What can not be mixed ask. What not to mix alcohol with

Research shows The interaction of drugs and ethyl alcohol when used together. that alcohol is dangerous to use with any drugs, as it changes their effect. However, in some cases, an adverse effect can be predicted.

Antibacterial drugs

Drinking alcohol while taking these drugs weakens or neutralizes the effect of the drugs. Alcohol in combination with certain substances can have more unpleasant consequences.

Nitrofurans and metronidazole

The enzyme alcohol dehydrogenase is responsible for the processing of alcohol in the body. Preparations of the nitrofuran group (furazolidone, nitrofurantoin, furadonin, furatsilin, furagin, nifuroxazide) and metronidazole block its production, acetaldehyde accumulates in the body - an intermediate oxidation product. This leads to a disulfiram-ethanol reaction, which manifests itself as a severe hangover.

Cephalosporins

Antibiotics of the cephalosporin group (cefazolin, cephalexin, ceftolosan) inhibit the oxidation of alcohol, prolong the state of intoxication and the toxic effects of alcohol.

Anti-tuberculosis drugs

With repeated use of alcohol, the harmful effects of drugs on the liver increase.

Analgesics

Taking aspirin, amidopyrine, analgin, butadion and other drugs of this group with alcohol can lead to drug intolerance. The combination of alcohol with paracetamol and similar antipyretics causes severe liver damage.

Means for the cardiovascular system

The combined use of nitroglycerin, validol, sustak, erinite, nitrosorbide, verapamil and alcohol leads to a sharp drop in blood pressure, combined with dizziness and nausea.

As for drugs against hypertension, in the first hours, alcohol stimulates their action due to the property of dilating blood vessels. However, then stimulation with ethanol nervous system will lead to the fact that the arterial rises even higher.

Sedative and sedative

Alcohol enhances the effect of drugs, since both alcohol and drugs depress the central nervous system. This can lead to damage to the respiratory center in the brain and cessation of breathing, cardiac arrest and death.

Insulin

Alcohol lowers blood glucose, which, when taken with insulin, which has the same effect, can lead to a hypoglycemic attack and coma. At the same time, studies show Impact of Alcohol on Glycemic Control and Insulin Action. that at risk are mainly diabetic patients who are not eating enough.

Anticoagulants

Alcohol in combination with substances that prevent blood clotting - dicoumarin, phenylin and even banal aspirin - can lead to extensive bleeding and hemorrhages in internal organs which may end in death.

2. Energy

Caffeine and other stimulants have Energy drink consumption in Europe: a review of the risks, adverse health effects, and policy options to respond. stimulating effect on the nervous system, alcohol - depressing. Together, this mixture masks the real degree of intoxication, so a person drinks more alcohol than he can afford, which increases the load on the liver and other organs.

Among the side effects of a cocktail of alcohol and energy drinks is an increase blood pressure, spasms of cerebral vessels, convulsions, stroke and heart attack.

3. Marinades

Pickled cucumbers and tomatoes - not as good as is commonly believed. Vinegar slows down the breakdown of alcohol in the body, which increases the toxic effects of ethanol on the liver and kidneys. The dehydration resulting from the slow processing of alcohol deals an additional blow to these organs.

4. Desserts and sweets

This item includes not only cakes, pastries, sweets, but also fruits and berries with a high content of simple sugars.

Alcohol has almost zero nutritional value and high energy, so the body breaks it down immediately. Sugars compete with alcohol in the queue for processing, so the breakdown of alcohol slows down, and the time of its toxic effect on the body increases. This may lead to poisoning.

Do not forget that alcohol is dangerous not only in special combinations, but also by itself. According to Alcohol consumption World Health Organization, alcohol is the cause of 5.9% of deaths in the world and 5.1% of diseases and injuries. Therefore, it is worth using alcoholic beverages with caution, even in relatively safe combinations.

Be careful if you decide to take another glass! If at the same time you use drugs, you can get a very unpredictable result!

If you are taking any of the above drugs, do not drink alcohol. Even a small dose of it can lead to devastating effects on your body.

We invite you to familiarize yourself with the most common prohibitions that are not allowed to be consumed with alcoholic beverages!

Prohibition 1. Alcohol + alcohol

1. Never mix drinks that are too different in production technology: champagne is contraindicated in “neighborhood” with vodka, whiskey and cognac; vodka "does not tolerate" the presence of beer and unaged homemade wines; Rum and brandy should not be brought face to face with liqueurs.

2. Strong spirits are risky to mix even with harmless liquids such as fruit juices, mineral water, lemonade - mixed with alcohol, they form "armor-piercing" cocktails.

3. The combination of champagne with strong drinks - vodka, cognac, rum, whiskey - is fraught with strong and quick intoxication, and then terrible hangover syndrome. Blame it all a large number of the gases it contains. It is the "funny bubbles" that contain carbon dioxide, which irritates the gastric mucosa and increases the absorption of alcohol into the blood. Any carbonated drinks mixed with alcohol act according to the same scheme, so it is undesirable to drink vodka, cognac and whiskey with mineral water and sweet carbonated drinks. A vivid example is the popular Gin-Tonic cocktail: it seems to be weak, but knocks you off your feet faster than pure vodka.

4. Mixing different kinds alcohol, it is important to remember that it is not their different strengths that are decisive, but the differences in the biological activity of drinks. Vodka, for example, for all its strength, is absorbed more slowly than natural wine. Cognac depresses the nervous system more than vodka or liquor, because it contains tannins.

5. Taking alcohol along with energy drinks is extremely life-threatening. This combination leads to a sharp increase in blood pressure, the so-called hypertensive crises. Crises can be complicated by hemorrhages in various bodies, for example, in the brain. In addition, the simultaneous use of alcohol and energy cocktails can provoke cardiac arrhythmias, seizures, impaired kidney function, and other life-threatening conditions.

Prohibition 2: Alcohol + drugs

The cause of fatal or critical consequences from alcohol is not at all the amount of alcohol consumed - the combination of alcohol with drugs is life-threatening.

What could be the threat?

Alcohol + aspirin - stomach ulcer

Alcohol + caffeine - hypertensive crisis

Alcohol + diuretics - a sharp decrease in blood pressure

Alcohol + paracetamol - toxic liver damage

Alcohol + insulin - coma

Alcohol + painkiller - intoxication

Alcohol + anti-inflammatory - intoxication

Alcohol + sleeping pills - intoxication, coma

Alcohol + antibiotics - "zero" therapeutic effect

And don't forget:

Alcohol increases the risk of breast cancer, even in moderate amounts. Alcohol also increases the risk of developing malignant tumors gastrointestinal tract, on average by 40%, compared with non-drinking people. So, try to get rid of this bad habit!

Many people safely consume alcohol during drug treatment.

At the same time, they do not at all think about the fact that they are taking drugs that are incompatible with alcohol, and about possible consequences. There are drugs that, even with the use of a small dose of alcohol, give a severe reaction to the body.

Incompatibility of drugs and alcohol: causes

First of all, it is simply illogical to correct the state of health with the help of drugs and at the same time harm the body by drinking alcohol. It is strictly forbidden to drink alcohol if you are being treated with the following groups of drugs:

  • sedatives, hypnotics, anti-inflammatory, tranquilizers;

If you drink alcohol and take pills at the same time, then alcohol will definitely change the effect of the latter. It will either reduce the effectiveness of the drug, or increase its effect on the body. In addition, alcohol can distort the effect of the drug so much that it changes its properties. In this case, it is very difficult to predict what the reaction of the body will be.

For example, if you mix alcohol with tranquilizers or sleeping pills, then such a “cocktail” will enhance the effect of drugs: very pronounced drowsiness appears, there is a violation of coordination of movements, a change in the state of consciousness. In addition, the influence of alcohol increases: a person gets even more drunk, breathing is oppressed. In extreme cases, a coma may occur;

  • antibiotics;

An extremely dangerous combination is obtained if antibiotics (especially fluoroquinolone groups) and alcohol are taken at the same time. Firstly, alcohol changes the properties and action of the drug, and secondly, it enhances their toxic effect on human body. The consequences can be sad: headache, dizziness, increased heart rate, jumps in blood pressure, suffocation, cold sweat or, conversely, fever, vomiting, nausea;

  • antihistamines.

Do not take alcohol with allergy medications, as this can lead to hallucinations, depression, or motor agitation. In addition, the state of intoxication is greatly enhanced.

Consequences of the joint use of alcohol and drugs

TO dangerous consequences leads the combination of alcohol and other groups of drugs:

  • antidepressants;

Alcohol not only neutralizes the effect of drugs, but also causes complications in the form of increased heart rate, a strong increase in pressure, up to hypertensive crisis. The danger is aggravated by the fact that this condition lasts up to 2 weeks;

  • antipyretic drugs;

If you combine alcohol and antipyretic pills, then alcohol enhances the negative effects of drugs on the liver, thereby increasing the risk of developing any inflammation or ulcers of the gastrointestinal tract;

  • diuretic drugs;

If you drink alcohol while taking diuretics (these can be pills or herbs), it can cause severe indigestion and vomiting, lower blood pressure. In extreme cases, this can lead to the development acute stage pancreatitis and even heart failure;

  • analgesics;

Alcohol and analgesics should not be consumed, as this causes a negative reaction, which is usually accompanied by headache, ringing and noise in the ears, tachycardia is observed, general state sluggish. Some people experience vomiting and nausea;

  • cardiovascular drugs;

This group includes all drugs that dilate blood vessels, as well as any other antispasmodic drugs. Alcohol tends to dilate human blood vessels, and in combination with drugs of this group, this effect increases many times over, which leads to acute vascular insufficiency. The condition is accompanied by dizziness, a sharp drop in pressure, fainting. In the most extreme case, a fatal outcome is not excluded;

  • drugs that reduce blood clotting;

Alcohol enhances the effect of drugs in this group, which can cause profuse bleeding and, as a result, hemorrhage in the vital important organs(including the brain). In the extreme case, the result of an ill-considered combination of alcohol and drugs is paralysis;

  • hormones.

Alcohol itself disrupts work endocrine system. In addition, it provokes an even greater production of certain hormones. As a result, these hormones are added to those that enter the body from the intake. hormonal drugs. As a result, the risk of developing thrombophlebitis, the appearance of a stomach ulcer (or exacerbation of an existing one), the appearance of seizures increases.

Alcohol and drugs: a dangerous combination

While it is best to stay away from alcohol when taking any medication, there are some medications that are especially dangerous when combined with alcohol. Below you can find this list and possible complications:

  • "Acetylsalicylic acid", or "Aspirin";

A “cocktail” of these two substances is very irritating to the mucosa of the gastrointestinal tract, which can lead to heartburn, exacerbation of ulcers, etc.;

  • "Analgin";

The anti-inflammatory effect that the drug carries is enhanced, but at the same time, there is a high probability of a toxic effect of the drug on the bone marrow;

  • “No-shpa” (“Drotaverin”);

On the one hand, the drug prevents the absorption of alcohol, but at the same time, the relaxing effect on smooth muscles is enhanced;

  • "Paracetamol";

This includes all tablets containing paracetamol: Panadol, Fervex, Coldrex, Citramon (and its analogues). Alcohol greatly enhances the toxic effects on the nervous system and liver of these drugs;

  • "Nolitsin", "Tsiprolet" and their analogues.

The compatibility of drugs with alcohol is absolutely excluded for the reason that the probability of depression of the central nervous system increases sharply. In extreme cases, coma is possible.

What drugs are alcohol incompatible with?

In addition to the above list, alcohol is fraught with mixing with a number of other drugs:

  • "Metronidazole" ("Trichopol");

Compatibility of drugs with alcohol leads to a hangover. The only difference is that you do not have to get drunk and wait for the next morning, because even a small dose of alcohol will be enough. In extreme cases, this combination can lead to severe intoxication, dangerous to health and life;

  • "Amitriptyline";

At best, you will pass out if you mix alcohol with this medicine. At worst, it will lead to life-threatening depression of the central nervous system;

  • "Benzohexonium";

The compatibility of the drug with alcohol is excluded due to the fact that the pressure drops sharply. It can drop to a critical point, when there is already a direct threat to human life;

  • "Diprazin", "Dimedrol";

The effect that is achieved when these drugs are combined with alcohol is familiar to many: instant intoxication, even from a small dose of alcohol;

  • "Indomethacin";

As a result of the combination of alcohol with the drug develop inflammatory processes in the gastrointestinal tract, an ulcer may appear or worsen;

  • "Ketotifen";

If you drink alcohol during the course of treatment with this drug, then the alcohol intoxication, respectively, the body gets severe poisoning;

  • "Clonidine";

When two substances are combined, there is a sharp decrease in pressure, loss of consciousness. The condition is very dangerous for human life;

  • "Levomycetin";

If you mix alcohol with pills, there is difficulty in breathing, a feeling of tightness in the chest and heat, at the same time the person is chilled, the face turns red;

  • "Tofranil", "Tavegil", "Suprastin", "Tazepam";

The combination of these antihistamines with alcohol lead to weakness, increased drowsiness;

  • "Phenazepam";

A very dangerous combination. Breathing is severely suppressed, a person may lose consciousness. In extreme cases, death is possible;

  • "Furazolidone";

If you combine this drug with alcohol, then severe poisoning awaits you;

  • "Cemetidine".

As a result, if you mix it with alcohol, you will experience severe intoxication, poisoning of the body. In addition, there is a severe headache, a feeling of heat in the body, redness of the face.

The combination of alcohol with medicines very dangerous for human health and life. Therefore, do not rush to drink alcohol if some holiday falls during your treatment, and consult your doctor. Always remember what side effects may occur otherwise. Take care of your health!

Thanks for the feedback

Comments

    Megan92 () 2 weeks ago

    Has anyone managed to save her husband from alcoholism? Mine drinks without drying up, I don’t know what to do ((I thought of getting a divorce, but I don’t want to leave the child without a father, and I feel sorry for my husband, he’s a great person when he doesn’t drink

    Daria () 2 weeks ago

    I have already tried so many things and only after reading this article, I managed to wean my husband from alcohol, now he doesn’t drink at all, even on holidays.

    Megan92 () 13 days ago

    Daria () 12 days ago

    Megan92, so I wrote in my first comment) I will duplicate it just in case - link to article.

    Sonya 10 days ago

    Isn't this a divorce? Why sell online?

    Yulek26 (Tver) 10 days ago

    Sonya, what country do you live in? They sell on the Internet, because shops and pharmacies set their markup brutal. In addition, payment is only after receipt, that is, they first looked, checked and only then paid. And now everything is sold on the Internet - from clothes to TVs and furniture.

    Editorial response 10 days ago

    Sonya, hello. This drug for the treatment of alcohol dependence is indeed not sold through the pharmacy chain and retail stores in order to avoid inflated prices. Currently, you can only order official website. Be healthy!

    Sonya 10 days ago

    Sorry, I didn't notice at first the information about the cash on delivery. Then everything is in order for sure, if the payment is upon receipt.

    Margo (Ulyanovsk) 8 days ago

    Has anyone tried folk methods to get rid of alcoholism? My father drinks, I can not influence him in any way ((

    Andrey () A week ago

It's no secret to you that mixing alcohol with pills is, to put it mildly, not the best idea?

According to a study published in the journal Alcoholism: Clinical and Experimental Research (Alcoholism: Clinical and Experimental Research). experimental studies”), 42% of people still mix them occasionally. Moreover, most often among the medications they take, they come across those that, in principle, are very dangerous to combine with alcohol: pressure pills, sleeping pills, antidepressants, muscle relaxants and painkillers.

"All of these types of pills react with alcohol, which in turn can lead to unexpected (and unpleasant) effects," said study co-author Aaron White of the National Institute of Alcohol Addiction. - For example: both painkillers and alcohol cause drowsiness and slow reaction times, severely slowing down the brain.

Together they make for a literally killer combo that can just shut him down - to the point of being fatal."

And this may be the most terrible, but, alas, not the only warning. “We must not allow the effect of alcohol and pills to sum up! Let's say if you swallow a couple of decongestant pills that constrict blood vessels and "grind" with strong alcohol, their effects will overlap, and the risk internal bleeding will increase exponentially! White warns. “Even some relatively “innocent” pills, say, for a cold, when combined with alcohol, can lead to serious consequences, such as problems with the kidneys, liver or stomach.”

What if you are taking pills, and ahead is a corporate party, inevitable like death and taxes? In other words, how to minimize the damage if you still have to drink?

“It depends a lot on how much you are going to drink and the duration of the pill,” explains the scientist. - In order to “process”, say, a glass of wine, your liver needs about an hour and a half. If at ten in the evening at dinner you plan to drink three glasses of red, and at twelve - to take sleeping pills, you are at great risk: it is likely that the effect of unremoved alcohol will add up to the effect of the pills.

And no, this does not mean that your sleep will be even stronger. Rather, on the contrary: people who interfered with sleeping pills with alcohol suffered from debilitating restless dreams and nightmares.

“The only right decision in this case would be to consult a doctor or pharmacist about the period for which the drug is excreted from the body - and“ take it on the chest ”only after it expires. In addition, be sure to read the contraindications, as well as the principle of the drug. You will see there effects similar to the effects of alcohol - watch out!

When drinking alcohol, it is necessary not only to know your norm, but also the strength of certain alcoholic beverages, the technology of their production, as well as the effect that they can have on the body when mixed. Otherwise, a fun holiday runs the risk of turning into a real hell.

Vodka + champagne or beer

Drinking champagne or beer along with vodka can result in rapid intoxication, and, consequently, loss of control over yourself and your actions, as well as a subsequent severe hangover. The fact is that champagne and beer contain carbon dioxide, which significantly reduces the time it takes for alcohol to be absorbed into the bloodstream. Getting on the gastric mucosa, the carbonated drink foams and thereby increases the rate of absorption of the liquid. Moreover, this happens not only in the stomach, but also continues in the intestines.

That is why you should not mix vodka with any carbonated drinks. Most often, the consequence of the use of these explosive mixtures is intoxication of the body, which is accompanied by headache, dizziness, nausea and apathy.

However, beer goes well with barley-based whiskey. The secret of such a tandem is simple: for the production of such whiskey, as well as for the production of beer, the same raw materials are used. That is why the ingredients of these drinks practically do not affect each other.

Wine + beer

Wine and beer are also not recommended to be consumed together. Even the old English proverb reminds of this: "Either grapes or grain." Indeed, it is the different technology for making these drinks that is the root cause of the morning hangover: wine is made from grapes, and beer is made from grain.

If you intersperse a glass of drunk wine with a glass of beer, then, most likely, you will soon begin to feel sick. And to the one who has a stronger stomach, a terrible hangover will come in the morning. The fact is that wine has an acidic reaction, therefore it irritates the gastric mucosa, helping to reduce its protective properties. And beer, saturated with carbon dioxide, only accelerates and aggravates this process.

Whiskey + cognac

Whiskey and cognac are also diametrically opposed drinks. The first is made on the basis of grain raw materials, and the second - from grape alcohol. And the strength of whiskey and cognac is somewhat different. So the strength of whiskey is 39-40 degrees, and the strength of cognac is 40-42 degrees. For alcoholic beverages, this is a significant difference. Hence the heavy hangover and gloomy morning.

Vodka + wine

Real wine is made exclusively from natural ingredients, the main of which, of course, is grapes. That is why the wine is quickly absorbed into the gastric mucosa. While vodka penetrates the blood much more slowly. Therein lies the insidiousness of this combination. Wine, being not a very strong drink, does not give such intoxication as vodka. Swapping a glass with a shot may seem like you're not getting drunk. In fact, the wine will already begin its work, and vodka will declare itself much later. And then, when both alcoholic drinks begin to act, you will quickly leave for nirvana. And the next morning, and maybe the whole next day, is unlikely to be joyful for you.

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