Biltricide side effects. What worms does Biltricide treat? Calculating the number of tablets for a single dose

Instructions for use:

Composition and form of release

Biltricid is produced in the form of film-coated tablets. The main active ingredient each tablet contains 600 mg of praziquantel. Auxiliary components of the preparation: microcrystalline cellulose, corn starch, sodium lauryl sulfate, titanium dioxide, macrogol 4000, magnesium stearate, hypromellose, povidone.

In dark glass vials, 6 pcs.

Indications for the use of Biltricid

According to the instructions, Biltricide is prescribed for the treatment of infections caused by all kinds of schistosomes (Schistosoma mekongi, Schistosoma intercalatum, Schistosoma haematobium, Schistosoma japonicum, Schistosoma mansoni), as well as those caused by hepatic flukes (Opistorchis viverrini, Clonorchis sinus) and fluke

Contraindications

The use of Biltricid is contraindicated in the following cases:

• Hypersensitivity to the main or auxiliary components of the drug;
• Children up to age four;
• In combination with rifampicin;
• Cysticercosis of the eyes.

According to reviews, Biltricide should be prescribed with caution in cardiac arrhythmias, hepatolienal schistosomiasis, decompensated liver failure.

Method of application of Biltricid and dosage regimen

According to the instructions, Biltricid is intended for oral administration. The tablet is taken whole, without chewing, with a little water. Reception should be carried out shortly before or immediately during a meal. If the recommended dosage of Biltricid is 1 tablet per day, then it is better to take it in the evening. If the use of Biltricid is repeated throughout the day, then an interval of 4-6 hours must be observed between taking the tablets.

Biltricid dosages are set individually, depending on the type of pathogen.

According to the instructions, Biltricid is prescribed for children over four years of age and for adults in the following dosages:

• Single dose of 40 mg / kg body weight for infections caused by Schistosoma haematobium;
• 20 mg / kg twice a day or 40 mg / kg body weight once for infections caused by Schistosoma intercalatum and Schistosoma mansoni;
• 30 mg / kg body weight twice a day or 60 mg / kg once for infections caused by Schistosoma japonicum, Schistosoma mekongi;
• At 25 mg / kg body weight three times a day for 1-3 days for infections caused by Clonorchis sinensis, Opisthorchis viverrini, Paragonimus westermani.

The use of Biltricid during pregnancy and breastfeeding

According to reviews, Biltricide is not recommended to be prescribed in the first trimester of pregnancy. Since praziquantel penetrates into breast milk, for the period of taking Biltricid breast-feeding it is recommended to suspend, as well as on the next day after the end of the drug intake.

Side effects

According to reviews, Biltricide can cause the following side effects:

• Cardiovascular system: arrhythmia.
• Digestive system: vomiting, nausea, abdominal pain, bloody diarrhea, loss of appetite.
• Musculoskeletal system: myalgia.
• Central nervous system: dizziness, headache, convulsions, drowsiness.
• Allergic reactions: urticaria, generalized allergic reactions, including polyserositis.
• Other side effects: fever, asthenia.

Biltricide drug interactions

When Biltricide is combined with anticonvulsants, drugs that induce liver enzymes of the cytochrome P450 system, dexamethasone, a decrease in the concentration of the main component of Biltricide in the blood plasma may occur. When Biltricide is combined with drugs that inhibit liver enzymes of the cytochrome P450 system, the concentration of praziquantel may, on the contrary, increase in blood plasma.

The simultaneous use of Biltricide and chloroquine leads to a decrease in the level of praziquntel in the blood plasma.

Storage conditions

According to the instructions, Biltricid belongs to List B drugs with a recommended shelf life of 5 years.

Which we have not heard or heard for the first time. It is often very difficult to find the right medicine for different parasites () due to side effects... Biltricide is one of the easiest to use drugs, and we suggest considering the instructions for its use.

Biltricide relieves the body of various types of schistomas, various types of feline fluke.

The drug is easily and completely absorbed into the bloodstream in the gastrointestinal tract immediately after ingestion. This agent is excreted from the body by the kidneys, the main part of the substance leaves the patient's body within 24 hours after ingestion.

You need to know that before using Biltricide, it is imperative to pass tests and identify the degree of infection, as well as the type of helminth infection.

Composition and release forms

The package contains six tablets, which are packaged in dark glass bottles. Since the main medicinal substance in the composition of Biltricin is, each tablet of this substance contains 600 mg.

But this drug also contains auxiliary substances that are part of the drug, such as: magnesium stearate, macrogol 4000, microcrystalline cellulose, sodium lauryl sulfate, hypromellose, corn starch, titanium dioxide and povidone.

Indications for admission

The drug Biltricid is released in the form of tablets, which are prescribed to be taken orally during meals or before meals, without chewing, it is recommended to drink a small amount of water. When prescribing the drug once a day, it is advisable to take the pill at night. It is possible to prescribe multiple doses, in such cases it is worth observing a maximum of long intervals between doses of the medication 4-6 hours.

Instructions for use in the treatment of helminths with the drug Biltricid

For each patient, the dosage is calculated individually, mainly depending on the complexity of the disease. Read the instructions for use carefully.

This medicine allowed for adults and children over four years old

The drug is taken on an outpatient basis, but with the obligatory prescription of a doctor.

Application and dosage of biltricide for opisthorchiasis

When treating with this drug, the dosage is necessarily calculated based on one kilogram of mass, 25 mg of the drug is prescribed.

Treatment depends on the severity of the disease, mainly prescribed to take three times a day in a course of 1-3 days.

Instructions for use with schistosomas

During treatment different types Schistosom Biltricid is drunk once a day by mouth, 40 mg.

Basically, the duration of taking the drug is only one day, in some cases, repeated treatment is necessary after a couple of weeks, when the invasion has not completely disappeared.

In the gastrointestinal tract:

• colic;
• pain and cramps in the abdomen
• nausea, gag reflex;
• violation of digestion and appetite;
• diarrhea.

In the central nervous system:

• headache;
• dizziness;
• general weakness;
• feeling drowsy;
• convulsions;
• fever;
• arrhythmia.

Allergic reactions are most often accompanied by rashes on the skin, urticaria.

Biltricide side effects

It is not considered advisable to cancel the drug with various side effects, the reason for stopping treatment with this drug is only a very pronounced side effect. To accept another medicinal substance, you definitely need a doctor's consultation.

Especially important! If there are contraindications, the drug is prohibited to use.

Contraindications

• Children under the age of four should not take Biltricid, since the safety of this drug for small children has not been established.
• During pregnancy in the first trimester, it is not advisable to use this remedy.
• Breastfeeding should be discontinued during the course of drug therapy.
• Do not take the drug Biltricide with remedy Rifampicin.
• Doctors prohibit the use of Biltricin for cysticercosis of the eyes.
• And also in case of kidney disease, renal failure, this drug should be taken with extreme caution, in special cases it is recommended to take inpatient treatment.

Patients with heart disease, heart rhythm disorders, need to undergo a course of drug treatment under the guidance of a doctor.

In difficult cases, it may be necessary to undergo a course of treatment in a hospital, but this depends on concomitant diseases, as well as on the place of residence of the patient, since some regions are endemic for trematodosis.

It is recommended to restrict driving of any vehicle while taking the drug, as the drug can negatively affect concentration. It is not advisable to consume alcohol or alcoholic beverages during treatment with this remedy.

Biltricide analogs

Biltricid, like other drugs, has direct and indirect analogs with similar effects. It must be said that even with a great similarity, the analogs in any case differ from this drug, it is worth noting that when choosing a drug, you should remember this.

Azinox tablets are the main analogue of this drug, because it is based on. These drugs fight severe types and.

This drug is equal to Biltricid in its basic properties.

Whatever one may say, but Azinoks has much more contraindications: it is forbidden for liver disease and pregnant women. Recommended when choosing medicinal product consult with your doctor and rely on the results of tests, examinations.

Biltricide is a praziquantel-based drug produced (and developed) by the pharmaceutical company Bayer AG. Although there are almost two dozen abroad trade names praziquantel, in the territory of the post-Soviet space, only Biltricide is sold, therefore, purchase more cheap analog this drug will fail.

Since praziquantel is included in the list of essential medicines approved by the government of the Russian Federation, you can buy it in almost every pharmacy. Officially, the drug is dispensed with a doctor's prescription, but due to the fact that Biltricid is not included in the list of drugs subject to quantitative accounting, it is usually sold without a prescription. A bottle with six 600-milligram tablets costs about 300 rubles.

Indications for taking Biltricid

Praziquantel has a protivocestodoznogo and protivotrematodozny effect, i.e. capable of killing flatworms from the class of cestodes (tapeworms) and trematodes (digenetic flukes).

According to instructions, full list helminthiasis that can be treated with praziquantel include:

• cysticercosis (helminth pathogens - pork tapeworm larvae);
• teniasis (pork tapeworms);
• teniarinhoz (bovine tapeworms);
• hymenolepiasis (dwarf tapeworms);
• diphyllobothriasis (broad tapeworms);
• schistosomiasis (schistosomes);
• fasciolopsis (fasciolopsis);
• fascioliasis (hepatic and giant flukes);
• opisthorchiasis (Siberian fluke);
• clonorchiasis (Chinese fluke);
• metagonimosis (metagonims);
• paragonimiasis (pulmonary flukes).

However, as the experience of doctors around the world shows, praziquantel can also be used to treat the following helminthiasis:

• dicroceliosis (lanceolate fluke);
• nanofietosis (nanofietus);
• dipylidiosis (cucumber tapeworms);
• sparganosis (larvae of Spirometra erinaceieuropaei).

Infection for the most part of these occurs only when poorly processed mammalian meat or fish are consumed. Given the growth in medical literacy of the population, such cases are becoming less and less, and drug prevention is not required here - only "targeted" treatment of diagnosed helminthiasis.

Nevertheless, cestodoses and trematoses have common characteristic symptoms, the presence of which may become a reason for taking tests or even immediate treatment.

Typical symptoms of a tapeworm infection:

As for liver flukes, it is impossible to diagnose infection with them at home.

Dosage and treatment regimen with Biltricide

Treatment with Biltricide of dicroceliosis and dipylidiosis has not been developed, but the likelihood of contracting these helminthiases is extremely small.

Praziquantel is considered a highly toxic drug that has a negative effect on the human liver. Therefore, it is usually not applied:

• with liver diseases;
• in the first trimester of pregnancy;
• under the age of 4.

Correctly calculated single dose of Biltricide, sufficient to remove the tapeworm, as a rule, does not cause serious "side effects". However, large doses required to treat trematodes often provoke the following side effects:

• lethargy;
• disorientation;
• migraine;
• drowsiness;
• itching and skin rash;
• heavy sweating;
• nausea;
• vomiting;
• stomach ache;
• diarrhea with blood;
• increased activity of liver enzymes.

Due to the toxicity of Biltricide, it is highly undesirable to use it without the consent of a doctor due to possible consequences for the liver. Moreover, large worms from the class of tapeworms are perfectly excreted by folk remedies, therefore, even with the appointment of Biltricid by a doctor, it is worth first testing the following folk anthelmintics:

In order to remove hepatic flukes, tinctures, decoctions or purchased extracts from aspen bark are used.

When there is no cooking time folk remedies they can be replaced with ready-made multicomponent preparations from antiparasitic plants.

Latin name: BILTRICIDI
International name:Praziquantel
ATX code: P02BA01
Active substance: Praziquantel
Manufacturer: Bayer Schering Pharma,
Germany
Pharmacy dispensing condition: On prescription

Composition of the preparation

The drug consists of 600 mg of praziquantel and excipients: corn starch, cellulose, polyvinylpyrrolidone, sodium lauryl sulfate, magnesium stearate, hypromellose, etc.

Healing properties

Indications for use

Praziquantel is prescribed for the following pathologies:

• Neurocysticercosis
• Fasciolopsidosis
• Trematodosis
• Genitourinary schistosomiasis
• Intestinal form of schistosomiasis
• Fascioliasis
• Cysticercosis
• Cestodosis.

Price about 400 rubles

In addition, Biltricide can also successfully fight diphyllobothriasis, which is caused by tapeworms. With diphyllobothriasis, the efficiency of removing worms is about 95%. Also, a disease such as opisthorchiasis must be treated with praziquantel. Positive dynamics is observed in almost 85% of patients.

Release forms

Biltricid is available in the form of 600 mg coated tablets. Glass bottle with plastic stopper, contains 6 tablets. The bottle is in a cardboard box, along with instructions.

Mode of application

Biltricid tablet should be taken before or during a meal with the required amount of water, not chewed. If the medicine needs to be taken once a day, it is better to do it in the evening. If it is necessary to take the tablets several times, then the interval between doses should be at least 4 hours.

The treatment regimen for opisthorchiasis consists of 75 mg per 1 kg of body weight.

The therapeutic course is carried out under the obligatory supervision of a physician; at home, it is never permissible to carry out treatment at home. How many pills to drink is determined by a specialist, for each patient taking pills is individual. This often depends on the type of disease and its severity.

Pregnancy and breastfeeding

Biltricide is contraindicated during pregnancy, especially in the first trimester of pregnancy. It is also prohibited for women who feed a baby, since the substance actively penetrates into the mother's milk.

Contraindications and precautions

Biltricide is contraindicated in such cases:

• Hypersensitivity to the drug
• Cysticercosis of the eye
• Pregnancy and lactation
• Childhood.

With extreme caution, Biltricide treatment is carried out in patients with renal failure, heart rhythm disturbance, with hepatolienal schistosomiasis. Laxatives are not necessary while using this drug. Praziquantel may affect vehicle control and concentration.

Interaction with other medications

The effectiveness of the drug is significantly reduced when used simultaneously with dexamethasone.

Liver indicators lower the concentration of the drug in the blood.

Liver inhibitors increase the concentration of the active substance.

Side effects

In some cases, Biltricide can cause such side effects:

• From the gastrointestinal tract: stomach pain, attacks of nausea, bloody diarrhea, sometimes vomiting
• From the side nervous system: headaches, drowsiness, dizziness, in rare cases - convulsions
• From the musculoskeletal system: myalgia
• From the side of cardio-vascular system: heart rhythm disturbances
• From the side skin: urticaria, itching.

In rare cases, it is possible allergic reaction, malaise, fever.

Overdose

To date, no data is known about an overdose of Biltricide. Experts suggest that if the dose is significantly exceeded, side effects may increase.

Conditions and shelf life

Store the medicine in a dry, dark place, at a temperature not exceeding 25 degrees Celsius. The shelf life is 2 years.

Analogs

"Azinox"

Ecohimtech LLC, Russia
Price 350 rbl

Pros:

Minuses:

• The drug is not allowed in childhood
• There are side effects.

"Vermox"

Gedeon Richter JSC, Romania
Price 140 rbl

Pros:

• Wide spectrum of action
• Quite low cost

Minuses:

• Effective for enterobiasis and trichocephalosis, with other ailments, the drug acts to a lesser extent
• A considerable number of side effects and contraindications.

"Pirantel"

Pharmatekhnologiya, LLC, Republic of Belarus
Price 40 rbl

An anthelmintic drug is used for nematodes. Appointed for ascariasis, enterobiasis, ankylostomiasis, opisthorchiasis. A medication is produced in the form of tablets and suspension for oral administration.

Pros:

• Well tolerated by patients
• Fairly acceptable cost

Minuses:

• Lots of side effects
• The drug is contraindicated in patients with impaired liver and kidney function.

In the pharmacy, the drug "Biltricid" can be purchased in the form of oblong, biconvex tablets white, sometimes with a slight yellowish or orange tinge. The tablets are placed in dark glass bottles of 6 pieces. The main active ingredient of the drug is praziquantel - each tablet contains about 600 mg of this substance. As for the auxiliary components, the composition of the drug contains magnesium stearate, macrogol 4000, microcrystalline cellulose, hypromellose, corn starch, and povidone.

Indications for admission

This medicine is indicated in the treatment of helminthic diseases, such as, for example, opisthorchiasis. Treatment with "Biltricid" helps with infection of the human body different kinds schistosome. Indications for therapy are diseases caused by hepatic and some other types of helminths.

The drug "Biltricid": instructions for use

In no case should the medicine be used arbitrarily. Only a doctor after a thorough diagnosis can prescribe treatment with Biltricid. The instructions for use contain only general recommendations.

The tablet should be swallowed without chewing, with a little water. It is recommended to take the drug before or during meals. If the medicine needs to be drunk once a day, it is best to do it in the evening.

Description of contraindications and side effects

For many patients with helminthiasis, doctors prescribe the drug "Biltricid". Its analogs, by the way, are more toxic. Despite the fact that the drug acts sparingly on the body, there are still some restrictions. In particular, it is not prescribed for children under four years of age, as well as for women in the first trimester of pregnancy. Contraindications include cysticercosis of the eyes, allergy to the constituent components of the drug. Therapy should not be combined with rifampicin. The medicine is used with caution in the presence of cardiac arrhythmias, decompensated form of liver failure, hepatolienal schistosomiasis.

The drug "Biltricid": analogues

This medicine is quite popular in modern medical practice... On the other hand, the drug Biltricid is not suitable for all patients. Naturally, there are analogues of this remedy. For example, in some cases, doctors prescribe drugs such as "Medamin", "Levamisole", "Helmintox". In the fight against helminths can be used and such means as "Nemozol", "Zentel", "Dekaris", "Mebendazole" and some others. In any case, it must be remembered that only the attending physician can prescribe an analogue.