Hemodez injections. Hemodez: instructions for use and what it is needed for, price, reviews, analogues

The drug Hemodez belongs to the group of plasma replacement solutions, it is used for intravenous administration and IVs. Among patients, it is often called a blood sorbent, because it is used to cleanse the blood of toxins, poisons, and poisonous substances. Externally, Hemodez is a transparent, slightly yellowish liquid.

The drug is produced by many pharmacological companies, for example, Biosintez, Biokhimik. Currently, two types of medicine are produced - Hemodez-N, Hemodez-8000, they differ in the concentration of active components. The entire composition is represented by substances with a small mass of molecules, which ensures penetration through the natural protective barriers of the body. Contains:

• chlorides of potassium, calcium, magnesium, sodium;
• sodium bicarbonate;
• Povidone-8000.

The medicine is presented in pharmacies in bottles, plastic containers, bottles of 100-500 ml, the price for 500 ml is about 110 rubles. Indications for the use of Hemodez are varied, because it has the following effects on the body:

• Plasma replacement;
• antiplatelet;
• detoxification.

After administration, the active component Povidone-8000 binds toxins that have spread through the blood and removes them with the participation of the kidneys. The remaining components are related to the body, they optimize electrolyte balance, enhance the filtration function of the kidneys and diuresis. Up to 85% of the main component is excreted within 4 hours, the remaining portion leaves the body within 24 hours without being absorbed into the tissues.

Action for blood purification

The solution contains chlorides of potassium, calcium, sodium, magnesium, sodium bicarbonate, low molecular weight povidone (it has a different molar mass in the line of drugs). If there is no medicine, the doctor will prescribe Neohemodez, a substitute medicine with a similar composition.

Action of the drug:

1. The active substance (low molecular weight povidone) binds toxins circulating in the blood and removes them.
2. Does not allow stasis of red blood cells (means a temporary stop in blood flow). A condition that occurs in cancer patients, alcohol poisoning.
3. Increases diuresis, improves the filtration function of the kidneys.

In some cases, the Hemodez dropper is used in conjunction with albumin and gamma globulin.

Hemodez - properties of the drug

The composition of this blood cleansing medicine differs in the following components:

• potassium chlorides;
• sodium bicarbonate;
• low molecular weight povidone;
• calcium chlorides;
• magnesium chlorides.

In the line of drugs there is “Hemodez” with different molar mass povidone. If the drug is needed, but could not be found at the nearest pharmacy, the doctor, as a rule, prescribes a substitute such as Neohemodez. This medicine has a similar composition.

The properties of the drug directly depend on the components of Hemodez. The action of the drug is characterized by:

• low molecular weight povidone binds and removes toxins circulating in the blood;
• prevents stasis of red blood cells, making it impossible to stop blood flow;
• increases diuresis;
• improves the filtration functions of a paired organ such as the kidneys.

Also, in some cases, the drug may be supplemented with gamma globulin or albumin.

International name

Povidone+Sodium chloride+Potassium chloride+Calcium chloride+Magnesium chloride+Sodium hydrocarbonate

Group affiliation

Detoxifying agent

Release form and composition

The medication is produced in the form of a clear, light yellow solution intended for parenteral (bypassing the gastrointestinal tract) administration.

100 ml of Hemodez solution contains:

• 6 grams of low molecular weight medical povidone with a molecular weight of 8000±2000;
• 500 mg sodium chloride;
• 50 mg calcium chloride;
• 42 mg potassium chloride;
• 23 mg sodium bicarbonate;
• 500 mcg anhydrous magnesium chloride;
• Water for injection as an auxiliary component.

The drug is sold in bottles of 100, 200, 250, 400 or 500 ml, which are packaged in cardboard boxes.

Active substance

Potassium chloride + Calcium chloride + Magnesium chloride + Sodium bicarbonate + Sodium chloride + Povidone-8000 (Potassium chloride + Calcium chloride + Magnesium chloride + Sodium hydrocarbonate + Sodium chloride + Povidone 8000).

pharmachologic effect

Detoxification, plasma replacement, antiaggregation.

Pharmacodynamics and pharmacokinetics

The effects of a drug are determined by the action of its main active substance- low molecular weight polyvinylpyrrolidone, which, after intravenous administration, binds toxins circulating in the bloodstream and promotes their rapid elimination from the body.

The molecular weight of polyvinylpyrrolidone in the preparations Hemodez N and Gemodez 8000, in contrast to the usual Hemodez, is significantly lower, and therefore their detoxification qualities are improved, and the time for elimination of toxins by the kidneys is reduced. The drugs increase glomerular filtration, renal blood flow and increase diuresis.

Polyvinylpyrrolidone is not metabolized in the human body and is fairly quickly excreted in the urine (a small part in feces). 80% of the drug is eliminated within 4 hours, the remaining 20% ​​within 12-24 hours.

Dosage form

Solution for infusion

Indications for the use of the remedy

Most often, the medicine is prescribed for acute conditions associated with injuries, serious illnesses and poisoning. Indications for use are:

• dehydration and intoxication due to acute intestinal infections– salmonellosis, shigellosis, dysentery, staphylococcal food infections, rotavirus and enterovirus infections;
• severe burns with the development of burn disease, trauma with large blood loss;
• state of shock caused by bleeding - pulmonary, from the gastrointestinal tract, etc.;
• blood loss from the body during surgical interventions;
• poisoning with heavy metals and other chemicals.

Hemodesis is also administered for other infectious pathologies accompanied by acute bacterial intoxication - pneumonia, peritonitis (inflammation of the peritoneum), generalized blood poisoning.

Hemodez is given to newborns in case of development of toxemia or intrauterine infection with infectious diseases.

Hemodez is also prescribed for the treatment of hyperthyroidism in complicated forms, acute liver failure, radiation damage to the body, myocardial infarction, early toxicosis and late gestosis in expectant mothers.

Scope of application

• intestinal infections of any kind that poison the body (dysentery, intestinal obstruction);
• poisonings and disorders of the gastrointestinal tract, including alcohol intoxication;
• peritonitis;
• aggravated liver diseases;
• shock after injury and surgical intervention;
• burns;
• intrauterine diseases and toxicity of infants;
• gestosis of newborns;
• heart attack conditions, used as a means of combating arrhythmia;
• toxicosis of pregnant women.

Is it necessary or not to use hemodez?

This drug has been in the forefront among popular ones for a long time. medicines, because there were few analogues, and no negative effects were identified. There was an opinion that hemodez contains narcotic drugs in small quantities, which makes the process easier, but does not cause addiction.

In practice, the composition includes a water-salt solution, which includes 6% low molecular weight polyvinylpyrrolidone, as well as sodium, magnesium, calcium, potassium and chlorine ions. In practice, the positive result was based on the placebo effect, while the harm to the body was also insignificant:

• Regardless of the assurances, the drug was addictive;
• often became the cause of kidney disease (reduction of diuresis). The effect is especially noticeable in people who already have diseases in this area;
• decline blood pressure(HELL). The decrease does not occur particularly sharply, so if there is a tendency, then you had to keep additional drugs on hand;
• lack of air and redness of the face.

In many countries, hemodesis is prohibited for clinical practice, and new drugs have been introduced to replace it. All the drugs that replace it have similar side effects, but their price is much higher, although the powers that be try not to pay any attention to this. If you pay attention to each new drug taken separately, it mostly affects not only blood pressure and kidneys, but also the liver, heart and a number of other points.

Directions for use and dosage of Gemodez

Hemodez solution is administered intravenously at a rate of 40 to 80 drops per minute. The specific dosage is determined by the attending physician individually for each patient, depending on the patient’s age and the severity of his condition.

A single dose for adults is 200-500 ml. The one-time volume of the drug for children depends on their age: for infants - 2.5 ml per kilogram of body weight, for children 2-5 years old - 100 ml, for children 5-10 years old - 150 ml, 10-15 years old - 200 ml .

Depending on the severity of intoxication, the duration of treatment can be from one to ten days. For poisoning (intoxication), acute gastrointestinal infections, as well as for radiation and burn diseases, 1-2 injections are sufficient, for toxemia and hemolytic disease newborns - from two to eight infusions per day (daily or every other day), patients with large-focal myocardial infarction are administered 200 ml once, and in severe conditions - the same amount on the second day.

Hemodez intravenously

The use of Hemodez for treatment is permitted only under medical supervision in a hospital.

The drug is to be administered intravenously by drip. The rate of administration is from 40 to 80 drops per minute. Depending on the age of the patient and the severity of intoxication, the dosage of the drug for treatment is calculated.

For children, the initial dose is set at the rate of 2.5 milliliters per kilogram of body weight.

The drug is administered in the dose that will be determined once or twice a day, depending on the severity of the intoxication lesion.

Hemodez dropper

There is a definition of the maximum single dose, beyond which it is unacceptable to go. When calculating the dosage, the guideline was based on age.

For adults, the maximum single dose should not exceed 400 milliliters.

For children from 10 to 15 years of age, the maximum single dose should not exceed 200 milliliters.

For children from 6 to 9 years of age, the maximum single dose should not exceed 100 milliliters.

For children from 2 to 5 years of age, the maximum single dose should not exceed 70 milliliters.

For children under 1 year of age, the maximum single dose should not exceed 50 milliliters.

Solution "Hemodez": instructions for use

This medicine should not be used alone. Only a doctor can prescribe the drug “Hemodez”. The instructions for use contain only general recommendations. The specialist will determine the maximum one-time amount of the drug, the duration of therapy, the frequency of procedures, etc. After all, in this case, everything depends on the age and weight of the patient, as well as the form and severity of the disease present.

The Hemodez drip can only be placed in a hospital setting under supervision medical personnel. The rate of administration is 40-80 drops per minute (it can be reduced if necessary). Before the procedure, the solution is warmed to 35-36 degrees. As a rule, a single dose for adults is 300-500 ml.

If intravenous administration is not possible, the solution can be administered subcutaneously, but in such cases the effect of therapy will be less pronounced.

A single dose for children is 5-10 ml per kilogram of body. For example, the maximum amount of solution for infants is 50-70 ml. Children aged 2-5 years usually receive 100 ml.

The number of repeated procedures depends on the patient's condition. For example, in case of a large-focal myocardial infarction of the patient, as a rule, 200 ml of solution is administered once, and if there are complications, the infusion is repeated again. For neonatal toxemia and hemolytic disease, the solution can be administered 2 to 8 times a day. Radiation and burn disease, as well as toxic diseases digestive tract requires 1-2 injections. The duration of therapy ranges from 1 to 10 days depending on the severity of the patient's condition.

Does Gemodez-N help with alcohol poisoning?

Hemodez infusions are often used to normalize the condition of an overdose of drugs and alcohol; the medicine is one of the first aid remedies in such situations. However, it is important to know that Hemodez is contraindicated for people suffering from renal failure and individual sensitivity to the drug. It is usually not possible to identify these factors under extreme conditions. Therefore, emergency infusion of Hemodez is permissible only in cases where the potential benefit exceeds potential harm side effects.

The medicine has not been tested during pregnancy and lactation, and its effect on the ability to drive has not been studied. Some doctors use Hemodez to cleanse the blood for lipomas, psoriasis and eczema, but it is not recommended to use the medicine independently for these purposes. Since the drug is not involved in metabolic processes, there is no evidence of overdose.

This medicine is intended for use in a hospital, under the direct supervision of medical personnel. Sold in the pharmacy strictly according to prescription. The shelf life of Hemodez is 3 years; when frozen, the drug does not lose its therapeutic functions, however, the recommended storage temperature is 0-20 degrees Celsius.

Instructions for use

Despite the fact that the drug can be administered intravenously at a slow pace, it is safer and more effective. drip introduction or infusion-transfusion infusion. For the latter option, special transfusion systems are used in hospitals.

The specific dosage will be calculated taking into account the type, severity of the pathology, and the age of the patient. Usually droppers are given twice a day for 2-10 days. A single dosage for an adult is 0.2-0.5 l, for a child – 5-10 ml/kg of weight. Usually, up to 70 ml is infused at a time for children under two years of age, up to 100 ml for children up to five years of age, and by the age of 10 years, the dose can be increased to 150 ml.

Before the procedure, Hemoden must be warmed up so that its temperature approaches the temperature of the human body.

Features of treatment with the drug are as follows:

For intestinal pathologies, procedures are performed once a day, in severe cases - twice a day, for myocardial infarction - once a day as the patient is admitted to the hospital in a volume of 200 ml.

special instructions

Hemodesis can only be used in a hospital setting. Before administration, the doctor must check the integrity and tightness of the packaging; the solution must be transparent, without sediment, suspension or mold. Before infusion, the drug is warmed to body temperature (36-38ºC). For extensive burns, Hemodez is administered simultaneously with plasma, albumin and gamma globulin.

Freezing (either single or multiple) does not affect the quality of the drug. Just before using Hemodez, bottles with frozen solution must be kept until completely thawed at room temperature.

It should be borne in mind that when mixing Hemodez with solutions containing phosphate ion and/or carbonate ion, a precipitate may appear. During treatment with this medication, the patient’s general condition and especially his blood pressure should be monitored.

During pregnancy (and lactation)

If necessary, use during the period breastfeeding, it must be stopped for the duration of therapy.

For children

Both drugs are used in accordance with the recommended doses and indications.

In old age

Information is absent.

Features of use for burns and radiation sickness

The drug is necessary for the rapid removal of intoxication products. For radiation and burn diseases, intravenous administration of a clear solution is indicated 1-2 times in 24 hours, no more. Next, the attending physician monitors general condition patient, prescribes symptomatic treatment. For medical reasons, repeated drip administration of this medication cannot be ruled out. For complicated burns, Hemodez infusions are supplemented with the introduction of Albumin, plasma, and gamma globulin.

Prescription for large-focal myocardial infarction

The use of Hemodez infusions is appropriate for cardiovascular pathologies of the body. The drug is prescribed for large-focal myocardial infarction according to the following scheme: the first day - drip administration of 200 ml once; in case of complications, a similar dose is administered again the next day. Further treatment is symptomatic and takes place in a hospital setting.

With alcohol

Gemodez 8000 and Gemodez N for alcohol poisoning are used directly to relieve alcohol intoxication. A single dose of one or the other drug is usually 400 ml with possible repetition after 12 hours. Therapy is carried out in a hospital setting, taking into account all contraindications and under the supervision of a doctor.

Interaction

Sharing with others medicines may lead to a decrease in their pharmacological effectiveness.

Drug interactions

Hemodez can be combined in complex therapy with other medications – poleglucin, various saline solutions, red blood cell mass, albumin. For acute kidney failure, which arose during surgery, the drug can be used in conjunction with osmotic diuretics (mannitol).

Side effects of Hemodez

According to numerous reviews from patients who were treated with Hemodez, when the solution is administered slowly, the drug usually does not cause complications.

If the permissible speed is exceeded, a decrease in blood pressure, difficulty breathing and the development of tachycardia may occur. In these cases, the patient must be given intravenous calcium chloride, cardiac and vasoconstrictor drugs.

If you have hypersensitivity or intolerance to any component of Hemodez, an allergic reaction may occur, including anaphylactic shock. Such patients should immediately stop the infusion and implement symptomatic therapy: administer a glucocorticoid, as well as a vasopressive, cardiotonic and antihistamine.

Allergic reactions

Doctors pay special attention to the potential risk of developing anaphylactic shock. The phenomenon is rare, but medical practice occurs more than once. In this case, it is necessary to urgently stop administering this medication and carry out symptomatic therapy with the direct participation of glucocorticoids, cardiotonic, vasoconstrictor, and antihistamine vasopressive drugs. The attending physician determines the daily dose and course of therapy on a purely individual basis, strictly according to medical indications.

Overdose

An overdose of Gemodez N and Gemodez 8000 is unlikely.

Contraindications and side effects

The use of Hemodez has a number of contraindications that must be strictly observed. That is why, before carrying out the first procedure, it is important to carry out all the necessary diagnostic measures, as a result of which an accurate diagnosis will be established. The drug should not be administered under the following conditions:

If you take into account all the contraindications and administer the drug correctly, there are practically no side effects observed. But against the background of too rapid administration, a drop in blood pressure, arrhythmia, and breathing problems are possible. Treatment is the use of glycosides, adrenomimetics, calcium chloride. The most serious complication may be anaphylaxis as an allergic reaction to the components of the drug.

In this case, the administration of Hemodez is stopped, an injection of Prednisolone is given, and other symptomatic therapy is carried out.

Analogues and other information

Among the analogues of action, the following drugs are sold in pharmacy chains.

If a person has large burns, a plasma transfusion and albumin injection are performed together with Hemodez.

Overdose is unlikely. The drug combines well with most drugs, but when administered simultaneously, due to its absorbent properties, a decrease in effectiveness may occur.

Other analogues of Hemodez

According to the composition of active ingredients, that is, structural analogues of Hemodez are: Belvidon, Hemosan, Neogemodez, Krasgemodez.

By belonging to one pharmacological group, mechanism of action and similarity of effects on the human body, the following drugs are analogues of Hemodez: Albumin, Alburex, Venofundin, Volecam, Volemkor, Voluven, Volulight, Geloplasma, Hemostabil, Gluconeodez, Dextran, Infucol GES, Neorondex, Plasmubin, Plasmalin, Poliglyukin , Polyglyusol, Polyoxidin, Polyfer, Reogluman, Reopoliglyukin, Rondex, Tetraspan and others.

Drug substitutes

The production of analogues of Gemodez is officially permitted on the territory of the Russian Federation. These medications have less side effects, provide sustainable therapeutic effect strictly for medical reasons. Below is short description so-called “substitutes” for Gemodez:

1. This is the yellow solution needed to carry out infusion therapy. The active components bind toxic substances and quickly remove them from the affected body. Hemodez N has a gentle effect, side effects occur less frequently than after using the original.
2. Hemodez 8000. This is a transparent solution white, which is bottled in glass bottles of 200 ml and 400 ml. It is available with a prescription and can be used strictly as prescribed by a doctor. Duration of treatment – ​​10 days, administer the medicine by drops – 40-80 drops per 1 minute.

Difference between Hemodez and Hemodez N

Hemodez N is characterized by a lower molecular weight of povidone. Unlike the first, it is excreted faster by the kidneys and has a detoxifying effect.

Since 2005, Hemodez has been prohibited in pharmacology and medicine. Russian Federation, analogues are used instead. The product is currently discontinued.

Review of analogues

Analogues of Hemodez for blood cleansing

The listed medications are sold in pharmacies. Use as prescribed by a doctor; the drug is dispensed from pharmacies according to a prescription.

Synonyms (generics)

Preparations with the same active ingredient: Povidone + Sodium chloride + Potassium chloride + Calcium chloride + Magnesium chloride + Sodium bicarbonate (Povidone + Sodium chloride + Potassium chloride + Calcium chloride + Magnesium chloride + Sodium hydrocarbonate) Hemodez-N from 48.00 rub. Gemodez-8000 from 104.14 rub. Belvidon, Gemodez-N-Senderesis, Gemodez-N-Cinco.

Synonyms

• Neohemodesis;
• Krasgemodez 8000.

Cheap analogs of Gemodez

Name Price in Russia Price in Ukraine

When calculating the cost of cheap analogues of Gemodez, the minimum price was taken into account, which was found in the price lists provided by pharmacies

Medicines on request “Intoxication”

You may be interested in the popular drugs that we selected for the query “Intoxication”. The following drugs may not be analogues of GEMODEZ, but may be similar in indication and solve the same problem.

ENTEROSGEL

The drug Enterosgelum is intended to eliminate signs of intoxication and poisoning of the body. Use of Enterosgel by children under the strict supervision of a specialist. 4.4 (21) Intoxication, Stomach, Poisoning, Diarrhea, Infectious diseases.

MEDICHRONAL

Medichronal eliminates the main cause of hangover - acetaldehyde. Medichronal can be used in all situations arising from alcohol consumption (before, during, after) 4.0 (14) Alcohol poisoning, Hangover syndrome, Hangover, Alcohol intoxication.

HUMANA ELECTROLYTE

Humana Electrolyte with fennel and banana is a hypoosmolar remedy to combat dehydration in diarrhea of ​​any etiology.5.0 (1) Diarrhea, Vomiting, Intoxication.

LAKTUVIT

The use of the drug LACTUVIT solves several problems at once: it gently eliminates constipation and naturally normalizes the independent functioning of the intestines 4.3 (8) Constipation, Dysbacteriosis, Intoxication, stool, Laxative.

ALKODEZ IC

The drug Alcodez ІС is effective in treating the symptoms of hangover, alcohol intoxication, chronic alcoholism.5.0 (9) Alcohol poisoning, Hangover syndrome, Hangover, Alcoholism, Alcohol intoxication.

GLUTARGIN

The drug Glutargin is used to treat acute and chronic hepatitis of various etiologies, as a prevention of intoxication and hepatotoxic effects of alcohol, as a treatment for acute alcohol intoxication, mild and moderate, as well as as part of complex therapy of post-intoxication disorders after severe acute alcohol poisoning, including alcoholic encephalopathy and coma.5.0 (3) Gastrointestinal tract, Gastrointestinal tract, Choleretic, Poisoning, Intoxication.

FILTRUM-STI

The drug Filtrum-STI has an enterosorbing, detoxifying, antidiarrheal, antioxidant, hypolipidemic and complexing effect. 5.0 (16) Poisoning, Allergy, Intoxication, Sorbent, Medicines.

ALCO-SORB

The drug Alko-Sorb is effectively used to improve well-being and performance. Promotes the adsorption and removal of toxic substances from the body, reducing symptoms of intoxication, including alcohol. Has an antioxidant effect. Thanks to the presence of taurine, it helps restore energy.4.4 (5) Alcohol poisoning, Hangover syndrome, Hangover, Alcohol intoxication.

SORBOLONG

The drug Sorbolong is an enterosorbent that has a detoxifying effect in case of poisoning of the body.5.0 (2) Intoxication, Stomach, Gastrointestinal tract, Poisoning

NEO SORB

The drug Neo Sorb is an adsorbent, detoxifying and detoxifying agent to improve digestion, sorbs gases, toxins, alkaloids, glycosides, heavy metal salts, salicylates.4.0 (3) Sorbent, Intoxication, Digestion.

ALFA-LIPON

The drug Alpha-Lipon is used with prophylactic and therapeutic purpose as part of complex therapy of diabetic polyneuropathies, liver diseases.5.0 (1) Neuropathy, Poisoning, Metabolic agent, Intoxication.

ALKA-SELTZER

Alka-Seltzer is a hangover cure. The drug eliminates headache and other symptoms of a hangover, also helps to equalize the acid-base balance in the body.4.0 (4) Alcohol poisoning, Hangover syndrome, Hangover, Alcohol intoxication.

ZOREX

The drug Zorex is used in long-term alcohol abuse, chronic alcoholism, hangover syndrome. 5.0 (2) Alcoholism, Hangover syndrome, Intoxication, Medicines.

ALKOFF (ALKO OFF)

The combined drug Alcoff (Alko Off) is intended to eliminate the symptoms of alcohol intoxication as a result of overuse alcohol.5.0 (1) Hangover, Hangover syndrome, Alcohol intoxication.

DIALIPON

The drug Dialipon as part of complex therapy for diabetic polyneuropathy, liver disease (hepatitis, cirrhosis), and chronic intoxication. Polyneuropathy, Liver disease, Intoxication.

L-ELIXIR

Preparation L-Elixir - drops for oral use for cleansing lymphatic system, improves lymphatic drainage of tissues, increases barrier functions lymph nodes, enhances excretion toxic substances from the intercellular environment.4.0 (4) Cleansing the body, Intoxication.

Terms of sale

Solutions Gemodez N and Gemodez 8000 are sold by prescription.

Price in pharmacies

The cost of Gemodez for 1 package is from 116 rubles.

Terms and conditions of storage

Hemodez is a prescription drug. Its shelf life is 3 years, provided that the storage conditions recommended by the manufacturer are observed - dry, cool (at temperatures up to 25ºC) and protected from direct sunlight.

Instructions for the drug Gemodez-N

The drug Hemodez is a solution for infusion that is capable of providing a detoxification effect.

Hemodez composition

A transparent solution with a yellow or light yellow color consists of povidone (polyvinylpyrrolidone), a low-molecular medical molecular weight of which is 8000±2000, as well as sodium chloride, potassium chloride, calcium chloride, anhydrous magnesium chloride, sodium bicarbonate, osmolarity in the required composition of the drug proportions. This entire complex of substances is supplemented with the required amount of injection water.

Hemodez shelf life and its conditions

The drug should be stored at temperatures from 0 to 20 degrees for no more than three years. Places where the drug is stored must be inaccessible to children.

The drug can be frozen, after which it does not lose its properties.

Pharmacology Gemodez (Gemodez-N)

The mechanisms of detoxification action of the drug Hemodez are due to the fact that low molecular weight povidone is capable of binding toxins circulating in the blood and quickly removing them from the body.

The version of the drug Gemodez-N, unlike Gemodez, contains polyvinylpyrrolidone, which has a lower molecular weight, which contributes to its faster elimination from the body by the kidneys and improves the detoxification properties of the drug. Hemodez-N also helps to increase renal blood flow, increase glomerular filtration and increase diuresis.

Hemodesis indications

The drug Hemodez is indicated for use for those patients who suffer from the following diseases:

• Toxic form of acute infectious intestinal disease (dysentery, salmonellosis);
• Peritonitis (in the period after surgery);
• Liver diseases, which are accompanied by the development of liver failure;
• Burn disease;
• Sepsis;
• Hemolytic disease of the newborn;
• Intrauterine infection and toxemia of the newborn.

Hemodesis contraindications

The drug Hemodez has contraindications when its use is undesirable for the patient. Hemodesis should not be prescribed:

• For hemorrhagic stroke;
• For cardiovascular failure;
• At hypersensitivity to the drug.

Hemodez instructions for use

Before using the solution for administration, it must be warmed to a state corresponding to body temperature.

Hemodez intravenously

The use of Hemodez for treatment is permitted only under medical supervision in a hospital.

The drug is to be administered intravenously by drip. The rate of administration is from 40 to 80 drops per minute. Depending on the age of the patient and the severity of intoxication, the dosage of the drug for treatment is calculated.

For children, the initial dose is set at the rate of 2.5 milliliters per kilogram of body weight.

The drug is administered in the dose that will be determined once or twice a day, depending on the severity of the intoxication lesion.

Hemodez dropper

There is a definition of the maximum single dose, beyond which it is unacceptable to go. When calculating the dosage, the guideline was based on age.

For adults, the maximum single dose should not exceed 400 milliliters.

For children from 10 to 15 years of age, the maximum single dose should not exceed 200 milliliters.

For children from 6 to 9 years of age, the maximum single dose should not exceed 100 milliliters.

For children from 2 to 5 years of age, the maximum single dose should not exceed 70 milliliters.

For children under 1 year of age, the maximum single dose should not exceed 50 milliliters.

Use of Hemodez during pregnancy

Data on how effective the drug is and whether its use is safe for a pregnant woman have not yet been provided.

Hemodesis side effects

If the rate of drug administration is exceeded, conditions of arterial hypotension, tachycardia may occur, and the patient may experience difficulty breathing.

Sometimes allergies and even anaphylactic shock may occur.

Overdose

Data on cases of overdose with Gemodez (Gemodez-N) have not been reported.

Drug interactions Hemodez

Descriptions by drug interactions the drug Hemodez (Hemodez-N) is not available.

Additional instructions

If an allergic reaction occurs during the administration of the drug, the infusion should be interrupted and the patient should be treated with symptomatic therapy.

When do they arise? side effects due to the violation of the rate of solution administration, it is necessary to administer a vasoconstrictor and cardiotonic drug.

Hemodez analogues

Analogues of the drug Hemodez are solutions Neogemodez, Krasgemodez 8000, as well as Hemodez 8000, which can successfully replace Hemodez if necessary.

Hemodez price

The drug Hemodez is inexpensive. Its cost varies depending on the volume of the bottle from 57 to 125 rubles.

Gemodez reviews

There are few reviews about the drug, but they all indicate the good cleaning ability of the drug. Those who have experienced the beauty of alcohol poisoning are grateful to the drug for its help. There are also those who, with its help, managed to cleanse the body of drugs. In a word, the drug is able to cleanse the body of a wide variety of toxic contaminants.

Anatoly: The drug Hemodez was received in the form of droppers after removal of purulent appendicitis. I remember that I quickly improved. So, Gemodez saved me from terrible consequences. I can give the drug a positive assessment.

Viktor Sergeevich: I had to use Hemodez only once, when I was hospitalized with severe intoxication from low-quality alcohol. However, two droppers in a day got me back on my feet. The drug is what you need.

Jeanne: How did it happen to me food poisoning, which was caused by seemingly decent canned fish. At first I tried to help myself activated carbon. However, by morning I realized that things were bad and called an ambulance. At the hospital I received help fairly quickly. As far as I understood then in my semi-conscious state, the main culprit in my salvation was the dropper with the drug Hemodez. Well, what can I say, the drug has five stars, which it well deserves.

Similar instructions:

Hemodez has a detoxifying effect due to the binding of low molecular weight polyvinylpyrrolidone to toxic substances circulating in the blood and their rapid elimination from the body. Due to increased glomerular filtration and increased renal blood flow, the drug increases diuresis.

Pharmacokinetics

Up to 80% of hemodesis, unchanged and in combination with toxins and other substances, is excreted in the urine within 4 hours (partially eliminated through the intestines). High molecular weight fractions of the drug are retained by the cells of the monocytic macrophage system.

Indications for use

Hemodez is prescribed as a detoxifying agent for toxic forms of acute gastrointestinal diseases (salmonellosis, dysentery and others), including in children; intoxication of various origins (cancer, radiation, postoperative, alcohol, intoxication due to renal and liver failure), burn disease in the intoxication stage, peritonitis, septic conditions, toxicosis of pregnant women and other pathological processes accompanied by intoxication.

Contraindications

The drug is contraindicated in cases of severe cardiopulmonary decompensation, cerebral hemorrhage, bronchial asthma, acute and chronic diseases kidneys, severe allergies, immunosuppressive conditions.

Directions for use and doses

Hemodez is administered intravenously at a rate of 40-80 drops per minute. Before administration, the solution is heated to +35 - +37 0 C. Adults are administered a single dose of up to 300-400 ml (sometimes up to 500 ml) of the drug. Children are given a single dose: infancy- at a dose of 4-5 ml/kg body weight (maximum volume - 40 ml), from 2 to 5 years - 70 ml, from 5 to 10 years - 100 ml, from 10 to 15 years - 150 ml. Repeated infusions of hemodez are carried out no earlier than 10-12 hours after the end of the previous infusion. The number of injections and the total amount of injected solution depend on the nature and course of the pathological process. For acute gastrointestinal diseases and intoxications, for burn disease in the intoxication phase (1-5 days of illness) and in the intoxication phase of acute radiation sickness, 1-2 infusions are usually given, for hemolytic disease and toxemia of newborns - from 2 to 8 infusions (daily or 2 times a day).

The administration of the drug, especially in severe conditions of patients, requires medical supervision.

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Side effect

When administered slowly, hemodez is usually well tolerated. When infused with increased speed hypotension, tachycardia, difficulty breathing are possible, which requires stopping the administration of hemodez and prescribing calcium chloride (intravenously), mezaton, cardiac drugs, polyglucin.

The product is a drug for effective detoxification and plasma replacement effects. The drug is a drug that provides a detoxifying effect due to the influence of the polyvinylpyrrolidones included in its composition. Such components ensure binding and rapid removal of toxins circulating in the blood. Hemodez differs from its analogues in its low molecular weight, which significantly increases its sorption capacity and ensures a high rate of elimination of decay products by the kidneys from the body. The active component is metabolized and completely eliminated from the consumer’s body within 24 hours.

Dosage form

The drug Hemodez is produced in the form of an infusion solution intended for drip use.

Description and composition

The drug Hemodez is produced in the form of a solution intended for drip use. The product has a transparent, yellow. Sold in special bottles for blood substitutes of 100, 200, 400 ml. The drug contains poleprovinylpovidone, potassium chloride, sodium chloride, calcium chloride, magnesium chloride, anhydrous sodium bicarbonate. The drug is produced in the form of an infusion solution. The drug has no other forms of release.

Pharmacological group

The drug Hemodez provides disinfection, plasma replacement, and antiaggregation effects. These drugs determine the influence of its active component - low molecular weight polyvinylpyrrolidone, which, after intravenous administration, binds toxins circulating in the bloodstream and ensures their rapid removal from the human body.

Molecular mass active substance in the drug Hemodez is significantly higher, and therefore its verification qualities are increased, and the half-life of toxins by the kidneys is reduced. The drugs provide an increase in glomerular filtration and enhance renal blood flow, and normalize the natural diuresis of polyvinylpyrrolidone in the human body, are not metabolized and are quickly eliminated from the patient’s body. About 80% of the drug is eliminated within 4 hours, the remaining 20% ​​is eliminated after 12 hours.

Indications for use

The list of indications for the use of the Hemodez infusion agent can be presented as follows:

• state of shock;
• intoxication with various diseases gastrointestinal tract;
• intoxication due to peritonitis;
• in the period after surgery;
• liver dysfunction;
• thyrotoxicosis;
• intestinal obstruction;
• burn disease;
• sepsis;
• radiation sickness;
• hemolytic disease of the newborn;
• heart attack in the acute phase;
• toxicosis of pregnant women;
• toxemia of newborns;
• intrauterine infection.

for adults

Patients of this age category can use drug if there are indications for use. The drug is administered intravenously, by drip. The rate of administration of the drug is determined individually and is 40-80 drops per minute. Subcutaneous administration of the drug is acceptable, but the effectiveness of the drug is less pronounced.

for children

The drug can be used in pediatric practice if there are indications for use. The product is well tolerated adverse reactions against the background of use is not traceable. The drug Hemodez should be used in accordance with the recommended doses.

The products are often used during pregnancy and breastfeeding to eliminate toxicosis in pregnant women. In the course of statistical studies carried out on the process of using the drug, it was not possible to identify any teratogenic effect. Medicine well tolerated, no adverse reactions observed. No process disturbances were identified when using the product by pregnant women.

Contraindications

The list of contraindications to the use of the composition can be presented as follows:

• intracranial hypertension;
• hypersensitivity to the components of the product;
• acute condition after traumatic brain injury;
• hemorrhagic stroke;
• acute allergic reactions;
• cardiovascular failure;
• respiratory failure;
• thromboembolism;
• anuria;
• oliguria;
• acute thrombosis;
• bronchial asthma;
• diabetes.

Applications and dosages

The dosage regimen is determined individually and depends on the patient’s age and the severity of his pathology. The drug is administered once or repeatedly up to 2 times a day. The duration of the treatment period can be from 1 to 10 days. The duration of therapy also varies significantly depending on the severity of intoxication in the body.

for adults

The drug is administered intravenously, by drip. The rate of administration of the composition is from 40 to 80 drops per minute. Subcutaneous infusions of the product are acceptable, but the effectiveness of the composition is significantly reduced. A single dose of the drug for patients of the adult age category is 200-500 mg. Maximum daily dose is 1000 ml per day. For acute gastrointestinal infections, burn disease and radiation sickness, the drug can be administered up to 8 times a day. The administered dose is 200 mg.

for children

The drug can be used in pediatric practice. A single dose for children is determined from the proportion of 5-10 ml per 1 kg of body weight. The maximum single dose for children under 1 month of age is 50-70 ml. For children aged 2 to 5 years - 100 ml, for children aged 5-10 years - 150 ml, children aged 10-15 years are given 200 mg once. Infusions are often repeated, but not more than 2 times a day. Higher doses may be used to relieve acute conditions.

for pregnant women and during lactation

Dosages for women during pregnancy are determined individually and depend on the woman’s condition and the nature of her toxicosis.

Side effects

Adverse reactions associated with the use of the composition appear sharply; as a rule, with drip administration, no complications are observed. If the recommended rate of administration is exceeded, a decrease in blood pressure, difficulty breathing and the development of tachycardia may occur. In this case, resuscitation measures involve the administration of cardiac and vasoconstrictor medications. In rare cases, serious allergic reactions may occur.

Interaction with other drugs

Concomitant use of the drug with other drugs may cause a decrease in therapeutic effectiveness.

special instructions

Under the influence of the drug, the patient's body temperature can significantly decrease. Before injecting the composition, you should ensure the integrity and tightness of the primary packaging. The composition must be transparent and not contain foreign inclusions. The presence of such formations may indicate improper storage of the drug.

Overdose

The likelihood of overdose symptoms when using the drug in doses recommended by the instructions is minimal. Cases of overdose have not been recorded in therapeutic practice to date.

Storage conditions

The drug Hemodez should be stored at a temperature of no more than 20 degrees. Freezing the drug is prohibited. The product is sold to the public through a network of pharmacies by prescription.

Analogues

The model drugs have a sufficient number of analogues. Other agents that have a detoxifying effect can be considered as substitutes for such a drug.

The medicinal product contains natural ingredients. It has high characteristics and is used for diseases of various etiologies. The composition helps to cope with allergic reaction And alcohol intoxication. Able to quickly relieve diarrhea and other symptoms of poisoning.

Price

The cost of Gemodez is on average 90 rubles. Prices range from 55 to 145 rubles.

The drug is available in the form of an infusion solution. Depending on the manufacturer, the solution is bottled in bottles of 100, 200, 250 or 400 ml.

pharmachologic effect

Detoxification, plasma replacement, antiaggregation.

Pharmacodynamics and pharmacokinetics

The effects of a drug are determined by the action of its main active substance - low molecular weight polyvinylpyrrolidone , which, after intravenous administration, binds circulating in the bloodstream and promotes their rapid elimination from the body.

Molecular mass polyvinylpyrrolidone in the preparations Gemodez N and Gemodez 8000, in contrast to the usual Gemodez, is significantly lower, and therefore their detoxification quality, and also reduces the removal time toxins kidneys. Drugs increase glomerular filtration , renal blood flow and strengthen diuresis .

Polyvinylpyrrolidone It is not metabolized in the human body and is excreted quite quickly in the urine (a small part is excreted in feces). 80% of the drug is eliminated within 4 hours, the remaining 20% ​​within 12-24 hours.

Indications for use of Hemodez

Indications for use of Gemodez N and Gemodez 8000 are:

• state of shock , due to burns, injuries, blood loss, as well as due to surgery;
• for gastrointestinal diseases, including, and salmonellosis ;
• intoxication at peritonitis V postoperative period;
• with the formation of liver failure;
• intestinal obstruction;
• burn disease ;
• sepsis ;
• acute radiation sickness ;
• pneumonia ;
• in the acute phase;
• toxicosis of pregnant women ;
• toxemia newborns and intrauterine infection .

Contraindications

• hypersensitivity;
• condition after TBI;
• hemorrhagic ;
• (severe character);
• cardiovascular failure (2-3 degree);
• respiratory failure;
• oliguria ;
• spicy nephritis ;
• phlebothrombosis ;

Side effects

As a rule, slow administration of the drug does not cause any complications.

If the recommended rate of administration is exceeded, it is possible: shortness of breath and development, which may require introduction cardiac And vasoconstrictor drugs, calcium chloride.

In rare cases, the development of serious allergic manifestations, including . In such cases, the infusion should be stopped immediately and symptomatic treatment should be carried out, which consists of administering cardiotonic And antihistamines funds, vasopressive drugs, glucocorticoids .

Hemodez, instructions for use (Method and dosage)

Instructions for use of Gemodez 8000 and Gemodez N recommend administering the drugs only by drip (infusion), through a special transfusion system .

Drug doses are calculated based on severity intoxication , as well as the age of the patient. Infusions are carried out once or twice a day for 1 to 10 days.

Adult patients, depending on condition and cause intoxication , they recommend infusion of a single dose - 200-500 ml.

The pediatric dose is calculated at the rate of 5-10 ml per kilogram of body weight.

• under 2 years of age - 50-70 ml;
• at the age of 2-5 years - 100 ml;
• at the age of 5-10 years - 150 ml;
• at the age of 10-15 years - 200 ml.

At burns , gastrointestinal infections And radiation sickness administration is carried out 1-2 times in 24 hours.

At toxemia And hemolytic disease In newborns, infusions are carried out 2-8 times a day, every day or with a break of 24 hours.

At myocardial infarction (large focal) a single drip of 200 ml is prescribed on the first day, in case of complications it is repeated on the second day in the same volume.

Overdose

An overdose of Gemodez N and Gemodez 8000 is unlikely.

Interaction

Concomitant use with other drugs may lead to a decrease in their pharmacological effectiveness.

Terms of sale

Solutions Gemodez N and Gemodez 8000 are sold by prescription.

Storage conditions

Vials with the solution should be stored at temperatures up to 20 °C. Freezing drugs (down to -45 °C) does not reduce their quality.

Best before date

Both drugs remain effective for 3 years.

special instructions

Before infusing drugs, it is necessary to check the integrity and tightness of the primary packaging. Solution The drug should not contain foreign matter and be visually transparent.