Properties of ascorbic acid with glucose. Ascorbic acid without sugar: instructions for use

Last updated description by manufacturer 31.07.1997

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Active substance:

ATX

Pharmacological group

Nosological classification (ICD-10)

Composition and form of release

1 ampoule with lyophilized powder for preparation of an injection solution contains 0.05 g of ascorbic acid, complete with water for injection, in 2 ml ampoules; the package contains 5 sets.

pharmachologic effect

pharmachologic effect - replenishing vitamin C deficiency.

Pharmacodynamics

Participates in the regulation of carbohydrate metabolism of redox processes, blood coagulability, capillary permeability, tissue regeneration, synthesis of steroid hormones, collagen, procollagen.

Indications of the drug Ascorbic acid with glucose

Avitaminosis and hypovitaminosis C; hemorrhagic diathesis, bleeding (nasal, pulmonary, hepatic, uterine, caused by radiation sickness); overdose of anticoagulants; infectious diseases and intoxication; Addison's disease, nephropathy of pregnancy; sluggish healing wounds and bone fractures; dystrophy; mental and physical stress.

Contraindications

Hypersensitivity.

Side effects

Depression of the function of the insular apparatus of the pancreas (with long-term use).

Method of administration and dosage

In / m, in / in, before administration, the lyophilized powder is dissolved in 1-2 ml of sterile water for injection, for adults - 1-3 ml of a 5% solution (2-6 ml of a 2.5% solution) per day; children - 1-2 ml of a 5% solution (2-4 ml of a 2.5% solution) per day.

Precautionary measures

It is prescribed with caution in case of increased blood clotting, thrombophlebitis, tendency to thrombosis, diabetes mellitus. It is necessary to monitor renal function and blood pressure, especially when large doses are prescribed.

Storage conditions of the drug Ascorbic acid with glucose

At a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life of the drug Ascorbic acid with glucose

lyophilisate for preparation of solution for intravenous and intramuscular injection 0.05 g - 2 years.

tablets 100 mg + 877 mg 100 mg + 877 - 1 year.

dragee 50 mg - 1.5 years.

Do not use after the expiration date printed on the package.

Instructions for medical use

Vitamin C with glucose
Instructions for medical use - RU No. LP-001199

Last modified date: 11.11.2011

Dosage form

Pills

Composition

1 tablet contains:

Active substance:

Excipients:

Calcium stearate - 10 mg, talc - 13 mg.

Description of the dosage form

The tablets are white, flat-cylindrical, round, chamfered and scored.

Pharmacological group

pharmachologic effect

Ascorbic acid plays an important role in the regulation of redox processes, carbohydrate metabolism, blood clotting processes, tissue regeneration, and helps to increase the body's resistance to infections.

Dextrose (glucose) is involved in various metabolic processes in the body.

Indications

Prevention and treatment of hypo- and avitaminosis (scurvy). Providing an increased need for vitamin C in the body during the period of intensive growth, pregnancy, breastfeeding, with intense physical and mental stress, stressful conditions, during the period of recovery after prolonged serious illness.

Contraindications

Hypersensitivity to the drug. Large doses should not be prescribed to patients with increased blood clotting, thrombophlebitis and a tendency to thrombosis; with diabetes mellitus and conditions accompanied by increased content blood glucose. Contraindicated in children under 6 years of age.

Carefully

Diabetes mellitus, deficiency of glucose-6-phosphate dehydrogenase; for use in high doses - hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, nephrourolithiasis.

Application during pregnancy and lactation

Ascorbic acid crosses the placental barrier. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid taken by a pregnant woman, and then the newborn may develop ascorbic disease as a withdrawal reaction. Therefore, during pregnancy, you should not take ascorbic acid in higher dosesunless the expected benefit outweighs the potential risk.

Ascorbic acid is released from breast milk... A mother's diet containing adequate amounts of ascorbic acid is sufficient to prevent deficiency in an infant. It is recommended that a nursing mother not exceed the maximum daily requirement for ascorbic acid, unless the expected benefit outweighs the potential risk.

Method of administration and dosage

The drug is taken orally after meals.

For prophylactic purposes, adults take ½ (50 mg) - 1 (100 mg) tablet, children from 6 to 18 years old - ½ (50 mg) tablets per day.

For medicinal purposes, adults ½ (50 mg) - 1 (100 mg) tablet 3-5 times a day, children ½ (50 mg) - 1 (100 mg) 2-3 times a day.

The timing of treatment depends on the nature and course of the disease.

During pregnancy and lactation, 3 tablets per day for 10-15 days, then 1 tablet per day.

Side effects

Allergic reactions, irritation of the mucous membrane of the gastrointestinal tract (nausea, vomiting, diarrhea, spasm of the gastrointestinal tract); inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria): when used in high doses - hyperoxaluria and nephrocalcinosis (oxalate).

Changes in laboratory parameters: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia.

Overdose

Symptoms: when using more than 1 g - headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, diarrhea, hyperacid gastritis, ulceration of the mucous membrane of the gastrointestinal tract, inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular apparatus kidney, moderate pollakiuria (when taking a dose of more than 600 mg / day).

Decreased capillary permeability (possible deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathies).

In the case of ingestion of a potentially toxic dose, they induce vomiting, in rare cases, they wash the stomach, prescribe activated carbon, laxatives (for example, isotonic sodium sulfate solution).

Interaction

Ascorbic acid: increases the concentration of benzylpenicillin and tetracyclines in the blood; at a dose of 1 g / day increases the bioavailability of ethinyl estradiol (including that which is part of oral contraceptives).

Improves the absorption of iron preparations in the intestine (converts ferric iron to ferrous); can increase the excretion of iron while used with deferoxamine.

Reduces the effectiveness of heparin and indirect anticoagulants.

Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drinking reduce absorption and absorption.

With simultaneous use with acetylsalicylic acid, urinary excretion of ascorbic acid increases and excretion decreases acetylsalicylic acid... Acetylsalicylic acid reduces the absorption of ascorbic acid by about 30%. Increases the risk of crystalluria when treated with salicylates and sulfonamides short acting, slows down the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), reduces the concentration in the blood of oral contraceptives. Increases the total ethanol clearance, which in turn reduces the concentration of ascorbic acid in the body.

Medicines of the quinoline series, calcium chloride, salicylates, glucocorticosteroids, with prolonged use, deplete the reserves of ascorbic acid. With simultaneous use reduces chronotropic action isoprenaline. With prolonged use or use in high doses, the interaction of disulfiram-ethanol may be disrupted.

In high doses, it increases the excretion of mexiletine by the kidneys.

Barbiturates and primidone increase the excretion of ascorbic acid in the urine. Reduces therapeutic action antipsychotic drugs (neuroleptics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.

special instructions

Due to the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor renal function and blood pressure.

With prolonged use of large doses, it is possible to suppress the function of the insular apparatus of the pancreas, therefore, it must be regularly monitored during treatment.

In patients with an increased iron content in the body, ascorbic acid should be used in minimal doses.

The administration of ascorbic acid to patients with rapidly proliferating and intensely metastatic tumors can aggravate the process.

Ascorbic acid as a reducing agent can distort the results of various laboratory tests (blood glucose, bilirubin, hepatic transaminase and lactate dehydrogenase activity).

Information about possible impact medicinal product for medical use on the ability to drive vehicles, mechanisms

Does not affect the ability to drive vehicles and work with other mechanical vehicles.

Release form

Tablets (100 mg + 877 mg).

On 10 tablets in a blister strip packaging or in a blister strip packaging. 1, 2, 5 contour cell or contour non-cell packaging with instructions for use are placed in a pack. Contoured non-cell packages are placed in a group package with an equal number of instructions for use.

Storage conditions

In a dark place at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life

Do not use after the expiration date.

Terms of dispensing from pharmacies

LS-000073 from 2012-05-18

Synonyms for nosological groups

ICD-10 headingSynonyms of diseases according to ICD-10
E54 Deficiency of ascorbic acid [vitamin C]Avitaminosis C
Vitamin C vitamin deficiency
Avitaminosis C
Hypovitaminosis C
Vitamin C hypovitaminosis
Hypovitaminosis C
Vitamin C deficiency
Additional source of vitamin C
Source of vitamin C
Lack of vitamin C
Lack of vitamin C
Lack of C vitamins
Vitamin C deficiency
Vitamin C deficiency
Increased need for vitamin C
Increased need for vitamin C
Increased need for vitamin C during breastfeeding
Increased body need for ascorbic acid during growth
Increased body need for vitamin C
Scorbut
Scurvy
  • With iodine
  • With lecithin
  • All mothers know about the usefulness of vitamin C, so its intake in children's organism attention is paid from the very birth, making up a rational menu for the baby. If it is not possible to provide the child with a sufficient amount of ascorbic acid with food, they resort to vitamin supplements. From how many years it is permissible to give pharmaceutical preparations with vitamin C to prevent its lack and for what diseases they are needed in childhood?

    Release form

    Ascorbic acid is produced by:

    • In tablets.These round tablets can be white, pink, orange or other color depending on the composition. They include 25 mg or 100 mg of ascorbic acid, but they also manufacture a preparation with 50 mg, 75 mg, 300 mg or 500 mg of such a vitamin compound. One pack contains 10, 50 or 100 tablets.
    • In a dragee. These are often small spherical vitamins. yellow color... Each tablet contains 50 mg of vitamin. One package contains 50, 100, 150 or 200 pills.
    • In ampoules. This form of ascorbic acid is intended to be administered into a vein or intramuscular injection... This is a 5% or 10% clear solution, poured into 1 or 2 ml ampoules. One package contains 5 or 10 ampoules.
    • Powdered. A solution is prepared from it, which must be taken orally. The powder is a colorless or white, odorless crystal. It is packaged in bags of 1 or 2.5 g. One pack contains from 5 to 100 such bags.

    Composition

    The powder form contains only ascorbic acid. In tablets and dragees, in addition to the main substance, there may be sucrose, wax, calcium stearate, dye, dextrose, starch, lactose, talc, crospovidone and other auxiliary ingredients. In addition to vitamin C, the injectable form may contain water, sodium sulfite and bicarbonate, cysteine, disodium edetate.

    Operating principle

    Once in the body, ascorbic acid has the following effect:

    • Normalizes the permeability of small vessels.
    • Protects cells and tissues from toxic substances (antioxidant effect).
    • Strengthens the defenses, preventing viral infections and colds by activating the formation of antibodies and interferon.
    • Helps metabolize glucose.
    • It has a positive effect on liver function.
    • Regulates blood clotting.
    • Accelerates skin healing in case of damage.
    • Participates in the formation of collagen.
    • Helps absorb iron and folic acid.
    • Activates digestive enzymes, improves bile secretion, pancreatic and thyroid gland.
    • Reduces the manifestations of allergies and inflammation by inhibiting the formation of mediators involved in these pathological processes.

    How vitamin C affects the body and what are the indications and contraindications for the use of ascorbic acid - see in a short video:

    Indications

    • If his diet is unbalanced and there is a risk of hypovitaminosis.
    • During the active growth of the child's body.
    • To prevent ARVI. This reason is relevant in autumn, winter cold and early spring.
    • If the child has increased emotional or physical stress.
    • If the baby is recovering from injury or surgery.

    For therapeutic purposes, vitamin C preparations are prescribed:

    • With diagnosed hypovitaminosis C.
    • With hemorrhagic diathesis.
    • With nose and other bleeding.
    • When infectious diseases or intoxications.
    • With excessive use of iron supplements for a long time.
    • With acute radiation sickness.
    • With anemia.
    • With hepatic pathologies.
    • With colitis, peptic ulcer, enteritis or achilia.
    • With cholecystitis.
    • With sluggish healing of burns, ulcers or wounds on the skin.
    • With bone fractures.
    • With dystrophy.
    • With helminthiasis.
    • For chronic dermatoses and some other skin diseases.

    At what age can you give?

    Give drugs with ascorbic acid one year old child it is impossible. Tablets, which contain 25 mg of ascorbic acid, are prescribed from the age of 3. Dragee with a vitamin content in a dose of 50 mg is prescribed for children over 5 years old.

    Such age restrictions are associated with difficulties in swallowing the drug in early age, as well as the risk of inhaling pills. If necessary, your doctor may prescribe vitamin C earlier, but you should not do this yourself. Even when the child is already 3 years old or more, it is worth consulting a pediatrician about the use of such a vitamin.

    Contraindications

    Instructions for use prohibit ascorbic acid in such cases:

    • If the patient has an intolerance to such a vitamin.
    • If there is a tendency to thrombosis or thrombophlebitis is detected.
    • If the child has diabetes (for forms with sugar).
    • If the blood test showed too high level hemoglobin.
    • If a small patient is diagnosed with severe renal pathology.

    Side effects

    Sometimes the child's body reacts to the intake of ascorbic acid with allergies. These are often skin changes that manifest themselves with redness, itching, and rashes.

    Vitamin C treatment can also lead to:

    • Thrombocytosis, erythropenia, leukocytosis due to neutrophils.
    • Weakness and dizziness (if injected too quickly into a vein).
    • Diarrhea (with high dosage)
    • Nausea or vomiting.
    • Damage to tooth enamel (with prolonged absorption in the mouth).
    • Fluid and sodium retention.
    • Formation of oxalate stones in the urinary tract (with prolonged use of high doses).
    • Disruption of metabolic processes.
    • Kidney damage.
    • Soreness at the injection site (if injected intramuscularly).

    Instructions for use and dosage

    • Ascorbic acid tablets with glucose or pills are offered to the child after meal.
    • Prophylactic dose for babies 3-10 years old, it is represented by 1 tablet containing 25 mg of the vitamin, and at the age of over ten years, this daily dosage is increased to two tablets (50 mg per day).
    • Therapeutic doseis 2 tablets of 25 mg of ascorbic acid per day under the age of 10 years (daily dose of 50 mg) and three to four tablets of the drug over the age of 10 years (daily dose of 75-100 mg).
    • Ascorbic acid prophylactically is recommended to be taken from two weeks to two months... The duration of the treatment course is determined by the doctor.
    • If dosage active substance the tablet contains 100 mg, then such ascorbic acid is given in a dose of 1/2 tablet per day to children over 6 years old.
    • Dragee is given for prophylaxis to children over five years old, 1 piece per day, and for treatment - 1-2 pills up to 3 times a day.
    • Only a doctor should prescribe Ascorbic acid to children in injections.... The daily dosage is 1-2 ml of the drug, but a more accurate dose, route of administration and duration of therapy should be determined by a specialist, taking into account the disease in a particular child.

    Overdose

    Since ascorbic acid is a water-soluble compound, hypervitaminosis does not develop with an overestimated dosage of this vitamin. However, unnecessarily high doses of such a substance can damage the lining of the stomach and intestines, which leads to abdominal pain, diarrhea, bloating, vomiting and other negative symptoms.

    Also, poisoning with a very large amount of vitamin C is manifested by weakness, sweating, hot flashes, insomnia, and headaches. In addition, an excess of this substance will reduce capillary permeability, which will impair tissue nutrition, increase blood pressure and can lead to hypercoagulation.

    To prevent ascorbic acid from causing discomfort, you should know about the maximum recommended dosages of such a vitamin:

    • For children under 3 years old, this is 400 mg per day.
    • For a child aged 4 to 8 years, the maximum dose per day is called 600 mg.
    • For children 9 to 13 years old, do not exceed 1200 mg per day.
    • Over the age of 14, the permissible maximum of ascorbic acid per day is 1800 mg of this vitamin.

    Watch an informative video, which tells what can happen if you allow an excess of vitamin C in the body:

    Interaction with other drugs

    • The use of ascorbic acid will increase the blood levels of penicillin and tetracycline antibiotics, as well as salicylates.
    • With the combined intake of vitamin C and acetylsalicylic acid, the absorption of ascorbic acid worsens. The same effect is observed when drinking ascorbic acid with an alkaline liquid or fresh juice.
    • Simultaneous use with anticoagulants will reduce their therapeutic effect.
    • Taking vitamin C together with iron supplements promotes better absorption of Fe in the intestine. If ascorbic acid and deferoxamine are prescribed, iron toxicity will increase, which will negatively affect the heart and its work.
    • To mix injection form vitamin C in the same syringe with any medications is not recommended, since many drugs enter into chemical reactions with ascorbic acid.
    • With simultaneous treatment with barbiturates, the excretion of ascorbic acid in the urine increases.

    Terms of sale

    You do not need a prescription to buy Ascorbic Acid in pharmacies. The price of 10 ampoules of 2 ml with a 5% solution of ascorbic acid is about 40 rubles. A jar of 50 mg vitamin C pills costs 20-25 rubles, and a package of 25 mg tablets, which contain glucose, costs about 10-20 rubles.

    Storage conditions and shelf life

    The place where you need to place Ascorbic acid for better preservation should not be very humid, hot or light. In addition, you need to keep the drug where small children cannot get to it.

    The shelf life of tablets with ascorbic acid is 1-3 years from different manufacturers, 5% solution for injections is stored for up to a year, 10% solution and pills - 18 months from the date of release.

    Active substance

    Pharmacological group

    Nosological classification (ICD-10)

    Composition and form of release

    1 ampoule with lyophilized powder for preparation of an injection solution contains 0.05 g of ascorbic acid, complete with water for injection, in 2 ml ampoules; the package contains 5 sets.

    pharmachologic effect

    Participates in the regulation of carbohydrate metabolism of redox processes, blood coagulability, capillary permeability, tissue regeneration, synthesis of steroid hormones, collagen, procollagen.

    Indications of the drug Ascorbic acid with glucose

    Avitaminosis and hypovitaminosis C; hemorrhagic diathesis, bleeding (nasal, pulmonary, hepatic, uterine, caused by radiation sickness); overdose of anticoagulants; infectious diseases and intoxication; Addison's disease, nephropathy of pregnancy; sluggish healing wounds and bone fractures; dystrophy; mental and physical stress.

    Side effects

    Suppression of the function of the insular apparatus of the pancreas (with prolonged use).

    Method of administration and dosage

    In / m, in / in, before administration, the lyophilized powder is dissolved in 1-2 ml of sterile water for injection, for adults - 1-3 ml of a 5% solution (2-6 ml of a 2.5% solution) per day; children - 1-2 ml of a 5% solution (2-4 ml of a 2.5% solution) per day.

    Precautionary measures

    It is prescribed with caution in case of increased blood clotting, thrombophlebitis, tendency to thrombosis, diabetes mellitus. It is necessary to monitor renal function and blood pressure, especially when large doses are prescribed.

    Storage conditions of the drug Ascorbic acid with glucose

    Keep out of the reach of children.

    Shelf life of the drug Ascorbic acid with glucose

    lyophilisate for the preparation of a solution for intravenous and intramuscular administration 0.05 g - 2 years.

    tablets 100 mg + 877 mg 100 mg + 877 - 1 year.

    dragee 50 mg - 1.5 years.

    Do not use after the expiration date printed on the package.

    Prices in pharmacies in Moscow

    The information on the prices of drugs provided does not constitute an offer to sell or buy a product.

    The information is intended solely for comparing prices in inpatient pharmacies operating in accordance with Article 55 of the Federal Law "On the Circulation of Medicines" dated 12.04.2010 N 61-FZ.

    tablets 100 mg + 877 mg 100 mg + 877, 10 pcs.

    tablets 100 mg + 877 mg 100 mg + 877, 40 pcs.

    Dropper glucose with ascorbic acid dosage

    in pharmacies of Belarus

    (information for specialists)

    on the medical use of the medicinal product

    Approved by the Ministry of Health of the Republic of Belarus

    Order No. 393 dated 04/14/2015

    Tradename: Glucose.

    International non-proprietary name:Carbohydrates.

    Release form: solution for infusion 50 mg / ml or 100 mg / ml.

    Description: transparent colorless or slightly yellowish solution.

    Composition for one bottle:

    solution 50 mg / ml:

    active substance: anhydrous glucose - 20.0 g;

    excipient: water for injections.

    solution 100 mg / ml:

    active substance: anhydrous glucose - 40.0 g;

    excipients: hydrochloric acid 0.1 M solution, sodium chloride, water for injection.

    Pharmacotherapeutic group: Solutions for intravenous administration. Solutions for parenteral nutrition.

    Plasma-substituting, rehydrating, metabolic and detoxifying agent. The mechanism of action is due to the substrate inclusion of glucose in the processes of energy (glycolysis) and plastic (transamination, lipogenesis, nucleotide synthesis) metabolism.

    It participates in various metabolic processes in the body, enhances the redox processes in the body, improves the antitoxic function of the liver. Glucose, entering the tissues, is phosphorylated, turning into glucose-6-phosphate, which is actively involved in many links of the body's metabolism. When glucose is metabolized in tissues, a significant amount of energy is released, which is necessary for the vital activity of the body.

    100 mg / ml glucose solution is hypertonic in relation to blood plasma, with increased osmotic activity. When intravenous administration increases the output of tissue fluid into the vascular bed, increases diuresis, increases the excretion of toxic substances in the urine, improves the antitoxic function of the liver.

    When diluted to an isotonic state (solution 50 mg / ml), it replenishes the volume of lost fluid, maintains the volume of circulating plasma.

    The theoretical osmolality of a 50 mg / ml glucose solution is 287 mOsm / kg.

    Theoretical osmolality of glucose solution 100 mg / ml - 602 mOsm / kg

    When administered intravenously, the glucose solution quickly leaves the vascular bed.

    Transport into the cell is regulated by insulin. In the body, we undergo biotransformation along the hexose phosphate pathway - the main pathway of energy metabolism with the formation of high-energy compounds (ATP) and the pentose phosphate pathway - the main

    the way of plastic metabolism with the formation of nucleotides, amino acids, glycerol.

    Glucose molecules are utilized in the process of energy supply to the body. Glucose, entering the tissues, is phosphorylated, turning into glucose-6-phosphate, which is subsequently included in the metabolism (the end products of metabolism are carbon dioxide and water). Easily penetrates through histohematogenous barriers into all organs and tissues.

    It is absorbed completely by the body, it is not excreted by the kidneys (the appearance in the urine is a pathological sign).

    Indications for use

    A solution of glucose 50 mg / ml is used to replenish the volume of fluid during cellular and general dehydration, with extracellular hyperhydration.

    Glucose solution 100 mg / ml is used for hypoglycemia and liver diseases (hepatitis, cirrhosis, hepatic coma), for osmotherapy in case of insufficient diuresis, collapse and shock, in severe infectious diseases, decompensation of cardiac activity, various intoxications (drug poisoning, cyanide, carbon monoxide, etc.), with hemorrhagic diathesis, for parenteral nutrition.

    Glucose solutions can be used both independently and according to indications in combination with other medicinal substances (sodium chloride, potassium chloride, NaEDTA, etc.), and also used for dilution of medicines.

    Method of administration and dosage regimen

    Before the introduction, the doctor must conduct a visual examination of the bottle with the drug. The solution must be clear, free of suspended particles or sediment. A medicinal product is considered suitable for use if there is a label and the package is sealed.

    The concentration and volume of glucose solution administered for intravenous infusion is determined by a number of factors, including age, body weight and clinical condition the patient. It is recommended that you periodically measure your blood glucose level.

    Isotonic solution 50 mg / ml injected intravenously with a recommended injection rate of 70 drops / minute (3 ml / kg of body weight per hour).

    Hypertonic solution 100 mg / ml injected intravenously at a recommended rate of 60 drops / minute (2.5 ml / kg of body weight per hour).

    It is allowed to introduce solutions of 50 mg / ml and 100 mg / ml glucose intravenously in a stream - 10-50 ml.

    In adults with a normal metabolism, the daily dose of injected glucose should not exceed 1.5-6 g / kg of body weight per day (with a decrease in metabolic intensity, the daily dose is reduced), while the daily volume of injected fluid is 30-40 ml / kg.

    For children for parenteral nutrition, along with fats and amino acids, 6 g / kg / day is administered on the first day, and then up to 15 g / kg / day. When calculating the dose of glucose with the introduction of solutions of 50 mg / ml and 100 mg / ml of dextrose, you need to take into account the permissible volume of injected fluid: for children weighing 2-10 kg - 100-165 ml / kg / day, children weighing 10-40 kg - 45-100 ml / kg / day.

    When using a glucose solution as a solvent, the recommended dose is 50-250 ml per dose of the drug to be dissolved, the characteristics of which also determine the rate of administration.

    Adverse reactions at the injection site: pain at the injection site, irritation of the veins, phlebitis, venous thrombosis.

    Endocrine system and metkbolism disorders: hyperglycemia, hypokalemia, hypophosphatemia, hypomagnesemia, acidosis.

    External violations digestive tract: polydipsia, nausea.

    General reactions of the body: hypervolemia, allergic reactions (increased body temperature, skin rashes, hypervolemia).

    In case of occurrence adverse reactions the introduction of the solution should be stopped, the patient's condition should be assessed and assistance should be provided. The solution that remains should be kept for later analysis.

    Hypersensitivity, hyperglycemia, hyperlactacidemia, hyperhydration, postoperative glucose utilization disorders; circulatory disorders threatening cerebral and pulmonary edema; cerebral edema, pulmonary edema, acute left ventricular failure.

    Caution: decompensated chronic heart failure, chronic renal failure (oligo-, anuria), hyponatremia, diabetes mellitus.

    Overdose can cause hyperglycemia, hyperhydration, hypervolemia, hypokalemia.

    Therapy depends on the type and severity of disorders: discontinuation of infusion, administration of insulin (1U of insulin for 4-5g of glucose), diuretics, electrolytes.

    For a more complete assimilation of glucose, administered in large doses, insulin is prescribed simultaneously with it at the rate of 1 U of insulin per 4-5 g of glucose. For diabetic patients, glucose is administered under the control of its content in blood and urine. During treatment, it is necessary to monitor the ionogram.

    The use of glucose in patients with acute ischemic stroke may slow down the healing process.

    To avoid hyperglycemia, the level of possible glucose oxidation must not be exceeded.

    The glucose solution cannot be administered quickly or long time... If chills occur during the administration, the administration should be stopped immediately. To prevent thrombophlebitis, it should be administered slowly through large veins.

    When renal failure, decompensated heart failure, hyponatremia required special care when prescribing glucose, control of indicators of central hemodynamics.

    Application during pregnancy and lactation. Glucose solution for infusion should be administered with caution to women during pregnancy and lactation.

    Influence on the ability to drive vehicles and other potentially dangerous mechanisms. Does not affect.

    Interacting with others medicines

    When combined with other drugs, it is necessary to clinically monitor their possible incompatibility (possible invisible pharmaceutical or pharmacodynamic incompatibility).

    The glucose solution should not be mixed with alkaloids (their decomposition occurs), with general anesthetics (decreased activity), with hypnotics (their activity decreases).

    Glucose weakens the activity of analgesics, adrenomimetics, inactivates streptomycin, and reduces the effectiveness of nystatin.

    Due to the fact that glucose is a fairly strong oxidizing agent, it should not be injected in the same syringe with hexamethylenetetramine.

    Under the influence of thiazide diuretics and furosemide, glucose tolerance decreases.

    Glucose solution reduces the toxic effect of pyrazinamide on the liver. The introduction of a large volume of glucose solution promotes the development of hypokalemia, which increases the toxicity of simultaneously prescribed digitalis drugs.

    Glucose is incompatible in solutions with aminophylline, soluble barbiturates, erythromycin, hydrocortisone, warfarin, kanamycin, soluble sulfonamides, cyanocobalamin.

    Glucose solution should not be administered in the same infusion set with blood due to the risk of nonspecific agglutination.

    Since the glucose solution for intravenous infusion is acidic (pH<7), может возникнуть несовместимость при одновременном введении с другими лекарственными средствами.

    Store at a temperature not exceeding 25 ºС.

    Keep out of the reach of children.

    Do not use after the expiration date printed on the package.

    400 ml in glass bottles for blood, transfusion and infusion preparations. Each bottle, along with instructions for use, is placed in a pack.

    For delivery to hospitals: 24 bottles, together with the appropriate number of instructions for use, in corrugated cardboard boxes.

    Dispensing from pharmacies

    All rights belong to RUE Belmedpreparaty9raquo ;.

    When using materials from the portal in whole or in part for other purposes, a link to the source is required!

    Ascorbic acid, or ascorbic acid, is a well-known vitamin C. It is often taken during illness to activate the body's defenses. it biologically active substance takes part in all metabolic processes... The daily requirement for ascorbic acid is 100 mg.

    Sources of Vitamin C

    An increased amount of ascorbic acid is found in citrus fruits, various varieties of cabbage, rose hips, currants, apples, bell peppers, strawberries, tomatoes and persimmons.

    Pharmaceutical fortified preparations available in the form of tablets, lozenges and ampoules for injection... It is an overdose of such drugs that causes side effects on the body.

    Why vitamin C is useful

    Ascorbic acid is vital, its benefit is to activate the immune system. She also takes an active part in the process of hematopoiesis, improves the functionality of the nervous and endocrine systems.

    Vitamin C is considered a powerful antioxidant that removes free radicals from the body... Ascorbic acid is essential for the growth and development of connective tissue and collagen fibers. A sufficient level of this substance is an effective prevention of inflammatory and infectious diseases.

    Energy production of the tissues of the human body also largely depends on ascorbic acid, which is involved in the synthesis of carnitine.

    Indications for taking vitamin C tablets

    In addition to the prevention of hypo- and avitaminosis, doctors recommend taking ascorbic acid in such cases:

    • the period of growth and puberty;
    • pregnancy and breastfeeding;
    • during heavy physical exertion;
    • a state of chronic overwork;
    • the rehabilitation period after a serious illness or injury;
    • in winter and spring time to prevent the development of viral diseases;
    • with acute and chronic blood loss;
    • intoxication and dystrophy of the body.

    How to take vitamin C correctly

    In order for ascorbic acid not to cause harm, it is necessary to remember about contraindications, symptoms of overdose and the dosage of vitamin preparations. Each pharmacy contains an admission rate for children and adults.

    Experts pay attention that during pregnancy ascorbic acid easily overcomes the placental barrier. In this regard, you should not consume increased amounts of vitamin C. Also, special attention should be paid to the dosage of the drug for women during breastfeeding. During this time, ascorbic acid can often cause allergic reactions in the child.

    The intake of a pharmaceutical agent for patients with chronic diseases of the urinary and cardiovascular system is agreed with the attending physician, who, if necessary, will adjust the duration and dosage of the course of therapy.

    Contraindications

    An absolute contraindication to taking vitamin C is that the patient has an allergic reaction to ascorbic acid. In such cases the patient has redness and itching of the skin... In more severe cases, the person suffers from edema of the mucous membrane of the upper respiratory tract.

    According to the instructions for the drug, special care should be taken by people with diabetes mellitus, anemic conditions and urolithiasis.

    The pharmaceutical agent "ascorbic acid", the benefit or harm of which directly depends on the dosage, recommended to be taken orally after meals... For children, the dosage of the drug is usually two times less than for adult patients.

    Excessive doses of vitamin C

    For the first time, the American scientist L. Pauling, who studied the effect of vitamins on the course of oncological diseases, mentioned the therapeutic effect of ultra-high doses of ascorbic acid. In such cases, ascorbic acid significantly improves the general well-being of a cancer patient.

    If the drug is taken prophylactically, then many patients develop complications from the gastrointestinal tract. At the same time, ascorbic acid is harmful, it causes gastritis and ulcerative lesions of the gastrointestinal mucosa.

    In 2000, at the World Cardiology Congress, it was reported that high doses of vitamin C provoke atherosclerosis... Excessive use of vitamin preparations by young patients can be accompanied by allergic reactions and nephrological disorders.

    The use of a vitamin product in combination with glucose

    Ascorbic acid with glucose is sold in pharmacy nets. The benefit or harm of such a pharmaceutical agent depends on the patient's compliance with the dosage. The features of this tool are that:

    • artificially synthesized vitamin C is formed from glucose;
    • using these two ingredients together improves liver function;
    • glucose provides a quick energy boost to the body.

    Indications for the use of vitamin C and glucose

    This remedy is used in the following cases:

    • The presence of symptoms of overwork, excessive irritability and chronic ailments.
    • Signs of increased blood vessel permeability.
    • Chronic periodontitis (inflammation of the mucous membrane of the periodontal tissues), bleeding gums.
    • People who are at an increased risk of developing infectious diseases. In this case, the drug is recommended for children who often suffer from bacterial and viral diseases.
    • Vitamin complex with glucose is beneficial for food poisoning as part of a complex detoxification therapy.
    • The remedy is recommended for chronic pain in the extremities, disorders of the development of bone tissue and loosening of the dentition.
    • Formation of hemorrhagic diathesis.

    Consequences of an overdose of vitamin C and glucose

    Exceeding the norms for the use of ascorbic acid and glucose is accompanied by the following complications:

    • a sharp narrowing of the lumen of blood vessels due to thrombophlebitis and thrombosis;
    • acute disruption of the pancreas, which is manifested by the detection of glucose in the urine and a disorder of glycogen synthesis;
    • dysfunction of the gastrointestinal tract in the form of frequent nausea, heartburn and pain attacks;
    • in some cases, the patient has urticaria with increased sensitivity of the body to ascorbic acid;
    • long-term intake of vitamin C and glucose provokes the formation of kidney stones;
    • progression of arterial hypertension.

    Medical care for patients with ascorbic poisoning

    The first manifestation of an overdose is a violation of the digestive process. The basic principles of treatment are as follows:

    • gastric lavage and the use of sorbents are effective in the first hours of poisoning due to the fact that ascorbic acid is rapidly absorbed through the gastric mucosa;
    • immediate hospitalization of the patient, which is indicated even with allergic symptoms. The patient must be under constant medical supervision;
    • symptomatic treatment of complications. So, for example, the presence of blood clots requires specific thrombolytic treatment for resorption of blood clots;
    • a decrease in the aggressive effect of an increased concentration of ascorbic acid is achieved by introducing vitamins of groups A and E. Such treatment requires constant medical monitoring.

    Ascorbic acid is beneficial for the body in most cases. The side effect of the drug is associated exclusively with an overdose of vitamin C.

    For good health and proper functioning of all organs and systems, a person needs to receive a certain amount of nutrients every day. One of the most famous vitamin remedies is ascorbic acid with glucose. Ascorbic acid has many functions and is therefore irreplaceable. In addition, it is not produced on its own and enters the body only from the outside. The drug is produced in several forms.

    How does the drug work?

    Ascorbic acid, combined with glucose, is a powerful naturally occurring antioxidant that is involved in many biochemical reactions. A water-soluble vitamin is essential for metabolic processes (regulates carbohydrate metabolism) and collagen synthesis, participates in the formation of steroid hormones and tissue regeneration. The drug has a positive effect on the content of harmful cholesterol in the blood, increases the accumulation of liver glycogen. The latter property has a beneficial effect on the detoxification function of the filter organ.

    Ascorbic acid with glucose has anti-inflammatory and antihistamine properties, regulates capillary permeability. It has been established that the remedy can be effective in radiation sickness, reducing hemorrhagic symptoms and stimulating hematopoiesis. The compound improves the absorption of iron, promotes the healing of various wounds (including burns).

    In the small intestine, the drug is rapidly absorbed. After 30-40 minutes, a significant increase in the concentration of the substance in the blood serum is observed. The excess is excreted from the body in the form of ascorbic acid metabolites along with urine. An overdose of the drug is almost impossible.

    The benefits of ascorbic acid

    Ascorbic acid in the human body is not synthesized and comes mainly from food. The daily norm of the substance is 100 mg. Ascorbic acid with glucose is the strongest stimulant of the immune system.

    How to identify ascorbic acid deficiency?

    Experts say that ascorbic acid should be ingested on a regular basis. With a lack of connection, a weakening of protective functions is observed, and the overall tone decreases. Deficiency can be determined by the following symptoms:

    • increased frequency of colds;
    • decreased appetite;
    • dryness of the epidermis;
    • anemia (decreased hemoglobin);
    • bleeding gums;
    • apathy, irritability;
    • memory impairment;
    • lag in physical and mental development (in young children).

    Glucose with ascorbic acid: indications for appointment

    The drug has a wide range of applications and is prescribed for the treatment of ailments of various etiologies. Most often, ascorbic acid is recommended to be taken if necessary to mobilize the protective functions of the body. Daily intake of the vitamin compound significantly reduces the risk of upper respiratory tract infection. For the normal production of hormones by the adrenal glands and the thyroid gland, ascorbic acid with glucose is also indicated.

    • treatment and prevention of avitaminosis, hypovitaminosis;
    • bleeding of various etiologies;
    • liver pathology (hepatitis, cholecystitis);
    • addison's disease;
    • parenteral administration of food;
    • sluggish wound healing process;
    • intoxication of the body;
    • bone fractures;
    • hypothermia of the body;
    • peptic ulcer, gastrectomy;
    • period of pregnancy and lactation;
    • unbalanced diet;
    • skin diseases;
    • atherosclerosis;
    • lupus;
    • scleroderma;
    • dystrophy;
    • recovery period after a viral or infectious disease;
    • nephropathy during pregnancy.

    When is intravenous administration of the drug necessary?

    The vitamin preparation is available in several forms: tablets, powder and solution (intended for injection). In case of uncomplicated pathological conditions, patients are most often recommended to take the drug in the form of tablets orally. If the disease poses a serious threat to life, intravenous glucose with ascorbic acid is prescribed. Injection therapy allows you to quickly eliminate the acid deficiency in the body.

    The dosage of the medicine is selected by a specialist depending on the patient's condition. For medicinal purposes, 1-3 ml of liquid diluted with saline is administered intravenously or intramuscularly. 1 ml of the drug contains 50 mg of ascorbic acid. The maximum daily dose should not exceed 4 ml.

    Ascorbic acid for children

    One of the most important elements for a growing body is ascorbic acid. This vitamin preparation has a positive effect on the functioning of the nervous system, helps the gland to be properly absorbed, and cleanses the body of harmful compounds and substances.

    Children are prone to viral and colds at any age. This is due to the insufficient development of the immune system and the unwillingness to resist pathogenic microorganisms. Ascorbic acid with glucose will help to improve the state of the defense system. The instruction allows you to prescribe the drug in tablets to babies from the age of three. As a preventive measure, it is recommended to give one tablet (50 mg of ascorbic acid) to chew a day. If correction of the deficiency state is needed, the dose should be increased to 2-3 tablets per day.

    In pediatric practice, intravenous glucose with ascorbic acid can also be prescribed. Indications for use are usually associated with frequent colds and infectious pathologies, dystrophy, anemia and anemia. The therapeutic dose is determined by the doctor. The duration of treatment depends on the severity of the pathological condition and is usually 10-14 days.

    Contraindications

    It should be remembered that ascorbic acid is not just sweet and healthy candies, but, first of all, a drug. Therefore, before using it, you should familiarize yourself with the presence of certain conditions in which it is prohibited to take the drug.

    Patients with a tendency to allergic reactions and glucose intolerance are not prescribed ascorbic acid with glucose. The instructions for use refer this to the main contraindications. You should not take medicine for diabetes mellitus and high blood clotting rates. It is forbidden to prescribe ascorbic acid for thrombophlebitis, thrombosis, kidney stones. Ascorbic acid is taken with caution in pathologies of the gastrointestinal tract. You must first consult a specialist regarding treatment with ascorbic acid with glucose.

    Ascorbic acid with glucose during pregnancy

    During gestation, the body of the expectant mother needs a regular supply of useful minerals, compounds and substances for the normal course of pregnancy and the intrauterine development of the baby. Vitamin deficiency can negatively affect his health. For a woman, vitamin C is equally important. After all, it promotes the production of collagen, which is the prevention of the formation of striae (stretch marks) and varicose veins. Also, ascorbic acid improves the condition of muscle tissue, reduces the likelihood of bleeding.

    The main supply of ascorbic acid in the body of the expectant mother is intended for the proper development of the fetus, and therefore most often the lack of vitamin affects the woman's health. During pregnancy, it is recommended to take ascorbic acid daily. Safe dosage for expectant mother and baby is 2 g per day. It should be borne in mind that the vitamin compound also enters the body with some food.

    Side effects

    Ascorbic acid with glucose is usually well tolerated by the body and does not provoke side effects. However, if the instructions for use or the recommended dosage are not followed, negative reactions develop. On the part of the immune system, allergies may appear: skin rash, itching, redness.

    The central nervous system also reacts to an excess of the vitamin in the body. In case of an overdose, symptoms such as headache, insomnia, and increased irritability may appear. Ascorbic acid with glucose in overestimated doses (with prolonged use) can cause metabolic disorders, increased blood pressure, promote the formation of blood clots, increase blood clotting and reduce capillary permeability.

    Patient reviews

    Ascorbic acid with added glucose is considered an inexpensive and quite effective vitamin preparation that has earned a huge number of positive recommendations. Many patients take the drug in tablet form to raise immunity and prevent vitamin deficiencies in the autumn and spring. Ascorbic acid in the form of large round white tablets is often given to young children.

    Ascorbic acid in the form of yellow beads is also used in the preparation of home cosmetics. Masks based on this product, according to consumers, help improve the condition of the skin on the face, tighten pores, and remove oily sheen.

    Bright yellow peas of vitamin "C" in elegant plastic jars, large white tablets in a shiny cellophane wrapper - this is the famous Ascorbic acid with glucose, which has been loved by all children for a long time. Its benefits and harms are determined individually for each organism: it depends on the number of balls eaten (cakes, lozenges), as well as certain contraindications.

    Who can and should constantly consume synthesized vitamin C, and for which of the people the only way to saturate the body with ascorbic acid with glucose is natural: berries, fruits, vegetables?

    The healing power of vitamin "C"

    Ascorbic acid and glucose, contained in fresh roots, herbs, fruits of plants, are certainly more useful for humans than artificially created preparations of vitamin "C". However, during storage of products, natural biological active substances are quickly destroyed.

    The reserves of energy and vitality of vegetation are sufficient only until the beginning of winter. Further, a person gradually develops a deficiency of ascorbic acid, which threatens with unpleasant consequences: metabolic disorders, decreased immunity.

    What invaluable benefits does our body receive from consuming ascorbic acid from the pharmacy?

    • Protection against pathogens, viruses, bacteria, fungi and other pathogenic microorganisms.
    • Improving the function of hematopoiesis and blood circulation by accelerating the absorption of iron.
    • Cleansing the liver, lungs, and other organs from toxins due to their rapid neutralization and elimination.
    • Stimulation of the brain.
    • Acceleration of the metabolic process.
    • Active regeneration of damaged cells of muscle, bone, epithelial tissues of the body.
    • Maximum saturation of the body with oxygen due to the cleansing of blood vessels.
    • Supplying the nervous system with carbohydrate energy.
    • Assistance in the breakdown of fatty deposits in the waist, abdomen, hips.
    • For women who are nursing (and carrying) a child, it guarantees the formation of strong immunity of the baby to colds.

    Ascorbic acid is a powerful antioxidant, therefore, its field of application for the treatment and strengthening of the body is very wide.

    Medical indications for the mandatory use of Vitamin C preparations

    In cold periods of the year, ascorbic acid with glucose is especially necessary for children, people weakened by chronic diseases, as well as for pregnant women. In addition, the following life situations are indications for daily use:

    • Feeling tired, weak, physically impotent.
    • Decreased libido as well as erection ability in men.
    • Nervous nervousness, irritability, depression.
    • Puffiness of the face, swelling of the limbs, bloating.
    • Bleeding gums, periodontal disease, stomatitis.
    • Respiratory tract infections.
    • Allergenic hyperreactivity of the body.
    • Heart, liver failure.
    • Multiple pregnancy in women.
    • With chemical, biological poisoning.
    • People who smoke, as well as people who abuse alcohol and drugs, have a constant deficiency of vitamin "C".

    For women who dream of unearthly beauty, ascorbic acid with glucose is both good and bad: the more fresh plants they consume with food, the more velvety, smooth, and tender the skin becomes. Wrinkles disappear, look and lush hairstyle become radiant.

    But excessive consumption of synthesized Vitamin "C" (hypervitaminosis) leads to the opposite effect: coarsening of the cells of the skin of the face, neck, dry mucous eyes, brittle hair and nails.

    How much vitamin C can you eat without fear of overdose

    The main rule of use: after meals.

    In pharmacies, Ascorbic acid with glucose can be found in the following release forms:

    1. Large chewable tablets. In 1 piece 100 mg of vitamin "C".
    2. Dragee. 1 pea - 50 mg.
    3. Absorbable small tablets - 100 mg
    4. Effervescent tablets and powders - loading doses up to 1000 mg per unit (for adults only).

    The decision on the individual rate of use of the fortified drug is made exclusively by the doctor, only general methods of use are printed in the instructions:

    1. For children over three years old, prophylactic norms per day are no more than 25 mg, therapeutic norms are from 50 to 100 mg.
    2. Adults: for prophylaxis - from 50 to 125 mg, for treatment - from 100 to 250 mg.
    3. For pregnant women and nursing mothers - from 200 to 300 mg.
    4. For athletes with a powerful physical load - up to 350 mg.
    5. People who smoke need to increase the intake of vitamin C with glucose by a third or even half of the recommended quantitative indicators.

    Contraindications for use are detailed in each instruction for the drug, however, only the attending doctor can provide accurate information about the possibility of use for a particular disease.

    General contraindications

    Ascorbic acid with glucose can cause harm not only by exceeding the norm, but also in some pathological conditions of the body. What serves as a prohibition:

    • Increased blood clotting.
    • Predisposition to thrombosis.
    • Diabetes.
    • Allergic intolerance to fructose, starch, talc, and other ingredients of the drug.
    • Renal failure
    • Gastritis against a background of high acidity, ulcerative erosion of the gastrointestinal tract.

    It is not recommended to take this drug at the same time as tablets containing high levels of iron, folic acid, caffeine, unpleasant side effects may occur due to incompatibility.

    If, when using ascorbic acid preparations, heartburn, nausea, a rash of urticaria occurs, you must immediately stop drinking pills (pills, powders).

    People's advice: sauerkraut will save you from vitamin C deficiency in winter. Unlike all vegetables and fruits, by spring it is gaining shock doses of natural ascorbic acid due to the process of lactic acid fermentation of beneficial bacteria. Other inexhaustible vitamin sources are garlic, onions, lemons, cranberries, lingonberries.

    If you have additional questions, we invite you to chat in the comments to the article.

    Best regards, Vladimir Manerov

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    Ascorbic acid, or ascorbic acid, is a well-known vitamin C. It is often taken during illness to activate the body's defenses. it biologically active substance takes part in all metabolic processes... The daily requirement for ascorbic acid is 100 mg.

    Sources of Vitamin C

    An increased amount of ascorbic acid is found in citrus fruits, various varieties of cabbage, rose hips, currants, apples, bell peppers, strawberries, tomatoes and persimmons.

    Pharmaceutical fortified preparations available in the form of tablets, lozenges and ampoules for injection... It is an overdose of such drugs that causes side effects on the body.

    Why vitamin C is useful

    Ascorbic acid is vital, its benefit is to activate the immune system. She also takes an active part in the process of hematopoiesis, improves the functionality of the nervous and endocrine systems.

    Vitamin C is considered a powerful antioxidant that removes free radicals from the body... Ascorbic acid is essential for the growth and development of connective tissue and collagen fibers. A sufficient level of this substance is an effective prevention of inflammatory and infectious diseases.

    Energy production of the tissues of the human body also largely depends on ascorbic acid, which is involved in the synthesis of carnitine.

    Indications for taking vitamin C tablets

    In addition to the prevention of hypo- and avitaminosis, doctors recommend taking ascorbic acid in such cases:

    • the period of growth and puberty;
    • pregnancy and breastfeeding;
    • during heavy physical exertion;
    • a state of chronic overwork;
    • the rehabilitation period after a serious illness or injury;
    • in winter and spring time to prevent the development of viral diseases;
    • with acute and chronic blood loss;
    • intoxication and dystrophy of the body.

    How to take vitamin C correctly

    In order for ascorbic acid not to cause harm, it is necessary to remember about contraindications, symptoms of overdose and the dosage of vitamin preparations. Each pharmacy contains an admission rate for children and adults.

    Experts pay attention that during pregnancy ascorbic acid easily overcomes the placental barrier. In this regard, you should not consume increased amounts of vitamin C. Also, special attention should be paid to the dosage of the drug for women during breastfeeding. During this time, ascorbic acid can often cause allergic reactions in the child.

    The intake of a pharmaceutical agent for patients with chronic diseases of the urinary and cardiovascular system is agreed with the attending physician, who, if necessary, will adjust the duration and dosage of the course of therapy.

    Contraindications

    An absolute contraindication to taking vitamin C is that the patient has an allergic reaction to ascorbic acid. In such cases the patient has redness and itching of the skin... In more severe cases, the person suffers from edema of the mucous membrane of the upper respiratory tract.

    According to the instructions for the drug, special care should be taken by people with diabetes mellitus, anemic conditions and urolithiasis.

    The pharmaceutical agent "ascorbic acid", the benefit or harm of which directly depends on the dosage, recommended to be taken orally after meals... For children, the dosage of the drug is usually two times less than for adult patients.

    Excessive doses of vitamin C

    For the first time, the American scientist L. Pauling, who studied the effect of vitamins on the course of oncological diseases, mentioned the therapeutic effect of ultra-high doses of ascorbic acid. In such cases, ascorbic acid significantly improves the general well-being of a cancer patient.

    If the drug is taken prophylactically, then many patients develop complications from the gastrointestinal tract. At the same time, ascorbic acid is harmful, it causes gastritis and ulcerative lesions of the gastrointestinal mucosa.

    In 2000, at the World Cardiology Congress, it was reported that high doses of vitamin C provoke atherosclerosis... Excessive use of vitamin preparations by young patients can be accompanied by allergic reactions and nephrological disorders.

    The use of a vitamin product in combination with glucose

    Ascorbic acid with glucose is sold in pharmacy nets. The benefit or harm of such a pharmaceutical agent depends on the patient's compliance with the dosage. The features of this tool are that:

    • artificially synthesized vitamin C is formed from glucose;
    • using these two ingredients together improves liver function;
    • glucose provides a quick energy boost to the body.

    Indications for the use of vitamin C and glucose

    This remedy is used in the following cases:

    • The presence of symptoms of overwork, excessive irritability and chronic ailments.
    • Signs of increased blood vessel permeability.
    • Chronic periodontitis (inflammation of the mucous membrane of the periodontal tissues), bleeding gums.
    • People who are at an increased risk of developing infectious diseases. In this case, the drug is recommended for children who often suffer from bacterial and viral diseases.
    • Vitamin complex with glucose is beneficial for food poisoning as part of a complex detoxification therapy.
    • The remedy is recommended for chronic pain in the extremities, disorders of the development of bone tissue and loosening of the dentition.
    • Formation of hemorrhagic diathesis.

    Consequences of an overdose of vitamin C and glucose

    Exceeding the norms for the use of ascorbic acid and glucose is accompanied by the following complications:

    • a sharp narrowing of the lumen of blood vessels due to thrombophlebitis and thrombosis;
    • acute disruption of the pancreas, which is manifested by the detection of glucose in the urine and a disorder of glycogen synthesis;
    • dysfunction of the gastrointestinal tract in the form of frequent nausea, heartburn and pain attacks;
    • in some cases, the patient has urticaria with increased sensitivity of the body to ascorbic acid;
    • long-term intake of vitamin C and glucose provokes the formation of kidney stones;
    • progression of arterial hypertension.

    Medical care for patients with ascorbic poisoning

    The first manifestation of an overdose is a violation of the digestive process. The basic principles of treatment are as follows:

    • gastric lavage and the use of sorbents are effective in the first hours of poisoning due to the fact that ascorbic acid is rapidly absorbed through the gastric mucosa;
    • immediate hospitalization of the patient, which is indicated even with allergic symptoms. The patient must be under constant medical supervision;
    • symptomatic treatment of complications. So, for example, the presence of blood clots requires specific thrombolytic treatment for resorption of blood clots;
    • a decrease in the aggressive effect of an increased concentration of ascorbic acid is achieved by introducing vitamins of groups A and E. Such treatment requires constant medical monitoring.

    Ascorbic acid is beneficial for the body in most cases. The side effect of the drug is associated exclusively with an overdose of vitamin C.

    The main »Benefits and harm» Ascorbic acid with glucose benefits and harms

    Ascorbic acid - benefit and harm

    As you know, ascorbic acid belongs to the category of organic compounds and is an irreplaceable substance in the human diet. It functions as a restorer of certain metabolic processes and is also an ideal antioxidant. However, not every person knows the benefits and harms of ascorbic acid in full.

    The main active ingredient in this preparation is vitamin C. Ascorbic acid is a white powder that dissolves almost instantly in water and other liquids. Ascorbic acid cannot harm human health if it is not consumed in large quantities. Overdose is the root of all problems. However, it is worth remembering that ascorbic acid may be contraindicated in people suffering from gastritis, ulcers and other diseases of the gastrointestinal tract, especially in the acute period.

    How is ascorbic acid useful?

    The benefits of this drug are judged by the signs of its lack in the body. Lack of vitamin C is expressed by the following symptoms:

    1. Weakening of immunity and general malaise.
    2. Pallor of the skin.
    3. Increased wound healing time.
    4. Bleeding gums.
    5. Anxiety, poor sleep and leg pain.

    As you know, ascorbic acid contains vitamin C, which prevents the development of the listed symptoms.

    1. This drug increases immunity, normalizes cholesterol levels, increases hemoglobin, improves blood composition, strengthens the walls of blood vessels.
    2. Ascorbic acid also has other beneficial properties: it promotes the production of the required amount of collagen, intended for the repair of cells, tissues and blood vessels.
    3. Vitamins ascorbic acid strengthen the cardiovascular system.
    4. Prevents the development of bronchitis.
    5. Reduces the risk of developing cancer. Ascorbic acid helps the immune system fight off dangerous microorganisms.
    6. Protects the body from toxic substances.

    Based on all these factors, it becomes clear whether ascorbic acid is useful or whether we use it in vain.

    What is ascorbic acid for in large quantities?

    The main cases of taking ascorbic acid in high dosages:

    1. People who have received severe poisoning with carbon monoxide, as well as other harmful substances. In case of poisoning, vitamin C quickly restores all the necessary processes in the body.
    2. This drug is taken in large quantities during the change of seasons, when the body is depleted and lacks all the necessary vitamins. Together with the drug, fruits and vegetables containing vitamin C should be added to the diet. All this will strengthen the immune system and help to painlessly transfer the off-season period.
    3. Pregnancy. During this period, women also experience a lack of ascorbic acid. However, they can only take it as directed by a doctor. He usually prescribes a third more drug to pregnant women than they used before pregnancy.
    4. Smoking. This addiction is equated to carbon monoxide poisoning, therefore it needs an increased dosage of vitamin "C". The fact is that ascorbic acid quickly restores the acidic environment in the body.

    Summing up, we can conclude that ascorbic acid is harmful only in the following cases:

    1. If you have problems with the gastrointestinal tract.
    2. In case of overdose.
    3. For people with kidney disease.

    Where to find ascorbic acid?

    WomanAdvice.ru\u206a\u003e

    Ascorbic acid - benefits and harms for the child's body

    Katsuzo Nishi argued that one of the main causes of tumors is a lack of vitamin C. Without this substance, the processes of regeneration of organs and tissues would be impossible. It was once considered the only cure for scurvy.

    But is the use of ascorbic acid so unique for modern peopleconsuming fruits and vegetables daily? Let's try to figure it out.

    Natural sources

    The daily intake of vitamin C is approximately 100 mg per day.

    Citrus fruits (orange, lemon, grapefruit), green vegetables (peppers, broccoli, cabbage), berries (black currants, strawberries, raspberries, blueberries, cranberries), melon, watermelon, kiwi, tomatoes and potatoes are champions in its content.

    It quickly collapses upon contact with air, metal utensils, high-temperature processing, drying and salting of fruits. An exception is sauerkraut, in which, if the integrity of the leaves is violated, vitamin C is additionally formed. Freezing usually does not cause its loss if the products are stored for a short time.

    At risk

    Serious vitamin C deficiency can be experienced by:

    • Infants whose mothers took it in large quantities during pregnancy
    • Smokers
    • People suffering from arthritis and arthrosis
    • Patients undergoing surgery
    • People taking non-steroidal anti-inflammatory drugs

    Ascorbic acid is prescribed during pregnancy for women at high risk of preeclampsia, which is characterized by high blood pressure and the presence of protein in the urine.

    The following diseases increase the need for vitamin C: AIDS, alcoholism, cancer, fever, intestinal diseases, overactive thyroid gland, peptic ulcer stomach, stress, tuberculosis, etc.

    Signs of vitamin deficiency

    Avitaminosis causes considerable harm to our health and appearance.

    Vitamin C is essential for the synthesis of collagen, which is used by the body to repair and regenerate skin, bones, teeth and cartilage.

    Signs of its deficiency:

    • dry hair and split ends
    • inflammation and bleeding of the gums
    • rough, flaky dry skin
    • nosebleeds
    • deterioration in the ability to memorize and perceive information
    • muscle weakness
    • joint pain
    • fatigue
    • bleeding gums
    • weakening of immunity

    Ascorbic acid is vital for children in the winter-spring period for vigorous tone, good memory and a healthy nervous system.

    polzovred.ru\u206a\u003e

    The benefits and uses of ascorbic acid

    Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that cannot be synthesized independently in humans. It is necessary that it comes with food, and if this amount is not enough, then it is recommended to take containing it medical drugs... Vitamin C influences many processes in the body.

    Immunomodulating action

    People with a cold are usually advised to consume as much vitamin C as possible. Ascorbic acid supports human immunity. It stimulates the synthesis of interferon, thanks to which cells can resist the virus that has entered the body. However, even when a person is not sick, he should not forget to take this vitamin, because it is good not only as a medicine, but also as a means of prevention.

    Benefits for metabolism

    Ascorbic acid plays an important role in metabolism. Thanks to it, serotonin, one of the main neurotransmitters, is formed from tryptophan. It is also involved in the synthesis of collagen and corticosteroids, the formation of cotesolamines. Ascorbic acid regulates the content of cholesterol in the body, stimulating its conversion to bile acids.

    Hematopoietic function

    Ascorbic acid is involved in the formation of hemoglobin. Thanks to her, the ferric iron that has entered the body is oxidized to bivalent. It is in this form that it can be used to carry oxygen.

    Antioxidant action

    Ascorbic acid is an antioxidant. It is able to neutralize superoxide radical, damaging cells, turning it into hydrogen peroxide, which is not dangerous for the body, in order to then safely remove it. Also, vitamin C regulates the course of redox reactions.

    How to use ascorbic acid

    Vitamin C is found in many foods. If you make sure that they are present in your diet, you are unlikely to experience a deficiency of this substance. Vegetables, fruits and berries are rich in ascorbic acid. It is found in cabbage, bell peppers, black currants, parsley, dill, kiwi, rose hips, mint, citrus fruits, and apples. It should be remembered that heat treatment destroys the vitamin. If you want to get the maximum dose of ascorbic acid, eat these foods raw. Vitamin C is present in small amounts in animal foods.

    Ascorbic acid is also available over the counter. It is produced in different forms, found in the form of pills, ampoules, tablets, powder. It often happens in combination with glucose, other vitamins, various micro- and macroelements. Adults are advised to consume 70-90 mg of ascorbic acid daily.

    KakProsto.ru\u206a\u003e

    What is the use of ascorbic acid?

    Vitamin C, or ascorbic acid as you call it, has a positive effect on the central nervous system, endocrine system and the absorption of iron. Also promotes hematopoiesis. But its most powerful effect on the body ascorbic acid is antioxidant. The use of ascorbic acid significantly reduces the formation of nitroelements.

    Sergey Ovsyannikov

    it is rich in vitamins C. The composition usually includes ascorbic acid, sugar, glucose, starch, (sometimes flavoring additives: mint, lemon orange, etc.)
    Contraindications: pregnancy, breastfeeding, diabetes mellitus, individual intolerance to the components.

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