Sea buckthorn oil Gorno-Altai instructions for use. Sea buckthorn oil "Gornoaltaiskoe" - description and instructions for use

Famar Orleans

Country of origin

France

Product group

Preparations for colds and flu

ARI and "cold" symptoms remedy (non-narcotic analgesic agent + alpha-adrenergic agonist + H1-histamine receptor blocker + vitamin).

Release forms

• Powder for preparation of oral solution (lemon), 22.1 g per sachet-sachet - 14 pcs.

Description of the dosage form

• Loose white granular powder with yellow impregnations without foreign particles with a citrus scent. The presence of soft lumps is allowed.

Pharmacokinetics

Paracetamol Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. After taking the drug inside, the maximum concentration of paracetamol in plasma is reached after 10-60 minutes. Paracetamol is distributed in most body tissues, crosses the placenta and is present in breast milk... At therapeutic concentrations, binding to plasma proteins is insignificant, increasing with increasing concentration. It undergoes primary metabolism in the liver, excreted mainly in the urine of glucuronide and sulfate compounds. The half-life is 1-3 hours. Pheniramine maleate The maximum plasma concentration of pheniramine maleate is reached after about 1-2.5 hours. The half-life of feniramine maleate is 16-19 hours. 70-83% of the dose taken is excreted in the urine in the form of metabolites or unchanged. Phenylephrine hydrochloride Phenylephrine hydrochloride is absorbed from the gastrointestinal tract and undergoes primary metabolism in the intestine and liver. It is excreted in the urine almost completely in the form of sulfate compounds. Peak plasma concentrations are reached between 45 minutes and 2 hours. The half-life is 2-3 hours. Ascorbic acid Ascorbic acid is rapidly and completely absorbed from the gastrointestinal tract, binding to plasma proteins is 25%. In case of overdose vitamin C excreted in the form of metabolites in the urine.

Special conditions

To avoid toxic damage to the liver, taking the drug should not be combined with alcoholic beverages... TeraFlu® for influenza and colds contains: sucrose 20 g per sachet. This should be taken into account in patients with diabetes mellitus. Patients with rare hereditary problems such as fructose intolerance, glucose-galactose malabsorption or sucrase / isomaltase deficiency should not take TeraFlu® for colds and flu. dye sunset yellow (E110). May cause allergic reactions. sodium 28.3 mg per sachet. This should be taken into account in patients on a sodium diet. Do not use the drug from damaged sachets. Patients should see a doctor if: There is bronchial asthma, emphysema, or chronical bronchitis; Symptoms persist within 5 days or are accompanied by severe fever for 3 days, rash, or persistent headache. These could be signs of more serious violations. Impact on the ability to manage vehicles and the mechanisms of TheraFlu® from flu and colds can cause drowsiness, therefore, during treatment, it is not recommended to drive a car and engage in other activities that require concentration of attention and a high speed of psychomotor reactions.

Composition

• One packet contains:
• Active ingredients: paracetamol 325 mg, phenylephrine hydrochloride 10 mg, pheniramine maleate 20 mg, ascorbic acid 50 mg.
• Excipients: sodium citrate dihydrate 120.74 mg, malic acid 50.31 mg, sunset yellow dye 0.098 mg, quinoline yellow dye 0.094 mg, titanium dioxide 3.16 mg, lemon flavor 208.42 mg, tribasic calcium phosphate 82 mg , citric acid 1221.79 mg, sucrose 20,000 mg.

TeraFlu for flu and colds indications for use

• Symptomatic treatment of infectious and inflammatory diseases (ARVI, including influenza), accompanied by high fever, chills, body aches, headaches and muscle pain, runny nose, nasal congestion, sneezing.

TeraFlu for flu and colds contraindications

• Hypersensitivity to the individual components of the drug, concomitant use of tricyclic antidepressants, beta-blockers or other sympathomimetic drugs, concomitant use of monoamine oxidase (MAO) inhibitors or during the previous 2 weeks, portal hypertension, alcoholism, diabetes, sucrase / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, pregnancy, period breastfeeding, childhood under 12 years of age, severe cardiovascular disease, arterial hypertension, hyperthyroidism, angle-closure glaucoma, pheochromocytoma.
• Carefully:
• With severe atherosclerosis of the coronary arteries, cardiovascular diseases, acute hepatitis, hemolytic anemia, bronchial asthma, severe liver or kidney disease, prostatic hyperplasia, difficulty urinating due to prostatic hypertrophy, blood diseases, deficiency of glucose-6-phosphate dehydrogenase, congenital hyperbilirubinemia (syndromes G

TeraFlu for flu and colds side effects

• Classification of the frequency of occurrence of adverse reactions:
• very often (? 1/10); often (? 1/100,
• Blood and lymphatic system disorders:
• Very rare: thrombocytopenia, agranulocytosis, leukopenia, pancytopenia.
• Immune system disorders:
• Seldom: hypersensitivity, angioedema.
• Not known: anaphylactic reaction, Stevens-Johnson syndrome, toxic epidermal necrolysis.
• Mental disorders:
• Rarely: hyperexcitability, sleep disturbance.
• Nervous system disorders:
• Often: drowsiness.
• Rarely: dizziness headache.
• Violations of the organ of vision:
• Rarely: mydriasis, paresis of accommodation, increased intraocular pressure.
• Heart disorders:
• Rare: tachycardia, palpitations.
• Vascular disorders:
• Rarely: increase blood pressure.
• Gastrointestinal disorders:
• Often: nausea, vomiting.
• Rarely: dry mouth, constipation, stomach discomfort, diarrhea.
• Liver and biliary tract disorders:
• Rarely: increased activity of liver enzymes.
• Skin and subcutaneous tissue disorders:
• Rare: rash, pruritus, erythema, urticaria.
• Kidney and urinary tract disorders:
• Rare: difficulty urinating.
• General disorders and disorders at the injection site:
• Rarely: malaise.
• If any of those specified in the instructions side effects are aggravated, or you notice any other side effects that are not listed in the instructions, inform your doctor.

Drug interactions

Effect of paracetamol Enhances the effects of MAO inhibitors, sedatives, ethanol. The risk of hepatotoxic action of paracetamol increases with the simultaneous administration of barbiturates, phenytoin, phenobarbital, carbamazepine, rifampicin, isoniazid, zidovudine and other inducers of liver microsomal enzymes. The anticoagulant properties of warfarin and other coumarins can be enhanced by long-term regular use of paracetamol, increasing the risk of bleeding. A single dose of paracetamol does not have this effect. When paracetamol is prescribed simultaneously with metoclopramide, the rate of absorption of paracetamol increases and, accordingly, its maximum concentration in plasma is reached faster. Likewise, domperidone can increase the absorption rate of paracetamol. When chloramphenicol and paracetamol are used together, the half-life of chloramphenicol may increase. Paracetamol may decrease the bioavailability of lamotrigine, with a possible decrease in its effect due to the induction of its hepatic metabolism. The absorption of paracetamol can be reduced when taken simultaneously with cholestyramine, but this can be avoided if cholestyramine is taken one hour later than paracetamol. Regular use of paracetamol with zidovudine can cause neutropenia and increase the risk of liver damage. Probenecid affects the metabolism of paracetamol. In patients taking probenecid at the same time, the dose of paracetamol should be reduced. The hepatotoxicity of paracetamol can be exacerbated by chronic or excessive alcohol consumption. Paracetamol may interfere with the uric acid test using the phosphotungstate precipitating reagent. The effect of pheniramine It is possible that the effect of other substances on the central nervous system (for example, MAO inhibitors, tricyclic antidepressants, alcohol, antiparkinsonian drugs, barbiturates, tranquilizers, and narcotic drugs). Pheniramine can inhibit the action of anticoagulants. Effects of phenylephrine TeraFlu for flu and colds is contraindicated in patients who have been taking or have taken MAO inhibitors within the past two weeks. Phenylephrine can enhance the effect of MAO inhibitors and cause a hypertensive crisis. The simultaneous use of phenylephrine with other sympathomimetic drugs or tricyclic antidepressants (eg, amitriptyline) may increase the risk of cardiovascular side effects. Phenylephrine can reduce the effectiveness of beta-blockers and other antihypertensive drugs (eg, debrisoquine, guanethidine, reserpine, methyldopa). The risk of high blood pressure and other cardiovascular side effects may be increased. The simultaneous use of phenylephrine with digoxin and other cardiac glycosides may increase the risk of developing arrhythmias or myocardial infarction. The simultaneous use of phenylephrine with ergot alkaloids (ergotamine and methysergide) may increase the risk of ergotism.

Overdose

Symptoms (mainly due to paracetamol, appear after taking more than 10-15 g): in severe cases of overdose, paracetamol has a hepatotoxic effect, including it can cause liver necrosis. Also, overdose can cause irreversible nephropathy with hepatic failure. Patients should be warned about the prohibition of the simultaneous use of paracetamol-containing drugs. The risk of poisoning is expressed, especially in elderly patients, in children, in patients with liver diseases, in cases of chronic alcoholism, in patients with chronic malnutrition and in patients taking inducers of enzyme activity. Paracetamol overdose can lead to liver failure, encephalopathy, coma and death. Symptoms of a paracetamol overdose in the first 24 hours: pallor skin, nausea, vomiting, anorexia. Stomach pain may be the first sign of liver damage and usually does not appear within 24-48 hours and sometimes may appear later, after 4-6 days, on average 72-96 hours after taking the drug. Disorders of glucose metabolism and metabolic acidosis may also occur. Even in the absence of liver damage, acute renal failure and acute tubular necrosis. Cases of cardiac arrhythmia and the development of pancreatitis have been reported. Treatment: Intravenous or oral N-acetylcysteine \u200b\u200bantidote, gastric lavage, and methionine ingestion may be beneficial for at least 48 hours after overdose. Reception is recommended activated carbonmonitoring respiration and blood circulation. If seizures develop, diazepam may be prescribed. Pheniramine maleate and phenylephrine hydrochloride Overdose symptoms include: drowsiness, followed by anxiety (especially in children), visual disturbances, rash, nausea, vomiting, headache, irritability, dizziness, insomnia, circulatory disorders, coma, seizures, changes behavior, increased blood pressure and bradycardia. With an overdose of pheniramine, cases of atropine-like "psychosis" have been reported. There is no specific antidote. Routine relief measures are required. including the appointment of activated charcoal, saline laxatives, measures to support cardiac and respiratory functions. Stimulants should not be prescribed. With hypotension, it is possible to use vasopressor drugs. In the event of an increase in blood pressure, it is possible intravenous administration alpha blockers. If seizures develop, use diazepam.

Storage conditions

• keep away from children

Information provided

Theraflu contains active ingredients (325 mg), maleate pheniramine (20 mg), phenylephrine hydrochloride (With 10 mg).

Additional elements are: citric acid, sucrose, acesulfame potassium, magnesium stearate, silicon dioxide, calcium phosphate, dyes, sodium dihydrate, maltodextrin, flavorings.

Release form

Powder for oral solution.

pharmachologic effect

Combined drug from and colds ... Effective against fever, edema, pain of various types and allergies.

Pharmacodynamics and pharmacokinetics

The medicine has analgesic, antitussive, sedative, vasoconstrictor, antipyretic, bronchodilatory, antihistamine effects, can reduce the severity of symptoms of colds and acute respiratory diseases .

Under the influence of phenylephrine hydrochloride, hyperemia of the mucous membranes of the nasopharynx, nasal cavity, paranasal sinuses, local exudative manifestations decreases, swelling decreases, the lumen of the vessels narrows.

Pheniramine maleate has antihistamine, antiserotonin, sedative, weak anticholinergic effects, is a blocker of H1-histamine receptors. Under the action of the substance, puffiness is eliminated, hyperemia of the mucous membranes , the lumen of the vessels narrows, the severity decreases, rhinorrhea, itching of the nose and eyes are suppressed.

Paracetamol is a non-narcotic analgesic, has anti-inflammatory (mild), antipyretic, analgesic effects.

Teraflu begins to act 20 minutes after taking the solution, the duration of exposure is up to 4.5 hours.

Indications for use

The medicine is prescribed for , rhinorrhea, rhinitis, colds, flu, , , vasomotor rhinitis , rhinosinusopathy .

Contraindications

Which is better than Teraflu or Coldrex?

In fact, drugs act in the same way on the body. It is important to remember that these medicines only relieve the symptoms of the disease, but do not help with treatment, and are also harmful to humans.

Also, Coldrex does not contain the antihistamine element pheniramine maleate, and the dose of paracetamol is almost twice as high, which is of course very harmful. Therefore, Teraflu is a more balanced and complex preparation.

Reviews about Teraflu

The medication effectively relieves flu symptoms and colds, however, does not eliminate the very causes of the disease. Also, the medicine is quite bad for the liver.

There are many positive reviews about Theraflu, when the drug helped in life situations in which it was necessary to feel good with a cold.

Theraflu price where to buy

The price for 1 sachet of Theraflu ranges from 30 to 50 rubles.

Packing 10 sachets costs about 370 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies of UkraineUkraine
• Internet pharmacies in KazakhstanKazakhstan

ZdravCity

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TeraFlu Theraflu for flu and colds, powder, lemon flavor, 4 sachetsFamar France

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TeraFlu Theraflu Extratab for influenza and colds, tablets, 10 pcs.Novartis Urunleri

TeraFlu Theraflu for flu and colds, powder, wild berry flavor, 10 sachetsGSK Consumer Health Inc.

Pharmacy Dialog

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Colds are usually called diseases in which the following symptoms are observed: runny nose, cough, sore throat. It is believed that colds can go away on their own, even without treatment. But it is not always the case. Certain types of colds are not easy to get rid of without medication.

What diseases are conventionally referred to as colds? By a cold, people usually mean acute respiratory viral and bacterial infections, influenza and, sometimes, cold sores on the lips.

Causes of colds

What is conducive to the disease? Why do we get colds? There are several reasons:

• Colds are generally very contagious (highly contagious);
• Weak immunity. If the immune system is not able to quickly suppress the infection, then the disease progresses rapidly;
• Hypothermia, stress - often contribute to the onset of a cold.

The main symptoms of a cold

• Fever
• Cough;
• Runny nose;
• Sore throat;
• Headache;
• Hoarse voice;
• Muscle and joint pain;
• Weakness, loss of strength;
• Redness of the eyes.

A combination of several of these symptoms is likely to indicate that you have a cold. It happens that the onset of the disease is similar to the common cold, and then additional symptoms appear:

• A rash or petechiae (small dark red spots, 1-2 millimeters in diameter) appears;
• Lymph nodes in the neck become inflamed;
• On examination, the tonsils show white patches.

These symptoms indicate that the disease can be quite serious, and, without delay, it is necessary to consult a specialist for a diagnosis and recommendations for treatment.

Cold medicine

Photo: Boiarkina Marina / Shutterstock.com

Because the course of a cold can vary, there is no one-size-fits-all cold remedy. Basically, medications are divided into two groups:

• Antiviral agents;
• Symptomatic remedies.

With a complication of ARVI by a bacterial infection, antibiotics are prescribed.

Antivirals for colds

A cold never comes on time, but there are times when you can't get sick at all and you need to get better as soon as possible. How, then, can you quickly cure a cold? Firstly, they will help to cope with a cold faster antiviral drugs... No need to wait for the disease to gain full strength, take antiviral drugs at the first sign of a cold. Good result not only in adults, but also in children, the drug "Oscillococcinum" gives. The earlier you start treatment, the faster you will see the result: the cold will go away much faster. How do antiviral drugs work for colds? On the one hand, these drugs help their own immunity to fight the infection, and on the other hand, they themselves have an effect on the virus that has entered the body.

There are a number of drugs that are targeted and are only effective against a specific type of virus. For example, this can be said about anti-influenza drugs,which include:

• Tamiflu;
• Relenza;
• Remantadin and others.

These drugs are prescribed mainly for the treatment of influenza A and B, and are ineffective for the common cold.

Interferon for colds

Sometimes, with signs of a cold, drugs containing interferon are prescribed. Interferon is a protein that the cell produces in response to the invasion of the virus in order to prevent its replication. Thus, the effect of drugs containing interferon is based on its ability to prevent the multiplication of viruses and stimulate immune system to fight viruses. Interferon-containing drugs are used to treat various viral diseases, not just colds.

Pharmacies offer a wide range of interferon-containing non-prescription drugs: drops, ointments, gels, suppositories for colds, for use in ARVI and flu. The effect of these drugs has not been proven, therefore, in Western Europe and North America, such drugs are medicines do not apply for colds.

Fever and antipyretics for colds

Photo: sirtravelalot / Shutterstock.com

The normal body temperature when measured in the armpit is 36.6 degrees Celsius. It is known that during the day the temperature can fluctuate within 0.5 - 1 degrees. With a cold, the temperature usually rises, and this is due to the fact that when microbes enter the body, they release toxins (poisons), which cause a reaction that triggers the production of specific substances, which, in turn, act on the temperature center of the brain.

In medicine, there is a special term for fever - fever. Fever always develops according to a certain scenario and has 3 stages: an increase in temperature, holding for a while elevated level, reduction to the original. Moreover, the second stage can last as long as several hours or days or a week.

Fever is a constant symptom of almost all colds.

Depending on the degree of temperature rise, fever is usually subdivided into:

• Subfebrile - 37.2 - 38.0;
• Low febrile - 38.1 - 39.0;
• High febrile - 39.1 - 40.1;
• Very high febrile (hyperpyrexia) - above 40 degrees Celsius.

Do I need to bring down the temperature for a cold?

Take your time to immediately bring down the fever, give the body the opportunity to turn on its own immunity to protect against infection. If, nevertheless, the thermometer shows a mark above 38.5 degrees Celsius, and the patient does not tolerate such a temperature well, then an antipyretic agent can be taken. Special heat dangerous for children, as it can cause seizures. Therefore, the first aid kit should always contain an antipyretic agent:

• Analgesics (paracetamol, phenazone, etc.);
• Non-steroidal anti-inflammatory drugs (acetylsalicylic acid, ibuprofen, etc.)

A brief overview of antipyretic drugs for colds:

• Paracetamol.
• Used to reduce fever in all ages.
• It is generally considered safe for children as it is not associated with the risk of Raynaud's.
• Does not irritate the stomach.
• Unlike aspirin and ibuprofen, acetaminophen does not help reduce inflammation.
• Ibuprofen.
• It has analgesic and antipyretic effects.
• In children under one year old, it should be used on prescription.
• Cannot be used in asthmatic children, chronically ill children, as well as in patients with gastritis and gastrointestinal ulcers.
• Acetylsalicylic acid.
• It is widely known under the brand name Aspirin.
• Antipyretic and anti-inflammatory agent.
• Not used in children due to the risk of Reye's syndrome.
• Not compatible with alcohol

Sore throat with a cold

With a cold, sore throat is most often associated with the following diseases:

• Pharyngitis (inflammation of the pharyngeal mucosa);
• Angina (inflammation of the tonsils and pharyngeal mucosa);
• Laryngitis (inflammation of the larynx).

Treatment for a sore throat depends on the underlying cause. For example, for sore throat, antibiotic treatment is indicated, since this disease is most often caused by bacteria: streptococci and staphylococci.

When pharyngitisappoint:

• Gargle (Miramistin, Rotokan, sage, chamomile, eucalyptus, etc.)
• Spray irrigation for a sore throat (Hexoral, Tantum Verde, etc.);
• Resorption of throat softening tablets (Gramicidin, Strepsis, Faringosept, etc.).

Cold cough

A cough is a body defense reaction aimed at removing from respiratory tract exudate, dust, foreign particles. A reflex cough occurs when the pleura is irritated. An important role in the diagnosis of cough is played by accompanying symptoms: the presence of sputum, its color and character, shortness of breath, wheezing.

Cold coughs are dry and moist. A wet cough, accompanied by the formation of phlegm, which occurs as a result of inflammation of the bronchial mucosa. For treatment wet cough with a cold you need:

• Reduce swelling and inflammation of the mucous membranes;
• Reduce the viscosity of phlegm;
• Prevent stagnation;
• Restore natural cleansing mechanisms.

Dry cough (without phlegm) requires a different approach to treatment, it is necessary:

• Relieve throat irritation;
• Reduce inflammation
• Reduce the frequency of coughing attacks;
• Convert the cough to a wet form.

The cough may persist for some time, even after all other symptoms of the disease have disappeared.

Runny nose with a cold

A runny nose or scientifically rhinitis is a common and very unpleasant symptom of a cold. Rhinitis is an inflammation of the lining of the nose. A runny nose with a cold is of a viral and bacterial nature. Nasal mucus (snot) is secreted from the nasal passages. Snot is not always a harmless symptom of a cold. Rhinitis can lead to complications of the common cold such as sinusitis, frontal sinusitis, otitis media, and some others. Therefore, the treatment of rhinitis, especially in children, must be treated carefully.

For the treatment of a common cold use:

• Vasoconstrictor drops and sprays (to facilitate breathing);
• Antibiotic drops and sprays (for bacterial infections);
• Moisturizing sprays and drops (for rinsing and moisturizing the nasal passages);
• Devices for washing the nose.

Combination drugs for the treatment of colds

There are a number of medicines that work to treat several symptoms of the common cold at the same time. Most often, the manufacturer produces such products in the form of a powder for colds. The effect of the drug is due to its constituent components. As a rule, these are:

• Vitamin C;
• Paracetamol;
• Phenylephrine, etc.

therefore combination drugs at the same time eliminate such cold symptoms as:

• Fever
• Headache;
• Chills;
• Joint and muscle pain;
• Pain in the sinuses of the nose;
• Nasal congestion;
• Sore throat.

It should be remembered that for colds and flu, it is undesirable to combine antiviral agents and combination drugs. Drink antiviral drugs first, then start treatment with combined drugs.

During a cold, try to rest more, Drink as much warm liquid as possible: tea, compote, fruit drink. Eat easily digestible food. Take medication strictly as directed by your doctor, do not self-medicate. With a cold, the most important thing is not to get a complication of the disease, remember this and take care of yourself!