Iodine testimony for use. Iodine alcohol solution: instruction and application

Iodine (LODUM)

Structure

Get out of ash sea algae and drilling oil waters. Suruterine with metal glitter plates or a severity of characteristic odor crystals. Flying at ordinary temperature; When heating is heated, forming violet pairs. Very little soluble in water (1: 5000), soluble in 10 parts of 95% of alcohol, soluble in aqueous solutions iodides (potassium and sodium). Incompatible S. essential oils, ammonia solutions, white precipitation mercury (an explosive mixture is formed).

pharmachologic effect

Provides antimicrobial action; By participating in the synthesis of thyroxine, affects the function of the thyroid gland, strengthens the dissembly processes (decay of complex organic substances to the simpler), is favorably affecting lipid and protein exchange.

Indications for use

Iodine preparations are used externally and inside; Outwardly used as antiseptic (disinfection), irritating and distracting means for inflammatory and other diseases of the skin and mucous membranes, inward - in atherosclerosis, chronic inflammatory processes In the respiratory tract, with tertiary syphilis, hyperthyroidism (thyroid disease), for the prevention and treatment of endemic goiter (thyroid disease due to a reduced iodine content in water), with chronic mercury poisoning and lead.

Mode of application

Outwardly in the form of 5% and 10% alcohol solution as an antiseptic (disinfection), irritating and distracting means. Inside of 0.02 g per reception in atherosclerosis, chronic inflammatory processes in the respiratory tract, with tertiary syphilis, hyperthyroidism (thyroid disease), endemic zob, chronic mercury poisoning and lead.

Side effects

Possible phenomena of iodiism (noncommunicable inflammation of mucous membranes in the locations of iodine in the overdose) or individual intolerance of iodine drugs - runny nose, urticaria, etc.

Contraindications

When taking inside: pulmonary tuberculosis, jade (kidney inflammation), furunculosis (multiple purulent inflammation skin), acne rashes, chronic piedermia (purulent skin inflammation), hemorrhagic diathesis (increased bleeding), urticaria, pregnancy, increased sensitivity To iodine.

Form release

Iodine crystalline; Alcohol 5% solution in bottles and ampoules 1 ml per pack of 10 pieces.

Storage conditions

In the light-protected place.

Active substance:

iodine

The authors

Links

• Official instruction for the drug iodine.
• Modern Medicines: Full practical guide. Moscow, 2000. S. A. Kryzhanovsky, M. B. Vittynova.

Attention!
Description of the drug " Iodine"This page is a simplified and supplemented version. official instruction for use. Before purchasing or using the drug, you should consult a doctor and familiarize yourself with the annotation approved by the manufacturer.
Information about the preparation is provided solely with an informational purpose and should not be used as a guide to self-medication. Only a doctor may decide on the appointment of the drug, as well as determine the doses and methods for its use.

Structure medicinal preparation Iodine

Active substance - iodine. Alcohol solution Contains iodine 5 g, iodide potassium 2 g, water and alcohol 95% equally up to 100 ml. pharmachologic effect

Dosage form

Substance plates

Pharmacotherapeutic group

Means containing iodine

Pharmacological properties

Pharmacological action - antiseptic, antimicrobial, distracting, hypolypidemic. Coagulates proteins with the formation of iodamins. Partially absorbed. The absorbed part penetrates the fabrics and organs, is selectively absorbed thyroid gland. It is highlighted by the kidneys (mainly), intestines, sweat and milky glands. It has a bactericidal action, has bubble and migration properties. Irritate skin and mucous receptors. Participates in the synthesis of thyroxine, strengthens the dissymimillation processes, is favorable on lipid and protein metabolism (decrease in cholesterol and LDL).

Iodine - indication for use

Inflammatory and other diseases of the skin and mucous membranes, abrasions, cuts, microtraums, mosites, neuralgia, inflammatory infiltrates, atherosclerosis, syphilis (tertiary), chronic atrophic laryngitis, ozen, hyperthyroidism, endemic goiter, chronic pioneractions lead and mercury; Disinfection of the skin of the operating field, edges of the Russian Academy of Sciences, the fingers of the surgeon.

Contraindications

Hypersensitivity; for intake - tuberculosis of the lungs, jade, furunculosis, acne, chronic piedermic, hemorrhagic diathesis, urticaria; pregnancy, childhood (up to 5 years).

Cautions when used

With a combined application with yellow mercury ointment, it is possible to form in the tear fluid of the mercury iodide, which has an ignition effect.

Medicinal interaction

Pharmaceutically incompatible with essential oils, ammonia solutions, white precipitation mercury (an explosive mixture is formed). Weakens the hypothyroid and streaming effect of lithium preparations.

Side effects

Iodiism (runny nose, skin rashes by the type of urticaria, salivation, tearing, etc.).

Overdose

When inhalation of vapors - the defeat of the upper respiratory tract (burn, laryngobronchospasm); In case of concentrated solutions, heavy burns digestive tract, the development of hemolysis, hemoglobinuria; lethal dose It is about 3 g. Treatment: washed with a stomach with a 0.5% sodium solution of thiosulfate, in / in sodium thiosulfate is injected with 30% - up to 300 ml.

Iodine (iodine)

Composition and form of release of the drug

Auxiliary substances: ethanol 95%.

10 ml - dark glass vials (1) - packs cardboard.
15 ml - dark glass vials (1) - packs cardboard.
25 ml - Dark Glass Vials (1) - Cardboard packs.
100 ml - Dark Glass Vials (1) - Cardboard packs.

pharmachologic effect

Elementary iodine has pronounced antimicrobial properties. For elementary iodine preparations, a pronounced locally radiant effect on fabric, and in high concentrations, an ignition effect. Local action is due to the ability of elementary iodine to precipitate tissue proteins. Preparations that scrapping elementary iodine have a significantly less pronounced irritant effect, and iodides have local radiant properties in very high concentrations.

Pharmacokinetics

In contact with the skin or mucous membranes, it turns into iodide by 30%, and the rest is in active iodine. Partially absorbed. The absorbed part penetrates the tissues and organs, is selectively absorbed by the thyroid gland. It is highlighted mainly by the kidneys, intestines, sweat and milk glands.

Indications

For outdoor use: infectious and inflammatory lesions of the skin, injury, wounds, Malgia.

For local application: chronic tonsillitis, atrophic rhinitis, purulent, trophic and varicose sores, wounds, infected burns, fresh thermal and chemical burns of the I-II degree.

Contraindications

Increased sensitivity to iodine.

Dosage

With external use of iodine, damaged skin sections are treated.

Locally used for washing lacuna and supratonzillary spaces - 4-5 procedures with intervals of 2-3 days, for irrigation of the nasopharynx - 2-3 times a week for 2-3 months, for injection in ear and washing - within 2-4 weeks; In surgical practice and are wetted as the gauze napkins superimposed on the affected surface needed.

Side effects

With outdoor use: rarely - skin irritation; for long use On extensive wound surfaces - iodiism (rhinitis, urticaria, swelling of quinque, saliva, tearing, acne).

Medicinal interaction

Pharmaceutically incompatible with essential oils, white precipitation mercury (an explosive mixture is formed). Alkaline or acidic medium, the presence of fat, pus, blood weakens antiseptic activity.

Iodine coagulates proteins with the formation of iodamins. It has a bactericidal impact, also has migration and twin properties. Irritic to the receptors of mucous membranes and skin. Participates in the formation of thyroxin. During contact with leather or mucous membranes, it turns into iodide by 30%, the rest turns into an active iodine. Iodine is partially absorbed. The absorbed part enters the organs and fabrics. The most pronounced effects of the drugs of iodine are on the thyroid gland. If iodine deficiency in the body is help to restore the impaired formation of thyroid hormones. In the content of iodine in the body in normal quantities Inhibits the formation of thyroid hormones, reduces the sensitivity to tong pituitary gland and blocks the secretion of TSH pituitary. The effect of the drugs of iodine on metabolism is manifested by an increase in dissimulation processes. In atherosclerosis, they lead to a certain decrease in the content of beta lipoproteins and cholesterol in the blood; Also increase the lipoproteinas and fibrinolytic activity of blood serum and the blood coagulation rate is inhibited. The iodine contributes to the resorption and softening of syphilitic gum when accumulating in them. But when the iodine accumulation in the foci of tuberculosis leads to an increase in inflammation processes in them. When the iodine is released by excretory glands, iron fabric is irritated and secretion is enhanced. This causes lactation stimulation (in small doses) and an expectorant effect. But in large doses, iodine can coagulate lactation. Basically stands out by the kidneys, to a lesser extent in the intestine, dairy and sweat glands.

Indications

Inflammatory and other diseases of the mucous membranes and skin; cuts; abrasions; microtrauma; neuralgia; Mositis; atherosclerosis; inflammatory infiltrates; syphilis (tertiary); ozen; chronic atrophic laryngitis; endemic goiter; hyperthyroidism; chronic mercury poisoning and lead; Disinfection of the edges of the Russian Academy of Sciences, the skin of the operating field, the fingers of the surgeon.

The use of iodine and dose

Outwardly apply to the affected areas of the skin, larynx, in a conjunctival bag (3 times a day 1 drop), bury the nose (2 times a day of 5 drops). Inside, dilute in milk, after eating, during atherosclerosis -1-2 times a day for 4 weeks of 5-12 drops, repeated courses (2-3 times per year), during syphilis -2-3 times a day at 5 -50 drops, children -2-3 times a day for 3-5 drops of 5% solution.
When you pass the next iodine reception, take it as remember next reception Create after the set time from last use.
When used with yellow mercury ointment, it is possible to form a mercury iodide in a tear fluid, which has an ignition effect. With prolonged use, phenomena of iodiism are possible.

Contraindications for use

Hypersensitivity, for intake: jade, pulmonary tuberculosis, furunculese, chronic pyodermium, acne, urticaria, hemorrhagic diathesis, adenoma (including thyroid gland), age up to 5 years, pregnancy.

Restrictions on application

No data.

Application in pregnancy and breastfeeding

The use of iodine is contraindicated during pregnancy. When breastfeeding, it is possible to use the testimony when prescribed by the doctor.

Side effects of iodine

With outdoor use:skin irritation; With prolonged use on large surfaces - iodiism (rhinitis, tearing, sneaking of quinque, urticaria, saliva, acne).
When taking inside: Tachycardia, skin allergic reactions, nervousness, increased sweating, sleep disorders, diarrhea.

Iodine interaction with other substances

Iodine is pharmaceutically incompatible with sedimentary white mercury (an explosive mixture is formed), ammonia solutions, essential oils. An acidic or alkaline medium, the presence of pus, fat, blood reduces the antiseptic activity of iodine. The iodine reduces the structured and hypothyoid effect of lithium drugs.

Overdose

When inhalation of the vapor of iodine, the upper respiratory tract (laryngochospasm, burn) arises; In addition to the concentrated Iodium solutions, severe bows of the digestive tract arise, the development of hemoglobinuria, hemolysis; The deadly dose equals approximately 3 g. Treatment: washing the stomach 0.5% solution of sodium thiosulfate, intravenous administration Sodium thiosulfate 30% - up to 300 ml.

Composition and form of release of the drug

◊ Solution for outdoor use of alcohol 5% Transparent, red-brown color, with a characteristic smell.

Auxiliary substances: ethanol 95%.

10 ml - bottles.
15 ml - bottles.
25 ml - bottles.

pharmachologic effect

Elementary iodine has pronounced antimicrobial properties. For elementary iodine preparations, a pronounced locally radiant effect on fabric, and in high concentrations, an ignition effect. Local action is due to the ability of elementary iodine to precipitate tissue proteins. Preparations that scrapping elementary iodine have a significantly less pronounced irritant effect, and iodides have local radiant properties in very high concentrations.

Pharmacokinetics

When contacting the skin or mucous membranes, it turns into iodide by 30%, and the rest is in active iodine. Partially absorbed. The absorbed part penetrates the tissues and organs, is selectively absorbed by the thyroid gland. It is highlighted mainly by the kidneys, intestines, sweat and milk glands.

Indications

For outdoor use: infectious and inflammatory lesions of the skin, injury, wounds, Malgia.

For local applications: chronic tonsillitis, atrophic rhinitis, purulent, trophic and varicose ulcers, wounds, infected burns, fresh thermal and chemical burns of the I-II degree.

Contraindications

Increased sensitivity to iodine.

Dosage

With external use of iodine, damaged skin sections are treated.

Locally used for washing lacuna and supratonzillary spaces - 4-5 procedures with intervals of 2-3 days, for irrigation of the nasopharynx - 2-3 times a week for 2-3 months, for injection in ear and washing - within 2-4 weeks; In surgical practice and are wetted as the gauze napkins superimposed on the affected surface needed.

Side effects

With outdoor use: rarely - skin irritation; With long-term use on extensive wound surfaces - iodiism (rhinitis, urticaria, swelling of quinque, saliva, tearing, acne).

Medicinal interaction

Pharmaceutically incompatible with essential oils, white precipitation mercury (an explosive mixture is formed). Alkaline or acidic medium, the presence of fat, pus, blood weakens antiseptic activity.