For what causes ascorbic acid. Ascorbic acid solution for intravenous and intramuscular administration "Ozone

Vitamin C (ascorbic acid) is an essential substance for the normal functioning of the human body. Today ascorbinka remains best tool To strengthen immunity, especially in the seasons cold illness. In addition, this vitamin plays an important role in the process of developing collagen necessary to maintain a good condition, restoration of vessels, muscles, bone system, tissues and cells of the whole organism. At the same time human body Does not produce this item. Vitamin C comes only with food consumed.

All are known to the tablets, ascorbic acid dragee. Many of them took or take regularly to maintain health. Vitamin C ampoules are also used with therapeutic and prophylactic target. They, in particular, are prescribed when the body urgently requires additional introduction of this substance. It should be noted that the ampoules are also actively used in cosmetology.

When Vitamin C in ampoules is prescribed - application instructions for use, testimony from the drug, what? For complete information, we used the instructions for the preparation applied to the package. On its basis and drawn up this description. However, before applying the drug, be sure to familiarize yourself with the instructions independently.

Dosage form

Do you all use vitamin C in ampoules (testimony for use)?

As the instructions for use, the injection of vitamin C is prescribed under the states of the increased need for it:

Hypo-or avitaminosis;
- unbalanced or parenteral nutrition;
- with tense physical, mental work;
- women for lactation, as well as children during intensive growth (according to indications);
-Pacients, after the suffering diseases, the postoperative period;
- with disease with tuberculosis, quantity, burn disease, alcoholism, as well as smoking;
- with long-term supercooling of the body, the presence of fever, hyperthyroidism, as well as in chronic infections;
- in certain diseases of the gastrointestinal tract: persistent diarrhea, peptic ulcer, and also after resection of the small intestine and gastrectomy;
- with chronic intoxication with FE, idiopathic methemoglobinemia.

Also, the drug is prescribed with long stressful states, injuries, as well as during pregnancy, especially multiplying, occurring on the background of alcoholic, or drug addiction.

How to dispense vitamin C in ampoules (application)?

This drug appoints a doctor after a survey. He determines the course of treatment, as well as the method of administration (intravenously or intramuscularly). Usually durability is 10 days. But, if necessary, the course can be extended, however, no earlier than in a month.

One-time introduction of the solution should not exceed 200 mg. The daily dosage should not exceed 500 mg.

Application in cosmetology

Ascorbank solution in ampoules is also used to improve skin condition. With the external use of the solution in the form of masks, the complexion of the face is improved, minor wrinkles are reduced.

Regular application (2-3 times in a week) significantly improves the condition of the skin.
In addition, the vitamin C solution is used to improve the condition of the hair. Just add the contents of the ampoule to your shampoo, then wash your head as usual. With regular use, hair becomes strong, shiny, their elasticity increases.

What the drug "Vitamin C (in ampoules)" side effects?

For intravenous administration Care should be taken. Too fast process can cause dizziness, feeling fatigue. In the intolerance to the main component may occur allergic reactionsaccompanied by skin rash, skin hyperemia.

With long-term treatment with large doses of the drug "Vitamin C (in ampoules)" instructions for use also warns that signs of thrombocytosis, neutrophilic leukocytosis may be observed. Hyperprotrombinemia, erythroaction or hypokalemia may occur.

What are the means "vitamin C (in ampoules)" contraindications for use?

The drug is not prescribed under individual intolerance. Intravenous administration is contraindicated with sugar diabetes, thrombosis and thrombophlebitis, as well as with other states accompanied by increased blood coagulation, or a tendency to them.

Important!

When appointing increased doses Vitamin, necessarily accomplisions of the kidney work, a regular dimension is carried out arterial pressure. It is also necessary to monitor the level of glucose.

Patients with hypoacid (ancidal) states, the injection of hydrochloric acid with pepsin is prescribed before the injection course. This is necessary to exclude the risk of vitamin C destruction.

It must be remembered that in the treatment of this drug there is a distortion of some laboratory tests, namely: blood content of glucose, bilirubin, as well as transamamine and lactate dehydrogenase (LDH).

No doubt, vitamin C is an extremely important element for maintaining health, strengthening immune system. Nevertheless, it is necessary to understand that long-term reception, or high doses of this substance lead to hypervitaminosis, which is no less harmful to the body than hypovitaminosis. Therefore, use this drug only on the recommendation of the attending physician. Be healthy!

Different preparations are used in the treatment of respiratory diseases. In a complex with antimicrobial, vesseloring, mulitics and other means, patients prescribe medications that increase the resistance of the body and improving the flow of metabolic processes. Such is primarily ascorbic acid. All information about it, which is worth paying attention to is set out in the instructions for use.

Ascorbic acid (It is vitamin C) is a substance of the crystal structure as a white powder. It is well soluble in water, and in other liquids (alcohol, glycerin) is much worse. Powder has sour taste, stable in air. And here aqueous solutions When contacting oxygen is rapidly darker. For medical purposes, they are produced in ampoules with different concentrations. active substance (5 and 10%), volume of 1 or 2 ml.

Act

Vitamin C plays very important in exchange processes - the metabolism of proteins, fats and carbohydrates, synthesis of hormones, collagen, blood coagulation. Ascorbic acid has antioxidant properties and inhibits the selection of prostaglandins, helping to fight inflammation. It normalizes the permeability of the vascular wall and has antiallergic properties: accelerates the collapse of the histamine, inhibits the synthesis of anaphylaxia mediators. Medicinal substance Activates the enzyme liver system for detoxification of harmful substances in the body. Thanks to the improvement of tissue metabolism, wound healing and other damage is accelerated.

Vitamin is actively involved in immunological reactions at the local and systemic levels, increasing the resistance to infections. Ascorbic acid is capable of activating the formation of antibodies, antiviral protein (interferon), components of the complement system. Under its influence, the need for other vitamins (thiamine, tocopheropole, routine, folic and pantothenic acids) is reduced, the pancreas function is normalized and normalized thyroid glasses. All of the above makes a solution of ascorbic acid very popular with infectious diseases of the respiratory tract.

Vitamin C is very wide spectrum biological action. The effects of ascorbic acid are multifaceted and extremely important for the normal functioning of the body.

Distribution in the body

After parenteral administration, ascorbic acid 5% quickly penetrates blood with the achievement of maximum concentration. The fourth part binds to plasma proteins. Vitamin easily penetrates all the tissues of the body, especially ferrous. Metabolism mainly occurs in the liver. Excretion is carried out in various ways: through the kidneys, intestines, with then, female milk. The destruction of ascorbic acid is intensified during smoking and alcohol abuse.

Indications

Considering the comprehensive effect of the drug, its scope is very wide. Ascorbic acid in ampoules is prescribed at the following states:

  • Infectious diseases.
  • Various intoxication.
  • Hemorrhagic diathesis.
  • Bad healing wounds and ulcers.
  • Hypovitaminosis C.
  • Liver disease.
  • Bleeding.
  • Distrophic processes, etc.

The drug is widely used in patients with respiratory diseases. He speeds up recovery and warns the re-development of infection.

Application

Any medicine, including ascorbic acid, should be appointed by a doctor. Only a specialist may establish the feasibility of using the drug, determine the most appropriate dosage (how many percent and ampoules) and the optimal duration of treatment.

Method of reception


Ambula ascorbins are designed for parenteral administration, i.e., into the trafficking of the gastrointestinal tract. The solution is used with intramuscular or intravenous injections. One-time and daily dose depends on the content of vitamin in ampoule. 5% solution is introduced in 1-3 ml, and more concentrated - 1 ml. The instructions indicate the maximum dosages of the drug. Translated by a 10% solution, they correspond to 2 and 5 ampos (respectively, at once and a day).

Side effects

The use of acid ascorbin in ampoules is sometimes associated with a negative impact on the body. The synthesis of insulin and glycogen can be observed, which entails increasing blood glucose and its detection in the urine. In addition, the list of side effects in the injection injection of the drug includes:

  • Neriva-mental disorders (weakness and dizziness).
  • Allergic reactions (rash and redness of the skin).
  • Hematological disorders (raising platelets and neutrophils, reduction of red blood cells and prothrombin).
  • Local manifestations (soreness at the place of administration).

Changes in metabolism, in addition to glycemia and glucosuria, include fluid and sodium delay, potassium deficiency, enhanced glucocorticoid synthesis. The latter may cause an increase in blood pressure. If you enter intravenously large doses of ascorbins, that is, the risk of hemolysis of erythrocytes and interrupting pregnancy.

Despite the mass useful propertiesinherent ascorbic acid, the drug can also give side effects.

Restrictions

Even the necessary organism substance like vitamin C, with incorrect use, may entail undesirable consequences. Therefore, before its purpose it is necessary to take into account all limiting factors. Related diseases or probable reception of other medicines are all importance to ensure safe and effective treatment.

Contraindications

As the instruction manuals testifies, among absolute contraindications, there are only hypersensitivity to ascorbic acid and a tendency to arterial thrombosis. With caution, the medicine is used in patients with diabetes, hypertension, urolithiasis, glucose-6-phosphate dehydrogenase deficiency, hemolytic anemia. Injection forms Vitamin C during the baby tooling the child without extreme need is not prescribed. This is due to the lack of convincing data on the absence of unfavorable effect on the fruit.

Interaction

Ascorbic acid in ampoules can interact with other medicines. It increases the blood concentration of salicylate, estrogen, corticosteroids, some antibiotics (tetracycline, benzylpenicillin). The activity of norepinephrine during co-use with vitamin C increases, but the effects of anticoagulants (heparin, warfarin) are reduced. Under the influence of ascorbic acid, the absorption of iron preparations in the intestine is improved. The solution cannot be mixed in one syringe with other medicines.

Ascorbic acid for injection introduction - effective drugoperating complex. In respiratory diseases, it accelerates the patient's recovery and increases the organism resistance to infections. But the use of vitamin C must be coordinated with the attending physician.

Registration number: LP 002092-070815
Trade name of the drug: Ascorbic acid
International unpatient name: Ascorbic acid
Dosage form: intravenous solution intramuscular administration.

Composition per 1 ml:
Active substance:
Ascorbic acid - 50.0 mg - 100.0 mg
Excipients:
Sodium bicarbonate - 23.85 mg - 47.7 mg
Sodium Sulfite Anhydrous - 2.0 mg - 2.0 mg
Water for injection - up to 1.0 ml - up to 1.0 ml

Description:
Transparent colorless or slightly painted liquid

Pharmacotherapeutic Group: Vitamin.

ATH code: A11GA01

Pharmacological properties

Pharmacodynamics
Ascorbic acid (vitamin C) is not formed in the human body, and comes only with food.
Physiological functions: is a cofactor of some hydroxylation and amidation reactions - transfers electrons to enzymes, providing them with a reducing equivalent. Participates in the reactions of hydroxylation of proline and lysine residues pierced with the formation of hydroxyproline and hydroxylizin (post-transmission modification of collagen), oxidation of the side chains of lysine in proteins with the formation of hydroxytrimetalline (in the process of carnitine synthesis), oxidation folic acid to folinic, metabolism medicines In the liver microsomes and dopamine hydroxylation with the formation of norepinephrine.
Increases the activity of amidating enzymes involved in the processing of oxytocin, antidiuretic hormone and Holicystokinin. Participates in steroidogenesis in adrenal glands.
The main role in the fabric level is to participate in the synthesis of collagen, proteoglycans and other organic components of the inlet of the teeth, bones and endothelium of capillaries.

Pharmacokinetics
Communication with plasma proteins - 25%.
The plasma ascorbic acid concentration is approximately 10-20 μg / ml. Easily penetrates leukocytes, platelets, and then into all fabrics; The greatest concentration is achieved in ferruginous organs, leukocytes, liver and leather leakage; Penetrates the placenta.
The concentration of ascorbic acid in leukocytes and platelets is higher than in the erythrocytes and plasma. With deficit states, the concentration in leukocytes is declined later and more slowly and is considered as best criterion Deficiency estimates than plasma concentration.
Metabolized mainly in the liver into the deoxyaskorbic acid and further in oxaluacetic acid and ascorbate-2-sulfate.
Excreted by the kidneys, through the intestine, from then breast milk In the form of unchanged ascorbate and metabolites.
When prescribing high doses, the rate of excretion is sharply enhanced. Smoking and use of ethanol accelerate the destruction of ascorbic acid (transformation into inactive metabolites), sharply reducing reserves in the body.
Derived during hemodialysis.

Indications for use

Treatment of hypo- and avitaminosis C (if necessary to quickly replenish vitamin C and the impossibility of oral administration).
Apply for therapeutic purposes in all clinical situations related to the need for additional administration of ascorbic acid, including: parenteral nutrition, diseases of the gastrointestinal tract (persistent diarrhea, resection of the small intestine, peptic ulcer, gastrectomy), Addison disease.
In laboratory practice: for marking red blood cells (together with sodium chromat).

Contraindications

Hypersensitivity, as long use In large doses (more than 500 mg) - diabetes mellitus, hyperoxalura, nephrowolithiasis, hemochromatosis, thalassemia, glucose-6-phosphate dehydrogenase deficit.

Carefully

When applying in doses of less than 500 mg - diabetes mellitus, deficiency of glucose-6-phosphate dehydrogenase, hemochromatosis, sideroblastic anemia, thalassemia, hyperoxalura, nephrowolithiasis.

Application during pregnancy and during lactation

During pregnancy and during lactation, only in the event that the estimated benefit for the mother exceeds the potential risk to the fetus or child.
The minimum daily need for ascorbic acid in the II-III of trimesters of pregnancy is about 60 mg. The minimum daily need for lactation is 80 mg. Mother's diet containing an adequate amount of ascorbic acid is sufficient for preventing vitamin C shortage baby. During pregnancy, 300 mg per day of ascorbic acid should not be exceeded.
It should be borne in mind that the fruit can be adapted to high doses of ascorbic acid, which is taken by a pregnant woman, and, as a result, the newborn is possible the development of "Cancellation" syndrome.

Method of application and dose

Intramuscularly, intravenously (slow).
Adults - from 100 to 500 mg (2-10 ml of 5% solution) per day, with zing therapy - up to 1000 mg per day.
Children - from 100 to 300 mg (2-6 ml of 5% solution) per day, with zing therapy - up to 500 mg (10 ml of 5% solution) per day.
The duration of treatment depends on the nature and course of the disease.
For the marking of erythrocytes (together with sodium chromat) - 100 mg of ascorbic acid is injected into the bottle with sodium chromat.

Side effect

From Central nervous system: With rapid intravenous administration - dizziness, feeling of fatigue, with long-term use of large doses (more than 1 g) - headache, increasing the excitability of the central nervous system, insomnia.
From the urinary system: Moderate Pollakiuria (when applying a dose of more than 600 mg / day), with long-term use of large doses - hyperoxaluria, nephloolithiasis (oxalace calcium), damage to the glomerular kidney apparatus.
From side of cardio-vascular system: With prolonged use of large doses - reduction of permeability of capillaries (possibly deterioration of tissue trophics, an increase in blood pressure, hypercoagulation, the development of microangiopathy).
Allergic reactions: Skin rash, skin hyperemia.
Laboratory Indicators: Thrombocytosis, hyperprothrombinemia, erythroaction, neutrophilic leukocytosis, hypokalemia, glucosuria.
Local reactions: soreness at the site of intramuscular administration.
Others: With prolonged use of large doses (more than 1 g) - the oppression of the function of the induce apparatus of the pancreas (hyperglycemia, glucosuria), with intravenous administration - the threat of interrupting pregnancy (due to estrogenemia), the hemolysis of the erythrocytes.

Overdose

Symptoms: Nephloolithiasis, insomnia, irritability, hypoglycemia.
Treatment: Symptomatic, forced diuresis.

Interaction with other medicines

Increases the concentration in the blood of benzylpenicillin and tetracycline, in a dose of 1 g per day increases the bioavailability of ethinyl estradiol (including the part of oral contraceptives).
Improves suction in the intestines of iron preparations (translates the trivalent iron into a divalent); It can increase the excretion of iron while simultaneously use with deferoxamin.
Reduces the effectiveness of heparin, indirect anticoagulants.
With simultaneous use with acetylsalicylic acid The removal with urine ascorbic acid increases and the removal of acetylsalicylic acid is reduced.
Increases the risk of crystallurium development in the treatment of salicylate and sulfonamide short action, slows down with kidney acids, increases the removal of medicines having an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives.
Enhances the general clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.
The drugs of the quinoline series, calcium chloride, salicylates, glucocorticosteroid drugs during prolonged use are depleted by the reserves of ascorbic acid.
With simultaneous use reduces chronotropic action Isoprenaline.
With long-term use or use in high doses, it may interfere with the interaction of disulfiram and ethanol.
In high doses increases the removal of Mexyleletina by the kidneys.
Barbiturates and prison raises the removal of ascorbic acid with urine.
Reduces therapeutic action Antipsychotic drugs (neuroleptics) - derivatives of phenothiazine, canaline reabsorption of amphetamine and tricyclic antidepressants.
Pharmaceutically incompatible with aminoophylline, bleomycin, cefazolin, cefapyrin, chlordiazepoxide, estrogens, dexts, doxapprame, erythromycin, meticillin, nafcillin, benzylpenicillin, warfarin.

special instructions

Due to the stimulating effect of ascorbic acid on synthesis of corticosteroid hormones, it is necessary to monitor the function of adrenal glands and arterial pressure.
With long-term use of large doses, it is possible to invent the function of the inasurant apparatus of the pancreas, so in the process of treatment it must be regularly monitored. Patients S. increased content Iron in the body should apply ascorbic acid in minimal doses. High doses of ascorbic acid reinforce the excretion of oxalates, contributing to the formation of kidney stones.
Ascorbic acid, as a reducing agent, can distort the results of various laboratory tests (blood content and urine glucose, bilirubin, transaminase activity and lactate dehydrogenase).
Impact on the ability to driving vehicles and control mechanisms
During the period of treatment it is necessary to observe care when managing motor transport and occupation potentially hazardous species Activities requiring increased concentration and speed of psychomotor reactions due to the possible appearance of dizziness, feelings of fatigue and increase blood pressure.

Form release
The solution for intravenous and intramuscular administration is 50 mg / ml, 100 mg / ml.
1 ml or 2 ml in ampoules of colorless neutral glass Type I with a color ring of a break or with a color point and a notch or without a rings of a break, a color point and notches. One, two or three colored rings and / or two-dimensional barcodes, and / or alphanumeric encoding or without additional color rings, two-dimensional barcode, alpuning can be applied to the ampoules.
5 ampoules in the contour cellular packaging from the film of polyvinyl chloride and foil aluminum lacquered or polymer film or without foil and without a film. Or 5 ampoules in a pre-made form (tray) from cardboard with cells for styling ampoules.
1 or 2 contour cellular packages or cardboard trains, along with the instructions for use and scarifier or a knife, ampumen, or without a scarifier and an ampoule knife will interfere with cardboard packaging (pack).

Vitamin C is one of those components that are vital to the body. In large quantities, vitamin is contained in berries and citrus fruits. Pharmacies offer funds that resemble yellow pills with sourness from childhood. Their effectiveness is insignificant, in comparison with intramuscular administration. Ascorbic acid in ampoules instantly penetrates the circulatory system and useful substances are spread throughout the body.

The benefits of ascorbic acid

The substance accelerates the recovery and establishes the exchange processes of the human body. White or yellow tint powder has an acidic taste, remarkably dissolved in water. Thanks to the useful qualities of vitamin C, the drug is opposed various diseases and enhances protective functions. One portion of the means has the following impact:

  • strengthens the immune system;
  • cites the level of cholesterol;
  • reduces the likelihood of diseases of the respiratory system;
  • improves chemical composition blood due to the saturation of hemoglobin;
  • tones skin covering, promotes rapid cell regeneration.

When using ascorbic acid should be observed accurate dosageprescribed by the attending physician. Otherwise, a number of side effects will arise, including violation of functioning. digestive system and damage to gastric walls. Plus, an excessive amount of vitamin C loads the excretory system.

pharmachologic effect

The human body does not produce ascorbic acid independently, the required component gets along with food. It takes part in metabolic processes, restoration, oxidation, regeneration, normalization of blood clotting. The presence of vitamin C allows to exhibit stability before infections, as well as the substance establishes the permeability of capillaries, strengthens the vascular walls, reduces the lack of other vitamins.

The tool exhibits an antioxidant effect that provides hydrogen transportation for the absorption of glucose and the successful implementation of important biochemical processes, such as the synthesis of collagen elements and hormones from the steroid group.

Ascorbic acid with intramuscular administration is combined with plasma proteins, after 4 hours after entering the blood, the concentration of the substance reaches its maximum. The component quickly penetrates the tissue along with platelets and leukocytes, accumulating in the organs. Suction is carried out by B. thin intestineswhere Vitamin is transformed into dehydroasorbinic acid.

Intestine and kidneys are responsible for the output of metabolites, some of the body disappears from the organism and then both breast milk. It is important to take into account that spirits and tobacco products Provocate the change in ascorbic acid. Reserves of substances in the body are reduced due to its transformation into inactive type metabolites.

When to use

Experts recommend to increase the dose of ascorbic acid naturally, that is, through food, but sometimes it is impossible to do it, especially in the winter season. The introduction of ascorbic acid intravenously and intramuscularly is assigned in such cases:

  • the elimination of avitaminosis and hypovitaminosis of ascorbic acid, when oral use is impossible, and the need for an urgent replenishment of the substance is present;
  • with problems with the functioning of the digestive system;
  • in case of chemical poisoning by gaseous substances, in this case an ascorbinka normalizes oxidation and restores the inner medium of the body, which is important when removing toxic elements.

These problems need to contact medical institutionwhere a specialist is individual plan Treatment based on the results of diagnostic measures.

Indications for use

Attention should be paid to the first symptoms of hypovitaminosis, which manifest themselves as paleting the skin, disorders of regeneration, weakness, insomnia, weakened immunity, the bleeding of the gums. Vitamin C in ampoules for injection is used in the following situations:

  • long-term supercooling of the body;
  • irrational nutrition;
  • in the presence of dangerous diseases, such as qing and tuberculosis;
  • prolonged physical and mental stress;
  • recovery period after surgical intervention or protracted treatment;
  • therapy against dependence on alcohol and tobacco products;
  • abundant bleeding;
  • intoxication of the body;
  • liver disease;
  • hemorrhagic diathesis;
  • problems with the functioning of respiratory organs;
  • dystrophy.

In each case, the dosage and reception regularity is determined individually. Sometimes you can get rid oral administrationBut in certain cases, injections are prescribed.

special instructions

A continuous lack of ascorbic acid causes irreversible changes in the body. These include:

  • the emergence of secondary infectious diseases;
  • excessive mobility or loss of teeth;
  • the tendency of bones to fractures;
  • problems with the work of digestive, cardiovascular, excretory systems;
  • abundant bleeding;
  • pain sensations in muscles and joints, which significantly limits mobility.

Clinical manifestations of the deficit lead to the appointment of vitamin C injections to avoid negative consequences, with injections, strict dosage and regularity should be observed. Ascorbic acid is introduced into the blood of the stake (for 2-3 minutes) or drip (25 drops per minute). In the first case, the basis of the means is saline (0.9%) or a solution of glucose (5%), in an amount of 50-100 ml. Droppers with ascorbic acid are used in serious diseases.

Before intramuscular use, the drug is heated to ambient temperature (about 23 degrees), then filled with a syringe and introduced a working solution from ascorbic acid directly into muscle tissue. For injections, a solution of 5% is intended. Adults are assigned to the reception of vitamin three times a day of 1-5 ml. IN childhood Dose decreases to 1 ml. The treatment plan directly depends on the stage of illness and the condition of the body.

Due to the fact that ascorbic acid leads to the development of corticosteroid hormones, the likelihood of the formation of congregations in the kidneys increases. That is why therapy is carried out with regular diagnosis of adrenal glands, kidneys and pressure in blood system. With an excessive level of iron in the body, it is necessary to approach with extreme caution. An increase in the content of vitamin C leads to a violation of the pancreas.

Side effects

The use of vitamin C in ampoules requires compliance with some rules. As a rule, ascorbic acid is perfectly perceived by the body, but under a number of factors, side effects arise, which include:

  1. Lost and dizziness, which is a consequence of the rapid administration of a solution of ascorbic acid.
  2. Pain in the zone of intramuscular injection.
  3. Excessive excitability and frequent migraines in overdose.
  4. Increased arterial pressure due to capillary permeability.
  5. Allergic reactions with individual intolerance of the component.
  6. Thrombocytosis, leukocytosis and glucosuria.
  7. Lack of adrenal cortex.

With any of these factors, it is necessary to stop receiving the means and consult with the attending physician. Otherwise, severe complications and secondary diseases are developing. Before pricking vitamin C, it is necessary to be convinced of the absence of individual intolerance.

Is an overdose possible?

Overdose is a consequence of a negligent attitude towards the treatment of ascorbic acid. This often occurs when the patient moves to independent or home administration of injections. Therefore, patients are recommended not to abandon therapy in outpatient conditions. Signs of dose exceeding are:

  • hyperglycemia;
  • arterial hypertension;
  • thromboembolia;
  • elevated blood sugar;
  • the formation of concrections.

These problems arise not only in overdose, but also in the case of long-term treatment. In any case, it is necessary to stop receiving the funds and tell the doctor about the problems that have arisen.

Compatibility with other drugs

Ascorbic acid is not recommended to be used with preparations, which in its composition have folic acid, iron, vitamin B12. Their combination leads to undesirable consequences, and in long-term therapy develop serious side effects and diseases.

Contraindications

Ascorbic acid in the form of injections, like another drug, has some contraindications. According to the instructions, their number includes:

  • individual intolerance to acid;
  • diabetes;
  • conditions in the excretory system;
  • blood coagulation disorders;
  • pregnancy and lactation;
  • thrombophlebitis or a tendency to the formation of thromboms.

Ascorbic acid is an organic compound with related ties with such a matter as glucose. Ascorbic acid is one of the main acid elements in the human body. The functional abilities of ascorbic acid are aimed at reducing processes and establishing the operation of metabolic processes.

The main active element in the composition of ascorbic acid is vitamin C, which is necessary vitamin To support the body and immunity at a good level. Therefore, this acid is often referred to as vitamin C. Ascorbic acid is often found in nature, it is contained in many fruits and in some vegetables.

Ascorbic acid according to its properties is a white or light yellow powder, which has a sour taste. In addition, this type of acid is very well soluble in liquids, giving an acidic shade of the water in the water in which it will be dissolved.

In 1 932, when Vitamin C was found for the first time, huge plans were imposed on his share. But experiments have shown that with the help of ascorbic acid, you can only maintain the human body and prevent many clinical cases of various diseases.

Who and when is it necessary to use ascorbic acid?

The main cases of ascorbic acid use:

  • Usually in ascorbic acid, people who have received carbon monoxide poisoning or other harmful gaseous substances are needed. In severe poisoning, ascorbic acid normalizes the processes associated with oxidation and restores the normal medium in the human body. In cases of poisoning of the dose of ascorbic acid, it can be up to 0.25 ml per 1 kg of weight.
  • The lack of vitamins during the change of seasons is also a reason for the use of ascorbic acid. It can be like drug TreatmentSo containing vitamin C fruits and vegetables that need to be added to the casual menu. This will help strengthen the immunity and easier to transfer such a period.
  • Pregnancy. During pregnancy, many girls experience a lack of vitamin C. By appointment of a doctor, the use of ascorbic acid is recommended. On average, a pregnant woman should receive more than 30% ascorbic acid than before pregnancy.
  • Smoking. As in charge of carbon monoxide, smoking people need an increased dose of vitamin C. This is necessary for the reduction of the acid medium in the body.

The benefits of ascorbic acid

The benefits of ascorbic acid can be judged by the symptoms of its lack. The lack of due amount of vitamin C can be seen at the following symptoms:

  • Skin pallor;
  • Imminent immunity;
  • Increased tightening time wounds;
  • Bleeding gums, teeth whitness;
  • Common malaise;
  • Anxiety and bad sleep;
  • Pain B. lower limbs (especially heels and feet)

To ensure that these symptoms do not appear, and ascorbic acid is valid. It will also be useful if available.

Harm ascorbic acid

Askorbinic acid qualitative preparation itself is safe. But this does not mean that you can eat ascorbing packs. A number of contraindications on this drug are still available. The basis of problems in overdose of vitamin C, in which there is also nothing terrible, but it is only for healthy peopleBut those who have problems with the stomach (gastritis, ulcers) use of such an acid can cause a number of complications.

Overdose ascorbic acid

The overabent acid is badly affected by the state of the stomach and digestive tract, Driving a stomach wall. This is an actual problem for people with disorder of the digestive system.

If the overdose still happened, then some consequences will be useful to know it now.

For example, pregnant women can break or exit substance controls, which can lead the mother and fetus organism to certain problems. The future child can become more susceptible to allergies, and the mother will have problems with the stomach.

Side effects of consumption ascorbic acid

Vitamin C, like all ascorbic acid, is water-soluble, and this means that if you take it more than the body it is necessary, then the excess will simply take place. But it can cause a stomach disorder, pain in the abdomen, diarrhea or convulsions, if you take too much. If an additional amount of vitamin C is planned, then the dose should be increased gradually over time to assess the possible side effects.

What drugs are not compatible with the reception of ascorbic acid?

Ascorbic acid should not be used in an amount with preparations containing a large amount of iron, caffeine, vitamin B12, folic acid. More complete and detailed information on compatibility is better to read in annotations, it is in each package.

What should be aware of the use of ascorbic acid?

The use of ascorbic acid depends on specific factors. First, you need a medical advice, in the second you need to buy ascorbic acid in tablets or liquid in pharmacies of a large network, it is very important because the fake drugs are increasingly falling across the counters.

Use this drug is better after eating. Doses for holding preventive treatment Avitaminosis is 50-100 mg for an adult person per day. For children, the norm is 25-75 mg. Of course, this dose depends on the mass of the human body and its age. Larger doses are used in diseases during intensive treatment with the drug.

Using ascorbic acid, it should be correct, it is necessary to observe the desired dosage, avoid incompatible drugs and consult with the doctor. Unfortunately, many people think that vitamins are not superfluous, but in fact, excess vitamins often exposes the body with stress and makes it vulnerable to diseases. Often excess vitamins are more harmful than their disadvantage, although it is less common.

The fact that during smoking the need for vitamin C increases - I will keep in mind. For smoke. Thanks for the info!

The main thing here is to follow the children so that they do not eat many of these vitamins. I remember in my childhood, I loved thesety vitamins himself and could eat them, if it were not for Mom.

Ascorbic acid, of course, is made in any form and in different doses, it also needs to be considered, giving it to children.

This article published a lot of controversial statements. For example, pregnant women are usually not prescribed ascorbic acid, it can cause bleeding. The required amount of vitamin C is obtained from fruits and vegetables, which must prevail in its diet.

Where does such information come from that ascorbic acid can cause bleeding during pregnancy? In the right doses, it should not bring harm. Maybe you confused it with acetylsalicylic acid (aspirin), which is more likely to cause such a problem?

Good day!

Oh, please tell me. Literally an hour ago I ate 8pcs (100mg in 1Tab. Napdano) ascorbine, I didn't even think that they could be harmful when we take. I have 10 obush. We have been experiencing more precisely 9.5). Can drink more water or something to fit. I will not eat them anymore at all, I don't know today at the pharmacy came and bought and buried the machine

Do not worry. Although the recommended daily dose of vitamin C (ascorbic acid) for women is 75 mg, but the upper permissible limit is considered to be 2000 mg. These are at least 20 tablets containing 100 mg of ascorbic acid (if not to take into account eaten products containing vitamin C). And many tablets and at all contain only 25-50 mg. After that, the permissible limit can manifest side effects (nausea, diarrhea). And so everything is superfluous simply with urine.

But with extreme caution during pregnancy, ascorbic acid should be taken in the presence of risk of rooting blood pressure, and some rare genetic diseases.

Therefore, do not worry. But in the future do not take more norm. But it is better to choose natural sources of this vitamin - a large orange, a glass of strawberries, a red pepper ...

Health to you and your future kid

After a heavy workout, severe oxygen starvation, light numbers and blood as if stopped carrying oxygen. He strongly suffered to the floor of a fainting condition, and somehow in the showroom lay ascorbic acid dragee. Somewhere I read that AK restores the body, in short put two dragees in the mouth and, about a miracle, after 15 minutes I could easily breathe, the lungs earned the oxygen again, as a hand shot.

Hello in the morning after the lightweight breakfast went to the hospital and I Cole Ferrum Lek (because anemia) and intravenously ascorb. Cycling after him immediately became worse than nausea, vomiting, dizziness. It was the third day. This happens? 21med.Berenity

I apologize, in fact, the situation is acute and requiring an urgent answer. But now I flew myself and almost never for the PC week. Here are the words of the doctor (good therapist, site consultant):

Ascorbic acid with glucose (Ascorbic Acid With Glucose)

Active substance

Pharmacological group

Nonological Classification (ICD-10)

Composition and form of release

1 ampoule with a lyophilized powder for the preparation of an injection solution contains ascorbic acid 0.05 g, in a set with water for injections, in ampoules 2 ml; In packing 5 sets.

pharmachologic effect

Participates in the regulation of carbohydrate metabolism of redox processes, blood coagulation, permeability of capillaries, tissue regeneration, synthesis of steroid hormones, collagen, punctured.

Indications of the drug ascorbic acid with glucose

Avitaminosis and hypovitaminosis C; hemorrhagic diathesis, bleeding (nose, pulmonary, hepatic, uterine, caused by radial disease); an overdose of anticoagulants; infectious diseases and intoxication; Addison disease, nephropathy of pregnant women; sluggishly healing wounds and bone fractures; dystrophy; Mental and physical tension.

Side effects

Understanding the function of the inusular apparatus of the pancreas (with long-term use).

Method of application and dose

In / m, in / in, before administration, lyophilized powder is dissolved in 1-2 ml of sterile water for injection, adults - 1-3 ml of 5% solution (2-6 ml of 2.5% solution) per day; Children - 1-2 ml of 5% solution (2-4 ml of 2.5% solution) per day.

Precautions

Caution is prescribed with increased blood coagulation, thrombophlebitis, leaning to thrombosis, diabetes mellitus. It is necessary to control the function of the kidneys and blood pressure, especially when prescribing large doses.

Conditions for storing the drug ascorbic acid with glucose

Keep out of the reach of children.

The shelf life of ascorbic acid with glucose

lyophilisate for the preparation of a solution for intravenous and intramuscular administration 0.05 g - 2 years.

tablets 100 mg + 877 mg 100 mg + 877 - 1 year.

dragee 50 mg - 1.5 years.

Do not apply after the expiration date indicated on the package.

Prices in Moscow pharmacies

Presented information about drug prices is not a proposal for the sale or purchase of goods.

The information is intended solely for comparing prices in stationary pharmacies operating in accordance with Article 55 of the Federal Law "On Creating Drugs" from 12.04.2010 N 61-FZ.

tablets 100 mg + 877 mg 100 mg + 877, 10 pcs.

tablets 100 mg + 877 mg 100 mg + 877, 40 pcs.

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