea and bronchi, their lumen is usually narrowed throughout the tracheobronchial tree (total stenosis); limited congenital stenoses are extremely rare. The trachea and bronchi are usually represented by closed cartilaginous rings. Clinical symptoms are most pronounced with total tracheal and bronchial stenosis. Often in infancy and even during the neonatal period. Noisy breathing, symptoms of respiratory failure, hypoxia may appear. Symptoms are worse when the child is anxious.

Stenoses of the trachea and bronchi often lead to the development of tracheobronchitis, accompanied by hypoventilation and atelectasis of certain parts of the lung. Differential diagnostics is primarily carried out with tracheal and B. stenosis, caused by their compression from the outside by abnormal vessels. In the case of compression of the trachea or bronchi from the outside, during bronchoscopy, good patency of this area and its decline when the bronchoscope is withdrawn, the transmission pulsation of abnormal vessels are determined.

To clarify the diagnosis, angiography is shown, and in the absence of respiratory disorders, bronchography. Surgical treatment is carried out for severe respiratory disorders, regardless of the child's age. With limited stenosis of the trachea and bronchi, the operation consists in resection of the narrowed area followed by the imposition of an anastomosis; the prognosis is favorable. With total stenosis, the trachea and bronchi are dissected along the entire length and costal cartilage or artificial plastic material is sewn in; the forecast is serious.

The tracheal bronchus is more often an accessory bronchus extending above the tracheal bifurcation; ends blindly, forming a diverticulum, or ventilates an additional (tracheal) lobule of the lung, which is often hypoplastic. In the accessory bronchus and hypoplastic lung tissue, a chronic inflammatory process can occur with the development of bronchiectasis. The diagnosis is made by bronchological examination. Tracheal bronchus can also be detected with X-ray tomography and computed tomography. In the case of a recurrent suppurative process, the reaction of the accessory bronchus and hypoplastic lung tissue is shown. The forecast is favorable.

Damage to large bronchi occurs simultaneously with damage to the trachea in severe closed injuries and penetrating chest wounds. B.'s damages are possible during bronchoscopy. Clinically, damage to the trachea and large bronchi is manifested by sharp respiratory disorders: shortness of breath, cyanosis, rapidly growing subcutaneous emphysema of the neck, head and trunk. With extrapleural injuries, signs of mediastinal and subcutaneous emphysema dominate; with intrapleural injuries, symptoms of tension pneumothorax, lung collapse and hemorrhage into the pleural cavity occur. Injuries and ruptures of the trachea, bronchi and fractures of their cartilage are often combined with ruptures and injuries of large blood vessels, which is accompanied by massive blood loss, and often death of the victims at the scene or during transportation to a medical institution.

In case of fracture of the cartilaginous rings of the bronchus without rupture of their walls, symptoms of damage to the chest and compression of the lung prevail: sharp pain in the chest, shortness of breath, hemoptysis. X-ray signs of tracheal and bronchial damage are the detection of gas and fluid in the pleural cavity, mediastinal displacement, horizontal fluid levels, or shadowing in mediastinal hemorrhages; fracture of the cartilaginous rings of the bronchus is manifested by homogeneous shading of the lung on the side of the injury and displacement of the mediastinum in this direction. In difficult cases, bronchial damage is confirmed by bronchoscopy. Treatment includes puncture and drainage of the pleural cavity, antibacterial and symptomatic therapy. With a large defect in the chest, ongoing pulmonary bleeding, surgical treatment is indicated. The damaged large B. and the vessels are sutured. The prognosis is favorable in most cases.

Diseases:

The most common are acute and chronic bronchitis and bronchiolitis, bronchiectasis, bronchial asthma. The bronchi can be affected with tuberculosis, mycoses (for example, with aspergillosis), scleroma. Perhaps the defeat of the bronchi with some helminthiasis - for example, with ascariasis sometimes there is bronchospasm, bronchopneumonia. Occupational bronchus diseases include dusty and toxic bronchitis, occupational bronchial asthma.

Bronchoconstriction:

Manifestations or complications of various pathological processes in the bronchopulmonary system can be bronchoconstriction, broncholithiasis, bronchial fistula. Bronchoconstriction is a narrowing of the lumen of the bronchus due to pathological changes in its wall or compression from the outside. Allocate congenital and acquired bronchial stenosis.

The causes of acquired stenosis of segmental and larger bronchi are diverse: malignant and benign tumors of the bronchi; active tuberculosis bronchus; post-tuberculous and post-traumatic cicatricial changes in the bronchi: compression of the walls of the bronchi by formations of the mediastinum, enlarged lymph nodes (with tuberculosis, sarcoidosis, lymphogranulomatosis, etc.). Persistent stenosis of the bronchus rarely develops on the basis of a nonspecific inflammatory process, which. as a rule, it does not apply to the supporting elements of B. and does not destroy them, Conditionally distinguish 3 degrees of bronchoconstriction: I - narrowing of the lumen of the bronchus by 1/2; II - narrowing by 2/3; III - narrowing by more than 2/3. Grade I bronchoconstriction is not accompanied by serious functional impairments. With bronchoconstriction of II and III degrees, violations of the air-conducting and drainage functions of the bronchi are noted.

With a sharp bronchoconstriction, a valve mechanism of ventilation disorders can develop, in which B. remains passable on inhalation and overlaps on exhalation, as a result of which a part of the lung distal to the stenosis begins to swell. In the area of \u200b\u200bimpaired ventilation of the lung, an inflammatory process often develops. Patients with stenosis of a large (main, lobar, segmental) bronchus II and III degree usually complain of a cough, sometimes paroxysmal, painful, not bringing relief. On auscultation over the affected area, hard breathing is heard.

With stenosis of the main B., stenotic (noisy with an abundance of wheezing on inhalation) breathing is possible. Chest X-ray allows detecting secondary changes in the lung distal to bronchoconstriction: areas of hypoventilation, atelectasis, emphysema, foci of inflammation, as well as signs of diseases leading to bronchoconstriction - a shadow of a tumor, enlarged lymph nodes, etc. Assessment of the state of the bronchi at the site of stenosis is carried out according to the data tomography and bronchography. Bronchoscopy allows you to clarify the localization, the severity of the narrowing, and the biopsy of the bronchial mucosa - the etiology of the disease. Small bronchial stenosis is often not clinically manifested.

In areas of the lung that are not sufficiently ventilated through the stenotic bronchus, recurrent inflammatory processes may occur. Treatment of cicatricial stenosis of large bronchi, as a rule, is operative: excision of the narrowed area of \u200b\u200bthe bronchus and the imposition of an interbronchial anastomosis; according to indications - removal of a part of the lung, aerated by a narrowed bronchus, or pulmonectomy. For the treatment of cicatricial stenosis of the bronchus, methods of endobronchial laser surgery are also used. With secondary (compression) narrowing of the bronchus of the pathological formation, which caused its compression, is removed. The therapy of the underlying disease leading to the development of stenosis and its complications is indicated. The prognosis of acquired bronchial stenosis after radical surgery is favorable.

Broncholithiasis:

Broncholithiasis is a pathological condition characterized by the presence of one or more calcareous stones (broncholitis) in the lumen of the bronchi. More often they enter the bronchus as a result of the penetration of petrification from the tracheobronchial lymph nodes in patients with tuberculosis. It is extremely rare that broncholitis is formed endobronchially by calcification of lumps of mucus, colonies of fungi (for example, of the genus Candida), etc. Broncholitis is more often localized in lobar or segmental bronchi. Patients have persistent cough, chest pain, hemoptysis, and sometimes pulmonary hemorrhage.

The diagnosis is made on the basis of X-ray and bronchoscopic data. In most patients, bronchodilator can be removed with forceps through the tube of the bronchoscope. If this is not possible, surgical treatment is performed (for example, resection of a lobe or segment of the lung).

Tumors:

Bronchial tumors arise from various elements of the bronchial wall and can be benign or malignant.

Among benign tumors of the bronchus are epithelial (adenoma, papilloma), mesenchymal (cavernous and capillary hemangiomas, hemangioendothelioma), neurogenic (neurinoma, neurofibroma, carcinoid), connective tissue (fibroma, lipoma, chondroma), muscle background of B.'s malformation (hamartoma, teratoma). Benign bronchus tumors account for 7-10% of all primary lung neoplasms. More often observed in persons under the age of 50. Adenomas are more common in women, hamartomas in men. Benign tumors grow slowly, doubling of their size occurs within 3-4 years or more.

Tumors can grow both endobronchial and peribronchial. Tumors associated with the wall of the main, lobar and segmental bronchi are called central; outgoing from the bronchi of a smaller caliber - peripheral. Clinical manifestations depend on the localization of the tumor relative to the bronchial lumen and on the caliber of the affected bronchus. Diagnostics, incl. differential, based on the data of X-ray examination of the lungs, bronchoscopy and biopsy. Treatment is usually prompt. The prognosis is favorable in most cases.

Bronchial adenoma:

The most common are adenoma and hamartoma of the bronchi. Adenoma bronchus refers to central tumors. By structure, mucoid, mucoepidermoid, cylindromatous (cilivdroma) and carcinoid adenoma are distinguished. The adenoma is located in the lumen of a large bronchus on a pedicle or on a broad base, has a red or gray-red color. The endobronchial growth of adenoma may be accompanied by a more significant peribronchial growth. At the onset of the disease, there may be a dry cough, hemoptysis, then, as bronchial patency is impaired, the cough intensifies, sputum appears (mucopurulent, then purulent), hemoptysis becomes more frequent.

Obturation of the bronchus with a tumor leads to atelectasis of the lobe or the entire lung, the development of secondary inflammatory changes in the lung tissue with an outcome in chronic suppuration. The course of the disease is slow, characterized by alternating periods of relative well-being and deterioration. X-ray examination reveals hypoventilation, atelectasis of the lobe or the entire lung, with tomography - a node in the lumen of the bronchus. The final diagnosis is confirmed by the results of bronchoscopy and biopsy. Surgical treatment - removal of the affected lobe or the entire lung, in some cases, a fenestrated or circular resection of the bronchus, removal of the tumor during bronchotomy is possible. The forecast is favorable.

Gamartoma:

Hamartoma is a non-epithelial tumor that develops against the background of bronchial malformation due to the proliferation of any tissue of the bronchial wall, more often cartilage (chondrogamartoma). The tumor is located, as a rule, in the peripheral parts of the bronchial tree, more often in the lower right lobe. In rare cases, a tumor develops in the lumen of large bronchi. The course is long and usually asymptomatic, occasionally hemoptysis is possible.

X-ray examination in the lung reveals a round, well-defined, dense, homogeneous shadow with calcareous inclusions in the center against the background of unchanged surrounding lung tissue. More often the tumors are single, rarely multiple. Treatment is usually prompt - exfoliation of the tumor. In the absence of tumor growth, dynamic observation is possible. In the case of localization of a tumor in large B., the same operations are performed as in bronchial adenoma. The forecast is favorable.

Among malignant tumors of the bronchus, bronchogenic cancer is most common. It is extremely rare that bronchus sarcoma is observed, the clinical and radiological symptoms of which do not differ significantly from those in bronchogenic cancer, the diagnosis can be clarified only with histological examination.

Operations:

Typical operations on large bronchi (main and lobar) are suturing of the bronchus wound, restoration of the bronchus in case of rupture, bronchotomy, fenestrated and circular bronchus resection, bronchial stump reamputation. All operations on the bronchi are performed under endotracheal anesthesia with artificial ventilation. Surgical access, as a rule, is a lateral or posterolateral thoracotomy. Some operations on the bronchi are performed using a trans-sternal approach. For suturing the bronchi, large atraumatic needles with thin suture material are used. The best is an absorbable synthetic material - vicryl.

Suturing of a bronchial wound is usually performed in a direction transverse to the bronchial axis - in order to avoid narrowing its lumen. Sutures are passed through all layers of the bronchial wall. When restoring the bronchi in the case of a circular rupture, it is necessary to pre-excise the non-viable, blood-soaked edges of the bronchial stumps. Then, an anastomosis is applied between both bronchial stumps. It is important to ensure tightness along the anastomotic line to prevent air leakage.

Bronchotomy - opening the lumen of the bronchus with a longitudinal, oblique or transverse incision for diagnostic or therapeutic purposes. With bronchotomy, you can examine the bronchi from the inside, take material for an urgent histological examination, remove a foreign body or tumor.

Finished or circular resection of the bronchi as an independent operation is performed mainly for benign tumors and cicatricial stenosis of the bronchi. In patients with lung cancer, these operations are usually performed together with a lung resection (usually with a lobectomy). Bronchial resection in a number of patients with lung cancer makes it possible to increase the radicality of the operation without expanding the volume of the removed lung tissue. The defect in the bronchi is sutured after final resection, and after circular resection, the airway is restored by applying a bronchial anastomosis end-to-end.

Reamputation (re-excision) of the bronchus stump with its repeated suturing is used to eliminate bronchial fistula after pneumonectomy or lobectomy. Before re-amputation, the stump must be removed from the scar tissue.

The methods of endobronchial surgery (surgical interventions during bronchoscopy) with the use of electro-, cryo- and laser effects are becoming more and more widespread.

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