Candles with belladonna description. Krasavki extract rectal suppositories (suppositories) "pharmaprim

Belladonna extract has long been used to relieve muscle spasms and relieve associated pain. It has not lost its relevance to this day, and is used in modern medicines. The dosage form of suppositories is convenient for diseases of the female genital organs, hemorrhoids and in some other cases.

Rectal suppositories (suppositories) contain a thick extract of belladonna (belladonna) leaves, medicinal phenol and a suppository base. Available as candles white torpedo-shaped, which are packed in a blister. The package contains 10 candles, each suppository contains 15mg of active ingredient (belladonna leaf extract).

The product is sold in pharmacies without a prescription. average price ranges from 20 to 60 rubles, depending on the manufacturer. They are produced by several domestic and one Moldovan pharmaceutical company. You need to store the drug in the refrigerator (temperature 8 ° C), the shelf life is 2 years from the date of manufacture.

You need to open the candles immediately before use, avoiding damage to the packaging of neighboring suppositories. If the packaging is damaged and the candle comes into contact with air, it is unusable.

Healing properties

The drug is positioned as an antispasmodic and analgesic agent. Atropine and hyoscyamine, contained in belladonna, affect the vegetative nervous system... They reduce muscle tone and reduce the secretion of exocrine glands (sweat, salivary, sebaceous).

When used rectally, they relax the muscles of the rectum, gallbladder and bile ducts, relieve spasms and pain in this area. Similarly, they act on the tone of the uterus and vagina - they relax and help to avoid spasms.

The agent is poorly absorbed through the rectal mucosa, therefore it has only a local and extremely weak systemic effect. For belladonna alkaloids, a number of systemic effects on the body have been described, including dilatation of the pupil, decreased salivation, and decreased nasal discharge, but they practically do not appear when taking this dosage form.

Indications for the appointment of candles with belladonna are:

  • cracks in the anus;
  • hemorrhoids;
  • intestinal colic;
  • prevention of biliary colic;
  • hypertonicity of the uterus during pregnancy;
  • slow dilatation of the cervix during labor;
  • prostatitis and urethritis.

The medicine is for external use only. In gynecology, vaginal administration of a suppository is sometimes allowed. Although you do not need a prescription to buy, you must take the suppositories after consulting your doctor and as directed.

Instructions for use

Before using the suppository, you need to empty the intestines, wash and wipe the anus dry.

The suppository should be taken with clean hands, inserted into the rectum as deep as possible. It is best to do this while lying on your back or on your side.

The dosage of the drug and the duration of the course of treatment depend on what kind of disease the patient has. The maximum daily dose is 10 candles, but the average is 2-3.

After the introduction of the suppository, you need to lie down until it dissolves, and another 10-15 minutes to allow the active substance to be completely absorbed.

With hemorrhoids

For hemorrhoids, suppositories are used one to three times a day, depending on the severity of the condition and the chosen treatment regimen. The purpose of the drug is to anesthetize the anus, relieve rectal spasm, and reduce the risk of bleeding. When severe pain suppositories can be used without first emptying the intestines.

The duration of the course of treatment is 5-7 days, it is undesirable to prolong it - this leads to the risk of developing side effects.

Cannot be used for bleeding from hemorrhoids, necrosis of nodes - these conditions require surgical intervention.

During pregnancy before childbirth

Belladonna suppositories are used to treat hemorrhoids in pregnant women as directed by a doctor. They are also sometimes used to reduce the tone of the uterus if it is increased. But their main purpose during pregnancy is to facilitate the opening of the cervix before childbirth. If this process does not start on time, the woman is prescribed candles with belladonna - they relax the smooth muscles of the cervix and vagina.

Usually, suppositories with belladonna are prescribed a week before the expected birth for prophylactic purposes. Dosage - 2-3 candles per day, morning and evening. For greater effect, it is proposed to combine belladonna and no-shpu. If after a week the cervix does not open, the drug is canceled, delivery occurs by cesarean section.

In gynecology

The purpose of prescribing this drug for female diseases - removal of spasm of the abdominal muscles, which are accompanied primarily by adnexitis - inflammation of the ovaries.

Belladonna extract is used as part of complex therapy to relieve persistent pain, but in no case can it be used as the main remedy.

The drug is taken 2 candles a day in the morning and in the evening, in combination with other means of treating the disease. The duration of the course of treatment is individual.

Should not enter rectal suppositories vaginally - this can cause irritation of the mucous membranes and severe side effects.

For male diseases

The purpose of the drug is to relax the urethra and the muscular part of the prostate, relieve spasms and pain. The drug is indicated in complex therapy, the regimen is one candle twice a day, the duration of treatment is individual.

In urology, the drug is considered ineffective, so it is rarely prescribed. However, there are times when it is necessary to relieve pain.

Side effects and contraindications

In addition to its main action, for which it is prescribed, belladonna has a number of side effects, most of which are undesirable. The use of a large single dose or too long treatment causes not only local, but also systemic effects.

As with any candles, irritation and itching may occur in the area of \u200b\u200bdrug administration, and in addition:

  • intestinal atony and constipation;
  • retention of urine;
  • dry mouth, impaired swallowing;
  • dilated pupils, dry eyes;
  • dizziness, feeling of heat;
  • tachycardia, arrhythmia.

Long-term use of candles with belladonna makes such symptoms persistent, it is rather difficult to cope with them even after the drug is discontinued.

Overdose is manifested by acute urinary retention, pain in the heart, nausea and vomiting, dry mouth up to the inability to speak, a sharply dilated pupil.

Treatment is symptomatic, in case of serious condition, hospitalization is necessary.

Candles cannot be used when:

  • glaucoma and suspected glaucoma;
  • heart rhythm disorders;
  • hypersensitivity to the drug;
  • intestinal atony, constipation;
  • severe atherosclerosis;
  • ulcerative colitis with a risk of bleeding;
  • intestinal obstruction of any genesis.

Interaction with other medicinal products should be discussed with your doctor. The instructions indicate the main points regarding this issue, so you need to carefully study it.

This tool should not be used when oncological diseases rectum and genitals, as well as suspicion of them. Therefore, with hyperplasia of the prostate gland, suppositories with belladonna are not prescribed.

What can be replaced

There are remedies with the same effect. Among them are candles Bekarbon, Betion, Hemorol and Anusol - they also contain belladonna extract and are used for hemorrhoids and some other conditions.

Other forms of release

Belladonna extract is available as a stand-alone dosage form, and is also included in various medications. Most often, it is combined with anesthetic substances, such as in the composition of Belalgin.

The indications for the use of each dosage form are different. The tablets are used for abdominal pain, pain in muscles and joints, with spasms of smooth muscles. The ointment is applied to the affected area - most often, spasmodic muscles.

Composition and release form of the drug

5 pieces. - contour cell packages (2) - cardboard packs.

pharmachologic effect

Means vegetable origin... Contains alkaloids, hyoscyamine, scopolamine, which have m-cholinolytic activity. Blocks m-cholinergic receptors and prevents the interaction of acetylcholine, a mediator with them parasympathetic department the autonomic nervous system. Reduces the secretion of the digestive, bronchial, lacrimal, sweat glands. Relaxes smooth muscles and causes spasm of the sphincters of the intestines, bile and urinary tract, has a bronchodilator effect, mainly on small bronchi and bronchioles. Causes pupil dilation and accommodation paralysis, increases intraocular pressure. Reduces cholinergic effects vagus nerve on the heart. As a result of the predominance of adrenergic (sympathetic) influence on the heart, tachycardia occurs, and AV conduction improves. The blood vessels and blood pressure are practically not affected.

The duration of the resorptive action of alkaloids ranges from 2 to 6 hours. local application on the mucous membrane of the eyes, accommodation is disturbed for 3-4 days, mydriasis persists up to 7-10 days.

In high doses, it has a stimulating effect on the cerebral cortex, causes motor and speech excitement, hallucinations, activates, and with an increase in the dose, depresses the respiratory center.

Indications

For systemic use: spasms of smooth muscle organs of the gastrointestinal tract, bile and urinary tract, hypersecretory gastritis, peptic ulcer stomach and duodenum, pancreatitis, hypersalivation, poisoning with salts of heavy metals, m-cholinomimetics, anticholinesterase agents, obstructive bronchitis, premedication before surgical interventions, bradyarrhythmias, AV blockade, prevention of cardiac arrest and bronchospasm during anesthesia.

For topical use in ophthalmology: for the study of the fundus, for the treatment of iritis, iridocyclitis, choroiditis, keratitis, embolism and spasm of the central retinal artery, some.

Contraindications

Glaucoma, suspected glaucoma, stenosing gastrointestinal diseases, intestinal atony, acute ulcerative colitis, mechanical intestinal obstruction, atonic constipation, benign hyperplasia prostate gland, pronounced atherosclerosis, acute pulmonary edema, cardiac decompensation, tachyarrhythmia, acute bleeding, myasthenia gravis, lactation, hypersensitivity to belladonna.

Dosage

Individual. The dose, frequency and duration of use depend on the indications, the patient's age and the dosage form used.

Side effects

For systemic use: possible nervousness, drowsiness, weakness, dizziness, sleep disorders, ataxia, speech impairment, agitation (especially in elderly patients), dry mouth, loss of taste, loss of appetite, constipation.

In case of overdose: nausea, vomiting, tachycardia, tachyarrhythmia, myocardial ischemia, impotence, suppression of lactation, idiosyncrasy, urticaria, decreased sweating, hyperthermia.

When applied topically: visual impairment, mydriasis, accommodation paralysis, increased intraocular pressure, photophobia.

Drug interactions

Krasavka reduces or eliminates the effect of m-cholinomimetics, anticholinesterase agents.

It potentiates the arrhythmogenic effect of MAO inhibitors, cardiac glycosides, clonidine, cholinolytic properties of quinidine, novocainamide, the effects of barbiturates, adrenomimetics, antihistamines, tranquilizers.

With lead acetate, calcium salts, tannin, forms a precipitate.

special instructions

Use with caution in patients with polyneuropathy, hyperthyroidism, coronary artery disease, chronic heart failure, hypertension, kidney disease, diaphragmatic hernia, reflux esophagitis. Not recommended long-term use at gallstone disease and nephrolithiasis.

When high temperature environmental application of belladonna may result in.

Influence on the ability to drive vehicles and use mechanisms

Pregnancy and lactation

The use of belladonna during pregnancy is possible only if the intended benefit to the mother outweighs the potential risk to the fetus.

During lactation (breastfeeding), the use of belladonna is contraindicated.

With impaired renal function

Use with caution in patients with kidney disease.

Candles with belladonna - an effective, inexpensive drug for intestinal colic and spasms. It is a natural alkaloid capable of providing a rapid antispasmodic, analgesic, antipyretic effect.

In permissible dosages, the drug is harmless, it is often prescribed to pregnant women in the prenatal period with excessive tone of the uterine cavity, also to children, intestinal colic.

Contraindications and side effects are minimal, however, in order to avoid harming the body, it is important to read the instructions before use, observe the dosages, the timing of the treatment course.

Belladonna and its effect on the body

Belladonna vulgaris is considered a poisonous plant. Contains: alkaloids (atropine, hyoscyamine). When taken in large doses, it can cause rabies, inappropriate behavior in people due to an active effect on the psyche, the autonomic system.

If you do not neglect dosages, take in small quantities (in moderation), then the drug is quickly capable of:

  • quickly normalize blood circulation in the anus;
  • accelerate the processes of tissue regeneration, rectal mucosa;
  • eliminate spasms in the muscle sphincter;
  • normalize the function of the sebaceous glands;
  • block cholinergic receptors.

A similar effect is observed due to the rapid penetration, absorption active substances candles with belladonna through the integument of the skin, exerting an active influence on the affected areas.

Belladonna suppositories in the form of suppositories lead to:

  • weakening of smooth muscle muscles;
  • rapid absorption into the bloodstream immediately after administration into the rectum;
  • relieving spasm, inflammation of smooth muscle muscles;
  • stimulation of the heart;
  • normalization of urination;
  • suppression of the secretion of the digestive glands;
  • providing an antiseptic, analgesic effect.

Mechanism of action and composition

Belladonna extract is produced in pharmacology in the form of yellow torpedo-shaped candles.

The composition includes active components:

  • atropine;
  • hyoscyamine;
  • belladonna extract.

Additional ingredients:

  • zinc salts;
  • xeroform (astringent, drying agent);
  • phenol;
  • ichthyol with anti-inflammatory effect.

Attention! Before using candles, it is better to first consult with a specialist. It is important to take into account the individual characteristics, symptoms, features of the ongoing disease, in the treatment of which belladonna extract will be applicable.

The main purpose of candles with belladonna is with rectal use to suppress unpleasant symptoms: pain, spasms, itching, burning sensation in the rectal area.

The drug will help to quickly relieve swelling and inflammation, stop the action of negative acetylcholine by interacting with receptors. As a result, the action of acetylcholine is suppressed, the susceptibility of cells to pain in the perianal folds at the time of transmission to nerve impulses decreases.

The drug is fast absorbed, therefore, it perfectly penetrates the vessels and tissues of the rectum, blocks spasms in the anus, reduces swelling.

Indications for use

Candles with belladonna are an antihemorrhoidal agent.

It is often prescribed in gastroenterology, gynecology, proctology in the treatment of the following diseases:

The drug is indicated for use by women in the prenatal period to relieve abdominal cramps, soften the cervix, and stimulate contractions. In particular, as with inflammation of the appendages, painful periods.

  • hormonal disorders;
  • diseases and processes with an infectious, inflammatory course (adnexitis, salpingitis, endometritis, dysmenorrhea, ovarian cysts, fibroids, endometrial hyperplasia, adhesions), negative manifestations after removal of a polyp in the uterus;
  • painful periods.

Attention! It is not recommended to use belladonna with strong uterine bleeding... Application can only provoke increased bleeding. Especially if there is additionally a hormonal imbalance in the female body.

Contraindications to use

Belladonna suppositories can have a fairly strong laxative effect and can lead to dehydration.

In particular, for children under 14 years old, rectal suppositories can lead not only to a strong weakening of the muscle muscles, but also to negativity for the body as a whole.

Side effects

An undesirable effect after using candles with belladonna is observed due to the active effect of substances on the muscles and secretory glands.

If the permissible doses are exceeded, poisoning is possible, the appearance of side effects:

  • increased heart rate, pulse;
  • decreased vision;
  • excessive dilation of the pupils;
  • migraine;
  • convulsive syndrome;
  • dry and sore mouth;
  • feeling of thirst;
  • allergies, itchy skin;
  • tachycardia;
  • dizziness.

Instructions for use

The drug is indicated in the treatment of many pathologies to relieve inflammation, pronounced discomfort in the gastrointestinal tract and intestines, and provide an antispasmodic, analgesic effect.

Step-by-step instructions for using rectal suppositories:

The prescribing of the drug is exclusively carried out by the attending specialist, in particular, it determines the doses and duration of the course.

It is not necessary to have a bowel movement, if you need to enter only 1 candle to eliminate pain. A single dose is often prescribed for women with painful periods in order to relieve pain immediately before the onset of menstruation.

Self-medication can have serious consequences. If appeared side effects after using candles with belladonna, you should immediately postpone the drug and consult your doctor.

With hemorrhoids

The main purpose of rectal suppositories with belladonna is, the healing of microcracks in the anus.

The drug promotes:

  • stopping the infectious process;
  • removal of puffiness, burning;
  • weakening of the sphincter and smooth muscles;
  • facilitating the act of defecation;
  • resorption of hemorrhoidal sacs with blood stasis;
  • healing cracks.

It is prescribed for pregnant women in the prenatal period to weaken the intestinal sphincter and for prevention in order to avoid the development of hemorrhoids.

The main course of treatment is 5-7 days with 3-fold administration of 1 suppository per day. It is advisable to use the drug after going to the toilet and completely emptying the intestines. For the purpose of instant and one-time pain relief, it is not necessary to empty the intestines.

On a note! First, you need to carry out hygienic measures and only then open the contour packaging, remove the candle. It is undesirable for it to melt in your hands, so you need to immediately inject it into the rectum as deeply as possible, do not jump out of bed right away, but wait 30-40 minutes.

If the pain is severe, then it is possible to increase the dose to 10 pieces per day. The optimal dosage is 3 suppositories. The course of treatment is 1 week. Taking into account the degree of development of the disease, it can be extended up to 10 days.

Important! Do not take the drug in unlimited quantities. This is the strongest alkaloid and can lead to intoxication of the body. In particular, belladonna extract has side effects, contraindications, so it is better to consult a doctor before using it in the treatment of hemorrhoids.

Application in gynecology

Traditional healers have always used a natural alkaloid in the treatment of many female diseases.

Belladonna suppositories treat painful menstruation, have a calming effect on the nervous system, suppress nervousness and irritability in women on critical days.

This is an excellent natural antiseptic that can help before childbirth, have an antispasmodic effect.

It is the candles with belladonna that will help in the treatment of female pathologies:

  • adnexitis;
  • inflammation of the appendages;
  • cervical erosion;
  • dysmenorrhea in order to relieve painful syndrome;
  • endometriosis.

The drug helps to weaken the muscles of the cervix, so often doctors prescribe in the prenatal period in order to prevent the development of hemorrhoids.

Attention! Candles with belladonna should be used carefully by women in the third trimester of pregnancy, taking into account the general well-being, the existing symptoms.

For male diseases

The drug in the form of suppositories is often prescribed to men with an inflammatory course in the prostate gland, an infectious course of certain pathologies. Often candles with belladonna are prescribed in combination with other drugs to eliminate signs of prostatitis.

Reference! Candles should not be used lightly. They cannot be used for oncology, other serious internal diseases in men.

Application during pregnancy and before childbirth

During pregnancy, candles are prescribed to women vaginally in order to soften and weaken the cervix, which is important before childbirth.

Although it is undesirable to take candles on your own in order to avoid deterioration in general well-being.

Candles with belladonna are not applicable for diseases in pregnant women:

  • hyperthyroidism;
  • hypertension;
  • renal failure.

If side effects are observed, then you need to urgently remove the candle from the vagina and consult a doctor for advice. It is important to understand that belladonna is a poisonous plant and can cause nausea, vomiting, confusion, and tachycardia.

If you take the drug in acceptable doses, then this will contribute to:

  • increasing tissue elasticity;
  • facilitating the passage of the generic process;
  • rapid delivery;
  • elimination of painful symptoms.

To achieve a quick effect, candles can be used in combination with No-shpa. The recommended dose for pregnant women is no more than 3 suppositories per day.

Attention! You can not neglect the courses of treatment and use belladonna for a long time in the early stages of pregnancy. This can provoke a miscarriage, have a negative effect on the fetus. It is extremely important for women to take into account any body reactions to this drug. The use of belladonna suppositories should be carried out under the full supervision of a doctor with monitoring of possible risks.

The frequency of use of suppositories per day is prescribed for women exclusively by the attending physician, since even small doses can lead to an overdose. It is not recommended to use the drug vaginally with severe bleeding or extensive cracks in the rectum.

When using the drug in the heat, signs of allergy such as hives on the body or heatstroke may appear.

Belladonna suppositories contribute to the inhibition of the nervous system and can lead to a decrease in concentration. It is not advisable to drive a car during the period of treatment.

Long-term use can provoke premature birth. It happens that suppositories lead to a strong weakening of the sphincter and persistent diarrhea, This is fraught with dehydration.

Women during pregnancy need to be more vigilant and be wary of any medications, even those containing natural ingredients. The appearance of any negative manifestations after the use of belladonna should be a reason for contacting a gynecologist.

Important! It is contraindicated to take candles with belladonna for women while breastfeeding. But in late pregnancy, in order to prevent the development of hemorrhoids, it is possible to prescribe the drug immediately before childbirth. If, of course, the benefit is maximum compared to possible risks for the kid.

Often, suppositories are prescribed for women in the postnatal period to restore uterine functions, reducing discomfort during the primary appearance of hemorrhoidal cones, which often happens against the background of complicated labor.

However, the use of candles is permissible only when artificially feeding a baby due to possible penetration into breast milk plant components of poisonous belladonna.

The benefits and harms of candles

In order to restore the walls of the anus, suppositories are often prescribed in the postoperative period.

The plant extract contains not only belladonna, but also phenol with a laxative effect.

When using belladonna candles, it is additionally recommended to adhere to a diet, avoid constipation and include foods high in fiber in the diet.

The drug has proven effective in treating cracks and fistulas in the anus, external and internal residual hemorrhoids.

The benefits of the drug:

  • withdrawal pain with menstruation in women on critical days;
  • calming the nervous system, relieving overexcitation;
  • relaxation of the smooth muscles of the uterus before childbirth.

However, it is undesirable to take it without consulting a doctor. Belladonna suppositories are a medicine containing the poisonous plant Belladonna and phenol content.

Overdose can lead to rather unpleasant manifestations:

  • the threat of miscarriage in the 1st trimester;
  • premature birth in the 3rd trimester;
  • signs of diarrhea, dehydration;
  • increased heart rate;
  • dizziness;
  • headache;
  • dryness, perspiration, thirst in the mouth.

It is important to monitor the action of the candles. At the slightest unpleasant manifestations, inform the doctor.

Which drug to choose?

The choice of suppositories should completely depend on the degree of progression of the inflammatory process in the intestine, symptoms and main manifestations of hemorrhoids. In case of infection with an infection, it is better to use suppositories with phenol to relieve swelling and inflammation.

With an inflammatory course, damage to the intestinal mucosa, ideally, choose suppositories - Betiol, with pain in the anus, rectum - Anusol.

Consider candles with belladonna:

  1. , contains zinc sulfate, tribromophenol, bismuth belladonna extract. The drug has an antispasmodic, antiseptic, astringent, antipruritic effect. Efficiency is observed within 20 minutes from the moment the suppository is inserted into the anal passage. The duration of the effect is up to 6 hours. The recommended dose for use is 3 suppositories per day. Price - 120 RUB for 10 pieces.
  2. Belladonna extract to relieve abdominal cramps, provide an analgesic and antiseptic effect, relieve inflammation in complex lesions of the rectum with an infection, increase the muscle tone of the cavity in the peritoneum. Price - RUB 55-75 for 1 package.
  3. Betiol, suppositories containing ichthyol, belladonna extract to relieve inflammation, relieve pain, unpleasant manifestations in the rectum. Ichthyol extract will help eliminate spasms, soreness, swelling in the rectum, does not lead to side effects. It is quite effective, safe drug destruction of foci of inflammation in the rectum. Cost - 60-75 rubles.

Attention! If it is not known which drug is best to resort to for discomfort in the anus, it is better to first consult a doctor. To achieve a greater effect, it is important to calculate the doses, adequately assess the degree of development of the disease and overall well-being.

;
  • Posterized.
  • Let's consider some of them in more detail:

    • Papaverine - excellent antispasmodic, helps to reduce tone smooth muscle gallbladder, secretion of gastric, bronchial and sweat glands. It is indicated in the treatment of stomach ulcers, duodenal ulcers, gastritis, biliary colic. Acceptable dose - up to 3 times a day. Children under 2 years old - 0.5 tablets. For adults, reception is possible in combination with nicotinic acid, phenobarbital. The composition contains ethanol, so the safety of the drug during pregnancy and lactation has not been established. It should be taken with caution when driving.
    • Belladonna - a poisonous plant, therefore it is important to observe the dosage when applied, take into account the existing contraindications. If there are side effects, then you should immediately inform the doctors, stop using.

    The duration of the resorption of alkaloids is up to 6 hours. Excess doses when ingested can contribute to strong stimulation of the cerebral cortex, lead to speech arousal, hallucinations, suppression of the respiratory center.

    Also, when using analogs of candles with belladonna, it is better to first consult with a doctor, because it is not known how medicines with a similar composition will affect the body as a whole.

    Candles with belladonna - safe and effective drug when used in dosage form. You can use women during the period of a woman during pregnancy if delicate problems arise.

    However, it is important to consider contraindications, side effects in order to avoid complications. Although many patients and doctors speak only positively about this drug.

    Latin name:Belladonna extract
    ATX code: A03BA04
    Active substance: Belladonna leaf extract
    Manufacturer:Biosynthesis, Russia
    Pharmacy leave: Without recipe
    Storage conditions:from 15 to 25 C
    Shelf life:24 months

    The phytopreparation is the strongest antispasmodic. Applying belladonna extract, it is possible to stop pain syndrome, normalize the gastrointestinal tract (tablets), eliminate manifestations of bradycardia (tincture), speed up the healing process and relieve inflammation in hemorrhoids (suppositories).

    Indications for use

    Tablets are used to eliminate the manifestations of gastrointestinal ulcers and relieve epigastric pain.

    The tincture is used as an analgesic and antispasmodic agent for ulcerative pathologies of the gastrointestinal tract, gallstone disease, as well as other ailments that are characterized by spasms of smooth muscles abdominal cavity... The drug is used for bradycardia, which is associated with the excitation of the vagus nerve.

    Suppositories are used to treat such proctological pathologies as hemorrhoids, promote wound healing and regeneration of mucous membranes.

    Composition and release forms

    Tincture of belladonna leaves at 40% ethyl alcohol (1:10), includes alkaloids - 0.027-0.033%. A dark brown solution with a pronounced alcohol smell in 10 ml vials is realized.

    The tablets include three phytoextracts - belladonna, wormwood and valerian in an amount of 0.01 g; 0.012 g; 0.015 g, respectively. Tablets (for oral administration gastric) with cream-colored belladonna extract, round, placed in a blister of 10 pcs. There is 1 blister inside the pack.

    Krasavki extract in the form of rectal suppositories contains a thick phytocomponent (1:10) with a mass fraction of 15 mg. Additionally, phenol is present. Candles with belladonna extract (used for hemorrhoids), light yellow, are packaged in contour packs of 5 pcs., 10 soup is placed inside the pack.

    Healing properties

    The herbal remedy exhibits an m-anticholinergic effect, helps to eliminate spasm. Prevents the stimulating effect of acetylcholine itself, while significantly reducing the secretion of a number of glands (lacrimal, salivary, sweat, stomach, and bronchial), partially inhibits the exocrine activity of the pancreas. The action of the drug is aimed at relaxing the muscles of the gastrointestinal tract, reducing the tone of the gallbladder, as well as bile ducts, while it has a tonic effect on the sphincters. Against the background of admission, tachycardia may develop, AV conductivity increases significantly. Phyto-drug promotes dilation of pupils, the development of intraocular hypertension, accommodation paralysis is possible.

    During rectal use, the phytoextract interacts with receptors, which are located in the smooth muscles of the rectum, as a result of this, a decrease in tone and elimination of spasm is recorded, relief of painful sensations provoked by an increase in hemorrhoids and cracks. Slight systemic absorption is possible during rectal use.

    Krasavki extract: instructions for use

    Tincture for adults is prescribed in a dosage of 5-10 drops, for children, 1-5 drops are indicated. LS. The largest single dosage for adults is 23 caps, the boundary daily dose is 70 caps.

    Pills will need to be used 1 pc. twice or thrice throughout the day.

    Contraindications and precautions

    Price: from 39 to 53 rubles.

    It is contraindicated to use tincture and pills when diagnosing intraocular hypertension, increased susceptibility to phytoextracts. The drug is not prescribed for children.

    The use of suppositories is not recommended for persons with pathological prostatic hyperplasia and deterioration of urine outflow, with the development of glaucoma. During treatment with a drug in the form of candles, you should be careful when driving a car and working with precise mechanisms.

    Cross-drug interactions

    The alkaloids contained in the phytoextract reduce therapeutic effect from the use of ketoconazole, anticholinesterase drugs, m-cholinomimetics, drugs with anticoagulant properties, corticotropin. In the case of the simultaneous use of drugs for the introduction of anesthesia, the duration of their action is reduced.

    The drug based on belladonna extract increases the therapeutic effect of taking anticholinergic drugs, antidepressants.

    The phytopreparation is incompatible with thiamine bromide, chlorpromazine, proserin, caffeine-containing agents, diprazine, pilocarpine.

    Before using any other medicines, you will need to consult a specialist.

    Side effects and overdose

    While taking tinctures and tablets, you may feel dryness of the mucous membranes oral cavity, deterioration of visual perception, tachycardia attacks.

    When using rectal suppositories, signs of intestinal atony, urinary retention, severe dizziness may appear.

    In the event of any negative symptomatology, it is recommended to complete treatment with a phytopreparation and consult a doctor. If necessary, the specialist will prescribe an alternative treatment that is better tolerated.

    Analogs

    Nizhpharm, Russia

    Price from 59 to 81 rubles.

    The drug is intended for rectal use. Betiol allows you to eliminate local discomfort, pain, and spasm. The main component is represented by an extract from belladonna leaves. The drug is prescribed for hemorrhoids, anal fissures. Usually, the treatment regimen involves the use of candles three times throughout the day, 1 pc. The treatment is carried out for 10 days.

    Pros:

    • Low price
    • There are practically no contraindications for use
    • High efficiency in the treatment of hemorrhoids.

    Minuses:

    • Constipation may occur during use
    • Contraindicated for use in prostate adenoma
    • In case of an overdose, convulsions may occur.

    Biosynthesis, Russia

    Price from 75 to 98 rubles.

    The tool is characterized by an antiseptic effect, eliminates inflammatory process, spasm, slightly dries the mucous membranes, which provides fast healing... It is prescribed with an increase in hemorrhoids, anal fissures. In addition to the extract of belladonna leaves, there is bismuth tribromophenolate and zinc sulfate. The drug is available in the form of suppositories.

    Pros:

    • Can be used in case of damage to the anorectal area
    • Quickly removes irritation
    • Availability.

    Minuses:

    • Contraindicated in angle-closure glaucoma
    • May provoke sleep disturbance
    • In case of an overdose, hyperthermia is possible.

    Belladonna extract
    Instructions for medical use - RU No. R N000580 / 01-2001

    Last modified date: 15.06.2017

    Dosage form

    Rectal suppositories

    Composition

    1 suppository contains:

    Active substance : belladonna extract thick (containing the sum of belladonna alkaloids in terms of hyoscyamine 1.5% - 0.225 mg) - 15 mg;

    Excipients: phenol, water, a mixture of macrogols (macrogol 1500 - 98%, macrogol 400 - 2%).

    Description of the dosage form

    Suppositories from white with a yellowish tinge to light brown, torpedo-shaped. Marbling is allowed.

    Pharmacological group

    Herbal antispasmodic

    Pharmacodynamics

    The pharmacological action of the drug is due to the complex of alkaloids that make up the belladonna extract (hyoscyamine, scopolamine, atropine). The drug has an antispasmodic, analgesic effect.

    Pharmacokinetics

    No data.

    Indications

    Hemorrhoids, anal fissures.

    Contraindications

    Hypersensitivity to the components of the drug, angle-closure glaucoma, prostatic hypertrophy with impaired urine outflow, obstructive diseases of the gastrointestinal tract, intestinal atony, active ulcerative colitis, chronic heart failure in the stage of decompensation, tachycardia, myasthenia gravis, pregnancy, breastfeeding period, childhood under 18 years old.

    Carefully

    Autonomic neuropathy, hyperthyroidism, ischemic disease heart failure, chronic heart failure, mitral stenosis, kidney disease, hiatal hernia, reflux esophagitis, increased body temperature (the likelihood of developing fever and heatstroke due to suppression of the activity of sweat glands).

    Application during pregnancy and lactation

    The use of the drug during pregnancy and during breastfeeding is contraindicated. If necessary, use the drug during lactation breast-feeding should stop.

    Method of administration and dosage

    Rectally, after a cleansing enema or self-emptying of the intestines. 1 suppository 2-3 times a day, the maximum daily dose is 10 suppositories. Usually the duration of the course of treatment is 7-10 days.

    Before use, the suppository should be removed from the blister strip packaging.

    Side effects

    Possible allergic reactions, dry mouth, thirst, constipation, tachycardia, mydriasis, paresis of accommodation, dizziness, photophobia, urinary retention.

    Overdose

    Symptoms: dryness of the mucous membrane of the mouth and nose, thirst, constipation, tachycardia, mydriasis, paresis of accommodation, dizziness, photophobia, decreased sweating, urinary retention; in more severe cases - psychomotor agitation, convulsions, acute urinary retention. In case of overdose, the drug should be discontinued and a doctor should be consulted.

    Treatment: symptomatic and supportive therapy.

    Interaction

    With simultaneous use with tricyclic antidepressants, it is possible to enhance the m-anticholinergic effects of the drug (dry mouth, impaired accommodation, tachycardia, constipation, etc.). When used with drugs that increase the heart rate (including procainamide), severe tachycardia is possible. MAO inhibitors increase the risk of side effects and enhance the positive chrono- and batmotropic effect; when used together with cardiac glycosides - strengthening the positive batmotropic effect... With the simultaneous administration of ethanol (alcohol) with belladonna preparations (belladonna), an increase in the inhibitory effect on the central nervous system (CNS) is possible.

    special instructions

    Consideration should be given to the possible penetration of belladonna alkaloids through the blood-brain barrier and possible interaction with medicinesaffecting the central nervous system.

    IN therapeutic doses belladonna alkaloids have a moderate stimulating effect on the central nervous system, in large doses - an exciting effect, in toxic doses - agitation, hallucinations, followed by inhibition and coma.

    Simultaneous administration of suppositories with belladonna extract and other drugs with anticholinergic activity should be avoided, since the likelihood of side effects increases.

    Krasavki extract helps to reduce the rate of absorption of jointly used drugs and other drugs due to inhibition motor function gastrointestinal tract.

    Impact on the ability to manage vehicles, mechanisms

    During the treatment period, care must be taken when driving and engaging in other potentially dangerous species activities requiring increased concentration of attention, speed of psychomotor reactions and good vision.

    Release form

    Rectal suppositories 15 mg.

    5 suppositories are placed in a blister made of polyvinyl chloride film laminated with polyethylene.

    Two blister packs with instructions for use medicinal product placed in a pack of cardboard.

    Storage conditions

    At a temperature not higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life

    Do not use the drug after the expiration date.

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