The duration of the action of paracetamol. Preparation "Paracetamol": action, description, features of application and reviews Spending paracetamol

Instructions for use:

Paracetamol is an anesthetic and antipyretic agent from the NSAID group (non-steroidal anti-inflammatory funds), non-marketal analgesic. The World Health Organization is included in the list of the most important medicines.

pharmachologic effect

The active substance of the drug is paracetamol, a derivative of a fenacetin. The mechanism of action of paracetamol is based on the oppression of the synthesis of prostaglandins - chemical compounds formed during inflammation, and responsible for its signs in the form of a rise in temperature and appearance of pain. The analgesic effect paracetamol has, affecting the neurons of the central nervous system. It has a weak anti-inflammatory effect, does not irritate the mucous membrane of the gastrointestinal tract.

When entering the body, the drug is absorbed into the blood, from there is spread over all the tissues of the body. Destruction occurs in the liver, with the formation of intermediate products of metabolites - some of which (para-aminophenol) are toxic. This fact limits the use of paracetamol with liver and blood diseases. In the future, metabolites pass through the renal filters and are removed with urine, and therefore, with impaired kidney function, the use of paracetamol is also undesirable.

With oral administration, paracetamol reaches the maximum concentration in the blood 20-30 minutes after the reception, after an hour and a half the peak of the drug is coming.

Forms of release

Paracetamol is produced in the following forms:

  • Tablets for oral application, with an existing substance of 200 and 500mg;
  • Pills for oral administration coated with shell (capsules), 500mg paracetamol in each;
  • Swiming tablets for the preparation of the solution, 500mg of the active substance in one tablet;
  • Solution for infusions, 15mg in 1 ml solution, ampoules of 5 ml;
  • Syrup for children, 200mg paracetamol in 5ml solution;
  • Suspension for children, 120mg in 5 ml solution;
  • Rectal suppositories with a dosage of the active substance from 50mg (for children) to 1000mg.

Paracetamol - one of the most famous and widely used drugs in the world, the same active ingredient is produced by various pharmaceutical companies under various trademarks: Abestanil, Akamoltev, Aktazol, Alvedon, Acetopen, Algotatol, Ampaodol, Aminophen, Amphenol, Apamid, Apamid, Atanol, Acelifene, Acetsol, Acetalgin, Acetaminophen, Acetaminophenol, Biocetamol, Bindard, Valgarian, Valorin, Valghezik, Vanitol, Volpan, Dapirecks, Datril, Dafalgan, Dexamol, Deminophen, Dimindol, Damin, Dolax, Dolipram, Iphimol, Calpol, Mexalen, Metamol, Minoset, Malgin, Napatopola, Naprinol, Nizaitztol, NEPA, Opradol, Panadol, Panadol Salub, Panadol Junior, Paramol, Paramol, Pyramol, Pironazin, Rollycin, Tilenol, Temperamol, Tilelight, Tilemin, Talgon, Ushamol, Febdol, Febrinyl, Febrinol, febriste, fendon, chemcetafen, celifun, cetadol, cetanyl, Effergangan, Efferer, Erotoketamol.

Indications for the use of paracetamol

Indication to paracetamol is the body temperature, elevated to subfebrile and febrile values \u200b\u200b(37 - 39 ° C) with various diseases of infectious and inflammatory origin. In pediatric practice, testimony to paracetamol are pain in the gums and fever caused by teething.

According to the instructions, paracetamol is effective as a means for removing pain syndrome of various origin: Headache, Malgy, Arthrelgia, Algodismenorrhea, Radiculitis, Ishias, Neuralgia, Toothpro and wandering pain of unclear etiology.

Attention! When applying this drug to remove acute pain, it can significantly reduce the symptoms, in connection with which it will change clinical picture Diagnosis may be difficult.

Paracetamol instructions

The one-time dosage of paracetamol according to the instructions is from 500 to 1000mg for adults and children over 12 years old, the daily dosage for this group should not exceed 4g (4000mg) of the medicinal substance.

Dose of the drug for children's age calculated individually, depending on the weight of the child, at the rate of an average of 125-250mg of the active substance for one reception, regardless of dosage form. Regardless of the form medicinal preparationThe daily dose must be distributed on 3-4 receptions, with a time interval between them at least 4 hours.

In accordance with the instructions, paracetamol should not be used over 3 days without medical control. If during this time the symptoms of the disease did not receive reverse development, it is necessary to refer to the doctor about the possibility of further use of the drug and its dosage.

Side effects

Under the instructions, paracetamol is one of the safest preparations whose side effects are extremely rare. Nevertheless, they are described in the medical literature, and are usually associated with increased individual sensitivity or with the presence of a hidden concomitant pathology.

The side effects associated with the reception of paracetamol include:

  • From side digestive system - development of liver dysfunctions, the appearance of signs of dyspepsia;
  • From the blood of blood - anemia, methemoglobinemia, deterioration of blood pattern (thrombocytopenia, agranulocytosis, leukopenia, etc.);
  • From the cardiovascular system - changes in cardiac conductivity (intracardiac blockades);
  • From side immune system - allergic reactions of various intensity, more often than a slow type, less often immediate (anaphylactic shock);
  • From the urinary organs - the development of interstitial nephritis, polyuria and other impaired renal function.

A number of specialists argue that there are data on the development of bronchial asthma in a significant number of children who took paracetamol (41%). Despite the fact that this point of view is controversial in scientific circles, without serious readings, paracetamol in children's practice should not be applied, the more should not be abused.

This means of caution is prescribed in a complex with other drugs, and only under the supervision of the doctor, since the toxic effect may be observed from their interaction. The joint use of paracetamol and alcohol is prohibited.

During pregnancy

It is believed that paracetamol during pregnancy can be appointed when the risk associated with its use is justified by its high efficiency and extreme necessity. It should be borne in mind that a number of studies confirm the toxic effect on the fetus when using paracetamol during pregnancy. Thus, with this drug, the cases of the development of cryptorchism in boys, whose mothers used it, being pregnant.

Thus, the appointment according to the testimony of paracetamol during pregnancy should occur solely with the participation of a doctor.

Contraindications for use

Paracetamol is contraindicated in the following situations:

  • A history of individual sensitivity to it or other NSAIDs;
  • Liver disorders;
  • Pathology kidney;
  • Diseases associated with the deterioration of blood pattern;
  • Pregnancy;
  • Breast-feeding.

Storage conditions

Store in a dark, dry place at a temperature not higher than 25 ° C for 2 years. Bear from children!

Paracetamol is a popular pharmacological preparation, which has antipyretic and other drug abilities. Wide spectrum Actions, convenient pharmacological form, low price make a means popular among all segments of the population. Many ask, from which paracetamol helps. Possessing unique pharmacological properties, this drug is struggling with many health problems. To find out when and how to give a tool to children, adults, it is worth knowing the mechanisms of its impact, ways to eliminate, reading and contraindicating to use.

Pharmacological effect of the drug

To understand how Paracetamol acts, it is necessary to study its pharmacological principles of work. The drug perfectly absorbed the mucous membrane of the digestive system. The maximum concentration of the blood in the blood after the reception is achieved after 40 minutes.

The drug in the body is inhibited by the production of prostaglandins. These substances are produced under inflammatory processes of any nature, the appearance of fever and pain provoke. Most often, this state causes a cold. The medicine easily affects neurons, so effectively removes pain. In combination with anti-inflammatory abilities, the drug has an extensive range of use.

Indications for the use of paracetamol

Doctors prescribe tablets as antipyretic, anti-inflammatory and painful agent. Children is recommended children's paracetamol when teething teeth, inflammation in the oral cavity. The use of the means is possible in different pharmacological forms: oral pills and capsules in a special shell, soluble effervescent, syrup and suspension, candles (children's paracetamol), an injection solution. Everywhere the same composition is only characterized by an active substance content. You can use the tool at:

  • increasing temperature;
  • pain in the teeth and gums;
  • menstruation;
  • headache;
  • acne and acne;
  • hangover.

Paracetamol from temperature

The tablet effectively and quickly reduces the temperature. Any doctor will say that shoot down the heat lower than 37.5 is not recommended. This is a symptom of the inflammatory process, the reaction of the struggle of the natural forces of immunity against viruses, bacteria and other pathogens. But if an adult easily transfers such a state, then pain and malaise bring a lot of trouble to the child and his parents. Therefore, I want to help him. The substance has the shape of candles, syrup, tablets.

If the temperature of the infants from 3 months, then pediatricians recommend using candles with a dosage of 50 mg before or after meals. Reception - 4 times with smooth intervals per day. At the age of 3 months before a year, candles are used with a dosage of 100 mg or children's syrup. In such a video faster tool Chops the heat. At the age of 1 to 6 years, the dose is 200 mg at a time, 6-12 years - one-time reception of up to 500 mg. Paracetamol receptions periodically remove temperature readings. In the absence of heat, it should be immediately stopped to give medicine, as it does not have sufficient anti-inflammatory, antiviral abilities.

With fever, adults take the drug to take heat and pain no more than 5 times a day. One-time maximum - 500 mg of active substance in the form of syrup, injection. The combination of aspirin and paracetamol is popular with popularity. But you should not get involved in a similar means. Aspirin has a negative impact on the upper digestive channels, so often problems with the stomach after reception.

For dental pain

Paracetamol is able to occupy pain in inflammatory processes of oral cavity, gums and periodontics. Adults are taken: 1 tablet with a dosage of 0.5-1 grams no more than 5 times a day. Tabs from 3 years in teething and increasing the temperature during this period, paracetamol is given in the form of a candle or a special syrup with a single dose of not more than 100 mg. The medicine will not cure teeth and leave pain only for a couple of hours, so to solve the problem it is worth visiting the Cabinet of the Dentist.

From the pain during menstruation

Monthly many women are accompanied by strong painful sensations. To remove spasm at menstruation, doctors recommend using non-steroidal anti-inflammatory drugs. Paracetamol is popular among them. If the sensations are very strong, then increase the dose. You should not use more than 8 tablets per day. In this case, an overdose arises with all the consequences.

Paracetamol from headache

Headache, migraine retreat in front of paracetamol. To facilitate the state of adults take up to 500 mg of active substance in the form of tablets. If the daily dosage exceeds 4 grams of the drug, then side effects, poisoning and worsening health will quickly appear. In order for this not happening, it is necessary to read the recipe in detail.

The tool can effectively coat the pain of the head of various character and strength, but not more than 4 days in a row. Then the prostaglandins will be accustomed to receiving the means and the anesthetic effect will not come.

From acne and acne

Paracetamol tablet with external use quickly remove acne, angry rash. To do this, it is enough to grind the drug, add water and cook the casheam. Attach this tool to the affected area for 5 minutes. During this period, it will remove redness and inflammation from acne. On the day you need to do 4 such procedures. The medicine helps to remove the acne rash in a few days.

Remove pain, spasm of the head, remove the overall state of breaking after alcohol consumption can be a paracetamol substance. It does not have a negative impact on the stomach (as opposed to aspirin), therefore it will not provoke the appearance of nausea or heartburn. One-time reception is up to 500 mg of the drug, the daily rate should not exceed 4 grams.

After how much time paracetamol helps

Paracetamol quickly falls into the blood, sucking upper department digestive tract. The maximum concentration after the reception occurs after 40 minutes. Children knock the temperature with candles. Such a pharmacological form, the features of the metabolism of the children's body and the properties of the blood supply to the anus mucous membrane contribute to the injection of the funds after 10 minutes.

Is it possible to drink paracetamol during pregnancy and gv

Cold illness, fever on early timing Pregnancy is adjusted by paracetamol. In this case, you should accurately follow the instructions for use, do not exceed daily rate 4 g of drug and no more than 4 days in a row. Drinking paracetamol pregnant in the third trimester is not desirable. In the later stages of pregnancy, doctors prescribe analogues that do not have a negative impact on the fruit and kidney of the mother.

Paracetamol with GWs can be taken. Due to the fast-leading from the body (after an hour after use), it does not accumulate in milk. To protect the baby from the effects of medication on the body, it is worth not to feed it with breasts for an hour after using medication. The norm for removing pain or heat in a young mother is 1 tablet.

How to take: dosage to adults and children

Adults use paracetamol in tablets, syrup, candlelight. With any pharmacological form, the daily dose of medication should not exceed 4 grams, one-time - 1, 5 g. The instruction recommends taking an adult medicine from heat and pain:

  • Pills. 1-2 tablets (200, 250, 300, 500 mg dosage) After receiving food, the maximum amount of admission per day - 4 times;
  • Rectal candles. Maximum rate of 1.5 g of a valid means. One-time dose - 1 candle. The maximum amount of the drug per day - 4 times;
  • Syrup. 50 ml 4 times a day with smooth intervals.

Reception of the drug by children depends on their age and mass. For treatment use:

  • Pills. Aged 3 to 6 years - the daily rate of the means is not more than 2 grams. Reception - 1- 2 tablets at a dosage of 120-200 ml;
  • Syrup. Not more than 4 receptions per day. Age and dosage: from 3 months to 1 year - 2.5-5 ml; 1-6 years - 5-10 ml, from 6 to 12 years - 10-20 ml;
  • Candles. Up to 3 years - 15 mg per kilogram, 3-6 years - up to 60 mg per 1 kg; 6-12 years old - up to 2 grams per day.

Contraindications

Reception of paracetamol does not always bring relief, because there are contraindications to its use. This popular drug cannot be used to remove pain or heat when:

  1. The age of the patient up to 1 month;
  2. During the period of tooling the baby or breast feeding (lactation);
  3. With any shortness of the liver;
  4. Kidney problems;
  5. Allergies on the active substance.

If there are at least one contraindication, the doctor picks up other painkillers or non-steroidal anti-inflammatory drugs.

Side effects

The effect of medication in violation of the instruction, dosage provokes side effects. Overdose may cause:

  • rash, redness, "urticaria". Allergy to the tool most often has such external manifestations;
  • stomach ache. The stomach reacts to the wrong reception or dose;
  • drowsiness, I want to sleep. The cause of the state is low pressure;
  • liver or kidney dysfunction;
  • a sharp drop in the level of glucose, hemoglobin in the blood.

With dosage violation or not proper reception It is worth calling an ambulance.

Cost of preparation

Many are interested in: how much is paracetamol in the pharmacy. The price depends on the pharmacological form of the means, dosage, packaging, to which network belongs to the pharmacy. The cost is:

  • Pills. Packing 10 pieces of 200 mg dosage - from 4 to 6 rubles, 10 pieces of 500 mg dosage - from 9 to 12 rubles;
  • Candles with a dosage of 500 mg 10 pieces - 40-60 rubles;
  • Syrup 100 ml - 60-80 rubles;
  • Suspension with strawberry taste for children 10 ml - 70-90 rubles.

Paracetamol analogues

There are analogues containing paracetamol and additional active ingredients or having others medicinal substances. The selection of analogues of nonsteroidal anti-inflammatory nature or painful pills only the doctor is engaged. This decision is made in the presence of contraindications, allergic reactions and other serious reasons. These drugs for pain relief, inflammation and heat include:

  1. Panadol. Active cocktail consists of paracetamol and caffeine. Applied to remove heat pain sensations Various strength and character. Produced in the form of oral tablets. Adults and children over 12 years old take 1-2 tablets with a dosage of 500-1000 mg to 4 times a day. The norm per day is not more than 4 grams of the drug.
  2. Barallgetas. The active ingredients of Analgin, Pitoophenon remove inflammation, heat in children and adults. Pharmum - tablets. The daily dose is no more than 6 pieces, the duration of the reception is no more than 5 days. Dosage: adults - 1-3 tablets at a time to 3 times a day; Children: 6-8 years old - half of the capsule, 9-12 years old - ¾, 12-15 years old - 1 capsule no more than 2 times behind the knocks.
  3. Nimid.. Nimes Nimesulida . It struggles with elevated temperature, pain and inflammation. As an analogue of paracetamol is used in the form of pharmacological forms of tablets, granules and suspension. Take: adults and children over 12 years old - 100 mg 2 times a day, kids up to 12 years -1.5 mg per 1 kg of weight, the norm is divided into two receptions.

It is prescribed at high temperatures on early stages Sleepy respiratory viral infections To facilitate the state of the patient. The doctors of the whole world Paracetamol is included in the international list of drugs necessary for humans. It has properties not only antipyretic, but also acts as an analgesic and anti-inflammatory agent.

How does this drug work

Paracetamol has an impact on the human brain, namely, its pain and thermostat centers. It stops cyclooxygenase (enzymes causing an increase in temperature) in the central nervous system And practically does not have a negative effect on the mucous membrane of the stomach. Also, the drug has a very weak anti-inflammatory effect. Therefore, it is not used with pain with strongly pronounced inflammation.

Paracetamol is shown for symptomatic treatment painful syndrome of various origin of light and medium intensity:

  • headache;
  • toothache;
  • neuralgia;
  • back pain and joints;
  • menstrual pain.

This medicine is made in the form of tablets, suspensions, syrups, as well as in the form of candles.

Correct reception:

  1. Tablets should be taken inside by drinking with plenty of water (at least 100 mm). If you wash the tablet with warm milk, it will work faster. Do not drink tea and coffee. These two drinks contain a large amount of caffeine, so it is possible a violation of metabolism drug in organism. Paracetamol must be taken 1-2 hours after eating so that the effect of the drug was more efficient. If the medicine is used immediately after eating, its suction slows down, respectively, its impact on the body slows down. If you use paracetamol before meals, it can lead to problems associated with the gastrointestinal tract. Paracetamol begins to operate on time, the maximum effect is achieved after 2 hours. In some cases, the effect may not occur within two hours or more. This is due to strong spasms or low liquid. Recall that paracetamol is needed to drink with plenty of water - only then it will work quite quickly. If you take it, without drinking, then it may not work. Its dosage is appointed by the attending therapist. Fully excreted from the body 6 hours after the last reception of the drug.
  2. Paracetamol syrup in appearance is a yellow viscous liquid, sweet with a tart taste and a fruit smell. In this form, the medicine is prescribed to children from several months to 6 years, as it is difficult to swallow the babies to the tablets. After receiving the medication, the active ingredients are absorbed by 90%, which necessitates the rapid result and the child soon feels relief. The effect of the drug occurs in the flow. The medicine is completely excreted after its last application.
  3. The main difference between the suspension from the syrup is the absence of alcohol and the smaller sugar content. The medication is a viscous pinkish liquid with a pleasant, fruit aroma. The active substance here is paracetamol. The auxiliary substances are glycerin, methyl aprichedroxybenzoate, liquid sorbitol, xanthan gum, citric acid. Suspension or syrup must be pre-stabbed, then pour into a measuring spoon and swallow, drinking with plenty of water.
  4. Candles. In the form of a suppository from white to white with cream or white with a yellowish color tinge, a solid torpedo-shaped form. The main substance here is paracetamol, and the auxiliary substance is a solid fat basis. The main advantages: the lack of dyes, a longer effect compared to syrup and suspensions, are used rectally.

Paracetamol does not knock the heat at subfebrile permanent temperaturecaused by protracted chronic viruses in the body.

Paracetamol contraindications

When using this drug, you need to know about contraindications, namely:

  • if you suffer alcoholism;
  • it is impossible to give children under 6 years;
  • there are problems with kidney or liver;
  • any blood disease is characteristic.

With a frequent use of paracetamol, you can not improve, but, on the contrary, worsen your condition, since the excessive use of this drug leads to problems with the liver and kidneys. Over time, you will notice that this medicine no longer helps. After that, you most likely decide to move to a more potent medicine and thereby harm even stronger to your body.

Overdose

Overdose occurs when taking this drug more than 10 g / day. For patients with alcoholism, dose in the amount of 2.5-4.0 m / day is already an overdose.

Incication takes place in 4 stages:

  1. At the first stage, the symptoms are not critical: diseases, nausea, sweating, pain in the right hypochondrium, loss of appetite. Approximate duration of -cakes.
  2. At the second stage, the symptoms are more pronounced: a decrease in temperature and arterial pressure, vomiting, kidney and liver damage, pancreatitis, cramps. Approximate duration of 2-3 days.
  3. At the third stage, one of the strongest and complex symptoms: severe vomiting, liver necrosis, hepatic encephalopathy, which can lead to a coma, reduction of sugar levels, heat, manifestation of jaundice, myocardiodestrophia. The duration is from 3-5 days.
  4. This stage is the most critical: death.

When poisoning, you should know how to properly provide first aid. For this you need:

  • rinse the stomach using a large amount of water;
  • drink activated carbon (1 tablet by 10 kg of body weight);
  • drink a laxative so that the medicine does not have time to touch the stomach and intestines;
  • correct.

Finally, it is worth noting that paracetamol rarely causes any allergic reactions, it is quite well interacting with other drugs. But it should be remembered that this medication still does not treat, but acts only on symptoms.

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From what helps and how to take a children's paracetamol syrup - instruction

All do not first know about the antipyretic preparation paracetamol. It is released in various form: Tablets, capsules, suspension. This article discusses children's paracetamol syrup: instructions for use, contraindications, side effects and dosing mode.

The composition of children's antipyretic

Syrup for children belongs to the group of analgesics (painkillers) and antipirectrics (drugs that reduce body temperature). Also has a weak anti-inflammatory action. Basic acting - paracetamol. In 5 ml of a transparent viscous fluid, the dosage of the active component is 120 mg. Additional substances included in the syrup:

  • glycerol;
  • ethanol;
  • flavoring;
  • purified water;
  • propylene glycol;
  • sorbitol;
  • methyl apograproxybenzoate;
  • propilepagidroxybenzoate.

Strawberry syrup has a pleasant taste and smell, also produced paracetamol with raspberry taste.

Indications for use

The use of paracetamol in therapeutic purposes is widely. The medication tool is prescribed with a headache of any intensity. The therapists and pediatricians are always recommended to have Paracetamol Children's Syrup in a home aid kit. It is effective when increasing the temperature caused by influenza, respiratory diseases. Paracetamol has found its use in hyperthermia in post-calcinal reactions. Is it still helped by this medicine?

Since syrup refers to analgesic means, it helps with any pains:

  • muscle;
  • in the compression of spinal roots;
  • in teething;
  • if the internal organs are damaged;
  • in case of damage to the skin;
  • traumatic;
  • abdominal.

Paracetamol is taken with lactation and pregnancy, Malgia and Neuralgia.

Application Scheme and Dosing Mode

How to give a paracetamol syrup? The medicine is intended for internal use. Give it in accordance with the weight or age of the child. The application scheme may differ. It depends on the reason why the doctor appointed a child or adult paracetamol.

Table

Instructions for the use of medication to children in accordance with weight with increasing temperature during a period of viral or infectious disease.

The interval between paracetamol techniques should be at least 4 hours. If the child is less than 2 months, then after the recycling of the medication, it is necessary to consult with the doctor regarding the further use of paracetamol, if it does not help. The course of treatment with the preparation is three days, with pain - 5 days.

How to give children if the temperature is raised after vaccination? In hyperthermia in post-specific reactions, paracetamol is taken only as necessary. How much to give? It is possible a disposable use of medication in accordance with the weight of the child. When losing a measuring cap or a syringe, use a teaspoon. It contains 5 ml of liquid.

How to use medication? The medicine is drunk 2 hours after meals, drinking a large amount of liquid. Breast children can produce a drug in milk or water.

If the use of the antipyretic medicine is not enough, and the temperature quickly rises, alternate paracetamol with other medicines, for example, containing ibuprofen. These include:

Application for lactation and pregnancy

Children's paracetamol Syrup of a nursing mother can be taken after consulting the therapist. The active ingredient falls into breast milkbut in small quantities, so the medicine can be taken with GW. Of course, a pregnant woman is better not to take any medicines to avoid complications. But the high temperature is much more dangerous for the child than the use of paracetamol. According to the method of action, the medicine is similar to aspirin and analgin, but much safer with breastfeeding and pregnancy.

Dosage medication for pregnant women and nursing mothers: Syrup from temperature takes 3-4 times a day, one-time use should not exceed 500 mg. The maximum daily amount can be 1.5-2 g of syrup.

Important! If you observe the interval between the use of another dose, then the minimum content of the active substance in breast milk will be minimal.

Paracetamol is considered the most efficient and safe among all antipyretic and painkillers, allowed in the application during the period of nourishing the child and breastfeeding.

How much does the syrup action begin?

How much does the drug act? The medicine begins to shoot symptoms 15 minutes after its use. How quickly the medicine is not enough. Usually, in full force, it will unfold after the transformation into a liquid mass is reached the gastrointestinal tract. That is why it is necessary to drink syrup with plenty of water to launch its activation. The full achievement will begin after 30-60 minutes.

Important! If you do not put the medicine with liquid, it may not act at all.

Contraindications for use and medicinal interaction

Before using the medication, carefully read the instructions so that it does not appear later, which will not regret. Contraindications for the use of paracetamol:

  • increased sensitivity to drug components;
  • blood diseases;
  • hepatic I. renal failure.

Paracetamol is also prohibited to be used together with activated carbon, another medicine containing the same active ingredient. The following means cannot be used with syrup:

Important! The drug cannot be taken with simultaneous use of anticoagulants, anticholinetics, oral contraceptives, uricosuric agents.

Overdose

Cases of overdose arise rarely. Its appearance is possible if you exceed the daily rate of the drug. The adoption of more than 10 g of the active substance will cause intoxication undergoing 4 stages. Paracetamol overdose is fatal if you do not start acting on time. The main thing is to immediately provide first aid and call an ambulance. Symptoms of overdose:

  • strong sweating;
  • nausea;
  • pain in the ribs on the right;
  • bad appetite;
  • lowering blood pressure and temperature.

In the third stage, the signs are brighter expressed. The patient has convulsions, the kidneys and the liver are damaged, the strongest vomiting opens. It can lead to a liver necrosis, a decrease in blood sugar, myocardiodistracy.

Attention! The duration of vomit urges for more than 3 days, ignoring symptoms will lead to death.

If the child accidentally drank a large amount of medication immediately rinse him with a large amount of water, give activated carbon on the basis of dosage 1 tablet by 10 kg of weight and call an ambulance.

Paracetamol side effects

Side effects after applying drugs rarely appear. Basically, their emergence is possible if the patient takes the drug for more than 5 days. They can be expressed in the following:

  • skin itch;
  • swelling of subcutaneous tissue, leather and mucous membranes;
  • acute inflammatory process in skin cover;
  • abdominal pain;
  • improving the activity of liver enzymes;
  • layella syndrome;
  • hypoglycemia;
  • renal colic;
  • thrombocyses;
  • dizziness;
  • slow reaction.

Attention! In addition, the occurrence of hypoglycemic coma and anemia, papillary necrosis and aplastic anemia, leukopenia and barcitopenia may occur.

Cost of medication

The price of paracetamol depends on the form of release (100 and 50 ml), the manufacturer, and the selling pharmacy. For example, Borschagovsky HFZ produces a medication in a volume of 50 ml with a cost of 32.90 rubles, and 100 ml costs 123.7 rubles.

Paracetamol has many analogues. If the medicine for some reason does not fit, it is possible to replace it with Efferhalegan, paramol, febridol, celifun, methamol, biocetamol, acetophene, indangol, peyrinazine, deminopen.

How much does paracetamol begin to act?!

45 minutes ago gave 1 tablet of children's paracetamol, the temperature fell only by 0.2 degrees (it was 38 became 37.8)

we only hit the temperature with Nooofen and acted immediately)

Damn no nourofen (((

we have when the teeth were cut, constantly gave the pain) another did not even use)

I gave Dentocinda from the teeth, we helped us well.

Alen, is it syrup?

yes) Children's Syrup) There is still such a syringe in the slipper)

pPC (((does it not work?

There are such, but this is also paracetamol, I bought and candles and pills, just gave a tablet, because I was afraid to put a candle and in general I will not do how to do it ((((never came across. She will break away

it fell enough long enough. hour and a half. But it slept for a long time. Only I offered an inadium all the time. Wait. Soon will fall.

Damn, horror, I hope it will fall. My generally very little water drinks (((maybe give juice?

Yes, she does not hurt, it is after vaccination

well, waving a dilution

If after an hour it did not fall (for example, on degrees), it means that it does not work. Then you can give nurofen (there is another active ingredient, ibuprofen, and not paracetamol).

We were told in the urgent, so I answer the words! :) You try more physical methods, at least, skip (summer, but never know).

Thank you! We are in panties only, even diapers shot

we advised the doctor of the candle, they act faster, it is possible to wipe well water, too well helps, straightly wipe it until it will not get cold and disappear and disappear

agree. or vodka. The most important thing is not to smear the region of the heart and the side of the chest and on the back side.

early shot down, actually, but the tablet is already valid

We have after vaccination the temperature, the doctor said after 38 shoot down

immunity only after 38 begins to work, but you decide

Yes, all doctors speak differently, you do not know who to listen ((

we, too, in the hospital after 38, the Soviet to shoot down, but now medicine is such, instead of encouraging the work of immunity, they advise to shoot down and treat the child with medicines. Because otherwise, doctors will have almost nothing to treat. I still have 1 time only the antibiotic gave and knocked the pace 2 times at night to sleep calmly and then I think, if it were not for excessive role-minded excitement for a child

Yes, I have to be honestly at all, there was a panic, we have never been hurting yet and we never had a temperature. So I was absolutely not ready

That's right, after vaccination you need to shoot down. After 38, if it rises - it will be difficult to knock, can grow sharply to seizures. Better 3 days after vaccination, give 3 times a day of Ibufen or Nurofen. My baby is difficult to vaccine tolerate, I already science

cramps and from a sharp decline can be. In general, the doctor says me that it is not dangerous and passes with age. But it looks scary, I agree

Eh, poor kids.

It may not help at all ((usually it is possible to give again after an hour, if it does not help.

where is the hour, although it did not help us

And how much is your baby?

Mom will not miss

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Our calendar of pregnancy opens you the features of all stages of pregnancy - an unusually important, exciting and new period of your life.

We will tell you what will happen to your future kid and you in each of the forty weeks.

Children's paracetamol Syrup and suspension

Paracetamol Children is widely used as antipyretic and painkillers for children, according to instructions for use, syrup - from 2 years, suspension - from 3 months.

Structure

The composition of the liquid suspension paracetamol is 120 mg, 5 mg, packaged in 100, 200 ml bottles, equipped with instructions for children, includes:

  • active substance - paracetamol with a content of 120 mg of the active component by 5 ml of solution;
  • auxiliary compounds - sorbitol, glycerin, citric acid, aromatizers "strawberries", "Orange".

In addition to the Paracetamol of Children, for the treatment of children, a suspension of paracetamol bey 120 mg, 5 ml, which is used in the same dosage is used.

Syrup is produced in tanks 50, 100 ml. Contains, except for the active component, sugar, citric acid, sodium citrate, ethanol, flavoring additives.

Replace Paracetamol Paracetamol Syrup can be bubble with Panadol Bebi syrup, which contains the same active substance in an amount of 120 mg, but these funds are not permitted, as indicated in the instructions for use, for children with diabetes.

Medicines are released without a prescription, which indicates their relative safety.

Properties

Paracetamol is an antipyretic and analgesic agent from anilide group, contained in preparations Panadol, children's tilenol, Panadol soluble pills, efferralgan, digital, Perfalgan.

Paracetamol is a symptomatic means, intended to eliminate the symptoms of the disease. For the treatment of children, it is convenient to use liquid formations of paracetamol - syrup and suspension. With this treatment, it is easier to disguise the taste of medication flavor.

The compound is capable of penetrating through the hematorecephalic and placental barrier. The active ingredient affects directly on the centers of the brain responsible for the regulation of temperature and pain.

Pharmacological action The means consists in blocking the activity of the cyclooxygenase enzyme in the central nervous system, which oppresses the production of inflammation factors of prostaglandins.

Peripheral anti-inflammatory action does not have it, since its activity is blocked by cell enzymes peroxidases. This property makes a safe taking medication for the diseases of the stomach, in the elderly and childhood.

Pharmacokinetics

Half-life, for which the concentration is reduced by 2 times and becomes below the therapeutic, is 4 hours.

Metabolism occurs in the liver, where 80% of the drug binds, forming inactive metabolites. The rest is transformed, forming active intermediate compounds that are neutralized with the participation of glutathione, cysteine \u200b\u200band mercapturic acid.

The lack of glutathione's body leads to blocking the enzyme activity of a structural unit of the liver (hepatocyte) with the development of its necrosis. Such a danger is created in the overdose of the drug.

Paracetamol metabolites are removed from the body by the kidneys during the day by 95%.

Indications

  • Pain dental, head, articular, burn, caused by injury, otitis, pharyngitis, angina;
  • increased temperature infectious diseases, Introduction Vaccine.

When using paracetamol in the syrup for the treatment of children, it must be remembered that sugar and ethyl alcohol come into the syrup.

In suspension there are sucrose, 5 ml medicinal solution contain 0.25 x (bread units), which should be taken into account in the treatment of children suffering from diabetes.

Contraindications

  • Blood disease;
  • children's age less than 1 month for suspension, 2 years - for syrup due to the presence of ethyl alcohol;
  • the absence of enzyme glucose-6-phosphate dehydrogenase due to heredity;
  • fructose intolerance;
  • lack of sugar.

Caution prescribed medicine during liver, renal failure. Under the control of the doctor, babies suspension are taken from 1 to 3 months.

In individual cases, the dosage correction may be required. The use of the means is limited during gastritis, a stomach ulcer.

Application, dosage

Suspension and syrup take to meals, about an hour or 2 hours, well drinking. Drugs are not diluted. More than 4 hours can not be taken.

The period, after how much paracetamol is beginning in syrup and suspension, is usually 20 minutes, but may manifest after 1.5 hours.

Syrup

Paracetamol Children needs to be taken to children before eating up to 4 times / day, as indicated in the instructions for the use of syrup, in the daily dosage corresponding to the age and weight of the body.

Before treatment, the agent is shaking. For dosage of syrup, Paracetamol children's use in a chain. A spoon, the amount of active substance in which is 120 mg.

Single reception of the syrup is in a child:

  • starting from 2 to 3 years - 0.5 - 1 teaspoons;
  • after 3 to 6 - from 1.5 lies. up to 2 hl.;
  • from 6 years to 12 years - 2-3 chain. lies.;
  • after 12 years - from 3 to 5 chain. lies.

Suspension

Before use is good.

  1. The dosage of the Syrope Paracetamol Children's for the treatment of children is prescribed depending on the weight, in proportionMG / 1 kg.
  2. The daily dosage should be less than 60 mg / 1 kg.

Suspension is used up to 4 times a day. It is convenient to dose the medicine using a measuring cup. 1 ml of suspension contains 25 mg of paracetamol.

  • in 1-3 months. - 2 ml;
  • 3 months - 12 months. - from 2.5 to 5 ml;
  • 12 months - 6 years - 5 ml - 10 ml;
  • from 6 - to14 years - 10 ml - 20 ml.

Without consultation, the doctor is allowed to use from 3 months:

  • not more than 3 days to reduce the temperature;
  • not more than 5 days for use as analgesic.

Side effect

Treatment may cause allergies in the form of skin rash, itching, angioedema edema.

Dangerous side effects include a decrease in blood glucose with long-term reception of drugs, which can cause hypoglycemic to whom. With long-term treatment, it is necessary to control the amount of glucose in the blood.

The drug in overdose damages the liver. A dangerous dose for children is the reception of 10 g of the drug.

Signs of excess dosage

When overdose, symptoms develop during the day:

  • nausea, vomiting;
  • pain with localization in the abdomen;
  • skin pallor;
  • violation of the work of the branchal immimination.

With a significant overdose, there is a violation of the work of the kidneys, pancreas, arrhythmia. Overdose may be complicated by renal failure, coma.

special instructions

In the treatment of children with particular attention, it is necessary to strive to avoid overdosing paracetamol, and simultaneously use 2 or more medicines containing this active substance simultaneously.

It is impossible to simultaneously use paracetamol in high concentration and salicylates. This can cause side effects in the form of a tumor kidney or bladder.

In addition to this topic, read:

Adult ear bump

Rubber in Nursing Mom, Treatment with drops and folk remedies

Signs and treatment of sinusitis in adults

Cheap drops from a cold

Treatment of laryngitis in adults at home

How and what to treat an angina in a child for 2 years

By self-medication, you can miss the time and harm health!

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Paracetamol - syrup for children

Each of us is familiar with such a drug like paracetamol. It is inexpensive but very effective tool It is used to facilitate the state with pain syndrome, as well as a decrease in body temperature in case of colds and other diseases.

For children under 12 years old, paracetamol is produced in the form of a syrup, which has a pleasant taste, thanks to which it is happy to take the guys of different ages. In this article we will tell you which components are part of this medication, and how it needs to be given to a child in order not to harm the baby's health.

The composition of the children's antipyretic syrup paracetamol

In 1 ml of syrup, it contains 24 mg of paracetamol - an active substance that has an antipyretic and analgesic effect. This concentration does not cause significant harm. children's bodyBut at the same time sufficient to quickly and effectively improve the overall condition of the baby and save it from unpleasant symptoms.

In addition to the main ingredient, the composition of this drug includes many auxiliary components, namely: citric acid, propylene glycol, riboflavin, ethyl alcohol, sugar, sorbitol, sodium benzoate, sodium lemon-chosen threeness, as well as water and various aromatic additives.

How to give a children's paracetamol in syrup?

According to the instructions for use, the dosage of the children's syrup paracetamol depends on the age and mass of the baby's body. When calculating a permissible dose, based on the patient's weight, it should be remembered that at once the crumb should not be obtained by the medicine for 1 kg of body weight. At the same time, the daily dosage cannot exceed 60 mg per 1 kg of babes weight.

Relying on the age of a small patient, doctors prescribe a paracetamol-based syrup for children in the following schemes:

  • newborn babies that were not fulfilled 1 month, this remedy is categorically contraindicated;
  • carappusams aged 1 to 3 months, paracetamol syrup can be given solely by appointment and under the strict control of the doctor. In this case, the one-time dosage should not exceed 2.5 ml;
  • tabs from 3 to 12 months can be taken from 60 to 120 mg, or from 2.5 to 5 ml. Reception frequency for 24 hours;
  • preschoolers from 1 to 6 years old can be given 5-10 ml, or MG drug in the morning, day and evening;
  • finally, the guys from 6 to 14 years old can be taken with a syrup in every 4-6 hours.

Without appointing a doctor, this drug can be given to the baby for a limited period of time. Thus, in order to reduce the body temperature, it can be used not more than 3 days in a row, and as an anesthetics - no more than 5 days.

Most of the young moms and dads who seek help to this drug are interested, through how much the Paracetamol children's syrup act, and how to understand whether it has the necessary effect. As a rule, a decrease in the increased body temperature after using paracetamol in syrup occurs, therefore, it is precisely such a number of time that it is possible to draw conclusions about how efficient the medicine in this particular case.

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How much does paracetamol act? How long does an action begins?

Paracetamol, refers to antipyretic means. I know by myself, in order to start acting a Paracetamol tablet, must pass more minutes. It also also applies to liquid paracetamol-based syrups, which I give a child at least 30 minutes, and only then you can see its action.

Within an hour, paracetamol must act and the temperature should start falling. If more than an hour passed, and the temperature stands on the spot, does not fall, then paracetamol did not affect, and you need to take another drug, for example, based on ibuprofen.

Paracetamol-containing preparations are produced in the form of syrups, tablets, candles. Any drug that contains paracetamol, begins to act. And the time of paracetamol is about 2 hours.

Paracetamol begins to act at once, about only 15 minutes after it is drinking. After 30 minutes, its effect will already be good noticeable. In the case when 30 minutes after taking the temperature, the temperature did not sleep, you need to take another drug or cause an ambulance.

Paracetamol begins to reduce the temperature of minutes after 20, not earlier, it can after 30 minutes.

The higher the temperature, the slower the paracetamol begins to operate, some take two tablets at once, if the temperature is almost 39, although it is better to accept the analgin tablet.

Paracetamol is a rather popular painkiller and antipyretic agent. It is not toxic, does not affect blood formation and coagulation, evenly distributed in the brain. In addition, paracetamol is produced in addition to traditional tablets also in the candlelight, which is also convenient. Paracetamol begins to act about 20-30 minutes, when taking inside - a little over a larger time, when setting a candle, a little earlier. But as an anti-inflammatory preparation, paracetamol is ineffective - it acts on the central nervous system, and not to the peripherals. That is, this drug cheat nervous system. The action of paracetamol lasts about 4 hours, and after 4.5-5 hours the drug is completely excreted from the body.

Paracetamol begins to actively act only when it is molding with plenty of liquid. If you just swallow it, then he may not act at all as you expect from him. The active substance should turn into a stomach into a liquid mass, and then only this mass is absorbed into the blood. Therefore, the drug is poorly acting in the treatment of kids.

Paracetamol syrup is still using a syringe with a syringe, but the waters of the half-table required to activate this syrup are not free to activate, unless with the scandal and violence.

A complete achievement of the result occurs with proper reception, and three hours after normalization of the temperature, the effect of the drug passes and a new attack begins. 6 hours after taking inside the drug completely excreted from the body through the liver.

In contrast to paracetamol, ibuprofen preparations and acetylsalicylic acid help, which is called dry. Therefore, the reaction of the body is bright on them. And the action is longer, up to 6 hours. Plus two to remove the remains of the active substance from the body through the kidneys. Only 8 hours.

So as not to make an overdose and do not load organs strongly, drink symptoms once, alternating paracetamol and acetylsalicylic acid. If the temperature is very high, it is possible to drink together: a paracetamol tablet and acetylsalicylic tablet, but it is not necessary to abuse. In just a day you can drink 4 paracetamol and 3 aspirin.

The child has paracetamol very quickly knocks down the temperature, after 15 minutes its action is already begins. The husband, when the anelli was sick, also took paracetamol, but its action began only after 30 minutes.

I have a neighbor in a hostel, which Put Paracetamol in any occasion, even though it hurts the throat, even though the stomach or began snot, he is the sun equally as Paracetamol. According to him, I can say for sure that the drug action takes place within ten or fifteen minutes. I will leave this, the pros: first, it treats all diseases, secondly, speed. Cons: heavily go on the liver.

Preparations that contain paracetamol in their composition, begin to exert the antipyretic effect after receiving, and continue to be operation within 4 hours.

From the body, paracetamol is completely excreted after 4.5 hours, and most of it is removed by the kidneys (about 98%). Also, paracetamol practically does not affect the gastric mucous membrane, but this also played a cruel joke with a medicine, since thousands of people with overdose are treated annually (there are lethal cases), because some drink it mindlessly, exceeding a much dosage, and That mixing with alcohol.

At my child, the temperature begins to fall, after 30-40 minutes. If this did not happen, even an hour, then it is worth trying another antipyretic, but not again paracetomol. For example, Syrufen syruphen helps very well.

About fifteen minutes later, you will feel how he began to act. In full force, it will unfold in thirty minutes. If within 30 minutes - an hour does not act as, then other measures can be taken.

Medical Reviews, Description, Medicines, Medication Rating, Application Instructions, User Reviews, Special Instructions, Side Effects, Overdose, Application, Indications

reviews 1.

Paracetamol syrup for children - Analgesic Antipiretik. It has an analgesic, antipyretic and weak anti-inflammatory effect associated with the influence of paracetamol on the center of thermoregulation in the hypothalamus and the ability to inhibit the synthesis of prostaglandins.
When taking inside, about 90% of the administered dose of paracetamol is absorbed. The degree of absorption decreases with simultaneous reception with food. The maximum concentration of paracetamol in the blood plasma is reached after 30 - 90 minutes. The drug is evenly distributed in body fluids, the volume of its distribution is 0.95 l / kg. Binding with plasma proteins is insignificant. Actively metabolized in the liver. In infants, the intensity of metabolism is less pronounced. The half-life of paracetamol is 1.5-2.5 hours. It is removed mainly by the kidneys, and less than 4% - unchanged. Approximately 85-95% of the therapeutic dose is derived from the urine within 24 hours. In renal failure, the elimination of paracetamol slows down, the accumulation of conjugates is observed. With severe liver diseases, the half-life of the plasma preparation increases significantly, but the clinical significance of this phenomenon is unclear.
In newborns and children under 10 years old, the main metabolite is paracetamol sulfate, while adults are a glucuronide conjugate. However, this does not affect the rate of elimination of the drug.

Indications for use:
Paracetamolchildren applied with hyperthermia with a cold, flu and after vaccination. Pain syndrome of moderate and average intensity of various genesis (head and dental pain, Malgy).

Is paracetamol safe for children?

When introduced in the right doses, it can help treat a number of ailments. People use paracetamol for several years to treat pain due to injury or illness. In fact, this is the first line of treatment that doctors and parents prefer to treat fever and pain. The drug is well tolerated by children of all ages and practically does not have side effects when used in recommended doses.

So, when should you give paracetamol to your child?

Paracetamol is usually used for. However, doctors may decide against the use of the drug for low fevers. Headaches: Sometimes high temperatures can cause body pain, headaches and common discomfort in children. Relaxing body pain, headache, toothache or stomach, medicine also helps the child to sleep well at night. Symptoms of colds or flu are reduced when you give a paracetamol child. However, you cannot treat a cold or flu with medication. Fever is a common side effect of vaccination. If a child gets vaccine vaccinations, your doctor can recommend paracetamol to reduce the temperature. The pain due to stretching in the body can also be reduced by paracetamol.

  • Paracetamol dose can help reduce fever and relieve symptoms.
  • The medicine usually reduces the gravity of pain, but does not remove it.
  • Pain in the body can also be alleviated by paracetamol.
If a child has a high temperature or unbearable body pain, paracetamol cannot help.

Mode of application:
Paracetamoltake inside. The dose of the drug for children depends on the body weight of the child. One-time dose is 15 mg / kg, the maximum daily dose for children should not exceed 60 mg / kg.
Recommended doses: Children aged from 2 months, in which the heat appeared after vaccination appeared 2.5 ml (60 mg of paracetamol), if necessary, you can repeat the dose after 4 to 6 hours. If the body temperature does not decrease after the second reception, you need to consult a doctor.
Body weight - 4 - 8 kg: one-time dose - 2.5 - 5 ml (60 - 120 mg of paracetamol);
body weight - 8 - 12 kg: one-time dose - 5 - 7.5 ml (120 - 180 mg of paracetamol);
body weight - 12 - 16 kg: one-time dose - 7.5 - 10 ml (180 - 240 mg of paracetamol);
Body mass - 16 - 20 kg: one-time dose - 10 - 12.5 ml (240 - 300 mg of paracetamol);
Body mass - 20 - 24 kg: one-time dose - 12.5 - 15 ml (300 - 360 mg of paracetamol);
Body mass - 24 - 32 kg: one-time dose - 15 - 20 ml (360 - 480 mg of paracetamol).
The drug is accepted up to 4 times a day. The interval between the methods of the drug should be 6 hours. Dosage - with a dosing cup having a calibration: 2.5 ml, 5 ml, 10 ml, 15 ml, 20 ml, or a dimensional spoon, which has a graduation of 2.5 ml, 5 ml. The maximum duration of treatment without consulting a doctor - 3 days with hyperthermia and 5 days - with pain syndrome.

Paracetamol dosage for children

Even if a small fever or pain is not weakened after receiving paracetamol, take the child to the doctor. After receiving in the right doses, paracetamol can alleviate pain and fever. But do you know that the wrong dose of ordinary home medicine, such as paracetamol, maybe fatal?

Paracetamol for babies and babies

Before using a medicine from fever, you need to know how much you can give the child someday. Continue reading to find a suitable dose of paracetamol for the age of a child. You can also give paracetamol for children aged three or more months. The dose you must give depends on the age of the child. An ideal option here will be paracetamol suppository for babies, not pills or syrups. However, it is better to follow the advice of the doctor.

Side effects:
Like other drugs, Paracetamol Childrenmay cause side effects of varying severity.
Allergic reactions: skin itching, erythematous rashes on the skin and mucous membranes, angioedema edema, multiform exudative erythema (including Stevens-Johnson syndrome), toxic epidermal necrolis (Layella syndrome);
From the CNS side (usually develops when taking high doses): dizziness, psychomotor arousal and violation of orientation;
From the digestive system: nausea, pain in the epigastric region, an increase in the activity of "liver" enzymes in serum, as a rule, without the development of jaundice, hepathonecosis (dose-dependent effect);
From the endocrine system: hypoglycemia, up to the hypoglycemic coma;
From the side of the blood formation organs: anemia, sulfgemoglobinemia and methemoglobinemia (cyanosis, shortness of breath, heart pain), hemolytic anemia. For long use in doses exceeding therapeutic, aplastic anemia, pancytopenia, agranulocytosis, neutropenia, leukopenia, thrombocytopenia;
From the side of the urinary system (when taking large doses): nephrotoxic effect (renal colic, interstitial jade, papillar necrosis).
In case of any side Effects It is necessary to immediately stop the use of the drug.
Interaction with other medicines and other types of interactions.
In patients who took phenytoin, rifampicin, barbiturates and tricyclic antidepressants, alcohol, it is possible to increase paracetamol half-life and increase the risk of hepatotoxic action. Paracetamol reduces the effectiveness of diuretics. Increases the effect of indirect anticoagulants. Strengthens the toxicity of Levomycetin. Microsomal oxidation inhibitors (including cimetidine) reduce the risk of paracetamol hepatotoxic effect. Metoklopramid and home dervidon increase, and the cholestyramine reduces the absorption rate of paracetamol.
The simultaneous use of high doses of paracetamol with isoniazid increases the risk of hepatotoxic syndrome. The simultaneous use of paracetamol and hepatotoxic agents increases the toxic effect on the liver.
Long-term sharing of NSAIDs increases the risk of developing "analgesic" nephropathy and renal papillary necrosis, the occurrence of the terminal stage of renal failure.
With the simultaneous use of any other means, you should inform the doctor.

Paracetamol for kids and young children

Always make sure that you give more than the prescribed doses. Kids are vulnerable and can get a fever due to fatigue, the effects of a warm or cold climate or when they remove vaccination. At this time you can give a child a dose of paracetamol to reduce the fever. Use this diagram as a reference material, and also talk to your doctor before giving the child this medicine.

Paracetamol for children older than six years

The drug should be administered in four separate doses within 24 hours. Unfortunately, most parents do not pay attention to the dosage recommendations, they consult with their doctors. This can lead to paracetamol even in the overdose of children.

Contraindications:
Contraindications for use. Children's syrup Paracetamolare: hypersensitivity to drug components; liver and renal failure, congenital hyperbilirubinemia (Zhilbera, Dubbi-Johnson syndrome, rotor), rare hereditary fructose intolerance (deficiency of glucose-6-phosphatehydrogenase), blood disease (pronounced anemia, leukopenia); Age up to 2 months.

Paracetamol for teenagers

Here is a reference chart that you can use when you need to give a child this painful pain. Teens and adult children get a dose of paracetamol. Therefore, for adolescents you can give a tablet of 200 mg. Make sure the dosage corresponds to the appointment of the doctor to avoid overdose.

Paracetamol side effects

Side effects are rare, but when they do it, they may need medical care. Flushing, changing blood pressure and increasing heart rate. Paracetamol overdose may result in damage to the liver and kidney, which can be fatal in some cases.

  • Allergic reaction, such as rash or swelling.
  • Long-term effects of blood disorders, such as leukopenia and thrombocytopenia.
In addition to this, if you see any unusual symptoms in a child after using paracetamol, immediately consult a doctor.

Interaction with other drugs:
A drug Paracetamolit should not be used simultaneously with other drugs, which include paracetamol in order not to exceed the maximum daose dose of paracetamol.
Preparations that induce liver microsomal enzymes (including barbiturates, phenytoin, carbamazepine, prison, other anticonvulsants, tricyclic antidepressants, oral contraceptives, viscotic drugs), ethanol: It is possible to strengthen the toxic effect of paracetamol on the liver due to increasing the degree of conversion of the drug on Hepatotoxic metabolites, especially when applying high doses of paracetamol.
Barbiturates: decrease in paracetamol antipyretic effect.
Do not apply simultaneously with ethanol and other drugs containing ethanol.
Probenecid, propanolol: It is possible to increase the action of paracetamol.
Lixisianatid: It is possible to reduce paracetamol absorption when applying it through
1-4 hours after applying Lixistatid.
Chloramphenicol: Its toxicity, since the half-life of chloramphenicol is extended and its concentration in the blood plasma increases.
Metoklopramide, Domperidon: It is possible to increase the rate of paracetamol absorption.
Cholestramine: It is possible to reduce the speed of paracetamol absorption.
Warfarin, Other Kumarins: It is possible to enhance the anticoagulant effect with an increase in the risk of bleeding when using high doses of paracetamol for several days; Recommended regular monitoring of the international normalized relationship (MNO); Oral doses of paracetamol have no significant effect. If necessary, the dose of intake of anticoagulant should be corrected in the treatment of paracetamol.
Difluorize and other NSAIDs: the level of serum paracetamol increases, which increases the risk of hepatotoxicity and nephrotoxicity.
Isoniazide, Rifampicin, other hepatotoxic means: raising the risk of developing hepatotoxic syndrome.
Diuretics: paracetamol reduces their effectiveness.
Antiviral preparations: Regular use of paracetamol may reduce the metabolism of zidovudine (increased risk of neutropenia).
Interaction with diagnostic tests: Paracetamol can affect the results of determination of uric acid in the blood using a method with phosphorovolphramic acid and determining glucose in blood oxidase-peroxidase method.

Precautions to prevent paracetamol poisoning

Since paracetamol is one of the most commonly used drugs at home, the likelihood of overdose or poisoning is high, if you do not pay attention to the dose. Here are some of the precaution that you must take to avoid accidental overdose.

Do not mix paracetamol with ibuprofen or any other drug if it is not specifically recommended by the doctor. Since we still have paracetamol at home, we can get outdated medicines. Always check the expiration date on the tape or bottle before using it. Do not remove the tablet from the sheet or do not pour the syrup into a spoon or a cup until the child takes the medicine. Always leave Paracetamol tablets in an inaccessible place for children. To avoid confusion, always celebrate the doses of paracetamol that give the child during the day. Between doses there should be a distance of at least six hours. Do not give more than four doses per day. If your child or painful fever deteriorates or does not decrease, even after 48 hours of paracetamol reception immediately consult a doctor. If the validity period is not displayed or not mentioned, do not use it. . Information about the patient from the Swiss medicine collection®.

Overdose:
In case of overdose of syrup Paracetamolclinical and biochemical signs of liver damage are manifested in 12 - 24 hours. Biochemical Signs: Increased dehydrogenase activity, liver transaminases, increasing bilirubin concentration, decrease in prothrombin level. Clinical symptoms: anorexia, nausea, vomiting, abdominal pain, skin pallor, hepatocellular insufficiency, liver necrosis, metabolic acidosis, encephalopathy, cardiac arrhythmia and pancreatitis. The lesion of the liver is possible in adults who took 10 g and more paracetamol, and in children who accepted more than 150 mg / kg.
Treatment: urgent hospitalization, stomach wash, provoking vomiting, receiving activated carbon, administration of N-acetylcysteine \u200b\u200bintravenously or methionine orally, symptomatic therapy.

What is Dafalgan and when is it used?

The rash of syrup Dafalgan contains as an active ingredient paracetamol. This substance soothes pain and reduces fever. Children's syrup Dafalgan is used for short-term treatment of headaches, dental pain, pain pain and ligaments, pain pain, pain during menstruation, pain as a result of wounds, pain associated with chills and fever.

What should be considered separately from treatment?

Like all antipyrtic and analgesics, Dafalgan should not take more than 5 days or more than 3 days in case of fever without a doctor's prescription. The maximum duration of continuous use of children up to 12 years without consultation with the doctor is 3 days.

Storage conditions:
Store at temperatures up to 25 ° C in an inaccessible place for children.

Release form:
Paracetamol syrup for children - Syrup. 60 ml or 90 ml in a jar with a dosing cup in a pack.

Structure:
Active substance ParaceTamol; N- (4-hydroxyphenyl) acetamide; 5 ml of syrup contains paracetamol 120 mg;
auxiliary substances: sorbitol solution that is not crystallized (E 420); Glycerin, Propylene glycol, Sakharin Sodium, Potassium Sorbat, Aspartame (E 951), Aromatizer "Orange ASE 896", Azocracy "Yellow Sunset FCF" (E 110), purified water.

High temperature or aggravation of the overall state of children requires timely medical advice. To avoid the risk of overdose, make sure that other injected medicines do not contain paracetamol. It should also be noted that the long-term consumption of analgesics can contribute to the preservation of headaches.

When Dafalgan should not be taken?

Long-term use of analgesics, especially in combination, can cause long-term deterioration of kidney function with risk of renal failure. Dafalgan can not be used in the following cases. Hypersensitivity to the active ingredient of paracetamol or any other ingredient. Hypersensitivity of this type manifests itself, for example, such signs as: asthma, respiratory distress, circulatory disorders, skin swelling and mucous membranes or rash; Health function of the hepatic function.

What precautions should be taken when making Dafalgan

Precautions should also be taken with the simultaneous use of drugs consisting of active ingredients, such as chloramphenicol, salicylamide or phenobarbital.

Additionally:
Do not exceed the recommended dose. If signs of the disease persist or worsen, it is necessary to consult with the doctor.
With caution, prescribe patients with impaired liver and kidney function, benign hyperbilirubineia and diabetes mellitus.
It is not recommended to apply simultaneously with other preparations containing paracetamol through the ability to overdose.
Reception of the drug may affect the results of uric acid tests (by the use of phosphorovolframic acid) and blood glucose (oxidase-peroxidase method). The drug may cause a minor laxative effect.
Children.
The drug is intended for use in children aged 2 months.



The composition of paracetamol in suspension

100 ml of the drug contains

100 ml drugsң ұұRamanda

Paracetamol active substance

paracetamol 2.4 g

2.4 g paracetamol

Auxiliary substances in paracetamol

methyl Parohydroxibenzoate, sorbitol liquid, glycerol, Ksanthanovaya gum, strawberry flavoring, sucrose, water purified to 100 ml

Is it possible to take Dafalgan during pregnancy or breastfeeding?

This drug is intended for children. If Dafalgan's syrup is accepted with young or adult women, the following should be considered. As a precautionary measure, it is recommended to stop taking drugs, if possible during pregnancy and breastfeeding, or seek advice to your doctor, pharmacist or pharmacist.

The data available today does not indicate the risk for the child if the active component of paracetamol is used for short-term treatment and in the specified dosage. Although paracetamol passes into breast milk, breastfeeding is allowed.

methyl Parohydroxybenzoate, Sodyқ Sorbitol, Gliecel, Xanthan Syyry, ұұlpunai Khostendіrgіshі, Sakharoza, 100 ml Diіn Tazartylғan Su

Indications for the use of paracetamol suspension

  • as an antipyretic agent for colds, flu, children's infectious diseases (chickenpox, rubella, cough, scarletin and epidemic vapotitis)
  • as an anesthetics in teething, dental pain, pain in the ears when otitis, sore throat
  • tyuyu Aurularynda, Tұmuda, Balalardaғa Jұұpals Aurulard (Zhelyashekte, Kyzamyқta, KөkzhөTeDe Scarlatina Zhene Epidemilaskyқ Parotitis Svinkada) Susta Tasіrtіn dәrі retіnde
  • tіs Zhғhanda, Tis Auyrғanda, otitit Kezinde ұұlak Auyrғanda, Tamak Ayirғanda Auyruday Basatin Dәrі Retіnde

Paracetamol contraindications in suspension

  • hypersensitivity to paracetamol or other components of the drug
  • pronounced disorders of liver and kidney functions
  • genetic absence of glucose-6-phosphate dehydrogenase
  • newborn period (up to 2 months)
  • the drug does not apply simultaneously with anticonvulsants
  • paracetamolғa Nememe Preparathsң Basқa Componentter Asian Satіmtadyқ
  • bauyr Men Bүyr Kyzmetіnі қңyn Bұzlulalaras
  • thrombocytopenia, leukopenia, agranulocytosis
  • glucose-6-phosphate dehydrogenasesң Geneticaly Boloouau
  • zhaңa Tuғa SәBiler (2 AIғa Diіngі)
  • preparatives ұұrysuғa қрасы дәріlerman bіr mezgіldj олoldanuғa bolmayda

Side effects of paracetamol suspension

  • nausea, vomiting, abdominal pain
  • allergic reactions in the form of skin rash, itching, urticaria, swelling

Seldom

To open the bottle, press the cap and rotate it simultaneously in the direction of the arrow on the top of the cover. Keep a measuring spoon in a vertical dose measurement position. Children's syrup Dafalgan should not be administered to children under the age of 6 months and should not be prescribed more often than indicated.

Children from 7 to 10 kg: For one dose, fill the measuring spoon to the graduation corresponding to the mass of the body, wait 6-8 hours until the next dose. The maximum daily dose, divided by 3 doses, is 500 mg of paracetamol. Children from 10 to 15 kg: for one dose, fill the measuring spoon until the end of the graduation corresponding to the mass of the body, wait 6-8 hours until the next dose. The maximum daily dose, divided by 3 doses, is 750 mg of paracetamol.

  • hepatasic and nephrotoxic effect
  • zhүr Ainau, ұұsu, іstің Auyru
  • tERIA BөTPESІ, қSHU, ESKEM, QUINKA ISINIA TүRіNEGI Allergy

Sary

  • hemolytical anemia, Aplastylas Anemia, Methemoglobinemia, Pancitopenia
  • hepatowytte Zhene Nephloytty әster

Special instructions for use

Carefully: Violations of liver and kidney functions, benign hyperbilirubinemia (incl. Zhilbera syndrome), viral hepatitis, diabetes mellitus.

Children aged from 15 to 22 kg: Measure the amount required to configure by filling out 1 or 2 times a spoon until it reaches the gradations corresponding to the mass of the body, wait 6-8 hours before the next catch. The maximum daily dose, divided by 3 doses, is 900 mg of paracetamol.

Children from 22 to 30 kg: Measure the amount required to configure, twice filling the spoon until the graduation corresponds to the weight of the body, wait 6-8 hours until the next dose. Children from 30 to 40 kg: Measure the amount required to configure by filling 2 or 3 times the spoon until the gradations correspond to the weight of the body, wait 6-8 hours until the next catch.

Application in children aged 2 months to 3 months It is possible only to appoint a pediatrician doctor as an antipyretic agent.

The simultaneous use of paracetamol with other paracetamol-containing drugs should be avoided, since this may cause paracetamol overdose. With the ongoing feverish syndrome on the background of the use of paracetamol for more than 3 days and pain syndrome more than 5 days, a doctor consultation is required. When taking the drug, the indicators of laboratory studies are distorted with the quantitative determination of glucose and uric acid in the plasma.

When taking the drug for more than 7 days, the picture of the peripheral blood and the functional state of the liver is required. The suspension contains 0.04 X 1 ml sucrose, which should be considered when treating patients with diabetes mellitus.

Saktyқpen: Bauyr Men Bүyr Kyzmetterіnің Bұzilulary, tersіz HyperbilirubiniMiyar (Sonsions Ішіnde Zhilbert Syndromes), Virustyk Hepatitis, Kunti Diabeeti. 2 Aidan 3Ayғa Diіngі Balalard Tech Pediatrician DәRigerdің Taғyyndaui Boyyins Susta Tүsіretіn Dәrі Retіnde Koldanuғa Bolada. Paracetamoldң ңұRamanda Paracetamol Bar Basқa Preparattarman Bir Mesgіld Kerdanyluyn Baldirmaau Kerk, өytkenі Bұl Paracetamoldiң artyқ Dosalauyn Tudeyruy Mүmkіn. Paracetamold ұұққa convicted Syndromynda 3 Kүnen Artyқ Zhen Auyru Sindromynda 5 Kүnen Artyқ қAbyldau Ajasanda DәRіgerdің Kejesі ажет. Preparatives Abyldғanda Plasma Glucose Men Neshek Kyshқylyn Sandyқna AnyaTaudaғa Zhorthanalyқ Zhortteulerdің Kөrsetkisteri Burmalalanada. Preparatives 7 Kүnnen Arttyқ Abyldғanda Shetkergі ан ан өрінісін жәна Буюрдиң фоторина слека зағдайн BAқLAU қат. Suspensions ң 1 ml ұұramyand 0.04 HB Sakharoza Bar, Mұna Kunti Diabetes Bar Emedehewsiterdі Emedegende Esteru Kerek.

Dosage and method of application

Inside, before meals in an undiluted form, drinking with water, 3-4 times a day with an interval of 4-6 hours. Before use, the contents of the bottle should be good enough. For convenience and dosing accuracy, we recommend using a double-sided spoon: a large spoon contains 5 ml (120 mg of paracetamol), small - 2.5 ml (60 mg of paracetamol).

The dose of the drug depends on the age and mass of the body of the child. A single dose of the drug is 10-15 mg / kg body weight. Maximum Su-accurate dose - no more than 60 mg / kg body weight of the child.

Depending on age, the drug is prescribed in the following one-time doses:

in 2- 3 months - about 2 ml of suspension only by appointment of a doctor (about 50 mg of paracetamol),


from 3 months to 1 year
- 2.5-5 ml of suspension (1/2 - 1 tsp) (60-120 mg of paracetamol),


from 1 year to 6 years
- 5-10 ml of suspension (1 - 2 tsp) (120-240 mg of paracetamol),


from 6 to 14 years
- 10-20 ml of suspension (2 - 4 tsp) (240-480 mg of paracetamol).

The maximum duration of treatment without a consultation of a doctor no more than 3 days as an antipyretic agent and no more than 5 days - as an anesthetic. Continuation of treatment with the drug after consulting a doctor.

Ішка, Ас ішкенга Дінн Сұyyltylmān Kүyіnde, Tәulіgіn 3-4 retro 4-6 Satuat Aralқpen Sumen Ішіp қаbydide. Piidalanar Aldinda ұұtynyaң Ішіndegіsіn zhuckylap Шайқау керек. Kolayla Zhәn Dlam Doszalau үShіn Ekіjaқty қasyuktya Paidalanda ұSynamy: үlken асақта 5 ml (120 mg paracetamol), kіshіsіnde - 2.5 ml (60 mg paracetamol). Preparativesң Dozasa Balaniң Zhasa Menny Salmaғyna Baylanists. Preparativesң Bіr Rettіk Dossa Dena Salmaғyna 10-15 mg / kg ұұride. Eң Joғarғy Tәulіktіk Dozasa - Balaniң Den, Salmaғyna 60 mg / kg aspaida. Jas Shamasyna Baylanists Taperattes of Minta Bіr Rettіk Dosalada Taғynda:

2- 3 Ida -2 ml Zhuyқ Suspension Tech DәRіgerdің Taғayyndau Boyyins (50 mg Zhuyқ Paracetamol),

Paracetamold Barbittarman, Dipheninmen, ұұrysuғa қрасы DәRILERMEN, Rifampicinmen, Butadionman Piidalanғanda Hepatowytty әSerіnің қапі Artuy Mүmkіn. Levomycetinman Bіr Mesgilde Kabyldanғanda (chloramphenicolman) Sosysya-Uyuttylaғi Artuy Mүmkіn. Warfarin Men Kumarinnің Basқa Tuyandlarynnyң Anticoagulanttyқ әsserі Paracetamold ұZққT ұDaiy қAbydau Ayasanda KүаSYYI MүMKIN, BұL анAN KETU қапін arttyrada.

Paracetamol overdose in suspension

Symptoms: During the first 24 hours after the reception - the pallor of the skin, nausea, vomiting, anorexia, abdominal pain; Violation of glucose metabolism, metabolic acidosis. Symptoms of the liver function may appear 12-48 hours after overdose. With severe overdose - liver failure with progressive encephalopathy, coma, death; acute renal failure with tubular necrosis (incl. in the absence of severe liver damage); arrhythmia, pancreatitis.


Treatment
: Stomach washing no later than 4 hours after poisoning, reception of the adsorbent (activated carbon). The introduction of Donders of SH-groups and precursors of the synthesis of glutathione - methionine after 8-9 h after overdose and acetylcysteine \u200b\u200b- after 12 hours. The need to carry out additional therapeutic measures (the further administration of methionine, intravenous administration of acetylcysteine) is determined depending on the concentration of paracetamol in the blood, and Also on the time passed after its reception.

Belg_ler: Abildaғannan Keyin Bastapki 24 Saduat Ішіnde - Teri Zhabyndarynyaң Basaruy, Zhүre Ainaui, ұұSu, Anorexia, Abdomaldi Ayuru; Glucose metabolism of Błziluy, metabolic acidosis. Bauyr Kyzmetі Bұziluynyaң Belgіlerі Artyқ Doszalanannan Keiіn 12-48 Sattan Social Pide Boluy Mүmkіn. Auyre Artyқ Dosalanuda - Encephalopathyң үDuymen Bauyr Zhetkilіlіzdіgі, coma, өlu; Tubularly Non-Simben Bүikektің Zheved Zhetkіlіksіdіgі (Sons of Ішіnde Baurydaң Auyre Zuzdanuy Boloғanda); arrhythmia, pancreatitis.

EMI: Ulanғannan Keiіn 4 Satuatan Kesіktіrmey Askazandda Schau, Adsorbent қAbyldau (Belsendіlendіrilgen Kөmіr). SH Tobyon Donatorlaryn Glutathione Synthesis іzasharlarn Ungіzu - Metionindi Artқ Doslandennan Keiіn 8-9 Salatan Society Acetylcisteindi - 12 Salatan San. ҚShomsha Emda Sharalaryn Zhrgіz Kazhettіlіgі (methionindі әrі rai ngіzu, acetylcisteindі kөktamir Ішінн Енгізизіза парацетамотаң анадағa concentrationsana, Sondai-aқ абладағанна кайнні өткан Уқтқа Байланиста Аняқтары.

Pharmacological properties

Pharmacokinetics

Absorption - high, the time to achieve maximum concentration (TCMAX) - 0.5-2 hours; Maximum concentration (Cmax) - 5-20 μg / ml. Communication with plasma proteins - 15%. Penetrates the hematorencephalic barrier. The therapeutically effective concentration of paracetamol in plasma is achieved when it is prescribed at a dose of 10-15 mg / kg.

Metabolized in the liver (90-95%): 80% enters the reaction of conjugation with glucuronic acid and sulfates to form inactive metabolis; 17% is subjected to hydroxylation with the formation of 8 active metabolites, which are conjugated with glutathione with the formation of already inactive metabolites. With a lack of glutathione, these metabolites can block enzyme hepatocyte enzyme systems and cause them necrosis. In the metabolism of the drug also involved the CYP2E1 isoenzyme. Half-life (T1 / 2) - 1-4 h. Is excreted by the kidneys in the form of metabolites, mainly conjugates, only 3% unchanged.

Сіңіріluі - jo'ara, Ең jo'ara concentrations of the village of Waқtyta (TSMAX) - 0.5-2 Saғ; Eң joard concentrations (Cmax) - 5-20 μg / ml. Plasma Aқuyzdaryman Baylanssuy - 15%. Hematoensephaldyқ Bөget Arқyli өted. Paracetamol Plasmadғa TiMDI EMDIK Concentrations of Oya 10-15 mg / kg Do Zaғyyndaanda Zhetedi. Bauhydd metabolized (90-95%): Belsendі EMES Metabolitter TүZE FILLING GLUKURON қSHқYLY ZHUN SULFATTARMER 80% conjugation reaction TүSEDI; 17% Belsendі EMES Metabolitter TүZE Filtering glutathionement conjugationLanutyne 8 BelnedDI Metabolite TүZE FIREP Hydroxyldeng ұShyda. Glutathione Zhetkilіlіksіz Bolғanda, Bұl Metabolitter Hepatocytterdің FermentTіk Zhүyelerіn Bөheui Zhene Olddyң Negonzyn Tudeyuy Mүmkіn. Preparatives ң metabolism CYP2E1 isoenzyme de қatsysada. Roasted seed kese (T1 / 2) - 1-4 SAD. Bүyropen Metabolitter, Kөbrinesse Conjuigattar Tүrіnde, Tech 3% өzgerisіz Kүyde Shyғyadya.

Pharmacodynamics

Paracetamol - nonarcotic analgesic, blocks cyclooxygenase (COF) 1 and COF 2 mainly in the central nervous system, affecting the centers of pain and thermoregulation. In inflamed tissues, cellular periods are neutralized by the effect of paracetamol on the COW, which explains the almost complete absence of a negative effect on the water-salt exchange (sodium delay) and the mucous membrane of the gastrointestinal tract. Paracetamol has an antipyretic, painful effect.

Paracetamol - Esіrtkіlіk Yez Analgesic, Aura Ortalyқtara Mete TerrityTellerg әser ET Flying, Kөbіnes Ortalyқ Zhyka Zhyesіndegі 1 cyclooxygenasans (COW) Zhәn COF 2 Bөgadі. Кабанған Тіндерда гасушалақ peroxidazlar paracetamoldң COG-қAK әSERNIN Bateraptandada, Bұl Onda Su-Tұz Lyazuy (Sodium Men Sudeң Kіdіruі) Men Askazan-Ішки искинаң әSERSHATSA қABғYNA TERS әSerіnің Лүлдем ТүСінірілінійнінімей. Paracetamoldң Susta TүSіrtіn, Auyruda Basyatin әsterі bar.

Packaging and release form

100 ml in dark glass bottles with a screw neck, closed with aluminum caps with rolling thread and the first autopsy control. Every bottle with instructions for medical use in the state and Russian languages \u200b\u200band a spoon of dosage pharmacy are placed in pache-ka from cardboard.

100 ml-Den BұRondala Moines Bar, Oratable Omala Zhona Bіrіnshі Ashyluy Batylanatin Aluminum қalposhamen YouTendalғan Kңңgіrt Shynadan Jasalғan Bөtelkerere. Әр BөTemklenі Memlekettіk Zhәn Orun Tіldderindegі Medinada Koldanuluy Jөnіndegі nұsқaulқpen Жәна Perezalaғysh Dәrіkanalyқ қасақПен Біргека Картанна Жасалған Пәшкеге Salad.

To eliminate pathology, the best option will be consulting with a highly qualified specialist, since self-medication will only aggravate the situation, and possibly lead to the emergence of other pathological conditions. Paracetamol does not eliminate the cause of the disease, but only has a symptomatic effect, having an antipyretic, anesthetic, minor anti-inflammatory actions.

Description of the drug

Paracetamol (Paracetamol) in tablets begins to act in the body after 15-25 minutes After entering the gastrointestinal tract. After receiving paracetamol, patients have a fairly pronounced antipyretic effect, small or mean painkillers and weakly pronounced anti-inflammatory action. There are a variety of forms of drug release, which are convenient for use and are most in demand in people of different age categories.

In pharmacies, you can purchase paracetamol in the following form:

  • pills;
  • capsules;
  • candles;
  • syrups;
  • suspension.
Each drug option has its advantages for the treatment of adults and children aged 3 months to 16 years. High degree The safety of the medication is characterized by the rapid excretion of the active substance from the body and the absence of the ability to accumulate in the tissues of internal organs. Paracetamol begins to act in 30 minutes, and after 4.5-5 hours it is full of its complete elimination. The main burden associated with the elimination of this chemical substance is 97% of the kidneys.

Antipyretic and anesthetic effects are saved by no more than 3-4 hours. .

Candles with paracetamol act more slowly, but prolongated in time. In this form, paracetamol knocks the temperature in an hour after setting the suppository, but it may be enough for all night, which is considered an advantage in comparison with other forms. Such the form of the drug Reduces the negative impact on the gastric mucosa and the liver, which can be subjected to pathological changes. Many pediatricians recommend using candles to children at night, which will prevent the temperature leap and not break the sleep of the child.

In what situations you can drink paracetamol?

Many people, using paracetamol, know how quickly the medicine can affect. The instructions for use are noted the following states and symptoms in which it is advisable to start receiving a given drug, namely.

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