Dikain: instructions for the use of eye drops. Dikain instructions for use Dikain eye drops

Dikain is a local anesthetic that is significantly superior in activity to cocaine and novocaine, but more toxic. The drug is well absorbed into the systemic circulation through the mucous membranes.

Release form and composition

Dikain is produced in the form of eye films (0.75 mg) and substance-powder (1 g) in dispenser cases of 30 pieces or in dark glass jars.

The active active ingredient of the drug is tetracaine.

Indications for use

According to the instructions, Dikain is used for superficial anesthesia during short-term manipulations and operations in ophthalmic and otorhinolaryngological practice, including when removing superficial foreign bodies, gonioscopy, outpatient surgical interventions, tonometry and other diagnostic procedures.

Contraindications

The use of Dikain is contraindicated in case of increased individual sensitivity to tetracaine, para-aminobenzoic acid and its derivatives and other local anesthetics from the ester group.

The drug is not used for inflammation or damage to mucous membranes, including corneal erosion or epithelial damage.

Dikain is not prescribed for children under the age of 10 years.

Method of administration and dosage

In ophthalmology, the drug is used in the form of a 0.1% transparent colorless or slightly colored solution. The dose of Dikain depends on the type of procedure being performed. So, when measuring intraocular pressure, 1 drop is prescribed twice with an interval of several minutes. Anesthesia develops 1-2 minutes after instillation.

For surgical interventions and removal of foreign bodies, 0.25%, 0.5%, 1% or 2% Dikain solution is used. The dose of the drug is 2-3 drops. Severe anesthesia develops in 1-2 minutes.

As a rule, in ophthalmology, a 0.5% solution is sufficient for anesthesia during surgical interventions. To enhance and lengthen the effect of anesthesia, 3-5 drops of 0.1% adrenaline solution are added to 10 ml of Dikain. If long-term pain relief is required, eye films are used.

In otorhinolaryngological practice, Dikain is used for some surgical interventions, for example, with a puncture maxillary sinus, cronchotomy, middle ear surgery and removal of polyps. Since the drug is rapidly absorbed by the mucous membranes of the respiratory system, caution should be exercised when using it and the patient's condition should be carefully monitored.

In children over 10 years old, the dose of Dikain, according to the instructions, is no more than 1-2 ml, and the concentration of the solution is from 0.5 to 1%. The dosage for adults should not exceed 3 ml of a 1% solution. The use of Dikain 2% or 3% is possible only for serious indications and in case of emergency. The maximum allowable for anesthesia of the upper respiratory tract the dose of the drug for adults is 0.09 g once (which corresponds to 3 ml of a solution of 3% concentration).

Side effects

Dikain's local side effects include:

• Allergic contact dermatitis;
• Pain and swelling at the site of application;
• Burning sensation;
• Irritation of mucous membranes.

With prolonged use of Dikain in ophthalmology, persistent corneal opacity, keratitis, slowing of epithelialization and the formation of scars on the cornea of \u200b\u200bthe eye with subsequent loss of visual acuity are possible.

From system side effects it is worth noting visual impairment, cyanosis, arrhythmia, excitation of the central nervous system and anaphylactic shock.

special instructions

Solutions with a concentration of 2% or more can cause damage to the corneal epithelium and significant vasodilation of the outer membrane of the eye.

Dikain is prescribed with caution to patients with AV blockade, cardiac arrhythmias, shock, and low blood cholinesterase levels. When performing local spinal anesthesia, blood pressure must be monitored.

Syringes and instruments in contact with the drug should not contain alkaline residues, as this will form an insoluble base.

Analogs

Dikain's analogs include drugs such as:

• Articaine;
• Tetracaine hydrochloride;
• Decicaine;
• Interkain;
• Pantocaine;
• Medicain;
• Rexocaine;
• Fonkain;
• Felikain.

Terms and conditions of storage

The drug should be stored in a dry place, out of reach of children, at room temperature. The powder should be kept in an airtight, well-sealed container. Dikain's shelf life is 2 years.

Dikain drops include a 0.3% solution beta tetracaine... Additional substances: sodium chloride, water.

There are other concentrations of the solution. tetracaine depending on the manufacturer.

A clear, colorless, odorless solution.

The solution is available in vials of 10 and 5 ml.

Local anesthetic action

Pharmacodynamics

Dikain's solution is a local pain relieverfor surface anesthesia. Blocks sodium channels, which prevents the emergence of impulses in the sensitive nerve endings and the conduction of impulses along them.

The effect occurs 30-90 seconds after application to the mucous membranes and lasts for 20 minutes.

It is quickly and fully absorbed through the mucous membranes (the rate of absorption depends on the area of \u200b\u200badministration and dosage). The reaction with plasma proteins is very high. Completely hydrolyzed in plasma due to cholinesterase within an hour and a half with products PABA-containing compounds... Partially metabolized in the liver in the same way. It is excreted in urine and bile, partially being recirculated in the liver and intestines.

The use of Dikain is justified for the purpose of local surface anesthesia:

• for short operations and manipulations in ophthalmology (outpatient surgical operations, removal of foreign bodies, tonometry, gonioscopy, other diagnostic procedures) and otorhinolaryngology;
• for spinal anesthesia if there are contraindications to the introduction of local amide anesthetics;
• for pain relief of the larynx region during bronchography, intubation, esophago- and bronchoscopy;
• for pain relief of the urethra before catheterization.

Side effects

• Local phenomena: contact dermatitis, irritation of the mucous membranes, burning, edema and pain at the site of application; with prolonged use, the development keratitis, opacity and scarring of the cornea, delayed epithelialization.
• Systemic phenomena: visual impairment, nervous excitement, cyanosis, anaphylactic shock, arrhythmia.

Dikain, application instruction (Way and dosage)

The drug is used primarily for terminal anesthesia and very rarely for epidural anesthesia. The substance is extremely toxic, therefore it is not suitable for infiltration and local anesthesia. The highest dose for topical use is 0.1 grams.

IN ophthalmic practice the medicine is used in an amount of 2-3 drops. The maximum analgesic effect develops after 1-2 minutes. When carrying out eye interventions, a 0.5% solution of the agent is usually enough to achieve the desired anesthetic effect. To prolong and enhance the effect, you can add to Dikain Epinephrine (0.1% solution) in the following ratio: 1 drop Epinephrine for 2 ml of solution tetracaine... For pain relief with study of intraocular pressure allowed to use a 0.1% solution.

IN otolaryngology usually apply 0.25-0.5% solutions. Adult patients, at the discretion of the doctor, are allowed to prescribe up to 3 ml of a solution with a concentration of 1%. 2-3% solutions are used only when absolutely necessary. Lubrication of the laryngopharynx is performed slowly, maintaining intervals and observing the patient's condition. To reduce the reaction to the drug 40-60 minutes before anesthesia, the patient is given 0.1 gram Barbamila... If there are no contraindications for vasoconstrictor drugs, then it is allowed to add to Dikain Epinephrine in the above proportion. The tampon is impregnated with a solution and the surface of the mucous membrane is lubricated. Forbidden on long time leave a tampon in the nasal cavity.

Using Dikain when carrying out epidural anesthesia requires special care. To do this, a 0.25-0.3% solution is prepared under aseptic conditions and sterilized by boiling for 30 minutes, then a 0.1% solution is added to it Epinephrine at the rate of 1: 100. The medicine is injected in stages, slowly - 16-20 ml, observing five-minute breaks between injections.

For pain relief of the urinary tract apply up to 10 ml of 0.1% Dikain.

Overdose signs: general weakness, dizziness, agitation, muscular tremor, anxiety, convulsions, collapse, breathing disorder, nausea, methemoglobinemia, coma, vomiting, AV block.

Overdose treatment: immediate removal of the drug from the skin and mucous membranes; with oppression of the respiratory process shown artificial lung ventilation and oxygen therapy, for convulsions, enter Diazepam or barbiturates, at collapse intravenous blood substitutes are used ( Hemodez, saline solutions, drugs dextran) and vasoconstrictors, at methemoglobinemia - intravenously Methylene blue at the rate of 1-2 mg / kg or orally 100-200 mg vitamin C.

Dikain is able to weaken the action sulfa drugs.

On prescription.

Store in a cool place. Keep out of the reach of children.

Two years.

If possible, then Dikain should be replaced Novocainas it is less toxic. Solutions containing more than 2% tetracaine capable of damaging epithelium cornea and over-dilate the arteries of the conjunctiva. In ophthalmology this medicine it is not recommended to use it for a long time or often.

It is forbidden to administer the drug subarachnoid.

When performing spinal anesthesia using Dikain, you need to constantly monitor arterial pressure.

The drug is prescribed with caution in patients with reduced levels cholinesterase in blood, AV blockade, arrhythmias, shock.

Medical instruments in contact with Dikain should not have residues alkalis, since as a result of the interaction, an insoluble precipitate is formed.

Novocaine, Ultracaine, Lidocaine, Anestezin, Felicaine, Anetaine, Decicaine, Ametocaine, Intercaine, Medicaine, Rexocaine, Pantocaine, Foncaine, Intercaine.

It is forbidden to use the drug in children under 10 years of age.

It is allowed to use during the indicated periods only in exceptional cases with strict indications.

At the moment, medical professionals are trying to abandon the use of this drug in their practice because of its high toxicity and the availability of more affordable and safe analogues.

If it is necessary to use the drug, the doctor usually writes out a prescription for Dikain. Dikain in Latin usually looks like Tetracaini hydrochloridum.

Due to the above in the section " special instructions»Disadvantages and availability of more affordable and this tool is almost not on sale. No price data available.

Dikain (Dikain (beta form) solution 0.3% ( eye drops)) Is a local anesthetic drug used in ophthalmology.

Dosage form - eye drops: slightly colored or colorless, transparent or slightly opalescent solution (in bottles of 5 (with a dropper) or 10 ml, 1 bottle in a cardboard box).

The preparation contains leocaine, sodium chloride, purified water.

Dikain is a local pain reliever used for surface anesthesia. The substance provides blocking of sodium channels, preventing the occurrence of impulses in sensitive nerve endings and their conduction in nerve tissues.

The drug takes effect 30–90 seconds after application to the mucous membranes. The duration of the action is 20 minutes.

The Dikain solution is rapidly and almost completely absorbed through the mucous membranes. The rate of absorption is determined by the dosage of the drug. The degree of its binding to plasma proteins is quite high. The substance is completely hydrolyzed in plasma with the participation of cholinesterase for 1.5 hours, forming PABA-containing compounds. In the same way, dicaine is partially metabolized in the liver and excreted mainly in the bile and through the kidneys, partially being recirculated in the intestines and liver.

Dikain is prescribed to adults for pain relief during short-term surgical interventions on the anterior segment of the eyeball.

A contraindication to the use of the drug is the presence of hypersensitivity to its components.

Dikain is used in the form of instillations of 1-2 drops immediately before surgery. If necessary, during the operation (depending on the patient's condition and duration of the operation), you can additionally instill 1-2 drops.

After using Dikain, a short-term burning sensation and mild allergic reactions may develop.

Overdose symptoms are:

• agitation and anxiety;
• muscle tremor;
• convulsive activity;
• dizziness;
• general weakness;
• nausea and vomiting;
• breathing disorder;
• collapse;
• coma;
• AV block;
• methemoglobinemia.

When these signs appear, the drug is immediately removed from the skin and mucous membranes. When the respiratory center is inhibited, oxygen therapy and mechanical ventilation are recommended. With convulsive activity, barbiturates or diazepam are used. In case of collapse, vasoconstrictors and blood substitutes (dextran preparations, saline solutions, hemodesis) are injected intravenously. In case of methemoglobinemia, methylene blue is administered intravenously at a dose of 1-2 mg / kg, or oral administration vitamin C in the amount of 100-200 mg.

Dikain does not aggravate the course of pathological processes.

The use of Dikain during these periods is allowed only in exceptional cases as prescribed by a doctor and in the presence of strict indications.

There are no data on the interaction of the Dikain solution with other drugs.

Dikain's analogs are: Novocaine, Ultracaine, Lidocaine, Anestezin, Felikaine, Anetaine, Decicaine, Ametokaine, Interkaine, Medikaine, Rexocaine, Pantokaine, Foncaine.

Store in a cool place out of reach of children.

Shelf life is 2 years.

Dispensed by prescription.

According to reviews, Dikain is practically not used by medical professionals in practice due to its high toxicity and the development of safer and more inexpensive analogues. If it is necessary to prescribe a drug, the doctor must write a prescription.

The price of Dikain is unknown because medicine due to the toxic effect on the body and the development of more effective and affordable analogs, it is not commercially available.

Name: Dikain

Name:

Dikain (Dicainum) Indications for use:

Dikain is used only for surface anesthesia (pain relief).

pharmachologic effect:

Strong local anesthetic. In activity, it is significantly superior to novocaine and cocaine, but more toxic. It is well absorbed through the mucous membranes.

Dikain method of administration and doses:

In ophthalmic practice, it is used in the form of a 0.1% solution when measuring intraocular pressure (one drop 2 times with an interval of 1-2 minutes). Anesthesia usually develops in 1-2 minutes. When removing foreign bodies and surgical interventions, 2-3 drops of 0.25-0.5-1% or 2% solution are used. In 1-2 minutes, severe anesthesia develops. It should be borne in mind that solutions containing more than 2% dicaine can cause damage to the epithelium (outer layer) of the cornea (transparent membrane of the eye) and significant dilation of the vessels of the conjunctiva (outer membrane of the eye). Usually, for anesthesia during eye surgery, a 0.5% solution is sufficient. To lengthen and enhance the anesthetic effect, add 0.1% adrenaline solution (3-5 drops per 10 ml of dicaine).

With keratitis (inflammation of the cornea / transparent membrane of the eye /), dicaine is not used.

In ophthalmic practice, if long-term anesthesia is required, eye films with dicain are used. Each film contains 0.00075 g (0.75 mg) dicaine.

Dikain is also used for surface anesthesia in otorhinolaryngological practice during certain surgical interventions (maxillary sinus puncture, removal of polyps, conchotomy / removal of the inferior or middle turbinate /, middle ear surgery). Due to the rapid absorption of dicaine by the mucous membranes of the respiratory tract, great care should be taken when using it and carefully monitor the patient's condition. Children under 10 years old are not anesthetized with dicain. In older children, no more than 1-2 ml of a 0.5-1% solution is used, in adults, up to 3 ml of a 1% solution (sometimes 0.25-0.5% solution is sufficient) and only if absolutely necessary - 2% or 3% solution. To a solution of dicaine (in the absence of contraindications to the use of vasoconstrictor substances) add 1 drop of 0.1% solution of epinephrine hydrochloride per 1-2 ml of dicaine. Higher doses of dicaine for adults with anesthesia of the upper respiratory tract - 0.09 g one-time (3 ml of 3% solution).

Dikain contraindications:

Age up to 10 years, the general serious condition of the sick. When working with dicain, instruments and syringes should not contain alkali residues. Dikain precipitates in the presence of alkali.

Dikain side effects:

The drug is very toxic, care must be taken when using it.

Release form:

Eye powder and films with dicaine, 30 pcs. in dispensers.

Synonyms:

Tetracaine hydrochloride, Ametokaine, Anetaine, Decicaine, Felicaine, Foncaine, Intercaine, Medicaine, Pantocaine, Rexocaine.

Storage conditions:

List A. In a well-closed container.

Attention!

Before using the medication

"Dikain" it is necessary to consult a doctor.

The instruction is provided solely for acquaintance with "

Dikain ».

Instructions for use:

Release form and composition

Pharmacodynamics and pharmacokinetics

Indications for use

Contraindications

Instructions for use

Side effects

Overdose

special instructions

Application in children

Pregnancy and lactation

Drug interactions

Terms and conditions of storage

Terms of dispensing from pharmacies

Dikain (powder g)

Description active substance (INN) Tetracaine * (Tetracaine *)

Pharmacology: pharmachologic effect - local anesthetic ... Blocks sensitive nerve endings and conductors; penetrates the membrane of nerve cells, disrupts the transmembrane transport of ions (especially sodium), reduces the flow of impulses in the central nervous system; dilates blood vessels.

Indications: Local (superficial and spinal) anesthesia.

Contraindications: Hypersensitivity (including to other local anesthetics of the ether group or PABA and its derivatives), severe somatic diseases, childhood (up to 10 years old).

Application during pregnancy and lactation: Perhaps in exceptional cases, if the expected effect of therapy outweighs the potential risk to the fetus and newborn.

Side effects: When topical application: allergic contact dermatitis, burning sensation, swelling and pain in the area of \u200b\u200bapplication; with prolonged use - keratitis, persistent corneal opacity, scarring on the cornea with loss of visual acuity, delayed epithelialization.

When injected: CNS excitement, depression, nervousness, dizziness, blurred vision, drowsiness, tremor, convulsions, loss of consciousness, cardiovascular failure, changes in blood pressure (usually hypotension), cardiac arrest, respiratory distress, nausea, vomiting, chills, narrowing pupils, tinnitus, idiosyncrasy or decreased tolerance, urticaria, anaphylactic shock.

Interaction: Reduces the antibacterial activity of sulfa drugs. Vasoconstrictor agents prolong the effect and reduce toxicity.

Overdose: Symptoms: dizziness, general weakness, cyanosis, agitation, anxiety, muscle tremor, convulsions, respiratory failure, collapse, methemoglobinemia, nausea, vomiting, coma, AV blockade.

Treatment: removal from the skin and mucous membranes, gastric lavage (through a tube) with activated carbon, the appointment of saline laxatives; in case of respiratory depression - mechanical ventilation and oxygen therapy, collapse - intravenous administration of blood substitutes (saline solutions, hemodez, polyglucin), the use of vasoconstrictors (preferably stimulating the myocardium), convulsions - diazepam or short-acting barbiturates (intravenous), methemoglobinemia - 1- 2 mg / kg methylene blue (i.v.) or 100-200 mg ascorbic acid inside.

Method of administration and dosage: For surface anesthesia - 0.05-1% (if necessary 2-3%) solution; in children over 10 years old - no more than 1-2 ml of 0.5-1% solution, in adults - up to 3 ml of 1% solution. The highest dose for adults is 3 ml of a 3% solution.

For epidural anesthesia - 5 ml of 0.3% solution 3-4 times at intervals of 5 minutes.

Precautions: Do not apply to large areas of damaged skin (risk of absorption and systemic toxicity). In ophthalmology, it is not recommended to use it for a long time or often (possible damage to the cornea). Use with caution in patients with reduced levels of cholinesterase in blood plasma, cardiac arrhythmias, AV blockade, shock. Spinal anesthesia requires monitoring of blood pressure.

Special instructions: Instruments and syringes in contact with tetracaine must not contain alkali residues (forms an insoluble base).

For anesthesia of the upper respiratory tract WFD-0.09 (3ml-3% solution once)

For epidural anesthesia VFD-0.075 (25ml-0.3% solution once)

Name: Dikain

Name: Dikain (Dicainum)

Indications for use:
Dikain is used only for surface anesthesia (pain relief).

Pharmachologic effect:
Strong local anesthetic. In activity, it is significantly superior to novocaine and cocaine, but more toxic. It is well absorbed through the mucous membranes.

Dikain method of administration and doses:
In ophthalmic practice, it is used in the form of a 0.1% solution when measuring intraocular pressure (one drop 2 times with an interval of 1-2 minutes). Anesthesia usually develops in 1-2 minutes. When removing foreign bodies and surgical interventions, 2-3 drops of 0.25-0.5-1% or 2% solution are used. In 1-2 minutes, severe anesthesia develops. It should be borne in mind that solutions containing more than 2% dicaine can cause damage to the epithelium (outer layer) of the cornea (transparent membrane of the eye) and significant dilation of the vessels of the conjunctiva (outer membrane of the eye). Usually, for anesthesia during eye surgery, a 0.5% solution is sufficient. To lengthen and enhance the anesthetic effect, add 0.1% adrenaline solution (3-5 drops per 10 ml of dicaine).
With keratitis (inflammation of the cornea / transparent membrane of the eye /), dicaine is not used.
In ophthalmic practice, if long-term anesthesia is required, eye films with dicain are used. Each film contains 0.00075 g (0.75 mg) dicaine.
Dikain is also used for surface anesthesia in otorhinolaryngological practice during certain surgical interventions (maxillary sinus puncture, removal of polyps, conchotomy / removal of the inferior or middle turbinate /, middle ear surgery). Due to the rapid absorption of dicaine by the mucous membranes of the respiratory tract, great care should be taken when using it and carefully monitor the patient's condition. Children under 10 years old are not anesthetized with dicain. In older children, no more than 1-2 ml of a 0.5-1% solution is used, in adults - up to 3 ml of a 1% solution (sometimes 0.25-0.5% solution is sufficient) and only if absolutely necessary - 2% or 3% solution. To the solution of dicaine (in the absence of contraindications to the use of vasoconstrictor substances) add 1 drop of 0.1% solution of epinephrine hydrochloride per 1-2 ml of dicaine. Higher doses of dicaine for adults with anesthesia of the upper respiratory tract - 0.09 g one-time (3 ml of 3% solution).

Dikain contraindications:
Age up to 10 years, the general serious condition of the sick. When working with dicain, instruments and syringes should not contain alkali residues. Dikain precipitates in the presence of alkali.

Dikain side effects:
The drug is very toxic, care must be taken when using it.

Release form:
Eye powder and films with dicaine, 30 pcs. in dispensers.

Synonyms:
Tetracaine hydrochloride, Ametokaine, Anetaine, Decicaine, Felicaine, Foncaine, Intercaine, Medicaine, Pantocaine, Rexocaine.

Storage conditions:
List A. In a well-closed container.

Attention!
Before using the medication "Dikain" it is necessary to consult a doctor.
The instruction is provided solely for acquaintance with " Dikain».

Dikain drops include a 0.3% solution beta tetracaine ... Additional substances: sodium chloride, water.

There are other concentrations of the solution. tetracaine depending on the manufacturer.

Release form

A clear, colorless, odorless solution.

The solution is available in vials of 10 and 5 ml.

pharmachologic effect

Local anesthetic action

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Dikain's solution is a local pain reliever for surface anesthesia. Blocks sodium channels, which prevents the emergence of impulses in the sensitive nerve endings and the conduction of impulses along them.

The effect occurs 30-90 seconds after application to the mucous membranes and lasts for 20 minutes.

Pharmacokinetics

It is quickly and fully absorbed through the mucous membranes (the rate of absorption depends on the area of \u200b\u200badministration and dosage). The reaction with plasma proteins is very high. Completely hydrolyzed in plasma due to cholinesterase within an hour and a half with products PABA-containing compounds ... Partially metabolized in the liver in the same way. It is excreted in urine and bile, partially being recirculated in the liver and intestines.

Indications for use

The use of Dikain is justified for the purpose of local surface anesthesia:

• for short operations and manipulations in ophthalmology (outpatient surgery, removal of foreign bodies, tonometry, gonioscopy , other diagnostic procedures) and otorhinolaryngology;
• for spinal anesthesia if there are contraindications to the introduction of local amide ;
• for pain relief of the larynx region during bronchography , intubation, esophago- and bronchoscopy ;
• for pain relief of the urethra before catheterization .

Contraindications

• to para-aminobenzoic acid , tetracaine and others anesthetics such as esters ;
• damage or inflammation of the mucous membranes in the area of \u200b\u200bintended application, including damage or erosion of the cornea.
• reception sulfa drugs ;
• children under 10 years of age;
• the drug is used with caution when AV blockade , shock, decrease in level cholinesterase in .

Side effects

• Local phenomena: contact , irritation of the mucous membranes, burning, and pain at the site of application; with prolonged use, development, opacity and formation of corneal scars, slowing of epithelialization are not excluded.
• Systemic phenomena: visual impairment, nervous excitement, cyanosis, anaphylactic shock, arrhythmia.

Dikain, application instruction (Way and dosage)

The drug is used primarily for terminal anesthesia and very rarely for epidural anesthesia. The substance is extremely toxic, therefore it is not suitable for infiltration and local anesthesia. The highest dose for topical use is 0.1 grams.

IN ophthalmic practice the medicine is used in an amount of 2-3 drops. The maximum analgesic effect develops after 1-2 minutes. When carrying out eye interventions, a 0.5% solution of the agent is usually enough to achieve the desired anesthetic effect. To prolong and enhance the effect, you can add to Dikain (0.1% solution) in the following ratio: 1 drop Epinephrine for 2 ml of solution tetracaine ... For pain relief with study of intraocular pressure allowed to use a 0.1% solution.

IN otolaryngology usually apply 0.25-0.5% solutions. Adult patients, at the discretion of the doctor, are allowed to prescribe up to 3 ml of a solution with a concentration of 1%. 2-3% solutions are used only when absolutely necessary. Lubrication of the laryngopharynx is performed slowly, maintaining intervals and observing the patient's condition. To reduce the reaction to the drug 40-60 minutes before anesthesia, the patient is given 0.1 gram Barbamila ... If there are no contraindications for vasoconstrictor drugs, then it is allowed to add to Dikain Epinephrine in the above proportion. The tampon is impregnated with a solution and the surface of the mucosa is lubricated. It is forbidden to leave a tampon in the nasal cavity for a long time.

Using Dikain when carrying out epidural anesthesia requires special care. To do this, a 0.25-0.3% solution is prepared under aseptic conditions and sterilized by boiling for 30 minutes, then a 0.1% solution is added to it Epinephrine at the rate of 1: 100. The medicine is injected in stages, slowly - 16-20 ml, observing five-minute breaks between injections.

For pain relief of the urinary tract apply up to 10 ml of 0.1% Dikain.

Overdose

Overdose signs: general weakness, agitation, muscular, restlessness, convulsions , collapse , breathing disorder, nausea, methemoglobinemia , vomiting, AV block .

Overdose treatment: immediate removal of the drug from the skin and mucous membranes; with oppression of the respiratory process shown artificial lung ventilation and oxygen therapy , with convulsions, enter or barbiturates , at collapse intravenous blood substitutes (, saline solutions, drugs dextran ) and vasoconstrictors , at methemoglobinemia - intravenously at the rate of 1–2 mg / kg or orally 100–200 mg.

Interaction

Dikain is able to weaken the action sulfa drugs .

Terms of sale

On prescription.

Storage conditions

Store in a cool place. Keep out of the reach of children.

Shelf life

Two years.

special instructions

If possible, Dikain should be replaced, since it is less toxic. Solutions containing more than 2% tetracaine can damage the cornea and over-dilate the arteries of the conjunctiva. In ophthalmology, this medicine is not recommended for long-term or frequent use.

It is forbidden to administer the drug subarachnoid.

When performing spinal anesthesia using Dikain, you need to constantly monitor.

The drug is prescribed with caution in patients with reduced levels cholinesterase in blood, AV blockade, arrhythmias, shock.

Medical instruments in contact with Dikain should not have residues alkalis , since as a result of the interaction, an insoluble precipitate is formed.

Analogs

Novocaine, Felicaine, Anetaine, Decicaine, Ametokaine, Intercaine, Medicaine, Rexocaine, Pantocaine, Foncaine, Intercaine.

For children

It is forbidden to use the drug in children under 10 years of age.

During pregnancy and lactation

It is allowed to use during the indicated periods only in exceptional cases with strict indications.