Terms and definitions for computed tomography of the kidneys. Column bertini kidney what is fetal lobulation

Kidney tumors account for 2-3% of all malignant neoplasms. Most often they occur at the age of 40-60 years. Renal cell carcinoma is noted in 80-90% of all kidney tumors. IN last years the probability of its detection increases, which is associated with both an increase in the number of all malignant tumors and early preclinical diagnosis. To recognize malignant tumors, first of all, it is possible to constantly improve and widely used ultrasound studies of the kidneys.

The first report on the use of ultrasound in the diagnosis of kidney tumors was published in 1963 by J. Donald. Since then, the accuracy of ultrasound diagnostics of kidney tumors has increased from 85-90% to 96-97.3%. When using modern tissue and second harmonic modes, as well as color Doppler and dynamic echocontrast angiography, the sensitivity of ultrasound (US) is 100% with a specificity of 92 and predictability of a positive test of 98%, and a negative one of 100%.

In the literature, there are often publications devoted to errors not only of ultrasonic, but also of other methods. radiation diagnostics... There is a point of view that up to 7-9% of all volumetric processes in the kidneys cannot be differentiated prior to operations for cysts, tumors, abscesses, etc. ... The picture of a kidney tumor with ultrasound and other radiation diagnostic methods can simulate many processes. Among them: various kidney anomalies; "complex" or mixed cysts; acute and chronic nonspecific inflammatory processes (carbuncle, abscess, chronic, including xanthogranulomatous pyelonephritis); specific inflammatory processes (tuberculosis, syphilis, fungal infections of the kidneys); changes in the kidneys with leukemia and lymphomas, including HIV infection; kidney infarction; organized hematomas and other reasons.

In this message, we will only talk about kidney abnormalities, which in the literature are defined by the term pseudotumor. With them, clinical manifestations are almost always absent or determined by concomitant diseases, and the establishment of the correct diagnosis is possible only by methods of radiation diagnostics (Fig. 1).

Figure: one. Variants of pseudotumors that mimic a tumor.

and) Fetal groin, "humped" kidney.


b) Bertin's pillar hypertrophy, enlarged "lip" over the hilum.

Materials and methods

1992-2001 observed 177 patients with different structures of the renal parenchyma by the type of renal pseudotumors. All of them repeatedly underwent ultrasound scanning of the kidneys, ultrasound dopplerography (USDG) of the vessels of the kidneys - 78, including using modes of the second and tissue harmonics and - 15, excretory urography (EU) - 54, X-ray computed tomography (CT) - 36, renal scintigraphy or emission computed tomography (ECT) with 99 m Tc - 21.

Research results

Fetal lobulation of the kidney (see Fig. 1) with multiple bulging along the lateral contour of the kidney was not considered in this report, since it did not cause the need differential diagnosis with a kidney tumor. Among 177 patients with pseudotumors of the kidneys, 22 (12.4%) had a variant of a lobular kidney - a "humped" kidney (Fig. 2).

Figure: 2. Pseudotumor "humped" left kidney.

and) Echograms.

b) A series of computer tomograms.

In 2 (1.2%) patients, an enlarged "lip" was noted above the hilum of the kidney (Fig. 3a-c).

Figure: 3 (a-c). Pseudotumor enlarged "lip" of the kidneys on both sides.

and) Echogram.

b) Excretory urogram.

in) Contrast-enhanced CT.

The most common cause of pseudotumor was "hypertrophy" of Bertin's pillars or "bridge" of the renal parenchyma - in 153 (86.4%) patients (Fig. 3d-f). "Bridges" of the parenchyma were noted not only with various doubling of the renal calyceal systems, but also with their various adhesions and incomplete turns of the kidneys.

Figure: 3 (d-f). Pseudotumor Bertin's hypertrophy (incomplete "bridge" of the parenchyma) in the middle section of the right kidney.

d) Echogram.

e) Excretory urogram.

e) Contrast-enhanced CT.

Differential diagnosis of pseudotumors and renal tumors required 37 (21%) patients. For this purpose, first of all, repeated "targeted" ultrasound scans were carried out using various additional ultrasound techniques in a urological clinic, as well as other methods of radiation diagnostics mentioned above. Only one patient with pseudotumor of the kidney underwent explorative lumbotomy with intraoperative ultrasound-guided biopsy to exclude the diagnosis of a tumor. In the remaining 36 patients, the diagnosis of pseudotumors of the kidneys was confirmed by radiation studies and ultrasound monitoring.

Difficulties and errors in radiological diagnosis in pseudotumors of the kidneys usually occurred at the first prehospital stages diagnostics. In 34 (92%) patients, they were associated with both objective difficulties in interpreting unusual echographic data and their incorrect interpretation due to insufficient qualifications of specialists and a relatively low level of diagnostic equipment. In 3 (8%) patients, an erroneous interpretation of X-ray computed tomography data was noted, when a discrepancy was noted with the data of repeated ultrasound scans and X-ray computed tomography in a urological clinic.

Tumors of the kidneys, which had their combinations with a pseudotumor in one kidney, were verified in 2 patients after nephrectomy, and pseudotumors - in one patient with biopsy under ultrasound control during exploratory lumbotomy; for the rest - with ultrasound monitoring over a period of 1 to 10 years.

Discussion

One of the most common reasons for simulating a kidney tumor on ultrasound, the so-called pseudotumor, is most often defined in the literature as Bertin's pillar hypertrophy.

As you know, along the periphery of the ultrasound cut of the kidney, the cortex forms intussusceptions in the form of pillars (columnae Bertin) between the pyramids. Often, Bertin's pillar goes deep enough beyond the inner contour of the parenchyma into the central part of the kidney - into the renal sinus, dividing the kidney more or less completely into two parts. The resulting peculiar parenchymal "jumper" is the non-absorbed parenchyma of the pole of one of the lobules of the kidneys, which merge into the kidney of an adult during ontogenesis. The anatomical substrate of the "bridges" is the so-called connective tissue defects of the parenchyma or prolapse of the latter into the sinus of the kidney. It includes cortical substance, Bertin's pillars, kidney pyramids.

All elements of the "bridge" are normal parenchymal tissue without signs of hypertrophy or dysplasia. They represent a doubling of the normal renal cortex or its additional layer located lateral to the calyx. The latter is a variant of the anatomical structure of the parenchyma, in particular, the corticomedullary relationship between the parenchyma and the renal sinus. They can be most clearly seen on ultrasound and computed tomographic sections of the kidney.

The absence of parenchymal hypertrophy or dysplasia in the so-called hypertrophy of Bertin's pillars or parenchymal "bridges" was confirmed by histological examinations biopsy material in one patient with parenchymal "bridges", taken before explorative lumbotomy for a kidney tumor, as well as in two patients with a morphological study of the kidneys removed due to a combination of tumor and pseudotumor in one kidney (parenchyma "bridges").

In this regard, in our opinion, the term most frequently encountered in the literature, the term hypertrophy of Bertin's pillars does not reflect the morphological essence of the substrate. Therefore, we, like a number of authors, believe that the term "jumper" of the parenchyma is more correct. For the first time in the domestic literature on ultrasound diagnostics, we applied it in 1991. It should be noted that the term "jumper" of the parenchyma had other names in the literature (table).

Table... Terms used to describe the "bridges" of the renal parenchyma (according to Yeh HC, Halton KP, Shapiro RS et al., 1992).

Origin or nature of the fabric Terms Authors
Hypertrophied or unusually wide tissue Hypertrophied Bertin's pillar Lafortune M et al., 1986
Wolfman NT et al., 1991
Leekman RN et al., 1983
Focal cortical hyperplasia Popky GL et al., 1969
Wide arcade Hodson CJ et al., 1982
Misplaced or misplaced fabric Lobar dysmorphism Carghi A et al., 1971
Dacie JE, 1976
Incorrect position of the renal lobe Carghi A et al., 1971
Cortical folds King MC et al., 1968
"Kidney" within the kidney Hodson CJ et al., 1982
Cortical invagination and prolapse of Bertin's pillars Lopez FA, 1972
Mass or pseudo-mass Renal pseudotumor Felson B et al., 1969
Lopez FA, 1972
Glomerular zone of pseudotumor Hartman GW et al., 1969
Renal cortical nodule Wolfman NT et al., 1991
Primary cortical nodule Thornbury JR et al., 1980
Intermedial cortical mass Netter F et al., 1979
Fetal anomaly Aberrant lobule of renal tissue Meaney TF, 1969
Benign Cortical Caesura Flynn VJ et al., 1972
Cortical islet of the kidney Flynn VJ et al., 1972
Evolved (perfect) anomaly Failed attempt to duplicate renal parenchyma Dacie JE, 1976
Supernumerary share Additional renal lobe Palma LD et al., 1990

Long-term experience of excretory urography has shown that the calyx-pelvic systems have an extremely large number of structural options. They are practically individual not only for each person, but also for the left and right kidneys in one subject. With the development and increasingly widespread use of ultrasound and CT, which makes it possible to trace both the internal and external contours of the renal parenchyma, in our opinion, a similar situation is developing with respect to the variants of the anatomical structure of the renal parenchyma. Comparison of echo and computed tomographic data with urographic data for various types of renal pseudotumors showed that there is a relationship between the anatomical structure of the parenchyma and the renal calyx systems. It is expressed in the congruence of the medial contour of the parenchyma in the echo or computed tomographic image with the lateral contour of the calyceal-pelvic systems, conventionally performed on excretory urograms or on computed tomograms with contrast enhancement. This symptom can be traced in the usual structure of the parenchyma and calyx-pelvic systems, as well as in the "bridge" of the kidney parenchyma, which is a variant of the anatomical structure. In a kidney tumor, which is an acquired pathological process, the congruence of the contours of the parenchyma and renal calyx systems is disturbed (Fig. 4).


Figure: 4. A symptom of the congruence of the contours of the parenchyma and the renal calyx-pelvis with an incomplete "bridge" of the parenchyma (explanation in the text).

findings

Thus, the typical ultrasound images of the "bridge" of the kidney parenchyma, "humpback" kidney and an enlarged "lip" above the hilum of the kidney without signs of expansion of the calyceal-pelvic systems do not require further examination.

If a differential diagnosis of pseudotumors and renal tumors is required, which was required in 37 (21%) patients, we propose the following diagnostic algorithm (Fig. 5).

Figure: five. Algorithm of radiological diagnosis for pseudotumor of the kidney.

  1. Repeated ultrasound by qualified specialists of a higher class using ultrasound, mapping techniques, tissue and second harmonics.
  2. X-ray computed tomography with contrast enhancement or excretory urography with comparison of uro- and echographic data and data of repeated "targeted" ultrasound.
  3. The methods of choice are renal scintigraphy or emission computed tomography with 99 m Tc (false-negative results are possible in small tumors).
  4. With the remaining suspicions of a malignant tumor, a biopsy under ultrasound guidance (only a positive result is of diagnostic value).
  5. If the biopsy result is negative or the patient refuses biopsy and operative revision of the kidney, ultrasound monitoring is performed at a frequency of at least once every 3 months in the first year of observation, and then 1-2 times a year.

Literature

  1. Demidov V.N., Pytel Yu.A., Amosov A.V. // Ultrasound diagnostics in urology. M .: Medicine, 1989. S. 38.
  2. Hutschenreiter G., Weitzel D. Sonographic: einewertwolle erganzung der urologichen Diagnostic // Aktuel. Urol. 1979. Vol. Bd 10 N 2. P. 45-49.
  3. Nadareishvili A.K. Diagnostic capabilities of ultrasound in patients with kidney tumor // 1st Congress of the Association of Specialists of Ultrasound Diagnostics in Medicine: Abstracts. Moscow. October 22-25, 1991. P.121.
  4. Builov V.M. Complex application and algorithms of ultrasound scanning and X-ray diagnostics in diseases of the kidneys and ureters: Dis. ... doct. honey. sciences. M., 1995.S. 55.
  5. Modern ultrasound diagnostics of kidney masses / A.V. Zubarev, I. Yu. Nasnikova, V.P. Kozlov et al. // 3rd Congress of the Association of Specialists of Ultrasound Diagnostics in Medicine: Abstracts. Moscow. October 25-28, 1999 p. 117.
  6. US, CT, X-ray diagnosis of Renal Masses / R.K. Zeman, J.J. Croman, A.T. Rosenfield et al. // Radiographics. 1986. Vol.6. P. 351-372.
  7. Thomsen H.S., Pollack H.M. The Genitourinary System // Global TextBook of Radiology. (Ed.) Petterson H. 1995. P. 1144-1145.
  8. Lopatkin N.A., Lyulko A.V. Anomalies genitourinary system... Kiev: I am healthy, 1987. S. 41-45.
  9. Mindel H.J. Pitfalls in Sonography of Renal Masses // Urol. Radiol. 1989. 11.87, No. 4, P. 217-218.
  10. Burykh M.P., Akimov A.B., Stepanov E.P. Echography of the kidney and its pyelocaliceal complex in comparison with the data of anatomical and X-ray studies // Arch. Anat. Gistol. Embriol. 1989. Vol. 97. N9. S.82-87.
  11. Junctional Parenchyma: Revised Definition of Hypertrophic Column of Bertin / H-Ch. Yeh, P.H. Kathleen, R.S. Shapiro et al. // Radiology. 1992. No. 185. P.725-732.
  12. Bobrik I.I., Dugan I.N. Human kidney anatomy with ultrasound // Doctor. a business. 1991. No. 5. S. 73-76.
  13. Khitrova A.N., Mitkov V.V. Kidney Ultrasound: A Clinical Guide to Diagnostic Ultrasound. M .: Vidar, 1996.T. 1.S. 201-204, 209, 212.
  14. Builov V. Junctional parenchyma or hypertrophic column of Bertini: the congruence of their contours and calyceal-pelvic system // Abstracts of ECR \u200b\u200b"99, March 7-12. 1999. Vienna Austria.-Europ. Radiol. Supp. 1. Vol. 9. 1999. S. 447.
  15. Builov V.M., Turzin V.V. Ehotomography and excretory urography in the diagnosis of "bridges" of the renal parenchyma // Vestn. rentgenol.radiol. 1992. No. 5-6. S. 44-51.
  16. Builov V.M., Turzin V.V. Diagnostic value of atypical "bridges" of the parenchyma in renal sonography // 1st Congress of the Association of Specialists of Ultrasound Diagnostics in Medicine: Abstracts. Moscow. October 22-25, 1991. P. 121.
  17. Builov V.M. Questions of terminology and symptom of congruence of the contours of "hypertrophied" Bertini columns or "bridges" of the parenchyma and renal calyx systems // Vestn. rentgenol. and radiol. 2000. N 2.S. 32-35.
  18. Builov V.M. Algorithm for radiological diagnosis of renal pseudotumors // Abstracts of reports. 8th All-Russian. Congress of Radiologists and Radiologists. Chelyabinsk-Moscow. 2001.S. 124-125.

In our observations, it was detected in 0.2% of patients, moreover, in most cases in boys. Echodiagnostics presents certain difficulties that increase when this anomaly is combined with various diseases (hydronephrosis, cysts, polycystic disease, hematomas, paranephritis, tumors, trauma).

An unaffected horseshoe kidney is always located lower than a normal kidney, is large, but never gains the sum of two normal renal sizes, the zone of the parenchyma and the calyx-pelvis system is well delineated. Visualization and differentiation are improved with the application of water loading, which allows for good differentiation of the dilated pelvis. It should be noted that it is very difficult to determine echographically which poles the kidneys are spliced, except in cases when, when viewed through the anterior abdominal wall, it is possible to locate the adrenal glands at opposite poles, and this is possible only with an anomaly of the left kidney.

Galetic kidney

This anomaly is very rare and is formed as a result of the uniform action of forces small intestine during the movement of the kidneys from the small pelvis to the lumbar region. When they are delayed in the pelvis, fusion occurs throughout. The kidney is located low in the pelvis as a flat-oval-elongated formation with clear contours, with a delineation of the parenchyma zone and the calyx-pelvic system without differentiating the fusion site. May be mistaken for a tumor. Echodiagnostics of the biscuit-like kidney is difficult when combined with various diseases. Priority for excretory urography.

Asymmetric forms of fusion include kidneys that have grown together in the form of the Latin letters S, I and L. With this anomaly, the kidneys are fused with opposite poles due to the uneven effect of the forces of the small intestine during their advance from the small pelvis to the lumbar region. Longitudinal axes S and 1-shaped accrete buds are parallel. The S-shaped kidney is located in the pelvis in a horizontal or oblique position, and the I-shaped kidney is located vertically and parallel to the inferior vena cava and the abdominal aorta.

With an L-shaped kidney, the longitudinal axes are perpendicular and are located in the pelvis in a horizontal position. It should be noted that this anomaly is easily confused with a horseshoe kidney. Usually, abnormal kidneys have clear contours with a well-differentiated zone of the parenchyma and often zones of the two calyx-pelvic systems. Sometimes with an S-shaped kidney, it is possible to isolate the isthmus (the place of fusion). Despite the fact that echography reveals the presence of abnormal kidneys, priority in their differential diagnosis for excretory urography.

Quantity anomalies

Double kidney

The most common anomaly in the number of kidneys (approximately 4%) is kidney doubling, which is unilateral and bilateral, complete and incomplete.

Paired kidney

With full doubling, there are two collecting systems - two pelvis, two ureters and two vascular bundles. The echogram clearly shows the pelvis, the beginning of the ureters, sometimes it is possible to isolate the vascular bundles.

A half-doubled kidney differs from a complete one in that it feeds on one vascular bundle. The ureter can be doubled at the top and drain into the bladder with one or two orifices. On the echogram, the doubled kidney looks elongated and is present characteristic feature separation of the zones of the parenchyma and the cup-pelvis system.

Difficulties in echographic differentiation occur with pyelonephritis, hydronephrosis, urolithiasis and with tumors of one of the halves of the double kidney. The complete anatomical picture of a duplicated kidney can only be seen radiographically.

This pathology is extremely rare. Paired buds can be unilateral and bilateral, the same or different in size. According to our data (in the available literature, a description of this pathology was not found), a unilateral paired kidney was detected in 5 women of age and a bilateral one in 2 pregnant women aged 21 and 28 years. In 6 out of 7 cases identified by us, paired kidneys were of the same size, on average 8.2-3.6 cm. For the width of the kidney, we took only 1/2 of the width of the parenchyma zone in the fused part of the kidneys.

A characteristic feature is their longitudinal fusion with lateral surfaces. The echo structure of paired kidneys does not differ from that of a normal kidney, that is, the zones of the parenchyma and the calyx-pelvis system are very clearly distinguished. A special feature is that the width of the parenchyma zone at the site of fusion does not exceed the value in the non-fusion part of the kidneys. According to the echo picture, it can be assumed that fusion occurs at the level of the entire thickness of the parenchyma of both kidneys. The option of complete longitudinal doubling of the kidney is not excluded. The ureters behave in the same way as in a double kidney.

Renal parenchymal anomaly

Renal parenchymal abnormalities include agenesis, aplasia, hypoplastic kidney, accessory (third) kidney, accessory lobule, and cystic parenchymal anomalies - polycystic, multicystic, solitary cyst, multilocular cyst, spongy kidney, megacalycosis, and calyx diverticulum.

Agenesis

Congenital absence of one or both kidneys. With unilateral agenesis on this side, the specificity of the structure of the kidney is not located, however, sometimes it is possible to locate an enlarged adrenal gland. On the opposite side, a hypertrophied kidney, defective in echo construction, is located.

However, it should be remembered that the absence of a kidney location in the anatomical place does not indicate the presence of agenesis. The final diagnosis can be made only after detailed echographic and radiological studies. Bilateral agenesis is very rare and is diagnosed in the fetus in II and III period pregnancy, when all organs are developed. At the same time, a thorough echographic examination does not reveal the echostructure of the kidneys and bladder. The study is carried out with difficulty, since with this anomaly, oligohydramnios is always present. Fruits with this anomaly are born dead.

Aplasia

Deep underdevelopment of the renal parenchyma with frequent cases of absence of the ureter. There can be one- and two-sided.

With unilateral aplasia, the specificity of the structure of the kidney is absent and an oval-elongated formation with indistinct blurred contours is localized, heteroechoic (of different acoustic density), although small cysts and calcifications can be located. It does not appear clinically and is an echographic finding in the study of the kidneys.

Bilateral aplasia is extremely rare. At the same time, the image of the kidneys and urinary bladder cannot be detected in the fetus.

Hypoplastic kidney

Congenital decrease in the size of the kidney. On the echogram, the kidney is reduced in size (on average, it has a length of 5.2 cm, a width of 2.4 cm), the zones of the parenchyma and the pelvis-pelvis system are narrowed, but the specificity of the structure of these zones remains.

In 3 patients, we observed a dwarf kidney 3-2 cm in size. The contours of the kidney are erased, the parenchyma is heterogeneous in echogenicity; there is no division into zones.

It should be remembered that it can be very difficult to distinguish a hypoplastic kidney from a wrinkled kidney, in which the size is also reduced, but the latter has a blurred contour and division into zones; such a kidney is poorly delimited from the surrounding tissues.

Additional (third) kidney

Extremely rare. We have identified 2 cases. The accessory kidney is usually located below the main one and may be slightly smaller than it. In our cases, the main and accessory kidneys were located in the horizontal plane and had the same size, but slightly less than the generally accepted average values \u200b\u200bfor this age (7.1-2.8 cm). The parenchyma and calyx-pelvic system in both kidneys stand out clearly. The ureter of the accessory kidney can drain into the main ureter or independently into the bladder.

An additional lobule of one of the buds may be one (or several) and is located more often at the poles, it is located as a small oval formation with clear contours; the echo structure of the lobules is similar to that of the main kidney tissue. Sometimes additional lobules are easy to mistake for the adrenal gland, although their echo structure is somewhat different, sometimes they can be confused with a bulky formation that grows exophytically.

Anatomical variations of a normally functioning kidney

There are anatomical variations in the structure of the parenchyma and the renal calyx-pelvis system. It should be noted right away that they have no clinical significance, however, some of them may pose diagnostic problems for the researcher.

A parenchymal defect is rare and is located in the form of an echogenic zone of a triangular shape, the base of which is associated with the fibrous capsule, and the apex with the wall of the renal sinus.

Kidney with an oval-convex uneven outer contour

It is quite common. It is characterized by isolated hypertrophy (bulging in the form of a hump) of the parenchyma towards the outer edge of the middle third of the kidney. An inexperienced specialist may mistake it for a tumor with exophytic growth or a carbuncle (with the latter, an acute clinic is present).

Uneven lobular kidney

Usually occurs in children under 2-3 years of age. Rarely does this phase of the embryonic structure persist in adults. It is characterized by a uniform division into 3-4 bulging zones of low echogenicity on the outer surface (parenchyma of the lobules).

Kidney with an isolated zone of parenchymal hypertrophy inward

This anomaly of the parenchyma is quite common, it is characterized by isolated hypertrophy and bulging in the form of a pseudopod between the two pyramids to the calyx-pelvic system, which, in the absence of a clinic, we tend to consider a variant of the individual norm. It can be mistaken for a tumor, and therefore patients with exophytic and endophytic additional growth of the parenchyma should be subjected to invasive research methods.

Polycystic kidney disease

Congenital, always bilateral cystic anomaly parenchyma of the kidneys.

Before the introduction of echography, especially in real time, the diagnosis of polycystic disease presented great difficulties, since the percentage of correct diagnostics by X-ray methods does not exceed 80. In our observations of more than 600 patients, echographic diagnostics was correct in 100% of cases. The polycystic kidney is always enlarged in size, the contours are uneven, oval-convex, the echo structure is not differentiated, only strips of the parenchyma and many rounded anechoic formations (cysts) of different sizes are visible, separated by thin echogenic stripes-septa. Sometimes a polycystic kidney takes the form of a bunch of grapes. But in most cases, several large, up to 5-6 cm in diameter, cysts surrounded by many small ones are located. Sometimes, with dynamic observation of the patient, one can observe the disappearance of large cysts, their ruptures.

The examination is done from the back, but the visualization of the right kidney is better done through the liver. It should be noted that with a significant kidney size and the presence of many cysts, sometimes the liver is only partially visible or not visible at all, and it is possible to erroneously diagnose polycystic liver disease, which is extremely rare.

Multicystic dysplasia

Congenital anomaly, which is often unilateral, since bilateral is not compatible with life. The multicystic kidney is usually large in size, characterized by uneven contours, the parenchyma does not differentiate and is completely replaced by cysts of various sizes, usually 2-3 large ones. For the purpose of differential diagnosis of polycystic and multicystic, use x-ray methods research. Multicystic kidney disease is characterized by high obliteration of the ureter.

Solitary cyst

Distinguish between congenital and acquired renal cysts. Congenital cysts are detected in the fetus in the II and III trimesters of pregnancy or more often in childhood. Acquired cysts are more common after 40 years. There are single and multiple, but no more than 2-3 in one kidney. They are located as rounded formations of different sizes: the minimum is 0.5 cm, the maximum is over 10 cm in diameter. They come from the parenchyma of the kidney and have clear contours, are devoid of echo signals, are located both on the surface and in different parts of the kidney.

A certain difficulty is the clarification of the location of the cyst; first of all, this applies to parapelvic cysts located in the area of \u200b\u200bthe kidney hilum. In some cases, it is difficult to differentiate them from an enlarged pelvis, hydronephrosis, which may have a similar oval shape. In this regard, it should be remembered that in the case of hydronephrosis during echolocation of the kidney, in different scans, an interruption of the contours of the fluid formation is almost always found, that is, the connection with the pelvis and the pelvic-ureteric segment and the calyx, while with parapelvic cysts, interruption of the contours of the fluid formation being located is not observed.

It should be remembered that the image of cysts of the right lobe of the liver or the right half of the abdominal cavity, in particular the mesentery of the intestine in Crohn's or ovarian disease, may be layered on the right kidney. A cyst of the left kidney can be mistaken for a cyst of the lower pole of the spleen, the tail of the pancreas, the left half of the abdominal cavity, the left ovary, or fluid in the stomach with poor evacuation. Such diagnostic errors are unacceptable, because they lead to serious complications, since the access for surgical intervention in these pathologies is different. To avoid mistakes, it is necessary, by changing the position of the body, to carefully differentiate the contours of the kidney in different echographic scans. In doubtful cases, repeated ultrasound examinations and laparoscopy are indicated.

Echography allows for dynamic monitoring of the growth and condition of cysts (suppuration, rupture, resorption). The dynamics of the development of cysts is of great clinical importance, since their growth is associated with atrophy of the renal parenchyma, leading to hemodynamic disturbances and arterial hypertension. Echography helps to clarify the moment of possible surgical intervention or conservative treatment, provides the conditions for conducting targeted diagnostic or therapeutic biopsy.

Dermoid cysts

These are congenital unicameral, rarely multi-chambered rounded formations, outlined by an echogenic capsule. They can be located in various parts of the body, rarely in internal organs and very rarely in the kidneys. They are more common in girls in early childhood, although they can also occur in adults, moreover, be an accidental find. Depending on their content (hair, fat, bone and others) the contents of the formation have different echogenicity - part of the cyst may be high, and part - low (liquid). The wall of the dermoid cyst is thickened, has a high echogenicity, and sometimes it undergoes calcification and is located as a rounded highly echogenic ring, clearly visible on X-ray. It should be noted that sometimes a dermond cyst is echographically difficult to distinguish from a chronic abscess, decay of a cavity and a tumor, hypernephroma and Wilms' tumor. The diagnosis in such cases can be confirmed with a puncture aspiration biopsy or with surgery.

Multilocular cyst

A very rare anomaly (2 cases were identified), characterized by the replacement of a section of the renal parenchyma with a multicameral cyst, which is located as a multicameral anechoic formation, separated by narrow echogenic septa. When a large size is reached, the echo picture is the same as with a multi-chamber echinococcal cyst. Differentiation is very difficult. The only distinguishing feature is that an active echinococcal cyst gives rapid growth compared to a multlocular cyst (in household the patient usually has animals - carriers of echinococcosis).

Spongy kidney

A rare anomaly in which the collecting ducts are dilated.

More often males suffer. In this case, the kidney can be increased in size, a uniform cystic lesion of the pyramids is characteristic, as a rule, bilateral, without the involvement of the cortex in the pathological process. Cysts are usually small in size, 3 to 5 mm in diameter, directed towards the center of the kidney. Although many small cysts can also be found on the surface of the kidney, making it uneven. Many small stones are located in the area of \u200b\u200bthe pyramids. When pyelonephritis is attached, echo diagnosis is difficult.

Megacalycosis (renal calyx dysplasia)

Congenital enlargement of the renal calyces associated with the underdevelopment of the renal pyramids. Usually this anomaly is unilateral, although cases of bilateral lesions have been described. In this case, all cups are affected.

On the echogram, all the cups are significantly expanded, have a rounded shape, the pelvis, as a rule, if pyelonephritis has not joined, is not expanded, the ureter is freely passable for a contrast agent during X-ray examination.

Accumulation of uric acid salts and small stones can be located. Echography of this pathology only allows us to assume the final diagnosis for excretory urography and retrograde pyelography, where the cavity of the cyst, a narrow passage, communicating with the renal calyx, is clearly visible.

Calyx diverticulum

Congenital cystic formation associated with a small renal calyx through a narrow channel.

Megaureter

Congenital unilateral, rarely bilateral segmental expansion along the entire length of the ureter, from 3 mm to 2-3 cm or more, the ureter is located as an uneven width of an anechoic tube over the narrowed distal segment.

The length of the ureter can range from 0.5 to 4-5 cm, more often the left ureter is affected. A megaureter can be primarily obstructive (congenital), secondary obstructive (acquired) due to inflammatory processes, postoperative scars and other causes, and primarily non-obstructive (idiopathic). Megaureter, especially primarily obstructive, always leads to hydronephrosis and hydrocalicosis.

Ureterocele

One of the rare anomalies of the ureter, resulting from the narrowness of its orifice, in which all layers of the intramural ureter expand, bulging in the form of an oval echo-negative formation into the bladder cavity from one or both sides. The ureterocele cavity can contain urine - from a few milliliters to the volume of the bladder.

Ureterocele is difficult to differentiate from a diverticulum or an echinococcal cyst located at the orifice of the ureter.

Early diagnosis of ureterocele is of great importance, as it allows the patient to timely save the patient from possible dilatation of the upper urinary tract and the development of pyelonephritis and secondary cystitis.

Renal vascular anomaly

This area of \u200b\u200bpathology for modern echography, even with the use of Doppler, is little or, more precisely, only partially available. It only allows us to assume the presence of any vascular pathology when comparing structural changes in the renal parenchyma.

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Difficulties and errors of ultrasound and X-ray diagnostics of renal pseudotumors

State Medical Academy,

MySono-U6

Introduction

Kidney tumors account for 2-3% of all malignant neoplasms. Most often they occur as they grow older. Renal cell carcinoma is noted in 80-90% of all kidney tumors. In recent years, the probability of its detection has been increasing, which is associated with both an increase in the number of all malignant tumors and early preclinical diagnosis. To recognize malignant tumors, first of all, it is possible to constantly improve and widely used ultrasound studies of the kidneys.

The first report on the use of ultrasound in the diagnosis of kidney tumors was published in 1963 by J. Donald. Since then, the accuracy of ultrasound diagnostics of kidney tumors has increased from 85-90% to 96-97.3%. When using modern ultrasound scanners operating in tissue and second harmonic modes, as well as color Doppler and energy mapping and dynamic echocontrast angiography, the sensitivity of ultrasound examination (US) is 100% with a specificity of 92 and a predictability of a positive test of 98%, and a negative one - 100% ...

In the literature, there are often publications devoted to errors not only of ultrasound, but also of other methods of radiation diagnostics. There is a point of view that up to 7-9% of all volumetric processes in the kidneys cannot be differentiated prior to operations for cysts, tumors, abscesses, etc. ... The picture of a kidney tumor with ultrasound and other radiation diagnostic methods can simulate many processes. Among them: various kidney anomalies; "Complex" or mixed cysts; acute and chronic nonspecific inflammatory processes (carbuncle, abscess, chronic, including xanthogranulomatous pyelonephritis); specific inflammatory processes (tuberculosis, syphilis, fungal infections of the kidneys); changes in the kidneys with leukemia and lymphomas, including HIV infection; kidney infarction; organized hematomas and other reasons.

In this message, we will only talk about kidney abnormalities, which in the literature are defined by the term pseudotumor. With them, clinical manifestations are almost always absent or determined by concomitant diseases, and the establishment of the correct diagnosis is possible only by methods of radiation diagnostics (Fig. 1).

Figure: 1. Variants of pseudotumors mimicking a tumor.

Materials and methods

For years. observed 177 patients with different structures of the renal parenchyma by the type of renal pseudotumors. All of them repeatedly underwent ultrasound scanning of the kidneys, ultrasound dopplerography (USDG) of the vessels of the kidneys - 78, including using modes of the second and tissue harmonics and energy Doppler - 15, excretory urography (EU) - 54, X-ray computed tomography (RCT) - 36, renal scintigraphy or emission computed tomography (ECT) with 99 m Tc - 21.

Research results

Fetal lobulation of the kidney (see Fig. 1) with multiple bulges along the lateral contour of the kidney was not considered in this report, since it did not necessitate differential diagnosis with a kidney tumor. Among 177 patients with pseudotumors of the kidneys, 22 (12.4%) had a variant of a lobular kidney - a “humped” kidney ”(Fig. 2). In 2 (1.2%) patients, an enlarged “lip” was observed above the hilum of the kidney (Fig. 3a-c). The most common cause of pseudotumor was "hypertrophy" of Bertin's pillars or "bridge" of the renal parenchyma - in 153 (86.4%) patients (Fig. 3d-f). "Bridges" of the parenchyma were noted not only at various doubling of the renal calyx-pelvis systems, but also at their various adhesions and incomplete turns of the kidneys.

The differential diagnosis of pseudotumors and renal tumors required 37 (21%) patients. For this purpose, first of all, repeated "targeted" ultrasound scans were carried out using various additional ultrasound techniques in the conditions of a urological clinic, as well as other methods of radiation diagnostics mentioned above. Only one patient with pseudotumor of the kidney underwent explorative lumbotomy with intraoperative ultrasound-guided biopsy to exclude the diagnosis of a tumor. In the remaining 36 patients, the diagnosis of pseudotumors of the kidneys was confirmed by radiation studies and ultrasound monitoring.

Figure: 2. Echogram (a) and a series of computed tomograms (b) with a "humped" left kidney.

Figure: 3. Echogram, excretory urogram, computed tomogram with contrast enhancement with enlarged "lip" of the kidneys on both sides (a-c) and hypertrophy of the Bertin column (incomplete "jumper" of the parenchyma) in the middle section of the right kidney (d-f), respectively.

Difficulties and errors in radiological diagnosis in pseudotumors of the kidneys usually arose at the first prehospital stages of diagnosis. In 34 (92%) patients, they were associated with both objective difficulties in interpreting unusual echographic data and their incorrect interpretation due to insufficient qualifications of specialists and a relatively low level of diagnostic equipment. In 3 (8%) patients, an erroneous interpretation of X-ray computed tomography data was noted, when a discrepancy was noted with the data of repeated ultrasound scans and X-ray computed tomography in a urological clinic.

Tumors of the kidneys, which had their combinations with a pseudotumor in one kidney, were verified in 2 patients after nephrectomy, and pseudotumors - in one patient with biopsy under ultrasound control during exploratory lumbotomy; for the rest - with ultrasound monitoring over a period of 1 to 10 years.

Discussion

One of the most common reasons for simulating a kidney tumor on ultrasound, the so-called pseudotumor, is most often defined in the literature as Bertin's pillar hypertrophy.

As you know, along the periphery of the ultrasound cut of the kidney, the cortex forms intussusceptions in the form of pillars (columnae Bertin) between the pyramids. Often, Bertin's pillar goes deep enough beyond the inner contour of the parenchyma into the central part of the kidney - into the renal sinus, dividing the kidney more or less completely into two parts. The resulting kind of parenchymal "bridge" is the non-absorbed parenchyma of the pole of one of the kidney lobules, which merge into the kidney of an adult during ontogenesis. The anatomical substrate of "bridges" is the so-called connective tissue defects of the parenchyma or prolapse of the latter into the sinus of the kidney. It includes cortical substance, Bertin's pillars, kidney pyramids.

All elements of the "bridge" are normal parenchymal tissue without signs of hypertrophy or dysplasia. They represent a doubling of the normal renal cortex or its additional layer located lateral to the calyx. The latter is a variant of the anatomical structure of the parenchyma, in particular, the corticomedullary relationship between the parenchyma and the renal sinus. They can be most clearly seen on ultrasound and computed tomographic sections of the kidney.

The absence of parenchymal hypertrophy or dysplasia in the so-called hypertrophy of Bertin's pillars or parenchymal "bridges" was also confirmed by histological studies of biopsy material in one patient with parenchymal "bridges" taken before explorative lumbotomy for a kidney tumor, as well as in two patients with kidney morphology, removed due to a combination in one kidney of a tumor and a pseudotumor ("bridges" of the parenchyma).

In this regard, in our opinion, the most frequently encountered in the literature, the term hypertrophy of Bertin's pillars does not reflect the morphological essence of the substrate. Therefore, we, like a number of authors, believe that the term "jumper" of the parenchyma is more correct. For the first time in the domestic literature on ultrasound diagnostics, we applied it in 1991. It should be noted that the term "jumper" of the parenchyma had other names in the literature (table).

Table Terms used to describe the "bridges" of the renal parenchyma (according to Yeh HC, Halton KP, Shapiro RS et al., 1992)

Wolfman NT et al., 1991

Leekman RN et al., 1983

Long-term experience of excretory urography has shown that the calyx-pelvic systems have an extremely large number of structural options. They are practically individual not only for each person, but also for the left and right kidneys in one subject. With the development and increasingly widespread use of ultrasound and CT, which makes it possible to trace both the internal and external contours of the renal parenchyma, in our opinion, a similar situation is taking shape with respect to the variants of the anatomical structure of the renal parenchyma. Comparison of echo and computed tomographic data with urographic data for various types of renal pseudotumors showed that there is a relationship between the anatomical structure of the parenchyma and the renal calyx systems. It is expressed in the congruence of the medial contour of the parenchyma in the echo or computed tomographic image with the lateral contour of the calyceal-pelvic systems, conventionally performed on excretory urograms or on computed tomograms with contrast enhancement. This symptom can be traced in the usual structure of the parenchyma and calyx-pelvic systems, as well as in the "bridge" of the kidney parenchyma, which is a variant of the anatomical structure. In a kidney tumor, which is an acquired pathological process, the congruence of the contours of the parenchyma and the renal calyx systems is disturbed (Fig. 4).

Figure: 4. Symptom of the congruence of the contours of the parenchyma and the renal calyx-pelvis with an incomplete "bridge" of the parenchyma (explanation in the text).

findings

Thus, the typical echographic pictures of the "bridge" of the kidney parenchyma, the "humpback" kidney and an enlarged "lip" above the hilum of the kidney, which were first detected by ultrasound, do not require further examination.

If a differential diagnosis of pseudotumors and renal tumors is required, which was required in 37 (21%) patients, we propose the following diagnostic algorithm (Fig. 5).

Figure: 5. Algorithm of radiation diagnostics for pseudotumor of the kidney.

  1. Repeated ultrasound by qualified specialists using ultrasound scanners of a higher class using ultrasound, mapping techniques, tissue and second harmonics.
  2. X-ray computed tomography with contrast enhancement or excretory urography with comparison of uro- and echographic data and data of repeated "targeted" ultrasound.
  3. The methods of choice are renal scintigraphy or emission computed tomography with 99 m Tc (false-negative results are possible in small tumors).
  4. With the remaining suspicions of a malignant tumor, a biopsy under ultrasound guidance (only a positive result is of diagnostic value).
  5. If the biopsy result is negative or the patient refuses biopsy and operative revision of the kidney, ultrasound monitoring is performed at a frequency of at least once every 3 months in the first year of observation, and then 1-2 times a year.

Literature

  1. Demidov V.N., Pytel Yu.A., Amosov A.V. // Ultrasound diagnostics in urology. M .: Medicine, 1989. S. 38.
  2. Hutschenreiter G., Weitzel D. Sonographic: einewertwolle erganzung der urologichen Diagnostic // Aktuel. Urol. 1979. Vol. Bd 10 N 2. P. 45-49.
  3. A.K. Nadareishvili Diagnostic capabilities of ultrasound in patients with kidney tumor // 1st Congress of the Association of Specialists of Ultrasound Diagnostics in Medicine: Abstracts. Moscow. October 1991. P.121.
  4. Builov V.M. Complex application and algorithms of ultrasound scanning and X-ray diagnostics in diseases of the kidneys and ureters: Dis. ... doct. honey. sciences. M., 1995.S. 55.
  5. Modern ultrasound diagnostics of kidney masses / A.V. Zubarev, I. Yu. Nasnikova, V.P. Kozlov et al. // 3rd Congress of the Association of Specialists of Ultrasound Diagnostics in Medicine: Abstracts. Moscow, October 1999, p. 117.
  6. US, CT, X-ray diagnosis of Renal Masses / R.K. Zeman, J.J. Croman, A.T. Rosenfield et al. // Radiographics. 1986. Vol.6. P ..
  7. Thomsen H.S., Pollack H.M. The Genitourinary System // Global TextBook of Radiology. (Ed.) Petterson H. 1995. P ..
  8. Lopatkin N.A., Lyulko A.V. Anomalies of the genitourinary system. Kiev: Zdorov'ya, 1987.S. 41-45.
  9. Mindel H.J. Pitfalls in Sonography of Renal Masses // Urol. Radiol. 1989.11.87.N 4. R ..
  10. Burykh M.P., Akimov A.B., Stepanov E.P. Echography of the kidney and its pyelocaliceal complex in comparison with the data of anatomical and X-ray studies // Arch. Anat. Gistol. Embriol. 1989. Vol. 97. N9. S.82-87.
  11. Junctional Parenchyma: Revised Definition of Hypertrophic Column of Bertin / H-Ch. Yeh, P.H. Kathleen, R.S. Shapiro et al. // Radiology. 1992. N 185. R ..
  12. Bobrik I.I., Dugan I.N. Human kidney anatomy with ultrasound // Doctor. a business. 1991. No. 5. S. 73-76.
  13. Khitrova A.N., Mitkov V.V. Kidney Ultrasound: A Clinical Guide to Diagnostic Ultrasound. Moscow: Vidar, 1996.T. 1.S., 209, 212.
  14. Builov V. Junctional parenchyma or hypertrophic column of Bertini: the congruence of their contours and calyceal-pelvic system // Abstracts of ECR'99, March 7-12. 1999. Vienna Austria.-Europ. Radiol. Supp.1. Vol.9. 1999. S. 447.
  15. Builov V.M., Turzin V.V. Ehotomography and excretory urography in the diagnosis of "bridges" of the renal parenchyma // Vestn. rentgenol.radiol. 1992. No. 5-6. S. 44-51.
  16. Builov V.M., Turzin V.V. Diagnostic value of atypical "bridges" of the parenchyma in renal sonography // 1st Congress of the Association of Specialists of Ultrasound Diagnostics in Medicine: Abstracts. Moscow. October 1991. P. 121.
  17. Builov V.M. Questions of terminology and symptom of congruence of the contours of "hypertrophied" Bertini columns or "bridges" of the parenchyma and renal calyx-pelvic systems // Vestn. rentgenol. and radiol. 2000. N 2.S. 32-35.
  18. Builov V.M. Algorithm for radiation diagnosis of renal pseudotumors // Abstracts of reports. 8th All-Russian. Congress of Radiologists and Radiologists. Chelyabinsk-Moscow. 2001.S.
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3.1. Kidney

Modern ultrasound diagnostics of kidney diseases is impossible without a clear understanding of the normal echoanatomy of the kidney, based on a comparison of the echographic picture and the histomorphological substrate.

The kidneys are located retroperitoneally. The right kidney is at the Th-12-L-4 level, the left kidney is located higher - at the Th-11-L3 vertebra level. However, it is rather inconvenient to determine the position of the kidney relative to the vertebrae, therefore, in echographic practice, the hypoechoic acoustic "shadow" from the twelfth rib, the dome of the diaphragm (or the diaphragmatic contour of the liver), the gate of the spleen, and the contralateral kidney are used as a guide to determine the position of the kidney. Normally, the acoustic "shadow" from the twelfth rib crosses (with longitudinal scanning from the back parallel to the long axis of the kidney) the right kidney at the level of the borders of the upper and middle third, and the left kidney at the level of the hilum of the kidney. The upper pole of the right kidney is located at or slightly below the upper diaphragmatic contour of the right lobe of the liver. The superior pole of the left kidney is located at the level of the hilum of the spleen. The distances from the upper pole of the right kidney to the contour of the diaphragm and from the upper pole of the left kidney to the hilum of the spleen depend on the degree of development of the perirenal tissue of the subject.

The size of the kidneys, according to N.S. Ignashin, make up on a longitudinal cut and 3.5 - 4.5 cm, on a transverse cut - 5-6 cm and 3.5 - 4.5 cm.The total parenchyma thickness is 1.2 - 2.0 cm in the middle segment, 2.0 - 2.5 cm in the area of \u200b\u200bthe kidney poles. The normal volume of the kidney is 300 cm3. According to V.N. Demidov, kidney length 7.5 - 12 cm, width 4.5 - 6.5 cm, thickness 3.5 - 5 cm. According to M.P. Burykh and specialists who performed anatomical and echographic correlations, the length of the kidney is 10.41 + 1.3 cm, the width of the kidney is 5.45 ± 1.3 cm, and the thickness is 3.63 ± 0.5 cm.

The cut shape of a normal kidney is bean-shaped or oval in all projections. The contour of the kidney is usually even, and in the presence of preserved fetal lobulation of the kidney, it is wavy (this is a variant of the normal structure of the kidney). Quite often, a local bulging of the contour in the area of \u200b\u200bthe lateral edge of the kidney (in this case, the so-called "humped" kidney is determined) or in the area of \u200b\u200bthe edge of the renal sinus, which simulates a tumor of the kidney, is normally determined. These conditions are described as pseudotumors and are also variants of the normal structure of the kidney. One of the hallmarks of pseudotumor "bulging" of the parenchyma with preserved fetal lobulation of the kidney, in contrast to the tumor, is the preservation of the parallelism of the outer and inner contours of the parenchyma, the preservation of the normal echostructure of the parenchyma.

In fig. 18 shows an echogram of a normal adult kidney.

The echographic characteristics of the renal capsule and parenchyma of the normal kidney are generally accepted. On the periphery of the ultrasound cut of the kidney, a fibrous capsule is seen in the form of a hyperechoic smooth, continuous structure 2 - 3 mm thick, then the parenchyma layer is determined. The hilum of the kidney is located echographically in the form of a "rupture" in the medial contour of the renal parenchyma, while scanning from the side of the anterior abdominal wall at the top of the scan visualizes an anechoic tubular structure located in front - the renal vein, located behind the hypoechoic renal artery. The parenchyma is heterogeneous and consists of two layers: the cortex and the medullary (or the substance of the kidney pyramids). The morphological substrate of the renal cortex (kidney cortex) is mainly the glomerular apparatus, convoluted tubules, interstitial tissue containing blood, lymphatic vessels, and nerves. Medullary substance contains Henle loops, collecting ducts, Bellini ducts, interstitial tissue. The cortical substance of the kidney is located on the periphery of the ultrasound cut of the kidney with a thickness of 5 - 7 mm, and also forms invaginations in the form of columns (columnae Bertini) between the pyramids. In fig. 19, 20 show a schematic representation of the layers of the parenchyma and a technique for measuring the thickness of the elements of the parenchyma. Often, Bertin's column extends far enough beyond the inner contour of the parenchyma into the central part of the kidney - into the renal sinus, dividing the kidney more or less completely into two parts. The resulting kind of parenchymal "bridge", the so-called hypertrophied Bertin's column, is the unabsorbed parenchyma of the pole of one of the kidney lobules, which merge during ontogenesis to form an adult kidney. This bridge consists of cortex, Bertin's columns, and kidney pyramids. All bridge elements are normal parenchymal tissue with no signs of hypertrophy or dysplasia.

Therefore, the name "hypertrophied Bertin's column" existing in the literature does not reflect the morphological essence of the substrate, and, probably, the definition of Zh.K. Ena et al, who called this formation a parenchymal jumper. The echogenicity of the renal cortex is usually slightly lower or comparable to the echogenicity of the parenchyma of the normal liver. The pyramids of the kidney are defined in the form of triangular structures with reduced echogenicity compared to the cortex. In this case, the apex of the pyramid (papilla of the pyramid) is facing the renal sinus - in the central part of the cut of the kidney, and the base of the pyramid is adjacent to the cortex of the parenchyma located along the periphery of the cut (see Fig. 19). The pyramids of the kidney are 8 - 12 mm thick (the thickness of the pyramids is defined as the height of the triangular structure, the apex of which is facing the renal sinus), although the normal size of the pyramids largely depends on the level of urine output. Normally, echographic differentiation of the cortex and pyramids is expressed: the echogenicity of the cortical substance is much higher than the echogenicity of the kidney pyramids. Often, this difference in echogenicity is the reason for a false-positive diagnosis of hydrocalicosis, when very dark, low echogenicity of the pyramids are mistaken by novice ultrasound diagnostics doctors for dilated cups. Modern histomorphological studies of the renal parenchyma and their comparison with the echographic picture suggest that pronounced echographic corticomedullary differentiation is due to a significant difference in the number of fatty vacuoles in the epithelium of tubular structures of the cortex and pyramids. However, it is impossible to explain the different echogenicity of the cortex and pyramids only by the different content of fatty vacuoles in the epithelium of tubular structures, since it is known that the echogenicity of the pyramids of the kidney with a high level of urine output is much lower than the echogenicity of the pyramids of the same kidney under normal conditions, the number of fatty vacuoles, depending on the level of urine output does not change. Also, the low echogenicity of the pyramids cannot be explained by the presence of fluid in the tubular structures, since the resolution of the ultrasound apparatus under any conditions does not allow differentiating the lumen of the tubule and the fluid in it. It can be assumed that the low echogenicity of the medullary substance is associated with:

1) with a high content of glycosaminoglycans in the interstitial tissue, where most of the functional processes occur that provide ion exchange, water and electrolyte reabsorption, urine transport; glycosaminoglycans are able to "bind" liquid, according to the authors of the hypothesis, "swelling and swelling very quickly";

2) the presence of smooth muscle fibers in the interstitial tissue surrounding the excretory ducts of the renal papilla.

In children, the echogenicity of the cortical substance is much higher than in adults, which is explained by the more compact arrangement of the glomeruli and less interstitial tissue. Pyramids occupy a larger area than adults. Morphometric studies have shown that in newborns, the cortex and pyramids occupy about 90% of the volume of the kidney, in adults, the percentage decreases to 82%.

In the center of the echographic section of the kidney, a hyperechoic complex of an oval or round shape (depending on the scanning plane) is determined, the renal sinus, the size and echogenicity of which are differentiated to a large extent depending on the age of the subject and his dietary habits.

If the echographic characteristics and interpretation of the image of the normal parenchyma are generally accepted in medical practice and in scientific developments, then the interpretation of the central echo complex differs significantly among different authors. In practical work, as well as in scientific articles Some authors make a semantic identification of the central echo complex and the renal calyx-pelvis system. However, carrying out modern histomorphological and echographic correlations of a normal kidney has convincingly proved that the central echo complex is not a summary display of the calyx-pelvic system, but of the entire set of elements of the renal sinus. By comparing the anatomical and echographic data, it was found that it is the renal sinus, and not the calyceal-pelvic system, as previously thought, is the morphological substrate of the central echo complex.

Very little has been written about the renal sinus as an anatomical whole, although there is abundant medical research data describing various pathologies of the renal sinus. When imaged, many states give a similar picture. Misdiagnosis may occur when a diagnosis is attempted without considering the various possibilities.

The renal sinus is a specific anatomical structure that surrounds and includes the collecting system of the kidneys. It is bordered on the lateral side by the renal pyramids and cortical columns. The medial-renal sinus communicates with the panephral space through the renal hilum. The elements of the renal sinus are lymphatic, nervous, renovascular structures surrounded by adipose and fibrous tissue. The decrease in the percentage of the parenchyma in the volume of the kidney in an adult in comparison with a newborn occurs precisely due to an increase in the volume of the renal sinus, which occurs as a result of "age-related" proliferation of the renal sinus tissue. The adipose tissue of the renal sinus is practically absent in the newborn, which is echographically manifested by the absence of reflected echoes from the renal sinus or in the minimally expressed central echo complex in the form of a delicate, branched, weakly echogenic structure. In contrast to the kidney of an adult, the medullary layer is more pronounced, the central echo complex is represented by a smaller branchy structure in terms of area and echogenicity. By the age of 10, the renal sinus is almost completely formed. Similar data were obtained in MR studies of the kidneys of healthy children (an intense signal on T 1-weighted images, corresponding to sinus tissue, appears in the age group of children over 10 years old.

So, the echogenicity of the central complex is primarily due to the presence and amount of adipose tissue of the renal sinus. However, in addition to high-intensity reflections, the central echo complex contains small zones of low echogenicity and anechoic zones. For a long time it was believed that these zones are reflections of the elements of the pelvis-calyx system. The data on the normal echographic sizes of the calyx-pelvic system in adult subjects are extremely contradictory and scarce. So, in 1982, A. Deina reports on the "syndrome of echographic invisibility of the calyx-pelvis system". I.S. Amis calls dilatation of the calyx-pelvic system any "splitting" of the calyx-pelvic system by an echo-negative stripe. K.K. Hayden, L.I. Svishuk is normally allowed to have only a thin layer of fluid in the calyx-pelvis system. In this case, the presence of expansion of the pelvis and calyx structures and their fusion in the form of a "tree" is, according to these authors, a sign of hydronephrosis. T.S. Khikhashi, comparing the data of echography, Doppler ultrasound and excretory urography, came to the conclusion that the classification of hydronephrosis by P.Sh. Illenboden, describing echographically detected hydronephrosis in degrees as a splitting of the central echo complex in the form of: a) a branchy tree structure, b) a lily structure, c) a clover structure, d) a rosebud, leads to a false-positive diagnosis of hydronephrosis. According to these authors, the splitting of the central echo complex in the form of a tree corresponds to normal vascular structures, an echo-negative structure in the form of a lily corresponds to a normal pelvis or, possibly, an obstructive process, a structure in the form of a rosebud is the initial form of hydronephrosis, in the form of a clover is pronounced hydronephrosis. At the same time, false positive diagnosis of hydronephrosis occurred in 11%, false negative - in 22% of cases. Quantitative estimates of the size of the normal calyx-pelvis system are not given in the work of these authors. Although I. Khash tried to use the size of the pelvis as an index that determines the degree of hydronephrosis, data defining the anteroposterior size of the pelvis as a differential diagnostic criterion for norm and pathology were not presented. F.S. Will considers an anteroposterior pelvis of 30 mm to be the norm, which from our point of view is completely unacceptable. V.N. Demidov, Yu.A. Pytel, A.V. Amosov determine the normal anteroposterior size of the pelvis in 1 - 2.5 cm. Imnaishvili believes that visualization of the cups in the form of anechoic, rounded formations up to 5 mm in diameter is normally acceptable. The pelvis can be visualized as two hyperechoic linear structures going towards the hilum of the kidney.

The data of T.Ch. Tce and coauthors. The study of these authors was undertaken in order to establish the echographic dimensions of the normal renal pelvis in children and to determine the correlation between its size and the presence of one or another renal pathology, as well as the dependence of the pelvis size on age. It was found that the upper limit of the norm of the anteroposterior size in children is 10 mm, and only 1.7% of the normal renal pelvis exceeded 10 mm. Correlation analysis did not reveal statistically significant differences in the size of the renal pelvis in different age groups, although the mean values \u200b\u200bof the size in the normal group and in the pathology group were statistically different (р

The pyramids of the kidneys are defined zones through which urine enters the calyx-pelvic system after filtration of fluid from the bloodstream through the tubular systems. Already from the chls, urine moves along the ureter and enters the bladder. Violations of the pyramids can be observed in one or both kidneys, which leads to dysfunction of the organ and requires mandatory treatment. Identification of pathological changes is carried out by means of ultrasound and only after examination and diagnosis, the doctor prescribes the necessary therapy.

What does hyperechogenicity of pyramids mean?

Pyramids of the kidneys are defined areas through which urine enters the calyx-pelvic system after filtration of fluid from the bloodstream

The normal healthy state of the kidneys means the correct shape, uniformity of the structure, symmetrical arrangement, and at the same time, the ultrasound waves on the echogram - a study carried out when a disease is suspected, are not reflected. Pathologies change the structure, appearance of the kidneys and have special characteristics that indicate the severity of the disease and the state of the inclusions.


For example, organs can be asymmetrically enlarged / reduced, have internal degenerative changes parenchymal tissue - all leads to poor penetration of the ultrasound wave. In addition, echogenicity is impaired due to the presence of stones and sand in the kidney.

Important! Echogenicity is the ability of a wave to reflect sound from a solid or liquid substance. All organs are echogenic, which allows an ultrasound scan. Hyperechoicity is a reflection of increased strength, revealing inclusions in organs. Based on the readings of the monitor, the specialist detects the presence of an acoustic shadow, which is the determining factor in the density of inclusion. Thus, if the kidneys and pyramids are healthy, the study will not show any wave deviations.

Symptoms of hyperechogenicity

Syndrome of hyperechoic kidney pyramids causes pain in the lower back of a cutting, stabbing nature

Syndrome of hyperechoic renal pyramids has a number of symptoms:

  • Body temperature changes;
  • Pain in the lower back of a cutting, stabbing character;
  • Change in color, odor of urine, sometimes blood droplets are observed;
  • Stool disorder;
  • Nausea, vomiting.

The syndrome and symptoms indicate an overt kidney disease that needs to be treated. Isolation of pyramids can be caused by various organ diseases: nephritis, nephrosis, neoplasms and tumors. Additional diagnostics, doctor's examination and laboratory tests are required to establish the underlying disease. After that, the specialist prescribes measures of therapeutic treatment.

Types of hyperechoic inclusions

All formations are divided into three types, based on what picture is visible on ultrasound

All formations are divided into three types, based on what picture is visible on ultrasound:

  • A large inclusion with an acoustic shadow most often indicates the presence of stones, focal inflammation, disorders of the lymphatic system;
  • A large formation without a shadow can be triggered by cysts, fatty layers in the sinuses of the kidneys, tumors of a different nature or small stones;
  • Small inclusions without a shadow are microcalcivicates, psammary bodies.
  • Possible diseases depending on the size of the inclusions:

  • Urolithiasis or inflammation - manifested by large echogenic inclusions.
  • Single inclusions without a shadow signal:
    • hematomas;
    • sclerotic vascular changes;
    • sand and small-sized stones;
    • scarring of organ tissues, for example, parenchymal tissues, where scarring has occurred due to untreated diseases;
    • fatty seals in the sinuses of the kidneys;
    • cystosis, tumors, neoplasms.

    Important! If the monitor of the device shows obvious sparkles without a shadow, then in the kidneys there may be an accumulation of compounds (psammomny) of a protein-fatty nature, framed by calcium salts or calcifications. It is not recommended to skip this symptom, as this may be the beginning of the development of malignant tumors. In particular, oncological formations include calcifications in 30%, psammonic bodies in 50%.

    The inclusion of an echo complex of the kidneys on ultrasound is a study that allows to identify abnormal development all parts of the organ, the dynamics of diseases and parenchymal changes. Depending on the echogenic parameters, the characteristics of the disease are determined, therapeutic and other treatment is selected.

    As for the symptoms, even knowing what it is about the pyramids in the kidneys, what pathologies are indicated by changes in structure and echogenicity, the implicitness of the symptoms of the disease often does not cause concern. Patients resign themselves to pain and delay the visit to the doctor. It is categorically not recommended to do this: if the disease has touched the pyramids, it means that the pathological changes have gone far enough and can turn into not only purulent inflammatory processes, but also chronic diseases, for the treatment of which it will take a lot of time and money.

    Source

    03-med.info

    The structure and purpose of the parenchyma

    Under the capsule are several layers of dense substance of the parenchyma, differing both in their color and consistency - in accordance with the presence of structures in them that allow performing the tasks facing the organ.

    In addition to its most famous purpose - to be part of the excretory (excretory) system, the kidney also performs the functions of an organ:

    • endocrine (intrasecretory);
    • osmo- and ion-regulating;
    • participating in the body both in the general metabolism (metabolism) and in blood formation - in particular.

    This means that the kidney not only filters the blood, but also regulates its salt composition, maintains the water content that is optimal for the body's needs, affects the level of blood pressure, and, in addition, produces erythropoietin (a biologically active substance that regulates the rate of erythrocyte formation) ...

    Cortical and medullary layers

    According to the generally accepted position, the two layers of the kidney are usually called:

    • cortical;
    • brain.

    The layer that lies directly under the dense elastic capsule, the outermost in relation to the center of the organ, the densest and most light-colored, is called cortical, while the one located under it, darker and close to the center, is the cerebral layer.

    A fresh longitudinal section reveals even to the naked eye the heterogeneity of the structure of the renal tissues: it shows radial striation - structures of the medulla, which are pressed into the cortical substance with semicircular tongues, as well as red dots of the renal corpuscles-nephrons.

    With a purely external monolithicity, the kidney is characterized by lobulation due to the existence of pyramids, delimited from each other by natural structures - renal columns formed by the cortex dividing the brain into lobes.

    Glomeruli and urine formation

    To be able to purify (filter) blood in the kidney, there are zones of direct natural contact of vascular formations with tubular (hollow) structures, the structure of which makes it possible to use the laws of osmosis and hydrodynamic (arising from fluid flow) pressure. These are nephrons, the arterial system of which forms several capillary networks.



    The first is a capillary glomerulus completely immersed in a cup-shaped depression in the center of the flask-shaped expanded primary element of the nephron - the Shumlyansky-Bowman capsule.

    The outer surface of the capillaries, consisting of a single layer of endothelial cells, is almost entirely covered with cytopodia intimately tightly adjacent to it. These are numerous pedunculate processes, originating from the centrally passing cytotrabekula beam, which in turn is a process of a podocyte cell.

    They arise as a result of the entry of the "legs" of some podocytes into the intervals between the same processes of other, neighboring cells with the formation of a structure resembling a "lightning" lock.

    The narrowness of the filtration slits (or slit diaphragms), caused by the degree of contraction of the "legs" of podocytes, serves as a purely mechanical obstacle for large molecules, preventing them from leaving the capillary bed.

    The second miraculous mechanism that ensures the fineness of filtration is the presence on the surface of slit diaphragms of proteins that have an electric charge that is the same as the charge of molecules approaching them in the filtered blood. This electrical “curtain” also prevents unwanted components from entering the primary urine.


    The mechanism of formation of secondary urine in other parts of the renal tubule is due to the presence of osmotic pressure directed from the capillaries into the lumen of the tubule, braided by these capillaries until their walls "stick" to each other.

    Parenchyma thickness at different ages

    Due to the offensive age changes tissue arthrophy occurs with thinning of both the cortical and medullary layers. If at a young age the parenchyma thickness is from 1.5 to 2.5 cm, then upon reaching 60 or more years it becomes thinner to 1.1 cm, leading to a decrease in the size of the kidney (its shrinkage, usually bilateral).

    Atrophic processes in the kidneys are associated both with the maintenance of a certain lifestyle and with the progression of diseases acquired during life.

    The conditions causing a decrease in the volume and mass of the renal tissue are caused by both general vascular diseases of the sclerosing type and the loss of the renal structures' ability to perform their functions due to:

    • voluntary chronic intoxication;
    • sedentary lifestyle;
    • the nature of the activity associated with stress and occupational hazards;
    • living in a certain climate.

    Column Bertini

    Also referred to as bertinium columns, or renal pillars, or Bertin's pillars, these beam-like bands of connective tissue, which run between the pyramids of the kidney from the cortex to the medulla, divide the organ into lobes in the most natural way.



    Because inside each of them there are blood vessels that provide metabolism in the organ - the renal artery and vein, at this level of their branching they are called interlobar (and at the next - lobular).

    Thus, the presence of Bertin's pillars, which differ in a longitudinal section from the pyramids in a completely different structure (with the presence of sections of tubules extending in different directions), allows communication between all zones and formations of the renal parenchyma.

    Despite the possibility of the existence of a fully formed pyramid inside the especially powerful Bertin's column, the same intensity of the vascular pattern in it and in the cortical layer of the parenchyma indicates their common origin and purpose.

    Parenchymal jumper

    The kidney is an organ that can take any shape: from the classic bean-shaped to horseshoe-shaped or even more unusual.

    Sometimes ultrasound of an organ reveals the presence of a parenchymal bridge in it - a connective tissue retraction, which, starting on its dorsal (posterior) surface, reaches the level of the median renal complex, as if dividing the kidney across into two more or less equal “semi-fasolines”. This phenomenon is explained by too strong wedging of Bertin's pillars into the kidney cavity.

    With all the seeming unnaturalness of such an organ's appearance with the absence of its vascular and filtering structures, this structure is considered a variant of the norm (pseudopathology) and is not an indication for surgical treatment, just like the presence of a parenchymal constriction dividing the renal sinus into two seemingly separate parts, but without a complete doubling of the pelvis.

    The ability to regenerate

    Regeneration of the renal parenchyma is not only possible, but also safely carried out by the organ under certain conditions, which has been proven by many years of observation of patients who have undergone glomerulonephritis - an infectious-allergic-toxic kidney disease with massive damage to the renal corpuscles (nephrons).

    Studies have shown that the restoration of organ function is not due to the creation of new ones, but by the mobilization of existing nephrons, which were previously in a conserved state. Their blood supply remained sufficient solely to maintain their minimum vital functions.

    But the activation of neurohumoral regulation after the acute inflammatory process subsided led to the restoration of microcirculation in the zones where the renal tissue was not subjected to diffuse sclerosis.

    These observations allow us to conclude that the key moment for the possibility of regeneration of the renal parenchyma is the possibility of restoring blood supply in areas where it has significantly decreased for any reason.

    Diffuse changes and echogenicity

    In addition to glomerulonephritis, there are other diseases that can lead to the appearance of focal atrophy of the renal tissue, which has varying degrees of extent, called the medical term: diffuse changes in the structure of the kidneys.

    These are all diseases and conditions leading to vascular hardening.

    The list can begin with infectious processes in the body (flu, streptococcal infection) and chronic (habitual household) intoxication: alcohol intake, tobacco smoking.

    It ends with industrial and service-related hazards (in the form of work in an electrochemical, galvanic workshop, activities with regular contact with highly toxic compounds of lead, mercury, as well as associated with exposure to high-frequency electromagnetic and ionizing radiation).

    The concept of echogenicity implies the heterogeneity of the structure of an organ with varying degrees of permeability of its individual zones for ultrasound examination (ultrasound).

    Just as the density of various tissues is different for X-ray "transmission", both hollow formations and areas with a high tissue density can be found on the path of the ultrasound beam, depending on which the ultrasound picture will be very diverse, giving an idea of \u200b\u200bthe internal structure organ.

    As a result, the ultrasound method is a truly unique and valuable diagnostic study that cannot be replaced by any other, which allows you to give a complete picture of the structure and function of the kidneys without resorting to autopsy or other traumatic actions in relation to the patient.

    Also, the outstanding ability to recover in case of damage, it is possible to largely regulate the life of the organ (both by saving it by the owner of the kidneys, and by providing medical care in cases requiring intervention).

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    Syndrome of hyperechoic renal pyramids

    If it is long, then chronic renal failure, if acute, then acute renal failure. Poisoning can be the cause of both. The kidneys play an important role in human body, and depends on their normal functionality general state health. Therefore, when the first signs of malaise appear, it is recommended to immediately provide the necessary assistance to the kidneys.

    Common Symptoms That Cause Kidney Problems

    When these symptoms appear, it is important to immediately contact your doctor who will prescribe an immediate examination and the necessary tests. Also, these symptoms may indicate that the patient has one kidney larger than the other, therefore it is necessary to undergo additional examination, including renal clearance. In the event that, after hypothermia, the kidneys began to hurt in a person, only one conclusion can be drawn - this means that the development of the inflammatory process began earlier.

    Symptoms associated with kidney disease

    A person can get closed kidney injuries in car accidents, when falling from a height, and even during sports. Each of these types of diseases has its own dangers, so in no case should you experiment on yourself and self-medicate. Often, patients who actually have a kidney carbuncle end up in the hospital under completely different diagnoses.

    Types of hyperechoic inclusions and diagnostics

    With this disease, pus is also released, therefore it is very dangerous and requires immediate hospitalization of the patient in a medical institution. It has been proven that dietary nutrition has a very beneficial effect on many kidney diseases and allows them to work sparingly.

    The kidneys are a paired organ and in the human body perform several functions simultaneously. Therefore, during a diagnostic ultrasound examination, a mandatory examination of both kidneys is carried out. The dysfunction can start on one side and affect the other. Hyperechoic inclusions in the kidneys can be observed in one or two. The location of the inclusions is very diverse and depends on the predisposing unfavorable factors.

    Kidney Disease Website

    Pathological processes of various etiologies change the structure and appearance of the kidneys, depending on the severity of the disease and the condition of the inclusions. Hyperechogenicity means super strong reflection, indicating the presence of any inclusions in the kidneys. There are several types of echogenic inclusions, which determine the pathological state of the kidneys. Hyperechoic inclusions are divided into two large groups: stones (sand) and neoplasms.

    Large inclusions in the kidneys. This can also be confirmed by the presence of calcifications and psammotic bodies in the tumor, as well as sclerosed areas. The examination may reveal several different types echogenic inclusions. Disruption of kidney function is always accompanied by weakness and fatigue. This state is inherent acute development diseases or a phase of exacerbation of chronic pathological processes in the kidneys.

    Therapeutic measures and prevention

    It is necessary to assess the state of the renal parenchyma against the background of prominent pyramids. Depending on the neglect of the condition and the type of pathological process, treatment can be therapeutic or surgical.

    Pyelonephritis is an inflammatory process that occurs only in the calyx-pelvic system of the kidney, accompanied by pronounced laboratory changes. Figure: 1 Visualization of the right kidney. The sensor is located in the right posterior axillary line.

    Necessary treatment

    As with a complete examination of any other organs, it is necessary to examine the kidney in a second projection to examine its cross-section. The sensor can be installed directly under the costal arch or in the area of \u200b\u200bthe last intercostal space.

    Clinical manifestations

    The left kidney is also located in a kind of triangle, the sides of which are the spine, muscles and spleen. The echographic characteristics of the renal capsule and parenchyma of the normal kidney are generally accepted.

    Partial or complete rupture of the collecting system image at the same site indicates a doubling of the kidney with separate ureters and blood supply for each half.

    Kidney dystopia is an abnormality in the development of the kidney, in which the kidney does not rise to its normal level during embryogenesis. In this case, variants of heterolateral dystopia with and without renal fusion are possible. With echographic detection of an abnormally located kidney, difficulties in differential diagnosis of nephroptosis and dystopia usually arise. It should be remembered that the kidney with nephroptosis has a normal length of the ureter and a vascular pedicle located at the usual level (level L1-L2 of the lumbar vertebrae).

    As for the increase in the echogenicity of the parenchyma and the protruding pyramids, here the reasons for this condition may be different. In newborns, the structure and condition of the pyramids themselves and the fluids released through them are assessed. The base of the triangle is the border between the cortex and the pyramid along the periphery of the pyramid cut. The syndrome itself is not life-threatening and is a symptom of the disease, which is established after a complete comprehensive examination.

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    Concepts - hyperechoicity and acoustic shadow?

    Echogenicity is the ability of bodies of liquid and solid consistency to beat off ultrasonic waves. All organs located inside a person are echogenic, this is what allows ultrasound examination. Ultrasound helps to study the activity of the kidneys, determine their integrity and confirm or exclude the presence of malignant or benign neoplasms. Have healthy person a rounded organ with a symmetrical location and inability to reflect sound waves. In cases of pathologies, the size of the kidneys changes, the location becomes asymmetrical and inclusions appear that can beat off sound waves.

    On ultrasound, hyperechoic inclusions look like white spots.

    Hyper refers to the increased ability of echogenic tissues to reflect ultrasonic waves. During an ultrasound scan, a specialist sees white spots on the screen and determines whether they have an acoustic shadow, more precisely, a cluster of ultrasonic waves that did not pass through it. Waves have a much higher density than air, therefore they cannot pass exclusively through a dense object. Hyperechogenicity is not a separate disease, but a symptom indicating the appearance of various kinds of pathologies inside the kidneys.

    Anatomy of the kidneys and adjacent organs of CT in the frontal plane: 1 - right point (Th 12 - L 4) 2 - liver 3 - spleen 4 - left kidney (Th 11 - L 3) 5 - spine The arrow indicates the location of the right adrenal gland.

    Topographic anatomy The kidneys are located in the lumbar region on either side of the spine, retroperitoneally, lie on the inner surface of the posterior abdominal wall in the renal bed formed by the sheets of the renal fascia and filled with adipose tissue.

    TOPOGRAPHIC AHATOMY The upper right kidney is in contact with the adrenal gland (I) and the liver (II). At the lower pole, the right bend of the colon is adjacent to the kidney (III). In the area of \u200b\u200bthe hilum, the kidney is covered by the duodenum (IV). The left kidney is in contact with the adrenal gland (V), stomach (VI), spleen (VII), pancreas (VIII), left bend of the colon (IX) and loops of the small intestine (X). The diaphragm and lumbar muscles are adjacent to the posterior surface of the kidneys.

    Indications for ultrasound examination of the kidneys: 1 Anamnestic indications of the presence of diseases of the genitourinary system 2 The presence of complaints characteristic of diseases of the genitourinary system 3 The presence of changes in clinical and laboratory parameters characteristic of diseases of the genitourinary system 4 As a screening of risk groups for the development of diseases of the genitourinary system 5 Persons with high blood pressure indicators

    Preparation for ultrasound examination of the kidneys - Compliance with the diet for 2-3 days before the study: exclusion from the diet of vegetables, fruits, black bread, dairy products, vegetable juices. - With severe bloating, the use of drugs that reduce gas production: activated carbon, espumisan. - Enemas are contraindicated.

    Scan planes Renal examination - polypositional !! The right kidney is easily located transabdominally from the right hypochondrium through the liver, longitudinal, transverse and oblique scans are used, the left kidney from the left intercostal space is located only in children and asthenics. Both kidneys can be located in the patient's lateral position: the sensor is installed parallel or perpendicular to the direction of the oblique abdominal muscles. Translumbar longitudinal and transverse scanning is also used. When the dome of the diaphragm is high, it is possible to visualize the kidneys through the intercostal spaces. With severe flatulence, the kidneys are better visualized in a sitting position with the hands behind the head.

    Evaluation of the ultrasound picture 1. Location of the kidneys 2. The shape of the kidneys 3. The contours of the kidneys 4. The size of the kidneys 5. The echogenicity of the kidneys 6. The state of the pyelocaliceal system 7. The state of the perirenal tissue 8. Additional techniques: CDC and DG

    The kidney has a bean-shaped shape, its lateral edge is convex, the medial edge is concave. In the middle part of the medial edge there is a renal gate, which includes the neurovascular bundle and pelvis. In the fatty tissue of the gate, the lymph nodes are located.

    The renal hilum passes into the renal sinus. The renal sinus contains the elements of the collecting system of the kidneys - the calyx, the pelvis, as well as the blood and lymph vessels, nerves and adipose tissue. All these elements are determined by ultrasonography as a central echo complex, this is the most echogenic part of the kidney.

    The parenchyma of the kidney is a less echogenic part of it, has a thickness from the top of the pyramid to the capsule of the kidney 1, 2 - 1, 8 cm and consists of two sections - cortical and medullary. Medullary layer - divided into 10-18 pyramids, between which there are 10-15 renal pillars (columnae renales, Bertini), which are spurs of the cortex within the medulla.

    In each pyramid, a base is distinguished, facing the surface of the kidney, and the apex, directed to the renal sinus. The tops of the pyramids, sometimes combining 2 or 3, form a papilla protruding into the lumen of the small calyx. The small calyxes form a large calyx, the large calyxes join to form the pelvis.

    Kidney shape Normally formed kidneys are bean-shaped and have clear, even contours; the gate of the kidneys is located medially. Variants of the norm are the so-called "lobed" and "humped" kidneys. "Fetal lobulation" occurs in children and is manifested by the presence of furrows on the surface of the right and left kidneys. Humpbacked kidney is caused by compression of the left kidney by the spleen during intrauterine development.

    Length is the largest measurement obtained with a longitudinal scan of the kidney. Width - transverse, thickness - anteroposterior size of the kidney during its transverse scanning at the level of the hilum. The normal sizes of the kidneys of an adult are as follows: length 9, 0 - 12, 0 cm, width 4, 5 - 6, 0 cm and thickness 3, 5 - 5, 5 cm.The width of a normal kidney is half its length, and the thickness is normally less than the width ... The volume of the kidney is determined by the formula of a truncated ellipse: Volume of the kidney \u003d Length (cm) x Width (cm) x Thickness (cm) x 0.52 The volumes of the right and left kidneys are normally approximately equal. The volume of the kidneys in newborns is approximately 20 cm 3, at the age of 1 year - 30 cm 3, by 18 years - 155 cm 3, in an adult - 250-300 cm 3.

    Children: Length: newborn - 4, 5 cm, 1 year - 6, 2 cm, each subsequent year + 0.3 cm [Pykov M. I., 1998] Newborns: length 4 - 4, 5 cm, width 2, 5 - 2, 7 cm, thickness 2 - 2, 3 cm, 1 year - length 7 cm, width 3, 7 cm, thickness 2, 6 cm [Dvoryakovsky I. V., 1994] Length: newborn - 4 - 5 cm, 1 year - 5, 5 - 6, 5 cm, 5 years - 7, 5 - 8, 5, 10 years - 8, 5 - 10 cm

    Adults: Length 10-12.5 cm, width 5-6 cm, thickness 4-5 cm [Glazun L.O., 2005] Length 10-12 cm, width 5-6 cm, thickness 4-5 cm [Zubarev A V., Gazhonova V. Ye., 2002] Length 10-12 cm, width 5-6 cm, Thickness 3.5-4.5 cm [Ignashin N.S., 1997] Length 10-11 cm, width 5 cm, thickness 3 cm

    Echogenicity of the kidneys The kidney cortex normally has echogenicity slightly below the parenchyma of the liver or spleen, and the renal pyramids are hypoechoic relative to the cortex. The difference between the echogenicity of the cortex and the renal pyramids defines the concept of "cortico-medullary contrast". It is also necessary to evaluate the difference in echogenicity of the parenchyma and renal sinus.

    Convenient in clinical application the classification of cortical echogenicity was proposed by H. Hri sak et al (1982). It is based on a visual comparison of the echogenicity of the cortex of the right kidney during its longitudinal scanning with the echogenicity of a healthy liver and renal sinus and assumes the following gradation:

    Grade 0: The echogenicity of the renal cortex is lower than the echogenicity of the liver (N). Grade 1: The echogenicity of the renal cortex is equal to the echogenicity of the liver (N). Grade 2: The echogenicity of the renal cortex is higher than the echogenicity of the liver, but below the echogenicity of the central echocomplex. Grade 3: The echogenicity of the renal cortex is equal to the echogenicity of the central echo complex.

    The state of the renal pelvic system The renal sinus is an anatomical structure that surrounds and includes the collecting system of the kidneys. The sinus is bordered laterally by the pyramids, medially by the perirenal space through the renal hilum. The renal sinus contains: lymphatic, nervous, vascular structures, elements of the calyx-pelvic system, surrounded by adipose and fibrous tissue. The hyperechoic component of the sinus is a reflection from adipose tissue. The hypoechoic component - reflection from the vascular elements (when viewed on an empty stomach) The pelvic-pelvic system is not normally visualized when examined on an empty stomach!

    In the study of patients with water load (1 liter of still water 40 minutes - 1 hour before the examination), when the bladder is filled with 200-250 ml, the pelvis and calyx can normally be located in the form of a tree-like hypoechoic structure, splitting the hyperechoic central echocomplex.

    Additional techniques: CDC and EDC Assessment of the blood supply to the renal parenchyma is based on the determination of its vascularization by energy and color Doppler. Doppler settings should be optimized to detect low flow rates.

    According to the method of Hilborn et al (1997), proposed to assess the degree of parenchymal perfusion disorders, there are three degrees of it: degree 0 (normal) - homogeneous staining of blood vessels to the periphery of the cortical substance, degree 1 - vessels do not reach the periphery of the cortex, degree 2 - weak blood flow or lack of it

    Anomalies of renal development 1. Anomalies of position 2. Anomalies of quantity 3. Anomalies of magnitude 4. Anomalies of adhesion 5. Anomalies of structure 6. Anomalies of the PMC 7. Anomalies of the ureter 8. Violations of the vascular-ureteric relationship

    Nephroptosis - the descent of the kidney in orthoposition (standing) When the kidney descends, it not only shifts downward, followed by a number of pathological processes - rotation (rotation) of it along the axis, tension of the renal vessels; the blood supply to the kidney deteriorates, the ureter is bent, contributing to the development of inflammation in the pelvis and the formation of stones.

    There are 3 stages of nephroptosis: at the 1st stage of prolapse of the kidney, there are no clinical manifestations, or there are complaints of general changes in well-being and decreased performance, there are practically no pains. At the 2nd stage of kidney prolapse, pains appear in the lumbar region, aggravated in a standing position, sometimes paroxysmal, protein and erythrocytes are often detected in the urine. At the 3rd stage of nephroptosis, the pain syndrome intensifies, abrupt changes in kidney function join, and performance deteriorates significantly

    Normally, the rib crosses the left kidney 12 along the projection of the middle segment, the right one at the border of the upper and middle segments

    Normal mobility of the kidney is the length of the body of the lumbar vertebra. Exceeding this parameter is the basis for suspicion of nephroptosis. With the I degree of nephroptosis, the lower pole of the kidney descends by more than 1.5 lumbar vertebrae. With nephroptosis of the II degree, the lower pole of the kidney is displaced below 2 lumbar vertebrae. Grade III nephroptosis is characterized by prolapse of the lower pole of the kidney by 3 or more vertebrae.

    Dystopias and Rotation Abnormalities of the position of the kidneys (dystopias) occur when their movement is disturbed during embryonic development from the pelvis to the lumbar region. In this case, the rotation of the kidney is not complete and the pelvis is located in front, and the calyx is located behind (i.e., rotation). The lower the kidney is, the more the rotation process is disturbed. Position anomalies are always accompanied by anomalies of blood supply. With dystopia of the kidney, the renal vessels depart lower than usual, they are often multiple and short.

    Dystopia is simple (homolateral), when the kidney is located on the side of the mouth of its ureter, and cross (heterolateral), if the kidney moves to the opposite side. The ureter of the cross-dystopic kidney crosses the midline and flows into the bladder in the usual place, but ectopia of its mouth is also possible. Depending on the position of the kidney, thoracic, lumbar, iliac and pelvic dystopias are distinguished.

    Thoracic renal dystopia It is extremely rare and is combined with congenital diaphragmatic hernia. The kidney is located above the diaphragm or in the pleural cavity and can be mistaken for a tumor of the chest and mediastinal organs.

    Lumbar kidney dystopia The kidney is located in the lumbar region, located below the usual level, has an unusual flattened or elongated shape and signs of incomplete rotation. The closer to the normal place the kidney is, the fewer signs of abnormal structure are observed in it.

    Iliac dystopia of the kidney With iliac dystopia, the kidney is located at the level of the wings of the ilium, at the entrance to the large pelvis. The kidney also has an abnormal appearance.

    Pelvic Kidney Dystopia The kidney is located in the pelvis, behind the bladder in men, or behind the uterus in women, and can be mistaken for a pelvic tumor. The shape of the kidney is often regular bean-shaped, the ureter is shortened.

    Cross renal dystopia Can be unilateral and bilateral. With cross-unilateral dystopia, the normal kidney is located at the usual level, its shape and size are also normal. Dystopic kidney lies below and medial to the main one. It is reduced and rotated. With cross bilateral dystopia, the ureters are crossed, the kidneys are located below the usual level.

    Abnormalities in the amount Agenesis Doubling Accessory kidney Agenesis Congenital absence of the kidney, combined with agenesis of the ureter and ureteral orifice. In conclusion, we take out: the kidney is not located in its usual place and in the abdominal cavity. The diagnosis requires confirmation. Doubling of the kidney is the most common abnormality.It can be suspected when there are two calyceal systems in one kidney. It can be incomplete, partial and complete.

    Incomplete doubling of the PCS at the level of the pelvis is diagnosed in the presence of two collecting systems of the kidney, drained by the same pelvis and ureter. Partial doubling - when two PCS have their own ureters, merging into one before flowing into the bladder. In cases where two ureters do not merge, but open in the bladder with separate orifices, doubling is considered complete.

    The mouth of the ureter of the lower half is usually located in a normal place, and the mouth of the ureter of the upper half is located lower and medial or ectopic (opens outside the bladder - into the urethra, uterus, vagina, seminal vesicles). Also, the mouth of the upper half may be obstructive or have a ureterocele. The diagnosis requires confirmation.

    Accessory kidney An extremely rare developmental anomaly when an accessory (third) kidney is found. With this malformation, in addition to two normal kidneys, there is another one with separate blood supply and the ureter. Placed more often below normal, and sometimes above it. The accessory kidney is usually small, but it can also be of normal size, sometimes it looks like a rudiment or retains a partial structure. The ureter of the accessory kidney can open as an independent opening in the bladder (sometimes with ectopia) or join at different levels with the ureter of the normal kidney.

    The accessory kidney is usually not clinically apparent. Symptoms appear when hydronephrosis develops in the accessory kidney, stones form, or when its ureter opens outside the bladder, causing urinary incontinence. The diagnosis must be confirmed by intravenous urography, computed tomography or renal angiography, where the course of the renal vessels is clearly visible.

    Anomalies of the size Aplasia: in the projection of the kidney a rudiment without the pelvis and vascular pedicle is located, the diagnosis requires clarification and differentiation with nephrosclerosis Hypoplasia: a kidney of reduced size (by half the size) with normal parenchyma and renal sinus is located, with clear cortico-medullary differentiation, normal staining in the CDC. Vicarious hyperplasia: Vicarious (compensatory) enlargement of the kidney usually occurs with decreased function or the absence of the opposite kidney. In congenital absence of a kidney, the opposite kidney usually has a double volume. The kidney, enlarged in size (volume), with a normal parenchyma and sinus is recalled.

    Fusion abnormalities Horseshoe kidney L-shaped kidney S-shaped kidney I-shaped kidney Galeto-shaped kidney (lumpy kidney)

    Structural anomalies: dysplasias, simple cysts, polycystic dysplasia Dysplasia (multicystic kidney) is a developmental anomaly characterized by the presence of cysts and dysplasia of the renal tissue, can be bilateral and unilateral. With bilateral, the prognosis is poor, with unilateral, with a healthy second kidney, favorable. It is subdivided into atretic variant and hydronephrotic variant. On ultrasound with an atretic variant, cysts are determined, surrounded by echogenic areas of connective tissue, PCS can be defined as an anechoic zone in the center or not. In the hydronephrotic variant, the cysts have a peripheral location around the enlarged pelvis. The function of such a kidney is absent, the size of the kidney is reduced. Often combined with abnormalities in the development of the ureter (agenesis, atresia)

    Simple cysts - On ultrasound, a simple cyst appears as a rounded anechoic mass with a thin echogenic capsule and posterior acoustic enhancement. Cysts with transparent contents are anechoic. The fibrous capsule of the cyst is 1–2 mm thick and looks like a thin echogenic structure. Simple cysts can be single (solitary) and multiple. Simple cysts can be complicated by internal bleeding, suppuration, calcification of the walls, the formation of calculi, a change in shape - such a cyst will already be "atypical"

    By localization, cysts are divided into subcapsular, intraparenchymal, parapelvic. Subcapsular cysts are located under the kidney capsule. Intraparenchymal cysts are entirely surrounded by renal parenchyma. Parapelvic cysts are located in the area of \u200b\u200bthe hilum of the kidney, but do not communicate with the pelvis. There are also pelvic-pelvic (pelvicogenic) cysts communicating with the isthmus with the pelvis or calyx and containing urine - these are diverticula of the pelvis and calyces, which are a developmental anomaly.

    Peripelvic cysts - located between the elements of the PCS and can mimic hydronephrosis. They arise as a result of the expansion of the lymphatic ducts, as a rule, bilateral and are found in old age.

    Signs of atypia cysts. Presence of parietal calcifications Presence of septum or septa Presence of heterogeneous contents (purulent or hemorrhagic) Presence of parietal formations (both hematomas and growths) Irregular cysts Presence of blood flow in the septum or parietal formation

    Polycystic. 1 Autosomal recessive polycystic kidney disease (spongy kidney) is an inherited disorder characterized by non-obstructive dilatation of the collecting ducts, dilatation and malformation of the bile ducts, and fibrosis of the kidneys and liver. This disease is characterized by a combination of simultaneous damage to the kidneys (tubular ectasia and fibrosis) and the liver (congenital liver fibrosis). Forms: perinatal, neonatal, infant (infantile) and adolescent. The disease is inherited in an autosomal recessive manner: parents of sick children may not show signs of the disease, although many families may have more than one child.

    With ultrasonography, the kidneys are dramatically enlarged in size, with smooth contours. The parenchyma looks echogenic due to multiple reflection effects at the boundaries of the cavities and walls of the cysts, its echogenicity is equal to that of the renal sinus. Cortico-medullary differentiation is absent. Sometimes it is possible to find a small number of small cysts.

    In adolescent form, the kidneys appear normal, although moderate enlargement, increased echogenicity of the parenchyma, and decreased cortico-medullary differentiation can be found. Individual cysts can be found in the medullary substance. The greatest changes in this form of the disease are found on the part of the liver and spleen - hepatomegaly, increased echogenicity of the liver, biliary ectasia, splenomegaly, signs of portal hypertension.

    2 Autosomal dominant polycystic kidney disease (adults) is a hereditary disorder characterized by the development of multiple cysts in both kidneys, resulting in parenchymal compression, severe interstitial fibrosis, tubular atrophy, and renal failure.

    Many patients do not complain until symptoms of chronic renal failure appear, such as proteinuria, polyuria, and arterial hypertension. A detailed clinic of the disease usually develops at the age of over 30 years, and the final stage - by the age of 60. Extrarenal cysts are common: liver cysts (polycystic liver disease) are found in 40-75%, pancreatic cysts - in 10%, spleen cysts - in 5% of patients. Cysts have also been described thyroid glandss, endometrium, seminal vesicles, lungs, brain, salivary glands, mammary glands, abdominal cavity, parathyroid glands.

    Ultrasound diagnosis of polycystic kidney disease most often does not cause difficulties: the kidneys are significantly enlarged in size, many cysts are determined, from small to several centimeters in diameter. Large cysts can be complicated by suppuration or hemorrhage. The cavity system of the kidney is poorly differentiated, and the detection of calculi is difficult. The disease is bilateral, but there may be asymmetry - when one of the kidneys looks less affected than the other.

    Ureteral abnormalities High ureteral discharge Ureteral strictures and stenosis Ureteral diverticula Ureteral achalasia Megaureter

    High ureteral discharge is a developmental anomaly in which the pyelourethral segment of the ureter is located at the superior medial edge of the pelvis, this anomaly is one of the causes of hydronephrosis, ultrasound diagnosis is difficult, the diagnosis must be clarified (excretory urography)

    Ureteral strictures - most often localized in the vesicoureteral and ureteropelvic segments, but can be in any part of the ureter.

    Ureteral strictures are unilateral and bilateral, congenital and acquired, single and multiple. Acquired can occur after injuries, damage during instrumental research, bedsores or inflammation caused by the long-term presence of the calculus in the ureter, after surgical interventions on the ureter, tuberculosis and radiation damage. Congenital strictures include compression of the ureter by an abnormal vessel. The diagnosis must be confirmed.

    Ureteral diverticula Ureteral diverticulum is an anomaly in the development of the ureter, which is a saccular protrusion of the wall of the ureter or a tubular formation of various lengths connected to it. The inside of the diverticulum is covered with urothelium, the submucosal layer is usually poorly expressed. Muscle fibers are randomly located. Diverticula are localized almost exclusively in the pelvic ureter. The diagnosis must be confirmed.

    Megaureter - enlargement of the ureter - is divided into congenital and acquired. The cause of the congenital is considered to be insufficient development of the neuromuscular apparatus of the ureter (neuromuscular dysplasia). Congenital megaureter is always bilateral! The reason for the acquired is the presence of an obstacle localized at the level of the lower parts of the ureter.

    In the development of the disease, 3 stages are distinguished. Its initial stage is achalasia of the ureter - the ureter is dilated only in the lower third, this is the stage of compensation. At the second stage (megaloureter), the ureter is dilated throughout, i.e., the compensatory capabilities of the muscular membrane are exhausted. In the third stage, ureterohydronephrosis develops. Ultrasound picture: stage 1 - expansion of the ureters at the level of the lower thirds. Stage 2 - the ureters are sharply expanded throughout, elongated, as a result of which they bend in the retroperitoneal space in the most bizarre way. The diameter of the ureters can be as large as the diameter of the small intestine. Stage 3 - dilated ureters, pelvis and calyx are located, the structure of the renal parenchyma can be changed or unchanged depending on the duration of the disease.

    Non-neoplastic diseases of the kidneys Inflammatory diseases of the kidneys Urolithiasis Diffuse diseases of the parenchyma Trauma

    Inflammatory diseases Acute pyelonephritis Apostematous pyelonephritis Carbuncle Abscess Pyonephrosis Paranephritis Tuberculosis

    Acute pyelonephritis is an acute inflammatory process caused by nonspecific microflora and proceeding in the calyx-pelvic system and tubulo-interstitial zone. It is divided into diffuse and focal, serous and purulent-destructive. There are no typical ultrasound signs! Most often, even with an established diagnosis, we see an ultrasound picture of the norm. Changes are often one-sided, possibly an increase in the volume of the kidney, rounded shape, thickening of the parenchyma, increased echogenicity of the parenchyma (due to edema), the appearance of the syndrome of "prominent pyramids" - visualization of hypoechoic pyramids against the background of hyperechoic cortex, decreased differentiation of the sinus-parenchyma. Some authors note the presence of thickening and layering of the walls of the pelvis.

    Apostematous pyelonephritis is a diffuse purulent-destructive inflammation, characterized by the appearance of small abscesses (apostem). There are no typical ultrasound signs! The kidney is often increased in volume, it is possible that the cortical-cerebral and sinus-parenchymal differentiation is disturbed, and the echogenicity of the parenchyma decreases. Sonographic detection of apostems is not possible in most cases.

    Carbuncle is a zone of inflammatory infiltration with a tendency to purulent fusion. At the beginning of the disease, the carbuncle looks like a site of increased or decreased echogenicity in the kidney parenchyma, with a fuzzy and uneven outline. Then, as the purulent fusion proceeds, a hypoechoic inhomogeneous focus appears and begins to grow in the central zone - pus with tissue detritus - an abscess is formed.

    An abscess is a focal form of purulent-destructive inflammation of the kidney, characterized by the presence of a heterogeneous hypoechoic area of \u200b\u200bnecrosis, surrounded by an echogenic contour of the infiltrated parenchyma. Against the background of antibacterial and anti-inflammatory therapy, the inflammatory process is cured with the formation of a scar. Without treatment, the abscess breaks out into the perirenal tissue with the development of a perirenal abscess and purulent paranephritis.

    Pyonephrosis - is the final stage of purulent-destructive pyelonephritis. The pyonephrotic kidney is an organ with massive purulent fusion of the parenchyma and the involvement of perinephric tissue in the process. The volume of the kidney is increased. The parenchyma is hypoechoic and heterogeneous, the contour is uneven and indistinct, calculi and echogenic pus can be found in the renal cavity system. The term "pyonephrosis" is also used in relation to the hydronephrotic transformed kidney, the cavity system of which is filled with purulent urine.

    Paranephritis is an inflammatory process in the peri-renal fatty tissue. Most often it is the result of the spread of pus from the focus of inflammation in the kidney. Depending on the localization of the focus, paranephritis is anterior, posterior, upper, lower and total. Ultrasound diagnostics of paranephritis is based on the detection of a lesion in or around the kidney without clear contours, a heterogeneous structure due to pus of different acoustic density, and imbibed fiber.

    Tuberculosis is a consequence of the hematogenous spread of the pathogen from the primary foci, most often the lungs or intestines. There are no typical ultrasound signs! The structure and echogenicity in the initial stages are not changed. With caseous decay and the formation of caverns in the parenchyma, hypo and anechoic foci with irregular contours and opaque internal contents may appear. Subsequently, the cavities are emptied, fibrosis and calcification (calcification) of the affected areas of the renal parenchyma develop. In later cases, the entire kidney may undergo calcification (tuberculous autonephrectomy). With the defeat of the pelvic-ureteric segment, a picture of hydronephrosis develops.

    Xanthogranulomatous pyelonephritis is a rare form of chronic inflammatory process of the kidney. The disease is characterized by gradual destruction of the renal parenchyma and its replacement with xanthogranulomatous tissue. Histologically, xanthomal, fatty-like cells are found. It can be diffuse and focal (pseudotumor). There are no typical ultrasound signs! The kidney can be enlarged, one or more anechoic, hypoechoic or hyperechoic foci that alter the normal cortico-medullary differentiation and deform the central echo complex are determined in the parenchyma. In the pelvis, coral calculus can be determined. To clarify the diagnosis, it is necessary to conduct a puncture biopsy.

    Hemorrhagic fever with renal syndrome is a zoonotic natural focal viral infectious disease. The source of infection is rodents (bank vole, great vole, field and forest mice), which excrete the virus in urine and feces. Infection of a person occurs by airborne dust - by inhaling dust containing dried particles of rodent excrement with air, as well as by alimentary means and through damaged skin in contact with rodents and their excrement. The possibility of infection of people from each other has not been established. The rise in the incidence occurs in the summer and autumn months, which is due to field work, a massive departure of citizens out of town.

    The disease is characterized by selective damage to blood vessels and proceeds with fever, intoxication and kidney damage, which can lead to the development of acute renal failure, rupture of the kidney, azotemia, and uremic coma. Macroscopically, dystrophic changes, serous hemorrhagic edema - and hemorrhages are revealed in the internal organs. The kidneys are enlarged, hemorrhages are found under the capsule. The cortical substance is pale, the medullary layer is purple-red, with multiple hemorrhages in the pyramids and pelvis, there are foci of necrosis. Sonographically, the picture is nonspecific, the kidneys can be symmetrically enlarged, the echogenicity of the parenchyma is increased with smoothed cortico-medullary differentiation, subcapsular hematomas and rupture of the renal parenchyma can be detected.

    Concrements are sonographically hyperechoic, round or oval structures that give an acoustic shadow. They are located within the calyx-pelvis system. On devices of the expert class, we can see calculi with a size of 3 -3.5 mm (in the presence of echo) and more, anything less is doubtful! Ultrasound diagnosis "kidney sand" and "microliths" does not exist! The following structures imitate small calculi: - calcified vessel walls - calcifications of the papillae of the pyramids - cysts with parietal calcifications - diverticula of the pelvis and calyxes with calcifications Coral-like calculus - a stone of an irregular "coral" shape, located mainly in the pelvis in the calyx and giving out spurs and large sizes (up to 5-6 cm), as a rule, causes dilatation of the pelvis and calyces

    Complications of urolithiasis The most serious complication is a disturbance of urodynamics due to the ingress of a calculus into a narrow section of the CSF and ureter, with the formation of hydronephrosis. Localization: The cervix of the calyxes, with the formation of calyxectasia Pelvic-ureteric segment, with the formation of pyelectasia. The width of the pelvis in this area is reduced to 2-3 mm. The area where the ureter crosses the upper edge of the entrance to the pelvis, with the formation of ureteroectasia. When crossing with the iliac vessels, where the diameter of the ureter narrows to 3-4 mm, the vesicoureteral segment. The ureter in this area is narrowed to a diameter of 2-4 mm.

    Diffuse parenchymal diseases Ultrasound manifestations of a large number of chronic kidney diseases are nonspecific and are characterized by diffuse changes parenchyma. These include: immune diseases (glomerulonephritis), congenital anomalies in the development of parenchymal structures (glomerulopathy, tubulopathy), amyloidosis, diabetic nephropathy, systemic diseases and vasculitis (kidney damage in SLE, periarteritis nodosa, Wegener's granulomatosis, Gudpasenchain's syndrome, thrombocytopenic purpura in adults and hemolytic uremic syndrome in children), bacterial septic endocarditis and AIDS.

    At the onset of the disease, the ultrasound picture is not changed. With progression, the kidneys are often enlarged. Bilateral damage is characteristic. The echogenicity of the parenchyma is increased, the syndrome of "protruding pyramids" appears, cortical-cerebral differentiation is preserved. Subsequently, there is a decrease in cortical-medullary differentiation, the parenchyma is heterogeneously increased echogenicity, then a decrease in the volume of the kidneys begins, a thinning of the parenchyma, irregularities and blurred contours appear. At the stage of nephrosclerosis, the kidney is practically indistinguishable from the surrounding tissue.

    Kidney injury. The most common classification of kidney injuries H. A. Lopatkin (1986). 1 - kidney contusion, occurs in 80% of cases, microscopically there are multiple hemorrhages in the renal parenchyma in the absence of its macroscopic rupture and subcapsular hematoma. 2 - damage to the fatty tissue surrounding the kidney and ruptures of the fibrous capsule, which may be accompanied by small tears of the kidney cortex. In the perirenal tissue, a hematoma is found more often in the form of blood imbibition. 3 - subcapsular rupture of the parenchyma, not penetrating into the pelvis and calyx. A large subcapsular hematoma is usually present.

    4 - ruptures of the fibrous capsule and parenchyma of the kidney with spread to the pelvis or calyx. Such a massive injury leads to hemorrhage and urine leakage into the perirenal tissue with the formation of urohematoma. Clinically similar lesions are characterized by profuse hematuria. 5 - crushing of an organ, in which other organs of the abdominal cavity are often damaged. 6 - detachment of the kidney from the renal pedicle, as well as isolated damage to the renal vessels, while maintaining the integrity of the kidney itself, which is accompanied by intense bleeding and can lead to the death of the victim.

    Tumor diseases of the kidneys Benign: organ-specific and organ-supported Malignant: organ-specific and organ-provided Tumors in diseases of hematopoietic and lymphoid tissue Metastatic tumors

    Benign tumors Benign tumors are more often characterized by a homogeneous structure, correct shape, evenness and clarity of contours, non-invasive growth, but this does not allow to exclude cancer! Organ-specific: adenomas, angiomyolipomas, urothelial papillomas

    1. Adenoma - morphologically renal adenoma is similar to highly differentiated renal cell carcinoma, and there is a hypothesis that it is an early form of renal adenocarcinoma. According to the general histological structure, adenomas can be acinar and tubular, papillary, solid, trabecular, cystic, mixed, fibroadenomas. Adenomas include only well-differentiated tumors no more than 1 cm in diameter. Adenoma more than 3 cm in diameter is considered a malignant tumor.

    2. Angiomyolipoma - the most common finding during ultrasound, has a fairly typical picture: a hyperechoic homogeneous formation with a clear contour, located in the parenchyma or sinus, angiolipomas can be multiple in nature. Small angiolipomas are avascular, large ones have single vessels.

    3. Urothelial papilloma - 5-10% of primary renal tumors and develops in the lining of the pelvis. These are benign papillomas and papillary carcinomas. Benign papillomas are difficult to distinguish from highly differentiated papillary cancers. Macroscopically, papilloma is usually a delimited, dense or soft tumor on a thin long or short stalk, less often on a broad base. In rare cases, papillomas reach large sizes. The surface of the papilloma is uneven, fine or coarse-grained, resembles cauliflower or cockscombs, can be compacted due to the deposition of calcium salts

    Organ-nonspecific: leiomyomas, rhabdomyomas, neurinomas, lymphangiomas Leiomyoma is a benign mesenchymal neoplasm and is usually formed from the smooth muscles of the renal capsule; in addition, the source of the development of leiomyoma can be the muscle tissue of the pelvis or the muscle elements of the vessels of the renal cortex. Usually the tumor does not exceed a few millimeters, has no clinical symptoms and is an accidental finding. Along with this, casuistic observations of giant leiomyomas are described. Leiomyomas have a solid structure, clear even contours. Their echogenicity is often lower than the echogenicity of the renal parenchyma.

    Rhabdomyoma, a kidney swelling built of striated muscle tissue that is not normally part of the kidney, is extremely rare. A number of researchers attribute renal rhabdomyoma not to true tumors, but to teratomas. Histologically, the tumor consists mainly of intertwining bundles of striated muscle fibers with transverse and longitudinal striation. Neurinoma (schwannoma) is a benign formation arising from the cells of the myelin sheath of the cranial, spinal and peripheral nerves. Extremely rare.

    Lymphangioma is a benign tumor of the lymphatic system, the microscopic structure of which resembles thin-walled cysts of various sizes from 0.2-0.3 cm to large formations. Lymphangiomas account for approximately 10-12% of all benign lesions in children. Distinguish between simple, cavernous and cystic lymphangiomas. According to many authors, it occupies an intermediate position between a tumor and a malformation. Lymphangioma has limited growth, does not undergo malignancy. The predominant localization of lymphangiomas is skin, subcutaneous tissue. In some cases, lymphangioma can develop in the tissues of the tongue, liver, spleen, kidneys, as well as in the tissue of the mediastinum and retroperitoneal space.

    Renal cell carcinoma (adenocarcinoma, hypernephroma) accounts for 80% of all renal tumor lesions. Sonographically, it has 4 main types of structure: 1 -c solid type - the most common. The tumor looks like an iso- or hypoechoic formation of a rounded shape with clear contours, a pseudocapsule of fibrous tissue can be determined, which arises from compression and ischemia of tissues at the border with adjacent areas of the parenchyma, "small" (< 3 см) опухоли могут иметь повышенную эхогенность и могут напоминать ангиомиолипому, но обычно имеют гипоэхогенный ободок по периферии, внутриопухолевые кисты. Опухоль больших размеров может содержать кистоподобные участки некротического распада и кальцинаты.

    2 - infiltrative (sarcoma-like) - the tumor spreads towards the gate of the kidney, infiltrating the structures of the central echo complex, the kidney retains its bean-like shape, but changes its structure to diffusely heterogeneous. 3 - multicystic - a formation with a small-cell structure is determined, resembling a multilocular cyst. In contrast to the latter, the inner walls of the tumor are of low echogenicity and are often unevenly thickened. 4 - Very rarely, renal cell carcinoma can occur in the wall of a simple cyst. The tumor looks like a tissue structure on the inner surface of the cyst wall with internal blood flow in CDC and ED. The content of the cyst can be anechoic, as well as heterogeneous, hiding tumor tissue.

    Wilms' tumor - nephroblastoma - is a malignant tumor of the kidney that develops from metanephrogenic tissue (embryonic kidney tissue). Nephroblastoma ranks fifth in frequency among all malignant diseases in children. Age peak incidence occurs at 3 years, although the tumor is considered congenital. Boys and girls get sick equally often, a tumor can occur in any part of the kidney. In approximately 5% of patients, primary bilateral kidney damage is observed. It is extremely rare that nephroblastoma can occur extrarenally during the embryonic migration of metanephrogenic tissue.

    There are two main types of nephroblastoma: 1. Nephroblastoma with favorable histological structure 2. Nephroblastoma with unfavorable histological structure

    In tumors with an unfavorable histological structure, the nuclei of tumor cells are very large and altered, this condition is called anaplasia. The more pronounced the phenomena of anaplasia, the worse the outcome of the disease. For a long time, the tumor grows in the kidney capsule, however, even in the initial periods of tumor growth, its hematogenous and lymphogenous metastasis can be noted. Metastases most commonly affect the lungs, liver, bones and retroperitoneal lymph nodes

    A favorable histological structure means no signs of anaplasia and a good prognosis. In 95% of cases, a favorable histological structure of nephroblastoma is revealed - this type of nephroblastoma is diagnosed only when they reach large sizes, the average weight of such a nephroblastoma is about 500 grams.

    Organ-nonspecific: tumors of mesenchymal origin Renal sarcoma is a rare neoplastic disease of the connective tissue of the kidney, which occurs in less than 1% of cases. Its manifestations are the same as in renal cell carcinoma: hematuria, pain in the side, or a palpable tumor in the abdomen. It can be very difficult to distinguish kidney cancer from sarcoma without instrumental diagnostic methods, therefore an accurate diagnosis is usually determined after CT or MRI. Sarcoma can lead to heterogeneous areas of necrosis and hemorrhage. Retroperitoneal sarcomas can invade the kidney.

    Tumors in diseases of hematopoietic and lymphoid tissue: Ultrasound examination in lymphoma reveals the following variants of changes: (1) diffuse enlargement of the kidneys (2) focal formation in the renal parenchyma (3) multiple focal formations in the parenchyma (4) focal formation within the renal sinus ( 5) peri-ureteric and peri-ureteric infiltration, a kidney condition resembling hydronephrosis (6) invasion of the kidney by the formation of a retroperitoneal space (7) infiltration of retroperitoneal tissue resembling a perrenal hematoma

    Metastatic tumors: Sources of focal metastatic lesions of the kidneys are tumors of the lungs, stomach, uterus and appendages, intestines, the opposite kidney, as well as the pancreas, mammary and thyroid glands. It is possible to suspect metastatic kidney damage if multiple (two or more) foci of similar echostructure are found in one or both kidneys.

    Classification ТМ N Тх - insufficient data to assess the primary tumor Т 0 - the primary tumor is not detected Т 1 - the tumor is not more than 7 cm in the largest dimension, limited by the kidney T 1 a - the tumor is not more than 4 cm T 1 b - the tumor is more than 4 cm, but less than 7 cm T 2 - a tumor more than 7 cm in the largest dimension, limited by the kidney T 3 - the tumor spreads into large veins, or there is an invasion of the adrenal gland or surrounding tissues, but there is no tumor exit outside the Gerota fascia. T 3 a - tumor invasion of the adrenal gland or perirenal tissue within the fascia of Gerota. T 3 b - the tumor spreads to the renal vein or to the inferior vena cava below the diaphragm. T 3 s - the tumor spreads into the inferior vena cava above the diaphragm or there is an invasion of the inferior vena cava wall. T 4 - the tumor extends beyond Gerot's fascia.

    N x Regional lymph nodes cannot be assessed. N 0 - no metastases in regional lymph nodes. N 1 - metastasis in one regional lymph node. N 2 - metastases in more than one regional lymph node. Mx - Distant metastases cannot be assessed. M 0 - no distant metastases. M 1 - distant metastases

    Prevalence of the tumor process After visualization of the tumor, it is necessary to determine the localization, echostructure, echogenicity, contour, size, connection with the pyelocaliceal system and the vascular pedicle of the kidney, the presence of a tumor thrombus in the renal and inferior vena cava, invasion into the adrenal gland, spread to the perinephric tissue and beyond Gerota's fascia (uneven, indistinct contours, lack of mobility during breathing, no border between the tumor and the adjacent structures: liver, spleen, pancreas, intestinal loops, muscles of the lateral or posterior abdominal wall).

    Identification of metastatic lesions lymph nodes: examination of the lymph nodes at the hilum of the kidney, near the aorta and the inferior vena cava around, above and below the renal vessels. Metastases can occur in the posterior mediastinum and left supraclavicular region. Metastases to distant organs: metastases to the liver, bones, adrenal glands, and lungs are typical.

    CDK of tumor lesion According to the vascular picture, 5 types of blood supply to focal kidney formations are distinguished (Jinzaki et al (1998)) type 0 - no signal, type 1 - intratumoral and focal signals, type 2 - penetrating vessels, type 3 - peripheral blood supply, type 4 - mixed peripheral and penetrating blood supply. It is believed that types 0, 1, 2 are not typical for kidney cancer, with this disease types 3 and 4 are more common. With angiomyolipomas, types 1 and 2 are more common. For kidney cysts, type 0 is characteristic of blood supply.

    Differential diagnosis Differentiate kidney tumors from: 1. "Humpback" kidney 2. Renal column hypertrophy (Bertini columns) 3. Renal cysts, especially with inhomogeneous contents, septa and parietal inclusions 4. Abscesses and carbuncles 5. Xanthogranulomatous pyephelonephritis 6. Paranephritis .Paranephral hematoma

    Hyperechoic inclusions are usually found during kidney ultrasound. They represent certain areas of tissue with large acoustic seals, which can be simple stones from urolithiasis or be dangerous formations in the form of a benign or malignant tumor. These are structures that are denser in comparison with the surrounding tissues of the organ, perfectly beating ultrasound and thereby creating hyperechoicity. On the monitor of the ultrasound machine, they are indicated by white spots.

    What are hyperechoic inclusions?

    On ultrasound of the kidneys, such neoplasms are visualized as small linear, point or volumetric structures with a high echogenicity index. They are located within the renal tissue. In medical practice, it is noted that such hyperechoic inclusions are a kind of calcifications, from which microcalcifications are emitted - point particles without accompanied by an acoustic shadow. If the presence of microcalcification is diagnosed in a nodular formation, then many doctors talk about the development of a malignant tumor.

    Quite often, experts come to this very opinion, since hyperechoic formations generally begin to manifest themselves precisely in malignant tumors. In a malignant tumor, three types of structures are distinguished:

    1. psammous little bodies - make up half of the echogenic formation;
    2. calcifications - only 30%;
    3. areas of sclerosis - 70%.

    In a benign kidney tumor, psammomny bodies are completely absent, calcifications can also be found quite rarely. These are mainly sclerotic areas.

    Varieties of hyperechoic inclusions. Diagnostics

    Only a specialist is able to detect hyperechoic inclusions in the kidneys during diagnosis. These can be stones or sand in the kidneys. Today, several varieties of such inclusions are known:

    1. point inclusions, which are rendered quite brightly: they are small and do not have an acoustic shadow;
    2. large formations that also lack acoustic shadow. In the kidneys, they are rarely formed, doctors mainly diagnose them during an ultrasound of the kidneys. They can be localized not only in a malignant, but also in a benign tumor;
    3. large formations, which include an acoustic shadow. They are fully consistent with the sclerotic parts.

    Hyperechoic inclusions in the kidneys can be detected by ultrasound of the kidneys, or their presence can be suspected by severe symptoms:

    • elevated temperature
    • discoloration of urine
    • frequent colic in the kidney area,
    • severe pain in the abdomen or below the belt or persistent pain in the groin,
    • vomiting and nausea.

    These symptoms are similar to the manifestations of other diseases, therefore, at the first suspicion of kidney stones, you should immediately consult a doctor. In order not to start the disease, it is necessary to undergo a full examination every six months, take blood, urine, and feces for analysis. Thus, it is possible not only to prevent the development of any diseases, but also to avoid some diseases.

    For the prevention of stones in the stomach, it is necessary to frequently consume liquid: water, rose hips, tea with herbs (mint, oregano, mountain ash, etc.). This will cleanse the body of toxins and salts through frequent urination.

    Diseases caused by hyperechoic kidney inclusions. Treatment

    In most cases, hyperechoic kidney inclusions appear in the form of:

    • inflammatory process: carbuncle, kidney abscess.
    • cyst-like growths (usually they contain liquid).
    • hemorrhage in the kidney (a kind of hematoma).
    • kidney tumors (benign or malignant).

    If the doctor suspects the above diseases, he sends the patient for a comprehensive examination using MRI. In some severe cases, a kidney biopsy is required.

    It is not easy to cure hyperechoic inclusions, but it is possible. The stones are taken out in two main ways. The first method is based on frequent urination, for which special diuretic herbs or medicines prescribed by a doctor are used. The second method is the removal of stones using laser beams, when they are crushed. The first method can be used to treat small stone formations, no more than 5 mm. In the case of an advanced disease, the kidney is removed, then chemotherapy is prescribed in order to remove the remaining formations. In such drastic situations, a constant diet is necessary.

    Remember: only a specialist can make an accurate diagnosis. Based on the ultrasound of the kidneys and the test results, he will prescribe the appropriate treatment. Never self-medicate - this can make the situation worse.

    Parenchyma of the kidney and its pathology

    It happens that you have heard a word and even intuitively understand what it is about, but you cannot clearly articulate your knowledge. It seems to me that "parenchyma" is just such a word.

    The resulting uncertainty can be understood, because this term does not mean something definite. Historically, the term "parenchyma" was introduced to distinguish the totality of tissues that fill an organ from its outer shell and internal bridges that extend from this shell. This term describes structures of different origin or functionality, which are located in the space between the connective tissue framework of an organ called the stroma. Schematically, the structure of the organ can be represented as follows: from the outside, the organ is covered with a sheath of connective tissue, often containing smooth muscle fibers.

    From this shell, partitions - trabeculae depart into the thickness of the organ, along which nerves, lymphatic and blood vessels penetrate inside. The lumen between these partitions is filled with the working part of the organ - the parenchyma. It is different in different kinds of organs: the parenchyma of the liver is glandular tissue, in the spleen it is the reticular connective tissue. The parenchyma can have a different structure and within one organ, for example, as the cortex and medulla. Organs rich in parenchyma are called parenchymal.

    Internal organization of the kidneys

    Based on the above, we can say for sure that the kidney is a parenchymal organ. Outside, she has a fibrous capsule containing many myocytes and elastic fibers. On top of this shell there is also a capsule of adipose tissue. This entire complex, together with the adrenal glands, is surrounded by a thin connective tissue fascia.

    Parenchyma of the kidney, what is it? On a longitudinal section, you can see that the flesh of the organ is represented as if in two layers, different in color. Outside, there is a lighter cortical layer, and a darker cerebral layer is located closer to the center. These layers mutually penetrate each other. Parts of the medulla in the cortical are called "pyramids" - they look like rays, and parts of the cortical parenchyma form between them "Bertin's pillars". With their wide part, the pyramids face the cortical layer, and with their narrow part (renal papilla) - towards the inner space. If we take one pyramid with adjacent cortex, we get the renal lobe. In a child under 2-3 years old, due to the fact that the cortical layer is not yet sufficiently developed, the lobules are well defined, i.e. the kidney has a lobular structure. In adults, the lobulation practically disappears.

    Both layers of the renal parenchyma are formed by different sections of the nephrons.

    Nephron is a mini filter, consisting of different functional departments:

    • renal corpuscle (glomerulus in the capsule - "Bowman's capsule");
    • tubule (it defines the proximal section, the loop with the descending and ascending part - "Henle's loop" and the distal section).

    The cortex is formed by the renal corpuscles, proximal and distal parts of the nephron. The medulla and its protrusions in the form of rays are formed by the descending and ascending parts of the loops of the cortical nephrons.

    In the middle you can see the pelvis-calyx system. After filtration and re-absorption, which occurs in the nephrons, urine through the renal papillae enters the small, and then into the large renal cups and the pelvis, which passes into the ureter. These structures are formed by mucous, muscle and serous tissues. They are located in a special deepening called "renal sinus".

    Measured indicators

    Like any organ, the kidneys have their own norms of health indicators. And if laboratory methods for examining urine and monitoring the rhythm of urination are used to assess the functionality of the kidneys, then the integrity of the organ, its acquired or congenital anomalies can be judged by ultrasound, CT (computed tomography) or MRI examination. If the obtained indicators fit into the norm, it means that the kidney tissue has not suffered, but this does not give a reason to talk about the preservation of its functions.

    Normally, the size of this organ of an adult reaches 10-120 mm in length and 40-60 mm in width. The right kidney is often smaller than the left. With a non-standard physique (too large or fragile), not the size, but the volume of the kidney is assessed. Its normal value in numerical terms should be twice the body weight ± 20 ml. For example, with a weight of 80 kg, the volume norm is from 140 to 180 ml.

    Echostructure of the kidney

    Ultrasound evaluates organs and tissues for their ability to reflect or transmit ultrasonic waves. If waves pass freely (the structure is hollow or filled with liquid), then they speak of its anechogenicity, echo-negativeness. The denser the tissue, the better it reflects ultrasound, the better its echogenicity. Stones, for example, show themselves as structures with increased echogenicity (hyperechoic).

    Normal ultrasound in the kidney has a heterogeneous structure:

    • pyramids are hypoechoic;
    • cortical substance and pillars are isoechoic (the same among themselves);
    • sinuses are hyperechoic due to connective, fibrous, adipose tissues and the vessels and tops of the pyramids located there. The calyx-pelvic complex is not normally visualized.

    Pseudopathology

    In some cases, with ultrasound, what, at first glance, seems to be a pathology, is not it. So, often the enlarged columns of Bertin go deep enough beyond the parenchyma into the renal sinus. It seems that this parenchymal bridge literally divides the kidney in two. However, all structures that make up the bridge are normal. renal tissue... Often, enlarged Bertin columns or such bridges are mistaken for a tumor.

    Various variants of the structure of the calyx-pelvic system should not be attributed to pathology. There are a great many options for their configuration, even in one person the structure of the right and left kidneys is individual. This also applies to the anatomical structure of the renal parenchyma.

    Partial doubling of the kidney can be considered ambiguous. At the same time, the parenchymal constriction divides the sinus into two, as it were, separate sections, but the complete bifurcation of the pelvis does not occur. This condition is considered a variant of the norm and generally does not bring discomfort.

    Diseases affecting the renal parenchyma

    Tuberculosis

    Usually kidney damage occurs in the background common disease organism. Mycobacterium tuberculosis enters the kidneys with blood flow, less often lymph, or through the urinary tract. As a rule, the disease affects both organs at once, and when it progresses in one of the kidneys, in the other at this time it is in a dormant state.

    A specific change in the parenchyma is characterized by the appearance of tuberculous tubercles in the cortex. Further, the process goes to the medulla and renal papillae. The tissues ulcerate, cavities (cavities) are formed, tuberculous tubercles continue to appear around these cavities, creating an even larger area of \u200b\u200btissue decay. When this process is transferred to the renal sinus and ureter, the kidney functions are turned off with impaired urination.

    In addition to direct damage to the renal parenchyma, tuberculosis provokes the formation of calcifications. Calcinate is a process of replacing damaged tissue, an irreversible change due to the deposition of calcium salts.

    Treatment of calcifications does not imply its "crushing" or drug destruction. They by themselves are able to dissolve after recovery from the underlying disease that caused tissue damage.

    Therapy for renal tuberculosis involves anti-tuberculosis drugs - Isoniazid, Streptomycin and Rifampicind for intravenous administration, with a switch to oral forms. Treatment is long - a year and a half. At the same time, surgical removal damaged kidney tissue.

    Tumor process

    A kidney tumor is quite common because it can be caused by a variety of causes:

    Regarding the nature of the kidneys, tumors can be primary - arise in the kidney itself or secondary - grow from other organs. By the nature of growth, tumors are divided into benign and malignant. Among malignant neoplasms of the kidneys, the first place is occupied by hypernephroid (renal cell) cancer, which is located mainly in the cortical layer. However, it can also be found in the medulla and sinus. Nonhypernephroid cancer and sarcoma are also distinguished. The difference is in the nature of the tissue from which the tumor develops.

    Mixed tumors stand apart. They are most common in children, as they develop from still undifferentiated tissues in the embryonic stage. In such mixed tumors, areas of adipose, muscle and nervous tissues are determined at the cellular level.

    On ultrasound, the malignant formation has an irregular shape, without clear boundaries with the possible inclusion of vessels. Calcifications and cysts may also be present at sites of parenchymal necrosis.

    It is possible to reliably distinguish benign from malignant tumors only with the help of a biopsy.

    Urolithiasis disease

    The formation of stones is a physicochemical process, during which from a supersaturated saline crystals are formed. In the kidneys, this process is regulated by special enzymes, in the absence of which the function of the nephron tubules is disturbed, the content of salts in the urine increases, the conditions for their dissolution change and they fall out in the form of a sediment. The stones cause sclerosis and atrophy of the renal pelvis, from where the process can spread to the parenchyma. Its functional units die and are replaced by adipose tissue, and the kidney capsule thickens.

    Large stones can block the flow of urine from the pelvis through the ureter. Due to the increasing intrarenal pressure, the ureter expands, and then the calyx-pelvis complex. With prolonged blockage of the ureteral duct, not only the affected kidney loses its functional ability, but also the second organ too.

    Parenchymal symptoms and treatment prospects

    Damage to the renal parenchyma affects its functions - filtration and excretory, which is immediately reflected in the state of the whole organism.

    Weakness and signs of intoxication appear; the temperature rises; the skin color changes, it becomes dry; the rhythm and volume of urination is disturbed; blood pressure rises; swelling is formed on the face, arms and legs; laboratory parameters of urine change, and with the naked eye, turbidity, pus or blood is determined in it.

    The urologist has in his arsenal a variety of instrumental and laboratory research methods in order to determine the cause of kidney disease and prescribe adequate treatment.

    The good news is that the kidney is able to function while preserving even 1/3 of the organ. The restoration of the parenchyma occurs not due to the formation of new nephrons, but due to an increase in those preserved under the influence of neurohumoral regulation. For this it is necessary to stop the action of the damaging factor. Then conditions are created in the organ for the restoration of microcirculation and hemodynamics, which underlies the renewal of kidney function. Unfortunately, if the kidney tissue is sclerosed and there is no possibility of its vascularization (germination by vessels), then the function cannot be restored.

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